Mahni taksa thunun thei lo anga inhriatna hi engtiang chiahin nge tanpui theih loh? Ngaihtuah teh, i thusawi lai emaw, i ei lai emaw, document-a sign i tum lai emaw hian i hmai, i ke leh i taksa peng dangte chu thunun theih lohvin a inher leh a inher chhuak tan thin... Hei hi i nitin nun tibuaitu lian tak a ni a, khawtlang hmachhawn pawh i hlau thei hle. He thuziak ah hian chutiang thunun theih loh chetna tuar te tanpui thei damdawi kan sawi dawn a ni.
Heng chetna thunun loha awm chhan damdawi lam thil pahnih chu:
Damdawi Austedo hi natna pahnih enkawlna atan hman a ni ber. Eng nge an nih i han thlir teh ang.
1. Huntington natna vanga Chorea: Hei hi hming buaithlak tak angin ri mah se, a awlsam zawngin sawi ila, thlahtute atanga lo chhuak a ni. Hemiah hian thluaka nerve cell te chu zawi zawiin a chhe vek a. Hei hian ngaihtuahna, rilru put hmang thunun leh taksa chetna kawngah harsatna a thlen a ni. Hei hi thunun theih loh, rang tak, twitching, jerking movements chu chorea kan ti a ni.
2. Tardive Dyskinesia (TD): Hei hi taksa peng dang (mit, hmui), kut, ke leh taksa peng dang, thunun theih loha chetna (e.g., twitching, shaking) thlentu a ni bawk. Hei hi a chhan ber chu natna dang thenkhat, a bik takin antipsychotics atana hman damdawi te side effect a ni.
Austedo hian taksaah engtin nge hna a thawh?
Kan thluak hi message center lian tak ang mai a ni. Taksa chhunga taksa peng hrang hrangte hnenah thuchah a thawn a, chu chu "move" leh "stop" tih te hi nerve cells kaltlangin a ni. Heng thuchah kengtu chemical messenger te hi neurotransmitter an ti a .
Heng neurotransmitters te hi postmen angin han ngaihtuah teh. Thluak atanga ruh (muscle) thlengin lehkha (message) an phur a.
Chutiang key messenger pakhat chu Dopamine hi a ni. A chunga kan sawi tak Chorea leh Tardive Dyskinesia (TD) condition pahnihah hian heng dopamine ang chi messenger te hian message an thawn tam lutuk emaw, a dik lo emaw a ni. Hei hian a awmzia chu taksa ruhte hian "move, move" turin signal tul lo tak tak an dawng tam lutuk tihna a ni. Chuvang chuan taksa chu thunun theih lohvin a inher leh a inher tan thin.
Austedo hian a tih tur chu a tul lo taka message thawn chhuah zat control hi a ni. Chu chu, chu ‘traffic’ chu tlem a tihtlem bakah, a tul lo taka inthlak danglamna a tihtlem phah tihna a ni.
He damdawi hi engtin nge hman tur?
Austedo tablet hi chi hnih a awm a.
- Regular pill: I doctor chuan ni khatah vawi khat emaw vawi hnih emaw ei turin a rawt thei ang.
- Austedo XR: Hei hi ‘Extended-Release’ pill a ni. Chumi awmzia chu damdawi chu darkar engemaw zat chhung taksaah a chhuak tihna a ni. Chuvangin ni khatah vawi khat ei a ni tlangpui.
I doctor chuan dose hniam tak (starting dose) hmangin a tan tir ang che . Tichuan, kar tin, i symptoms control tha ber maintenance dose i hmuh hma loh chuan dose chu an tipung zauh zauh ang. Chuvang chuan doctor-in a sawi angin i dose siamrem a pawimawh hle.
Damdawi i ei dawnin hengte hi hre reng ang che:
- Austedo regular tablet hi chaw ei rualin ei tur a ni. Austedo XR tablet hi ei tur nen emaw ei loh pawhin ei theih a ni.
- Tablet chu tichhia suh, tikehsawm suh, chew suh. Tui glass khat nen a pumin ei rawh.
- Austedo XR i ei chuan tablet thenkhat, coating la awm ang bawkin damdawi chu a insiam kim vek hnuah i stool-ah a pass out tih i hmu mai thei. Hei hi thil pangngai a ni a, ngaihtuahawm tur a ni lo.
- Dose i miss a nih chuan i hriatreng veleh ei nghal rawh . Mahse, i dose leh tur hun a lo thleng tawh a nih chuan missed dose kha skip la, i dose lo awm tur chu a hun pangngaiah ei rawh. Dose vawi hnih ei loh chu vawi khatah ei ngai suh. I chiang lo a nih chuan doctor zawt rawh.
Engtin nge damdawi hian hna a thawk em tih i hriat theih ang?
Results beisei nghal a har khawp mai. I chetna thunun loh chu a reh theih nan kar tam tak atanga thla tam tak a la ngai thei. I doctor hian i tana dose dik tak a hmuh theih nan hun engemaw chen a la dawn avangin dawhtheih a pawimawh.
