Leivut i khawih emaw, khaw lum laia i chhuah emaw, thil i ei emaw hian i hrual, hives, leh mit sen, tui tak tak i nei bawk em? A chang chuan thawk harsa i ti em? Hei hi ‘allergy’ kan ti fo thin. Chuvangin vawiin hian he allergy siamtu ber pakhat kan sawi dawn a ni. Amah hi histamine a ni. He hming hi doctor hnen atangin emaw, i allergy natna damdawi i ei hming atang emaw pawhin i hre tawh mai thei. Histamine hi eng nge a nih a, taksaah eng nge a tih tih i lo en ang u.
A awlsam zawngin, he histamine hi tu nge ni?
Kan taksa hi ram venhim tha tak angin han ngaihtuah teh. He ramah hian ram dang mi rawn lut mah se, kan taksa tana hlauhawm lo thil pawh (entir nan, leivut chi khat, pangpar hnah, emaw, ei tur chi khat, shrimp ang chi) pawh ni se, kan defence system (immune system) hian a chang chuan hmelma angin a ngai sual thin.
Chutih lai chuan kan immune system-a cell-te hian chemical pakhat an chhuah a, chu chuan cell dangte nen an inbia a, thuchah an inthleng a ni. Vaukhânna thuchah, "Hetah hian hmelma a lo kal a, hma la vat rawh!" Chu palai chu histamine an ti a.
He chemical histamine an tih hi kan taksaah hian cell chi hnih ah a awm ber a ni.
1. Mast cells: Hei hi kan taksa pum puia connective tissue-a awm, thisen var chi khat a ni. A bik takin vun hnuaiah, thisen kalna kawng leh lymph kawng bulah, nerve, lung leh intestines-ah te an tam hle.
2. Basophils: Hei hi thisen a awm, thisen var chi dang a ni.
Thil tha lo tak tak taksaah a lo inhnamhnawih chuan heng cell te hian histamine an tichhuak a, chu chuan allergy symptoms a siam thin. A tlangpuiin heng symptoms te hi taksa hmun khatah chauh a awm a, mahse a chang chuan he reaction hi a na hle thei bawk. Anaphylaxis kan ti a ni . Hei hi emergency a ni a, taksa pum a nghawng a, nunna atana hlauhawm pawh a ni thei.
Histamine hian taksaah eng nge a tih? Hei hi receptor chungchangah eng nge ni?
Histamine hi misual mai mai a ni lo va, allergy thlentu a ni. Taksaah hna pawimawh tak tak engemaw zat a thawk a ni. Histamine hian taksaah eng nge a tih tih hi a inzawmkhawmna receptor-ah a innghat a ni. Chabi pakhatin kawngkhar engemaw zat a hawn theih ang bawkin, i luhna pindan chu eng kawngkhar nge i hawn tih a zirin a danglam ang. Scientist te chuan histamine receptor chi li an hmuchhuak a.
Hei hi chiang taka hrethiam turin han thlir ila.
| Receptor chi hrang hrang | Hmunpui ber berte | Activate a nih chuan eng nge thleng? |
|---|---|---|
| H1 dawngtu a ni | Taksa pumpuiah, a bik takin nerve cell, thawkna kawng, leh thisen kalna kawnga smooth muscle cell-ah te. |
|
| H2 dawngtu a ni | A bik takin stomach acid siamtu cell, smooth muscle cell, leh heart cell-ah te a ni. | |
| H3 dawngtu a ni | Central nervous system (thluak) a nerve cell-ah te. | |
| H4 dawngtu a ni | Bone marrow leh thisen cell lo ni ta cell puitling loah te. |
I hrethiam em? Chumi awmzia chu allergy nia ngai mah ila, histamine hian a rukin kan taksa thil tam takah a inrawlh a, chu chu mut, hriatrengna, zirlai, leh taksa lum leh vawt tihtlem te hi a ni.
Histamine nena inzawm thei damdawi lam harsatna lian ber berte chu engte nge ni?
Allergic condition hi messenger histamine hnathawh vang a ni ber. Entirna thenkhat chu hetiang hi a ni:
- Atopic dermatitis (eczema tia hriat bawk): Vun a vawt a, a sen a, a hring a, a hring nasa hle a, ‘eczema’ tia sawi fo a ni.
- Contact dermatitis: Thil pakhatin vun a tawk a, allergy a awm thin. Entirnan, synthetic fragrances, metal thenkhat (nickel ang chi), leh preservatives te.
- Allergic rhinitis (hay fever tia hriat bawk): Hei hi mi tam takin an tawn fo thin a ni. Leivut, pollen, pet dander, leh leivut mites ang chi thil avanga lo awm a ni a, hnar luang chhuak, hnar luang chhuak, hnar khar a thlen thin.
