Thisen sang i neih avangin i chau reng em? Erythropoietin chungchang hi han sawi ila!

A châng chuan chau leh nunna nei loin i inhria em? Hei hi a chhan pakhat chu taksaa thisen sen (red blood cells) a tlahniam vang a ni. Kan taksa hian hormone pawimawh tak a nei a, chu chuan heng thisen sen (red blood cells) siam chhuahna kawngah a pui a ni. Chu chu vawiina kan sawi tur hormone chu a ni. A hming chu Erythropoietin, a tawi zawngin EPO a ni.

Erythropoietin hi eng nge ni?

A awlsam zawngin sawi ila, Erythropoietin hi hormone a ni a, kan kal (kidney) atanga siam a ni ber. Ni e, i hre chiang khawp mai, kal kan ngaihtuah hian zun siam chhuah chauh kan ngaihtuah a, mahse kal hian kan taksaah thil tam tak a ti a ni. Chutiang hna pawimawh tak pakhat chu he hormone (EPO) siam chhuah hi a ni. He hormone (EPO) hian kan taksaa thisen sen, chu chu erythrocyte, hrisel taka awm theihna turin a pui a ni.

A châng chuan, doctor-te chuan erythropoietin siam chhuah chi khat chu thisen tlakchhamna enkawl nân an hmang a , a bîk takin chronic kidney disease ang chi dinhmunah chuan. Tin, infiammi thenkhat chuan an performance tihsan nan he damdawi hi an hmang sual bawk. A chhan chu EPO hian an taksa ruh (muscle) thlenga oxygen a tipung a ni. Chu chu dan kalh a ni em? A tha e?

He erythropoietin hming dangte chu erythropoietin, hematopoietin, leh hemopoietin te an ni. Amaherawhchu, an awmzia a inang vek.

Erythropoietin (EPO) hian kan taksa tan eng service nge a pek?

Okay, tunah chuan EPO hian eng nge a tih tak tak tih kan en ang. EPO hnathawh ber chu thisen zam (red blood cells) siam tura puih hi a ni. Heng thisen sen (red blood cells) te hi kan taksa chhunga tissue hrang hranga oxygen phurtu an ni. Oxygen chu energy-ah a inthlak a, chutah chuan kan tissue atang hian carbon dioxide a chhuak ta a ni. I thawk chhuah hian heng thisen sen vek hian chu carbon dioxide chu a paih chhuak thei a ni.

Hei hi thil thleng tlangpui chu a ni: Kan kal (kidney)-a cell chi khat bik chuan kan thisena oxygen level a hniam tih a hriat chuan (EPO) an siam chhuak nasa hle. Chumi hnuah chuan he hormone (EPO) hian kan ruh spongy part, bone marrow chu thisen sen tam zawk siam turin a hrilh a. Factory-a order pek ang maiin han ngaihtuah teh.

Kidney-a cell-te chuan thisenah oxygen a awm tawk tih an hriat chuan erythropoietin siam chhuah a ti tlem a ni. Hei hi thil buaithlak tak, mahse mawi taka control theih a ni.

Mahse, damdawi lam thil thenkhat chuan kal (kidney) atanga EPO siam chhuah zat a nghawng thei a ni. An siam tam lutuk emaw, an siam tling lo emaw pawh a ni thei. Hei hian thisen sen tam lutuk emaw, tlem lutuk emaw-ah harsatna a thlen thei a ni.

Erythropoietin (EPO) level a san chuan eng nge thleng ang?

EPO level hi a inthlau hle a nih chuan, chu chu taksain a mamawh aia tam EPO a neih chuan a tul lovah thisen sen (red blood cells) pawh a pung thei a ni. Hei hi polycythemia kan ti a. Kawngpuiah traffic jam ang mai a ni a, thisen sen (red blood cells) a tam lutuk chuan thisen kal dan a tikhawlo thei a ni.

Hetianga EPO level a san chhan hi engte nge ni?

