Huntington natna hi eng nge ni? A awlsam zawngin sawi ila.

I chhungkuaa mi tu emaw, i nu emaw, i pa emaw, i hriat mi emaw pawhin an taksa peng hrang hrang a thunun thei lo thut tih i hre ngai em? Thil chi hrang hrang, khur tenau te, a châng chuan tlu mai mai te, leia thil tlu te, a nih loh leh thinrimna leh lungngaihna ang chi rilru put hmang thunun harsa i neihte ang chi thilte chu i hmu tawh mai thei. Chûng thilte chu pâwn lamah chuan thil tê tê angin lang mah se, a chhan chu a châng chuan a pawi hle thei a ni. Vawiin hian natna chi khat, a lan chhuah dan ang chi, mahse kan rama mi tam takin an hriat ngai loh chungchang kan sawi dawn a ni. Chu chu Huntington-a Natna a ni.

A awlsam zawngin, Huntington’s Disease hi eng nge ni?

Huntington natna hi genetic condition a ni a, thluak, a bik takin nerve cells te a nghawng a ni . Thluak chhunga chetna leh hriatrengna thununtu peng hrang hrangte a nghawng a ni.

Kan taksa hi computer angin han ngaihtuah teh. Thluak hi a control center ber a ni. He natna hi a lo awm chuan chu control center-a program thenkhat chu a buai hle. Tichuan taksa chetna, rilru natna leh ngaihtuahna ang chi thilte chu a buai tan ta a ni. Hun a kal zel a, heng symptoms te hi a pung zauh zauh a, a tlahniam lo.

He natna hi a danglamna a awm em?

Ni e, Huntington natna hi chi hnih lian tak a awm a.

1. Puitling tan: Hei hi a tam ber chi a ni. Kum 30 an tlin hnuah symptoms hi a lang tan tlangpui.

2. Juvenile Huntington’s disease: Hei hi a chi hrang hrang a awm lo hle. Naupang leh tleirawl puitlingte a nghawng a ni.

Huntington natna lan chhuah dan chu engte nge ni?

He natna hian kan taksa bakah kan rilru a nghawng a ni. Chuvangin, a natna lan chhuah dan hi chi hnih lian takah then theih a ni. Hriatthiam awlsam zawk nan hetiang hian han thlir ila.

A tir lamah chuan heng symptoms te hi hriat tur a awm lo mai thei. Pen keng emaw, tlu emaw ang chi thil awlsam tak aṭangin an ṭan thei a ni. Mahse hun kal zelah heng symptoms te hi a na zual zel thei a, nitin hna chu mahni chauha thawh theih loh a ni.

Engvangin nge he natna hi a lo awm? A chhan chu eng nge ni?

Huntington natna thlentu ber chu genetic mutation a ni. A awlsam zawngin kan taksaa `HTT` an tih gene inthlak danglamna avanga lo awm a ni.

He `HTT` gene hian protein pakhat `huntingtin` tih a siam a. He protein hian kan thluaka nerve cell (neurons) te chu a thawk tha thei turin a pui thin.

Mahse, Huntington natna vei chuan `HTT` gene-ah chhiatna a neih avangin a siam chhuah `huntingtin` protein pawh a dik lo. Chu protein dik lo chuan nerve cell te chu a puih ai chuan a tichhe tan ta zawk a ni. Chutianga thluak cell te an thih chuan a hmaa kan sawi tak symptoms te chu a lo lang chhuak thin.

Hei hi thlahtu natna a ni em?

Awle. Hei hi thlahtu natna a ni ngei ang. Damdawi lamah chuan hei hi ``autosomal dominant`` pattern of inheritance kan ti a. Hei hian a awmzia chu:

A tlem hle a, mi tu emaw chuan an chhungkuaa tu pawhin he natna hi an nei lo a, chu chu genetic mutation thar vang a ni. Mahse chutiang chu a thleng tlem hle.

He natna hi engtin nge doctor hian a hriat theih ang?

Heng symptoms te hi i neih chuan doctor pan hmasak tur a ni. Ani chuan neurologist hnenah a refer mai thei che.

Natna hriat chian nan hian test eng emaw zat an nei thin.

• Taksa leh thluak enfiahna: Doctor chuan i taksa che vel, balance leh reflex te uluk takin a enfiah ang.
• Chhungkaw damdawi lam chanchin: I chhungte zingah he natna hi an vei tawh em tih zawhna i dawng ang. Hei hi a pawimawh hle.
• Genetic testing: Hei hi natna finfiah nan test pawimawh ber a ni. Hei hian i thisen sample lak a, a DNA-a HTT gene defect a awm leh awm loh test a huam a ni.
• Brain scan: Thluak ah hian danglamna a awm em tih hriat nan magnetic resonance imaging (MRI) leh computed tomography (CT) scan te pawh tih theih a ni bawk.

