Taksa chetna thunun theih loh i tuar em? (Tardive Dyskinesia & Chorea) - Ingrezza chungchang hi han sawi ila!

I thunun lohvin i ke ruhte a inher emaw, i hmel lan dan a inthlak emaw chuan a nuam lo hle thei a ni. Nitin hna thawh a harsat phah thei a, mi pali nena inpawh pawh a ti harsa thei bawk. Chutiang dinhmun avang chuan mi tam tak chu an lungngai hle. Nangmah emaw, i hnaih ber tu emaw pawhin hetiang hi i tawng tawh a nih chuan he thuziak hi i tan a pawimawh hle ang.

Tardive Dyskinesia leh Chorea te hi eng nge ni?

A awlsam zawngin, hengte hi kan taksa chetna nena inzawm damdawi lama thil thleng pahnih an ni.

Tardive Dyskinesia (TD): Hei hi kan taksa, a bik takin hmai leh ke ruhte, duh loh zawnga, jerky movement kan neih thinna a ni. Hei hian duh loh vanga lei chhuah te, hmui hrual te, mit hrual te, emaw, ke leh ke ruh hrual te pawh a huam thei. Hetiang dinhmun hi hun rei tak chhunga antipsychotics thenkhat emaw, pum damdawi thenkhat emaw hman avanga side effect angin a awm thei a ni.

Chorea: Hei hi Huntington 's Disease tih hming pu genetic condition avanga chetna lama harsatna a ni. Huntington natnaah chuan thluaka nerve cell te chu a chhe zauh zauh a. Hei hian ngaihtuahna, rilru put hmang thunun leh taksa chetna kawngah harsatna a thlen a ni. Chorea hian kut, ke leh hmai chetna thunun theih loh a siam a.

Damdawi Ingrezza hian he dinhmun pahniha thil thleng , thunun theih loh chetna chu a thunun thei a ni. Mahse, Ingrezza hian Huntington natna lan chhuahna dang (ngaihtuahna lama harsatna ang chi) a enkawl lo tih hre reng ang che.

Engtin nge damdawi Ingrezza hian hna a thawh?

Hei hi hrethiam tur chuan kan thluaka chemical messenger te tak te kan hriat hmasak a ngai a ni. A hming chu Dopamine a ni . A dik tak chuan Dopamine hi neurotransmitter a ni. He Dopamine hi kan taksa che vel control nan a pawimawh hle.

Kan thluak hian dopamine a thawn tam lutuk chuan eng nge thleng ang tih han ngaihtuah teh? Tui tap on rang lutuk ang bawkin, dopamine signal a pun chuan kan taksa chu duh lohvin a lo awm ta niin an ngai .

Hetah hian Ingrezza tih dan chu a awm. Kan thluaka protein pakhat VMAT2 (vesicular monoamine transporter 2) tih chu a target a ni. He protein hi dopamine tihchhuahna atana puitu a ni. VMAT2 activity control hian Ingrezza hian dopamine signaling tam lutuk chu a ti tlem a ni. Faucet on tlem deuh ang mai a ni. Chuvang chuan thunun theih loh chetna chu a tlahniam zauh zauh thin.

He damdawi hi engtin nge ka hman ang?

Ingrezza hi damdawi a ni a, capsule angin a awm a. Chaw ei rual leh ei loh pawhin ei theih a ni. I doctor chuan he damdawi hi a rawn pe ang che. I doctor-in ei tur a tih aia tam emaw, tlem emaw ei ngai suh.

Dose hman dan pangngai chu a hnuaia table-ah hian tarlan a ni a, mahse i doctor chuan i dinhmun a zirin hei hi a thlak danglam thei a ni.

Ingrezza Sprinkle capsule ei dan tur

Mi thenkhat chuan capsule ei harsa an ti thin. Chutiang mite tan chuan "Ingrezza Sprinkle" tih chi khat bik a awm. Hei hi a hman dan tur chu a ni:

1. Fimkhur takin capsule chu hawng la, a chhunga damdawi chi te te (sprinkles) te chu ei tur nem tak, applesauce, yogurt, pudding teaspoon khatah dah la.