EPO level hi a tul lo taka a san theihna chhan engemaw zat a awm thei.

• Hun rei tak oxygen level hniam taka inhnim: Hei hi meizuk emaw, tlangram hmuna awm emaw, tuipui atanga sang zawka awmte chungah a thleng thei a ni. Hei hi a chhan chu i chhoh zel chuan boruakah oxygen a tlem zawk vang a ni. Amaherawhchu, tlangram hmuna chengte tan chuan EPO level sang zawk neih chu thil pangngai a ni a, chu chu taksa insiamremna kawng khat a ni.
• Kal natna avanga thisen tlakchhamna (anemia): A chang chuan thisen tlakchhamna hi kal harsatna avanga lo awm a ni lo. Mahse, kal (kidney) hian taksaah thisen sen (red blood cells) a tlem tih an hriat chuan thisen sen (red blood cells) siamna atana pui turin EPO an siam tam zawk thin. Hei hi EPO tihpunna pangngai, tul tak a ni bawk.
• Cancer hmuh tur awm lo: A tlem hle a, cancer chi thenkhat chuan kal (kidney) hian EPO a siam tam lutuk a, a dik lo hle.

Erythropoietin (EPO) level tlahniam chhante chu engte nge ni?

EPO level tlahniam chhan ber leh langsar ber chu chronic kidney disease ( CKD ) a ni. Kidney a chhiat chuan EPO a siam tling thei lo. Hei hian EPO level a ti hniam a ni. Hetiang dinhmun hi EPO level hniam tak nen hian thisen tlakchhamna (anemia) a thlen thei a ni. Kidney hian hna a thawk tha lo a nih chuan harsatna engzat nge a awm theih tih i hmu thei a ni lawm ni?

Tin, Polycythemia Vera an tih hian EPO level a ti hniam thei bawk. Hei hi thisen cancer chi khat a ni. Hetah hian genetic mutation a awm avangin kan ruhro hian thisen sen (red blood cells) a siam tam lutuk a. Tichuan, kal (kidney) te chuan taksaah thisen sen (red blood cells) a tam lutuk tih an hrechhuak a , EPO an siam chhuah chu an ti tlem ta a ni.

Engtin nge erythropoietin (EPO) level hniam hi enkawl a nih?

I EPO level a hniam chuan enkawl dawna tih hmasak ber tur chu a chhan bulpui zawng chhuakin enkawl hi a ni.

EPO level hniam vanga thisen tlakchhamna (anemia) direct-a enkawl dan ber chu recombinant erythropoietin inject hi a ni. Chungte chu erythropoietin-stimulating agents emaw ESAs emaw an ti bawk. Hengte hi natural EPO hormone leh synthetic, a nih loh leh lab-a siam, EPO chi khat an ni. Doctor-te chuan EPO gene chu an clone emaw, an copy emaw a, shot angin an pe che a, chu chuan thisen sen tam zawk siam chhuah a tichak a ni.

Heng (ESAs) vaccine te hi kal natna khirh tak enkawlna atan an hmang ber a ni.Chronic kidney failure avanga thisen tlakchhamna (anemia) enkawl. Cancer chi hrang hrang hmuh tur awm lo thenkhat tan pawh pek thin a ni.

Mahse, heng (ESAs) vaccine te hian side effect engemaw zat a thlen thei a ni. Mi zawng zawngin an hmu vek lo va, mahse mi thenkhat chuan:

• Thisen sang a sang
• Khawsik
• Luak chhuak thei
• Luhai
• Injection na hmuna natna

Hetiang enkawlna chi hi i tan hma hian heng zawng zawng hi i doctor nen sawiho a, zawhna i neih apiang zawh hmasak phawt a pawimawh hle.

Doctor-te hian engtin nge erythropoietin (EPO) level hi an teh?

I doctor chuan thisen test hmangin i EPO level a teh thei ang. He thisen test hian i thisen cell-a inthlak danglamna, polycythemia, anemia, emaw, ruhro natna dang emaw hian EPO siamchhuahna a nghawng em tih hriat theih nan a pui thei a ni.