- Allergic asthma: A chunga kan sawi ang bawk hian a chhan a, mahse hetah hian thawkna kawng a zim a, thawk harsa leh thawk hah a awm thin.
- Allergic conjunctivitis: Allergen avanga mit mitmeng (conjunctiva) a hring, a sen, a hring, a tui a awm thin.
Histamine Intolerance hi eng nge ni?
Hei hi a danglam deuh hlek a ni. A chang chuan kan taksa histamine level a sang lutuk thin. Hei hi taksain histamine a tihchhiat that theih loh vang a ni. Chutiang a lo thlen chuan symptom hrang hrang a awm thei.
- Lu na emaw migraine emaw a awm thei
- Hnar hnar (hnar congestion) a awm
- Chau reng reng
- Hives (hives) a awm
- Chaw ei leh in lama harsatna a awm
- Hmeichhiaah thlasik hun mumal lo
Heng symptoms te hi i neih fo chuan doctor pan a, sawipui a pawimawh.
Chuti a nih chuan engtin nge he histamine hi i control theih ang?
Histamine avanga lungawi lohna thunun nan hian doctor-te’n enkawlna chi hrang hrang an rawt a ni. Hengte hi allergy damdawi tih thumal i hriat hian i rilruah a lo lang thin.
- H1 antihistamines: Heng damdawi hi ‘allergy pills’ tia kan hriat tlangpui te an ni. A chunga kan sawi tak H1 receptor te hi block-in hna an thawk a ni. Hei hian histamine chu chutiang receptor-ah chuan a inzawm lo va, itching leh hives a siam thei lo. Chûngte chu chi hrang hrang a awm a, pill, syrup, cream, leh mittui tlakna te pawh a tel. Ṭhenkhat chu Doctor thupek tel lova ei theih a ni a, mahse i doctor-in eng damdawi nge i tana ṭha ber tih zawt la a ṭha ber.
- H2 antihistamines: Hengte hi pum lam harsatna atan hman a ni ber. Gastritis, gastroesophageal reflux disease (GERD), leh indigestion (dyspepsia) ang chi natna atan an pe thin. Anni hian chaw chhunga acid siamtu H2 receptor te chu block-in hna an thawk a ni.
- Corticosteroids: Hengte hi ‘steroids’ kan ti a. Histamine avanga inflammation awm thin tihziaawmna atan an pui thin. Entirnan, Asthma control nana hman thin inhaler tam takah hian heng steroid damdawi te hi a awm a.
- Epinephrine injection: Hei hi a pawimawh hle. He injection hi nunna atana hlauhawm, allergic reaction na tak, emaw anaphylaxis emaw a awm chuan emergency treatment atan pek thin a ni. Rang takin thawkna kawng a hawng a, thisen sang a siam tha leh bawk.
- Zirna thenkhatah chuan vitamin thenkhat, vitamin C, copper, leh vitamin B6 te hian taksaa histamine level tihhniam nan a pui thei tih hmuhchhuah a ni. Mahse, doctor nena inbiakna hmasa lovin heng supplement zinga pakhat mah ei suh.
Engtikah nge Doctor ka hmuh ang?
Seasonal allergy i neih emaw, thil pakhata allergy symptom i neih emaw a nih chuan, a bik takin nitin hnathawhna tibuaitu a nih chuan doctor pan a pawimawh. I doctor chuan i allergy dik tak hriat tumin test a ti thei a, i tana enkawlna tha ber a rawt thei bawk. Tin, a chunga kan sawi tak histamine intolerance symptoms awm apiang chu i doctor nen sawiho bawk ang che.
Kan taksa hnathawh dan pangngai atan histamine hi a pawimawh viau nachungin, a chang chuan a active lutuk chuan harsatna nasa tak min thlen thei a ni. Chuvangin chutiang lungawi lohna tuar a ngai lo. Heng dinhmunte hi damdawi lam thurawn dik tak lak hian a thunun theih ber a ni.
Take-Home Thuchah a ni
- Histamine hi kan immune system atanga chhuak natural chemical messenger a ni.
- Histamine hi allergy symptom tam tak thlentu ber a ni a, chu chu a hring, thawk hah, leh hnar hrual te hi a ni.
- Histamine hian taksa peng hrang hranga awm H1, H2, H3, leh H4 tih receptor te nen an inzawm a, hna hrang hrang a thawk thin.
- Damdawi antihistamines te hian histamine hnathawh a titawp thei a, allergic symptoms te pawh a control thei bawk.
- I allergy symptoms a nasat emaw, i nitin nun a tibuai emaw a nih chuan doctor pan ngei ngei tur a ni a, thurawn leh enkawl dan dik tak i dawng ang.
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