Evans Syndrome hi eng nge ni? Kan sawi dawn nia!

A châng chuan i chau tih i inhria em? A nih loh leh thil tenawm ber atang pawhin thisen chhuah tihtawp i harsat em? I taksa immune system hian i dodal zawnga hna a thawh vang pawh a ni mai thei. Vawiin hian hetiang dinhmun hmuh tur awm lo mahse hriat tur pawimawh tak chungchang kan sawi dawn a ni. Chu chu Evans Syndrome a ni . Ngaihtuah buai suh, thumal awlsam takin engkim kan sawi dawn a ni.

Chuti a nih chuan, Evans Syndrome hi eng nge ni?

A awlsam zawngin, Evans Syndrome hi autoimmune disease a ni . Thil thleng chu kan taksa, immune system humhim tura ngaih sipaite hian tihsualin kan thisen cell thenkhat chu an tichhia tan ta a ni. Keimahni sipai ngeiin kan mite an beih ang mai a ni. Chumi avang chuan kan taksain thisen cell mamawh zat a hloh ta a ni. Hetiang thisen cell tlahniam dan pangngai lo hi damdawi lama cytopenia kan tih hi a ni.

Evans Syndrome vei tam zawk hi thisen sen ( anemia ) leh platelet ( thrombocytopenia an tih) tlahniam hian a tuar hmasa ber a ni. An pahnih bakah hian mi thenkhat chuan thisen var chi khat neutrophils ( neutropenia an tih) an nei tlem thei bawk.

Heng thisen cell chi hrang hrangte hi a tlem chuan kan taksaa thil pawimawh tam tak, oxygen kan neih te, thisen zam (clotting), natna do te hi a nghawng a ni. Chuvangin kan chak lo va, kan chau a, thisen a chhuak awlsam tan a, kan na fo bawk .

Hetiang dinhmun hian mi thenkhat chu a na lo hle thei a, thenkhat erawh chu a na hle thei thung. Tin, a nghawng chu dam chhung zawngin a awm reng lo. A tha ber chu a damdawi awm lo mah se, enkawlna hian a natna lan chhuah dan a thunun thei a, a nghawng pawh a ti tlem thei a ni .

Evans Syndrome natna lan chhuah dan chu engte nge ni?

Evans Syndrome symptoms hi a inang lo thei hle. Eng ang cytopenia nge i neih leh a nasat danah a innghat. Vawi tam tak chu thisen tlakchhamna emaw thrombocytopenia emaw a lo awm hmasa a, a dangte chu a hnuah a lo lang leh thin.

Thisen zam (red blood cell) tlakchhamna ( anemia ) natna lan chhuah hmasak dan : .

Rei vak lo i kal hnuah pawh i chau em? I chau a, i tih thin ang kha i ti thei lo tih i inhria em? I hmai chu a hring deuh niin a lang mai thei. Hengte hi thisen tlakchhamna chhinchhiahna hmasa thenkhat chu an ni :

• Chau lutuk tih mai mai .
• Vun dum (pale) .
• Lu natna emaw luak chhuak emaw .
• Thâwk harsa (dyspnea) .
• Thinlung thawk chak tak (tachycardia) .
• I thinlung a na (heart palpitations) ang maia hriat emaw, a na emaw .

Platelet tlakchhamna (thrombocytopenia) lan chhuah hmasak ber: 1.1.

A chang chuan i vunah hian dot sen te te a lo lang thin tih i hre tawh em? A nih loh leh hliam i tuar mai mai em ni? I ha i sil hian i hmuiah thisen a chhuak tam zawk em? Hengte hi platelet tlahniam chhinchhiahna awm thei te chu a ni:

• Vun hnuaia thisen chhuak (petechiae) sen te te.
• Vunah hian a sen hring (purpura) a awm .
• Bruising (ecchymosis) chhan awm lova lo awm thin.
• Gums emaw hnar atanga thisen chhuak tam lutuk.
• Hmeichhiaah thlasik laiin thisen a chhuak nasa hle.
• Thluak emaw zun emaw hmanga thisen chhuak.

Neutropenia symptoms (hengte hi a hnuah a awm thei a, a lo awm lo thei bawk):

Thla khatah khawsik khat emaw pahnih emaw vei hi thil pangngai a ni. Mahse, khawsik neiin i na fo em? Kawngkhar natna i nei reng em? An dam theih nan hun rei tak an hmang niin a lang em? I neutrophils a hniam laia thil thleng thei thenkhat chu hetiang hi a ni:

• Khawsik.
• Kawngkhar natna a awm .
• Khawsik, khawsik leh pum na fo thin.
• Beng natna lo awm leh thin.
• Hun rei tak chhunga fungal infection awm thei.
• Zun kawng natna (UTIs) .