2. He damdawi hi chew emaw crush emaw suh .

3. Damdawi nena chawhpawlh chaw spoon khat zawng zawng ei nghal rawh .

4. Tichuan tui glass khat (240 ml vel) in tur a ni.

5. He damdawi hi bawnghnute leh tui nen chawhpawlh ngai suh.

Engtin nge damdawi hian hna a thawk em tih i hriat theih ang?

Clinical study atanga a lan dan chuan Ingrezza i tan atanga kar hnih chhung lek chhungin symptoms ah hmasawnna engemaw zat i hmu thei a ni. Chutiang taksa chetna thunun loh chu a tlahniam zauh zauh tih i hmu ang.

I doctor chuan dose hniam takah a tan tir ang che a, i taksain a chhan dan tur a en theih nan a tul angin a dose chu a siamrem ang. Chuvângin, a rah chhuah ṭha ber hmuh nân hun engemaw chen a la ngai mai thei. I natna lan chhuah dan a tha lo emaw, a zual zel emaw nia i hriat chuan i doctor hnenah hrilh nghal rawh. A dose chu a siamrem thei a, damdawi dang a dah belh thei a, a tul chuan damdawi dang hmangin a thlak thei bawk.

Side effect awm thei leh engtin nge kan enkawl ang?

Damdawi dang ang bawkin Ingrezza hian side effect engemaw zat a nei thei a, mahse mi zawng zawngin an vei lo.

• Tardive dyskinesia (TD) vei zinga side effect awm tam ber chu:
• Mutthilh theih lohna

• Chorea vei zingah side effect awm fo thin:
• Mutthilh theih lohna
• Vun natna (Hives) .
• Vun a hring chhuak
• Mut harsatna

Chûngte chu engtin nge i hmachhawn?

• Mutthilh: He damdawi hian engtin nge a nghawng tih chiang taka i hriat hma chuan fimkhur ngai thil, lirthei khalh emaw, machinery hman emaw ang chi thil tih loh tur.
• Skin rash emaw hives emaw: Hengte hi allergic reaction chhinchhiahna a ni thei. Chutiang a nih chuan doctor ko nghal la, a nih loh leh hospital emergency room (ETU) hnai ber pan rawh.
• Mut theih lohna: Mahni tana i tih theih tur thil a awm. Coffee, tea, leh cola ang chi caffeine awmna in tur tihtlem te, nitin hun khata mut leh harh chhuah te, i mutna pindan thim taka awm te, mut hmaa phone leh tablet hman tlem te hian a pui thei a ni.

Ruihhlo nena inzawmna (Drug Interactions) te

Ingrezza i ei a nih chuan damdawi dang i ei zawng zawng, vitamin pawh nise i doctor hnenah hrilh a pawimawh hle a , a chhan chu damdawi thenkhat hian Ingrezza nen hian an inzawm thei a ni.

• Monoamine oxidase inhibitor (MAOI) te hi a hnuaia mi ang hian a ni.Hengte hi depression emaw Parkinson’s disease emaw enkawlna atana hman thin damdawi te an ni. Heng MAOI damdawi te hi Ingrezza nena ei khap tlat a ni .
• Digoxin: Hei hi heart failure leh heartbeat mumal lo enkawlna atana hman thin damdawi a ni. Digoxin nena Ingrezza ei hian i thisenah Digoxin level a tisang thei a, side effect a thlen thei bawk. I doctor chuan i thisen a test ang a, a tul chuan Digoxin dose a tihhniam ang.
• CYP3A4 leh CYP2D6 inhibitors/inducers: Hengte hi damdawi lam thumal buaithlak deuh a ni. Damdawi chi hrang hrangah an hmang thin. I tih theih awlsam ber leh him ber chu i damdawi ei zawng zawng doctor hnenah hrilh vek hi a ni. A tul anga insiamremna a siam ang.