I natna lan chhuah dan a tha lo emaw, a zual zel ang tih emaw i hriat chuan i doctor nen inbia ngei ang che. I dose chu a thlak danglam thei a, enkawlna dang a ngaihtuah thei bawk.
Side effect awm thei leh engtin nge kan hmachhawn ang?
Damdawi dang ang bawkin Austedo hian mi thenkhatah side effect a nei thei a ni. Mahse, mi zawng zawngin an hmu vek lo. A hnuaia table-ah hian side effects awm tam zawk leh enkawl dan awlsam thenkhat tarlan a ni.
| Side Effect a awm thei | Engtin nge kan Manage ang? |
|---|---|
| Mut theih lohna, hahna | Damdawi hian engtin nge a nghawng che tih chiang taka i hriat hma loh chuan, lirthei khalh emaw, machinery hman emaw ang chi fimkhur ngai thil tih hi pumpelh rawh. |
| Kawthalo | Dehydration ven nan tui leh tui ang chi tui tam tak in tur a ni. Banana, buhfai, leh chhang ang chi ei tur ei thin ang che. A nasat chuan doctor hnenah hrilh rawh. |
| Kawng vawt | Tui tam tak in fo thin ang che. I hmui hmang lovin i hnar hmanga thawk chhuah tum ang che. Sugar tel lo gum chewing pawhin a pui thei bawk. |
| Buaina Mutnaah | Zan lamah coffee leh tea ang chi caffeinated in tur in loh tur. Mut hun bituk nei rawh. Mut hmaa i phone leh tablet hman tlem zawk rawh. |
| Hnar emaw, ril emaw natna (khawsik ang chi) . | Chungte chu ni engemaw zat chhungin a reh tlangpui. Tui lum in leh chawlh hahdam hian a pui thei a ni. Symptoms a nasat emaw, a awm reng emaw chuan doctor hnenah hrilh rawh. |
He damdawi nena inmil lo damdawi dang (Drug Interactions) .
Hei hi a pawimawh hle a ni. Austedo ei hian damdawi ei loh tur a awm a, chu chu fimkhur hle tur a ni.
Damdawi ei ngai loh tur: 1.1.
- MAOIs (Monoamine Oxidase Inhibitors): Hengte hi depression emaw Parkinson natna emaw damdawi chi khat pek thin a ni.
- Reserpine: Damdawi hlui, thisen sang nana hman thin a ni.
- Tetrabenazine leh Valbenazine: Hengte hi damdawi dang, chetna lama harsatna enkawlna atana hman thin, Austedo ang chi te pawh an ni. An ei dun hian side effect na tak a thlen theihna a tipung thei a ni.
Damdawi fimkhur taka ei tur: 1.1.
- CYP2D6 inhibitors: Hemi hi a buaithlak deuh. A awlsam zawngin sawi ila, Austedo hi antidepressant bupropion leh fluoxetine te nen emaw, heart rhythm damdawi quinidine ang chi te nen ei hian i thisenah Austedo level a tisang thei a, side effects i neih theihna a tipung thei bawk. Heng damdawi zinga pakhat i ei a nih chuan i doctor chuan Austedo dose a tihhniam thei a ni.
- Antipsychotics (rilru lam natna damdawi): Austedo nena ei hian hengte hian parkinsonism, taksa ruh (muscle stiffness) (neuroleptic malignant syndrome), leh restlessness (akathisia) ang chi natna a tipung thei a ni.
- Damdawi dang, mutthilh leh zu a thlen thei: Austedo hian mut a tichhuak thei. Chuvangin, Benadryl ang chi allergy damdawi emaw, mutthilh tir thei damdawi dang emaw nena ei chuan mut a tipung thei a ni. Austedo i ei lai hian zu in loh vek tur a ni.
Chuvangin, i damdawi ei zawng zawng (condition dang damdawi, vitamin, leh hnam damdawi thlengin) i doctor hnenah hriattir a pawimawh hle.
Take-Home Thuchah a ni
- Austedo hi damdawi bik a ni a, Huntington natna leh Tardive Dyskinesia (TD) vanga chetna thunun theih loh enkawlna atana hman a ni.
- He damdawi hi doctor thurawn ang chauha ei tur a ni. I doctor-in a tih ang chiah khan dose chu zawm rawh. Nangmah ngeiin dose thlak emaw, tihtawp emaw loh tur.
- Khawngaihin enkawlna hi dawhthei takin awm rawh u, a result hmuh nan kar emaw thla engemaw zat emaw a ngai thei a ni.
- Damdawi dang zawng zawng, vitamin leh supplement i ei tur zawng zawng doctor hnenah hriattir a pawimawh hle.
- Side effect na tak tak a awm a, symptoms a zual emaw, he damdawi hi harsatna i neih chuan doctor nen inbia nghal rawh.
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