I mitmeng pawh a tla chhuak em? Nunna nei lo niin i inhria em? Chu chu myasthenia gravis a ni em?

Zingkar i thawh hian a chang chuan i dam tha ang tih i inhria a, mahse ni a lo kal zel a, i taksa chuan chakna a hloh tan thin em? A bik takin i mitmeng a rit leh a tlahniam a, i thusawi laiin i thusawi a hrual a, a nih loh leh kut emaw, ke emaw pawh chawi harsa i tih hian? Hengte hi i hriat chian a nih chuan tunlaia kan sawi tur dinhmun, Myasthenia Gravis , a tawi zawngin MG tia koh hi i hriat a pawimawh hle.

A awlsam zawngin, Myasthenia Gravis chu eng nge ni?

Hei hi autoimmune disease a ni a, dam chhung zawng a daih thei a ni. A awlsam zawngin kan taksa invenna system, immune system hian kan taksa peng hrisel tak takte chu a rawn bei sual tan ta a ni. MG-ah chuan he attack hian kan nerve leh muscle inzawmnate chu a target a ni.

Ngaihtuah teh, kan thluak hian taksa peng pakhat hnenah, "Okay, tunah chuan i contract dawn a ni," a ti a. He thuchah hian nerve-ah a kal tur a ni a, taksa ruh (muscle) thlengin a thleng tur a ni. Mahse MG vei mi pakhatah chuan he thuchah phurhna "receptors" te hi anmahni immune system hian a tibuai thin. Phone call i tum chuan signal hloh ang mai a ni.

Chumi avang chuan taksa peng hrang hranga signal thawn te chu hman a nih rualin a chak lo zual a, zawi zawiin taksa pengte chuan an chakna an hloh zauh zauh thin. Mahse hun rei vak lo an chawlh hnuah an dinhmun pangngaiah an kir leh thin. Hei hi MG danglamna ber a ni. Hetiang dinhmun hi kum eng pawhah awm thei mahse, hmeichhia kum 40 hnuai lam leh mipa kum 60 chunglam ah a awm tam ber.

Engvangin nge kan taksa hian hetiang hian a tih? A chhan engte nge ni?

Engvangin nge immune system hian kan neuromuscular junction hi hetiang hian a beih tih chiang takin hriat a la ni lo. Mahse a chhan ber chu taksain neurotransmitter acetylcholine dawngtu receptor te lakah antibody a siam chhuak thin a ni. He acetylcholine hi "messenger" a ni a, chu chuan taksa ruhte chu a inzawm khawm tur thuchah a keng tel a ni. Chuvangin he messenger hnathawhna hmun hi a block chuan taksa ruhte hian hna a thawk tha lo.

Mi thenkhat chuan protein dang laka antibody an siam bawk. Hei hian genetic influence a nei thei nia ngaih ni mah se, MG vei tam tak chuan an chhungkuaah he natna vei dang an nei lo.

Tin, rilru chunglam chhunga taksa peng pakhat thymus gland , chu a inrawlh tih hmuhchhuah a ni bawk. He gland hi MG vei thenkhatah chuan a lian thin. Zirchiangtute chuan a chang chuan he gland hian taksa hi a hriattir dik lo va, heng antibody duh loh tak takte hi a siam chhuak thin niin an ngai.

Eng symptoms langsar ber berte nge hmuh theih?

MG natna lan chhuah dan hi mi hrang hrangah a inang lo. Mi thenkhat chuan symptoms an nei nghal mai thei. Mi dangte chuan zawi zawiin an tipung thei a ni. A natna hmunpui ber leh a natna lan chhuah dan te han thlir ila.

Engtin nge hei hi natna a ni tih chiang taka i hriat theih?