Symptoms a lan hmain hetiang hi i nei em tih hriat theih a ni em?

Ni e, i ti thei. I chhungkuaa mi (nu, pa, unaupa) chuan natna hi a vei a nih chuan, natna lan chhuah hmain nang pawhin gene hi i rochun em tih chu genetic test hmangin a hriat theih ang Hei hi ``predictive genetic testing'' an ti a.

Mahse hei hi thutlukna sensitive tak a ni.

• A thatna: Nakin lawkah he natna hi i vei thei tih hriatna hian chhungkaw ruahmanna leh sum leh pai ruahmannaah a pui thei che a ni.
• A that lohna: Tin, natna tihdam theih loh i nei tih hriat hi rilru lamah pawh a harsa hle thei bawk.

Hei hi enkawl dan tur a awm em?

Hei hi hriat tur lungchhiatthlak ber a ni. Tunah hian Huntington natna tidam kim thei tur emaw, natna lo awm tur titawp tur emaw, a natna lan chhuah dan tur titawp thei tur emaw damdawi a la awm lo.

Mahse, lungngai suh. Enkawlna tam tak a awm a, chu chuan natna lan chhuah dan a thunun thei a, damlo chu a nuam thei ang bera a nun theih nan a pui thei bawk.

• Physical therapy emaw occupational therapy: Heng enkawlnate hian taksa balance, muscle chakna leh nitin hna a awlsam zawk nan a pui thin.
• Thusawi hmanga enkawlna:Thusawi leh ei harsatnaah a pui thin.
• Counselling: Natna avanga lungngaihna leh lungngaihna ang chi dinhmunte hmachhawn tur chuan counselling hi a pawimawh hle.
• Damdawi: I natna lan chhuah dan control nan i doctor chuan damdawi chi hrang hrang a pe thei ang. Entir nan:
• Damdawi ``Tetrabenazine'' leh ``Deutetrabenazine'' te hi taksa khur (chorea) control nan an hmang thin.
• Depression leh rilru lama harsatna nei tan antidepressant leh antipsychotic damdawi ang chi damdawi te.

Engtin nge hun kal zelah natna hi a zual zel?

Huntington natna hi natna zual zel a ni a, a tlangpuiin stage thum kaltlangin a kal zel a ni.

He natna hian thihna a thlen thei em?

Huntington natna hian direct-in thihna a thlen lo. Amaherawhchu, he natna avanga harsatna awm chuan thihna a thlen thei a ni. Entir nan:

• Chaw ei harsat hian ei tur/in tur chu thawkna kawngah a tlakbuak thei a, pneumonia ang chi natna a thlen thei bawk.
• Tlu fo vanga hliam na tak tak .

He natna hi hmuhchhuah a nih atanga kum 10 atanga kum 30 inkar vel a ni tlangpui.I nung thei. He hun hi mi tin a inang lo.

Natna nena nung chungin eng nge i tih theih ang?

He natna hi pumpelh theih ni lo mah se, he natna nena nung reng chung hian nunphung tha tak vawng reng turin thil tam tak tih theih a awm.

• Exercise neih fo: Research atanga a lan dan chuan exercise hian taksa leh rilru hrisel taka awm theih nan a pui thei che a ni.
• Ei leh in tha tak nei rawh: Bodybuilding hian ni khatah calorie 5,000 thleng a hal thei. Chuvang chuan nutritionist rawn la, ei leh in tha tak ei a pawimawh.
• Tui in tam: Ei harsat hian tui tlakchhamna a thlen thei. Chuvang chuan nilengin tui mamawh zat in a pawimawh.
• Support group-ah tel ve rawh: He natna vei dangte leh an chhungte nena inbiakna neih hi rilru chakna petu ropui tak a ni.
• Nakin hun atana ruahmanna: I natna a zual chuan i mamawh tur enkawlna (home care services, nursing home) chu zirchiang lawk rawh. I sum leh pai leh dan lam thil enkawltu tur i rintlak mi ruat rawh.

He natna chungchang i hriat hian lungngaihna leh mangang taka awm hi thil pangngai a ni. Mahse, nangmah chauh i ni lo. Doctor, therapist, counselor leh i chhungte chu tanpui turin an awm reng a ni.