Evans Syndrome chhinchhiahna dang (hengte hi a chang chuan a awm thei):

• Kawngkhar chhunga lymph nodes a lo hring chhuak.
• Spleen lian tak a awm .
• Liver lian zawk .
• Jaundice a awm a .

Engvangin nge Evans Syndrome hi a lo awm?

Kan sawi tawh ang khan Evans Syndrome hi autoimmune disease a ni . Chumi awmzia chu kan taksa immune system hian kan thisen cell thenkhat chu "hmêlma" tiin a hre sual a, a bei tan tihna a ni.

He hna hi kan immune system-a cell chi khat bik B cells te hian an thawk a ni. Heng B cell te hian antibodies an tih thil an siam thin . Heng antibodies te hian chu thisen cell sual nei lote chu an man a, an tichhia a ni. A tlangpuiin thisen cell chi khat an bei tan a, chutah chuan thisen cell chi dang an bei tan thei bawk.

Hetiang kalphung hi a tawpah chuan thisen cell chi hnih (cytopenia) tal tlakchhamna thlentu a ni a, a chang chuan pathumte pawh a tlakchham tir bawk. An pathum zingah hian tlakchhamna chu pancytopenia an ti a . Heng thisen cell te hi a hniam chhan ber pathumte chu:

• Autoimmune hemolytic anemia (AIHA) avanga thisen tlakchhamna (AIHA) .: Hei hi thisen sen (red blood cells) a tlahniam lai a ni. Chu chu taksain a siam theih aia rang zawkin an tichhia tihna a ni.
• Immune thrombocytopenia (ITP) : Hei hi platelet tlahniamna a ni. Immune system hian thisen atanga platelet awmte chu a bei a, a paih chhuak thin.
• Autoimmune neutropenia (AIN) : Hei hi thisen var chi khat neutrophils a tlahniam thinna a ni. Immune system hian neutrophils te chu a bei a, a tichhia a ni.

Ngaihtuah teh, thisen cell hniam (cytopenia) chhan tam tak a awm thei. A châng chuan ruhro hian thisen cell a siam ṭhat loh vang pawh a ni thei. Mahse, autoimmune cytopenia-ah chuan immune system hian a thisen cell a tichhe vek a ni.

Evans Syndrome thlentu (triggers) te chu engte nge ni?

Scientist te hian heng autoimmune natna te hi engvangin nge an lo awm tih chiang takin an la hre lo. Mahse heng natnate hi natna khirh tak emaw, taksa hriselna lama harsatna nasa tak thlentu thil thleng emaw hnuah a intan fo tih an hmuchhuak a ni. Chungte chu trigger an ti a .

Tin, autoimmune disease pakhat i neih chuan statistically chuan a dang i vei theihna a sang zawk bawk. He immune system disorder hi taksa peng khat atanga hmun dangah a darh ang mai a ni.

Evans syndrome hi a mah chauhin a lo awm thei (hei hi primary Evans syndrome an ti a), a nih loh leh natna dang nena inzawm secondary condition angin a lo awm thei bawk (hei hi secondary Evans syndrome an ti) . Chutianga inzawm theih dinhmun thenkhat chu:

• A rilru a buai em em a, a rilru a hah em em bawk a.
• Immunodeficiency danglam tak a awm tlangpui
• Selective IgA tlakchhamna a awm
• Sjögren-a natna (syndrome) a ni
• Hodgkin ni lo lymphoma a awm
• Lymphocytic leukemia natna rei tak awm thei
• Hepatitis C natna khirh tak a ni
• HIV hrik kai rei tawh tak

Primary Evans syndrome i neih chuan hun engemaw chen natna i neih hnuah a lo awm thei a, a chhan chiang tak i nei lo thei bawk. Scientist te chuan Evans syndrome hi idiopathic condition ah an dah a. Chumi awmzia chu direct cause hmuh a la ni lo tihna a ni.

Evans Syndrome avanga harsatna awm thei te chu engte nge ni?