Heng symptoms te hi i neih chuan chhungkaw doctor pan hmasa phawt tur a ni. Hei hi a rinhlelh chuan neurologist hnenah a refer ang che. I natna lan chhuah dan a zawt ang che a, taksa enfiahna a nei ang che. Chu bakah, a natna hriat chian nan test engemaw zat tih theih a awm bawk:

• Thisen test: I thisenah khan kan sawi tawh ang chi antibody tha lo (acetylcholine receptor antibodies) te kha enfiah thin ang che.
• Edrophonium test: He test hian damdawi pakhatin hun engemaw chen i taksa ruh chakna a tipung em tih a enfiah thin. Chakna a lo pung nghal a nih chuan MG chhinchhiahna a ni thei.
• Neurostimulation tests: Muscle pakhatah needle te tak te dahin nerve signal tlan chak dan an teh thin. Hei hi taksa ruh pakhat chu hman nawn fo a nih chuan engtiang chiahin nge a chak lo tih hriat nan hman theih a ni (electromyography).
• Ice pack test: Ice pack chu mitmeng tla chungah minute engemaw zat dahin mitmeng chu a sang em tih en a ni. Hei hian natna chungchang ngaihtuahna a pe thei a, a chhan chu khawsik hian hun engemaw chen atan neuromuscular communication a titha a ni.
• Imaging: Diagnosis i hriat chian hnuah CT scan emaw MRI scan emaw hmangin i thymus gland-a harsatna awm leh awm loh enfiah theih a ni a, chu chu tumor (thymoma) ang chi hi a ni.

Eng enkawlna nge awm?

MG hi a dam kim theih loh, mahse hlawhtling taka enkawl theih a ni. I doctor chuan i natna lan chhuah dan nasat dan, i kum leh i hriselna zawng zawng a zirin i tan enkawlna tha ber a thlang ang.

1. Taksa tichaktu damdawi: Enkawlna hmasa ber chu pyridostigmine ang damdawi a ni. Hengte hian neuromuscular junction-a acetylcholine awm zat tihpunna hmangin hna an thawk a ni. He damdawi hian a ei atanga minute 15-30 chhungin chakna a pe a, darkar 3-4 vel a daih bawk.

2. Immune system suppressors: Mi tam takin heng damdawi te hi an mamawh a, a chhan chu he natna hi keimahni immune system atanga lo chhuak a nih vang a ni. A hmasain prednisone ang chi steroid pek a ni a, chutah chuan damdawi dang azathioprine ang chi chu thlak a ni. Hengte hian result a lantir nan thla engemaw zat a la ngai thei.

3. Thymectomy: Thymus gland-ah tumor a awm emaw awm lo emaw, surgery hmanga lakchhuah hian damlo thenkhatah symptoms nasa takin a ti tlem a ni.

4. IV Therapy hmanga enkawlna: 1.1.He enkawlna hi a natna lan chhuah dan a nasat em avangin pek thin a ni a, a nih loh leh myasthenia crisis ang chi a nih chuan pek thin a ni.

• Plasmapheresis: Machine bik hian i thisen atanga antibody tha lo tak tak te chu a paih chhuak a, plasma hrisel tak chu i taksaah a rawn thawn kir leh thin.
• IVIG therapy: Donor hrisel tak tak atanga lak antibodies (immunoglobulin) taksaah pek hian hun eng emaw chen atan immune system hnathawh a tidanglam thin.
• Monoclonal antibodies: Hengte hi laboratory-a siam specialized antibodies a ni a, immune system-a hmun bik, a thawk tha lote chu target-in a bei thin.

Engtin nge i in enkawl ang?

Damdawi lam enkawlna rual hian i nunphung inthlak danglamna tenau tak tak atang pawhin hahdamna nasa tak i hmu thei bawk.

• Ei leh in tha tak nei rawh: Chaw lian vawi khat ei ai chuan nitin chaw tenau engemaw zat ei thin ang che. I chaw ei ber chu chakna i neih tam ber hunah ei rawh. Chaw ei hmaa taksa ruh tichaktu damdawi ei chungchang doctor nen sawiho rawh.
• Exercise la, mahse i huam chin hre rawh: Exercise hian hun rei tak chhung chakna pe thei che mah se, thawhrim lutuk chu pumpelh rawh. I doctor emaw physical therapist emaw hnenah eng exercise nge i tan a tha tih zawt rawh.
• I chau nia i hriat hunah chawlh hahdam rawh: Nitin i tih thin chu chhunzawm zel ang che. Mahse, i chau tan meuh chuan chawlh hahdam la. I taksa chu ngaithla rawh.
• Natna thlentu hre rawh: Mi thenkhat chuan an damloh lai te, an stress lai te, hmeichhiate thlasik lai te, leh damdawi thenkhat avang te hian MG symptoms a pung thei a ni. Hemi chungchang hi i doctor nen sawiho rawh.