Thisen i lak huna i tih tur chu hetiang hi a ni:

1. A hmasa berin i kut a vein vel vun chu iodine emaw isopropyl alcohol ang chi thil hmangin silfai ang che.

2. Tichuan, needle te tak te (a tlangpuiin 21 gauge, earring post pangngai aiin a te deuh) hmangin i kut vein pakhat atang hian thisen tlem te chu lakchhuah a ni.

3. Chumi hnuah thisen sample chu lab-ah enfiah turin an thawn leh thin.

Lab-in i thisen sample an test zawh chuan i doctor chuan test result chungchang sawipui turin a rawn call ang che a, zawhna i neih apiang a chhang ang che. A châng chuan i EPO level chu a pangngaia awm mah se, enkawlna dang i mamawh thei bawk. Hei hi i doctor-in a rel ang.

Erythropoietin (EPO) level pangngai chu engzat nge ni tur?

Doctor-te chuan EPO hi milliliter khatah milliunit (mU/mL)-in an teh a. Mi hrisel tak EPO level hi 4 atanga 26 mU/mL inkar a ni thei.

Mahse, i (EPO) test result hi thil engemaw zat a zirin a danglam deuh thei tih hre reng ang che. Entir nan:

• i kum zat
• I biological sex a ni
• I hriselna dinhmun zawng zawng

Chuvangin i doctor hian i result dik tak a zirchiang ang a, i (EPO) level a hrisel leh hrisel loh a hrilh ang che. Number en mai maiin thutlukna siam mai mai suh, okay?

Erythropoietin (EPO) level hi natural taka tihpun theih dan tur engte nge ni?

Chronic kidney disease (CKD) i neih chuan, emaw, EPO level hniam tak nei thisen tlakchhamna i neih chuan, ei leh in leh nunphung tihdanglamna thenkhat chuan i EPO level tlem a tisang thei a ni. Amaherawhchu, hengte hi damdawi lam thurawn nen chauh tih tur a ni.

• Exercise: Research atanga a lan dan chuan exercise i tih fo hian, a chakna tlem (vigorous exercise)-a i taksain oxygen a hmang tam zawk a ni. Chumi hnuah i thluak chuan i taksa chu EPO tam zawk siam turin a hrilh a. Hetiang exercise chi hrang hrang entirnan cycle khalh, jogging, leh swimming te hi a ni.
• Dietary iron: Iron hi hemoglobin siamtu lian tak a ni. He hemoglobin hian kan taksa cell-ah oxygen a phurh luh theih nan a pui a ni. Iron tamna ei tur chu sa sen, artui hring, thin, tofu, leh iron hmanga tihchak ei tur (e.g., cereal thenkhat, chhang, leh pasta) te a ni.

Mahse heng thilte chauh hian danglamna lian tham a thlen lo mai thei a, a bik takin a bulpui dinhmun a nasat chuan. Chuvangin doctor thurawn zawm a pawimawh.

Heng zawng zawng atanga i hriat reng tur thil (Take-Home Message) .

Erythropoietin hi hormone pawimawh tak, pawimawh tak a ni a, chu chuan kan ruhro chu “thisen sen tam zawk siam turin” a hrilh a ni. Mahse, a châng chuan kan taksa hian a rem lo zawngin thisen zam (red blood cells) a siam tam lutuk emaw, a tam lutuk lo emaw a ni. Heng pahnih hian hriselna lamah harsatna a thlen thei a ni.

I chau reng a, i chau reng a nih chuan ngaihthah suh. Doctor i hmu thei a, i thisen (EPO) level i check thei bawk. Chumi hnuah chuan doctor chuan i tana enkawl dan tur dik ber a rawn rawt thei ang. Heng hormone te balance hi nun hrisel tak neih nan a pawimawh hle tih hre reng ang che.