Evans Syndrome vei zawng zawng hian harsatna an nei vek dawn lo. Mi thenkhat chuan symptoms na lo tak tak chauh an nei thin. Amaherawhchu, natna khirh takah chuan heng thisen cell tlakchhamna (cytopenias) te hi nunna atana hlauhawm tak a ni thei. Entir nan:

• Taksaa oxygen phur thei tur thisen sen (red blood cells) a awm loh chuan thisenah oxygen a awm tlem hle (hypoxemia) . Hei hi thinlung tan a harsa hle a, thinlung natna leh thinlung chak lohna a thlen thei a ni.
• I thisen zam tura puitu platelets , i neih tlem chuan i thisen chu a khalh tha lo. Hei hian awlsam leh rang takin thisen a chhuah tir thei a ni. Hei hian thisen tlakchhamna nasa tak a thlen thuai thei.
• I taksain natna hrik dona kawnga puitu neutrophils , a hloh chuan natna i kai tam zawk a, a nasat phah thei a, i taksa pum puiah a darh thei bawk. Hei hian natna hlauhawm tak sepsis tih a thlen thei a ni .

Doctor-te hian engtin nge Evans Syndrome hi an hriat theih?

Evans Syndrome hi thisen test hmanga hriat theih a ni . Cytopenia symptoms i neih chuan, emaw, routine health check-a thisen cell count tih laiin emaw hriat theih a ni.

I Complete Blood Count (CBC) -ah thisen sen, platelet, neutrophils i hniam tih a lan chuan i medical team chuan test tam zawk an nei ang. Entirnan, i thisenah Evans Syndrome nena inzawm antibodies level sang tak a awm leh awm loh an enfiah ang. Cytopenia thlen thei dinhmun dang, infection thenkhat emaw cancer emaw an awm leh awm loh an enfiah bawk ang.

Doctor-te chuan Evans Syndrome hi a chhan dang zawng zawng chu paih vekin an nemnghet. A châng chuan, an dinhmun dang hriat loh nân CT scan (computed tomography scan) emaw , ruhro biopsy emaw an tih a ngai thei bawk.

Evans Syndrome hi damdawi tluantling a awm em? Engtin nge enkawl a nih?

Dik tak chuan Evans Syndrome, emaw, autoimmune natna dang emaw hi tihdamna famkim a awm lo . Doctor-te chuan heng autoimmune natnate hi i immune system hnathawh tihtlem thei damdawi an pe che a ni.

Tin, i natna lan chhuah dan chu a hranin enkawl theih a ni bawk. Entîr nân, i thisen cell zat a tlem hle a nih chuan, i doctor chuan chu chu a ṭhenah thisen inthlâkna hmangin a siam ṭha thei ang .

Hun rei tak chhunga autoimmune natna tam tak ang bawkin Evans Syndrome hi hun kal zelah a tha chho zel thei a ni. A châng chuan symptoms chu a bo ang maiin a lang thei ( remission an ti) , mahse chutah chuan a lo lang leh thei a, a na zual thei bawk ( relapse an ti).

I dam chhungin enkawlna hrang hrang i enchhin a ngai mai thei, an hlawhtlinna chu hun kal zelah a danglam thei a ni. I doctor chuan Evans Syndrome natna khirh ber ber atanga venhim a tum ang che.

Enkawlnate chu engte nge ni?

Evans Syndrome enkawlna pangngai chu immunosuppressant damdawi leh a tul chuan thisen pek hi a ni. Heng immunosuppressants te hian i immune system-in a beih sual chu a tihtlem avangin hna a thawk a ni.

Damdawi pek chi hrang hrang:

• Corticosteroids , prednisone ang chi te pawh a awm bawk . Hei hi a tlangpuiin enkawlna pek hmasak ber a ni.
• Intravenous immunoglobulin therapy (IVIg) ah hian mihring antibodies awmna solution chu vein kaltlangin pek a ni. Heng antibody tharte hian autoimmune antibodies dik lote chu an binding thei a, an disable thei bawk.

Standard treatment i dawn that loh chuan i doctor chuan treatment dang a lo enchhin thei bawk. Chung zingah chuan:

• Monoclonal antibody , rituximab ang chi te hi a ni . Hengte hi lab-a siam antibody an ni. A châng chuan hengte hian autoimmune response a titawp thei bawk. Damdawi dangin hna a thawh loh chuan i doctor chuan hengte hi a rawn rawt thei ang.
• Splenectomy tih a ni . A nasat chuan i doctor chuan i spleen lakchhuah nan operation neih a rawt thei ang. I spleen hi thisen cell hlui lakchhuahna hmun a ni. Chuvangin spleen an lakchhuah chuan a kalphung chu a slow deuh thin.

Enkawlna hian harsatna emaw, side effect emaw a nei em?

Immunosuppressants i ei hian i immune system-in i autoimmune disease a chhan dan chu a tlahniam a ni. Mahse, natna hrik laka i immunity pawh a tlahniam bawk . Chuvangin natna i neih loh nan fimkhur bik i neih a ngai dawn a ni.

I doctor chuan vaccine i dawn tawh bakah vaccine dang a rawn rawt thei bawk. I immune system a chak loh (immunocompromised) chuan natna pangngai i neih loh tur natna i vei awlsam zawk mai thei.

Evans Syndrome vei nun hian dam chhung a nghawng em?

Evans Syndrome hian i dam chhung a nghawng hauh lo. Mi thenkhat chuan symptoms na lo tak tak, a chang chuan symptoms te chauh an nei thin. Mahse, harsatna ṭhenkhat, thisen chhuah, thinlung natna, leh natna hrik kai te hi nunna atana hlauhawm tak a ni thei.

Secondary Evans syndrome i neih chuan, chu chu chronic condition dang nen i nei tihna a ni a, chu chuan i dam chhung pawh a nghawng thei a ni. I natna dang nen hian nunna atana hlauhawm harsatna i nei thei bawk.

Evans Syndrome vei tan chuan eng nge a hmalam hun?

Evans Syndrome vei te thil tawn hi a inang lo hle. Symptoms hi a na lo emaw, na tak emaw pawh a ni thei. Mi thenkhat chuan an symptoms te chu a bo vek angin an hria (remission). Mi dangte chuan a hnuah an tawng leh thin (relapse).

Mi tam tak chuan enkawlna eng emaw zat leh damdawi lam enfiah fo an mamawh a ni. Enkawlna hian hna a thawk tha fo thin a, mahse a tha reng reng lo. A châng chuan, enkawlnate hlawhtlinna chu hun kal zelah a tlahniam niin a lang thei. Enkawlna dang i enchhin a ngai mai thei.

Evans Syndrome vei lai hian engtin nge ka in enkawl ang?

Evans Syndrome i neih chuan i medical checkup neih fo thin kha i zawm reng a pawimawh . I dam tha hle a nih pawhin i doctor chuan i dinhmun chu enfiah a duh ang a, a na zual chuan a man hma hle ang.

Tin, nangmah hi i ngaihven reng tur a ni a, symptom thar i neih leh neih loh i fimkhur reng tur a ni. I khawsik a dam lo a nih chuan, emaw, thisen chhuah thunun theih loh i neih chuan i doctor ko nghal rawh .

Doctor hnenah eng zawhna nge ka zawh ang?

I doctor hnenah hetiang zawhna hi zawh i duh mai thei:

• Eng ang thisen cell nge ka tlakchham?
• Engzat nge an tlahniam?
• Eng symptom emaw warning sign emaw nge ka fimkhur tur?
• Engtin nge enkawlna hian hna a thawk em tih ka hriat theih ang?
• Enkawlnain hna a thawh loh chuan eng nge thleng ang?
• Engtikah nge ka doctor appointment tur chu ka book ang?

Evans Syndrome hi natna hlauhawm tak a ni a, i hriat ngai loh pawh a ni mai thei. A lan chhuah dan chu mak tak leh tibuaitu a ni thei. Thil thleng leh a awmzia hriatthiam hi thil harsa deuh a ni thei.

Evans Syndrome hi dam chhung zawnga natna awm ni mahse, a inang reng reng lo. I rilru a hahdam ang tih beiseina chu vawng reng la, a tlem berah chuan a chang chuan. Eng ang pawhin awm mah la, i medical team chu i mamawh enkawlna pe turin an awm reng ang.

Take-Home Thuchah hnuhnung ber

Okay, chuvangin kan sawi tawh zinga pawimawh tak tak thenkhat i hriat nawn tir leh ang u.

• Evans Syndrome hi eng nge ni?Natna hmuh tur awm lo tak, nangmah ngeiin i immune system-in i thisen cell a bei thin.
• Hei hian thisen sen ( anemia ), platelet (thrombocytopenia), leh neutrophils (neutropenia) te a tlahniam thei a ni.
• Chauh lutuk, vun rawng hring, hliam awlsam, thisen chhuah tam, leh natna hrik kai fo te ang chi natna lanchhuahna a awm thei.
• Hei hi tihdamna famkim awm lo mah se, a natna lan chhuah dan chu enkawlna hmangin control theih a ni .
• Damdawi lam thurawn mumal tak zawm a, natna lan chhuah dan ngaihven a pawimawh hle.
• Nangmah chauh i ni lo. I doctor leh i hmangaih ten an pui ang che. Positive taka awm reng a pawimawh hle bawk.

He thu hi in tan a tangkai ngei ka beisei. Zawhna i neih chuan Doctor nen inbiakna neih hreh suh.

Evans syndrome, autoimmune natna, cytopenia, thisen tlakchhamna, thrombocytopenia, neutropenia, thisen lama harsatna te