I ruhro (bone marrow) hian hna a thawk tha lo em ni? Myelosuppression chungchang hi han sawi ila!

I dam lo mai mai emaw, i damlo reng emaw, cancer enkawlna emaw, natna dang emaw i neih pawhin, hliam tlemte pawh atanga thisen chhuak ang maiin i inhria bawk em? Heng thilte hnuaiah hian myelosuppression , ruhro (bone marrow) a thawk tha lo tihna a awm thei a ni. Ngaihtuah buai suh, he thu hi awlsam takin sawi ila.

Myelosuppression chu eng nge ni? A dik tak chuan ruhro chak lohna a ni em?

A awlsam zawngin, a ni! Bone marrow chu i ruh chhunga tissue nem tak, spongy ang maia awm a ni. Kan taksa thisen siamna factory angin han ngaihtuah teh . He factory hian kan dam khawchhuahna atana pawimawh tak, thisen sen, thisen var leh platelet maktaduai tam tak a siam chhuak a, kan thisenah a belhchhah a ni. Cell chi tin hian kan taksa tan hna hrang hrang an nei a. Kan taksa mamawh dan azirin bone marrow hian he production hi a tipung emaw a ti tlem emaw a ni.

Tunah chuan myelosuppression tih dinhmunah hian he bone marrow factory hnathawh hi eng emaw chhan vangin a buai ta a ni. Tichuan, thisen cell leh platelet te chu mumal taka siam chhuah theih a ni lo. Hei hi a chhan ber chu cancer enkawlna chemotherapy a ni. Amaherawhchu, thisen cancer chi thenkhat leh virus thenkhat te hian ruhro (bone marrow failure) a thlen thei bawk.

Myelosuppression natna lan chhuah dan chu engte nge ni?

Mi tin a natna lan chhuah dan chu a inang lo thei a, chu chu i ruhro hian thisen sen, thisen var, a nih loh leh platelet a siam chhuah dan azirin a inang lo thei a ni.

Thisen sen a tlahniam chuan - Anemia

Thisen sen (red blood cells) hian i taksa pum puiah oxygen a keng tel a . An tlem chuan , thisen tlakchhamna (anemia) a lo awm thin. A lan chhuah dan chu:

• Chau
• Thâwk hah / thawk hah
• Luak chhuak thei
• Thinlung thawk chak emaw, mumal lo emaw / arrhythmia
• Beng chhunga ring ri ri hriatna, a chang chuan "thumping" ri leh thinlung thawk (Pulsatile tinnitus) .
• Lu na
• Vun rawng a paleness
• A rilru a na

Neutropenia - thisen var (a bik takin neutrophils) tlahniam .

Thisen var hian kan taksaa lut hrik te chu a do a , natna hrik lakah min venghim . Thisen var chi khat chu neutrophils an ti a . Myelosuppression avanga ruhroin neutrophils a siam tlem chuan chu natna chu neutropenia an ti a ni. Neutropenia hian symptom bik a nei lo a, mahse hei vang hian a niInfection hi a awm fo thei a, chutih lai chuan symptoms a lo lang thin.

• Khawsik (a then phei chuan febrile neutropenia an ti bawk ) .
• Chau lutuk
• Thlarau na/infection (Thlarau na/pharyngitis) .
• Lymph node a lo hring chhuak
• Kawngkhar emaw, hnute chhehvel emawa ulcer awm
• Kawthalo
• Zun laia kang, zun vat ngai anga inhria, zun fo thin

Platelets a tlahniam chuan - Thrombocytopenia

Platelets hian thisen chhuah control nan a pui thin . Heng level te hi a tlahniam chuan thrombocytopenia an tih natna a lo awm thin. Hei hian hetiang hian a thlen thei:

• Hun rei tak chhung thisen chhuak lo, hliam tenau atanga lo chhuak emaw, hnar thisen chhuak tihtawp harsat emaw.
• Bruise hi a tlangpui aia rang zawkin a lang.
• Ke hnuai lam atanga rawng sen te te (rash ang chi) lo lang - hei hi petechiae an ti a.
• Vunah hian a sen, a sen emaw, a sen emaw a awm - hei hi purpura an ti a.

Thisen cell chi hrang hrang a tlahniam vek chuan - Pancytopenia

A châng chuan, chûng thisen cell pathum—thisen sen, thisen var, leh platelet—te chu a rualin a hniam thei vek a ni . Hetiang dinhmun hi pancytopenia an ti a . Neutropenia ang bawkin hei hi a takin natna a ni lo va, mahse a hnuaia damdawi lam dinhmun chhinchhiahna a ni thei.

Engvangin nge myelosuppression hi a lo awm? A chhante chu engte nge ni?

Kan sawi tawh ang khan chemotherapy hi a chhan ber a ni . Mahse, a chhan dang pawh a awm bawk.

Chemotherapy, immunotherapy, leh myelosuppression te a ni

Chemotherapy damdawi chi hrang hrang hian hetiang hi a thlen thei a ni. A tlangpuiin thenkhat chu:

• Fluorouracil hmanga siam a ni
• Oxaliplatin a ni
• Irinotecan a ni
• Capecitabine hman a ni

Tin, CAR T-cell therapy, immunotherapy chi khat , hian ruhro hnathawh a tichhe thei bawk a, thisen cell leh platelet siam chhuah a ti tlem thei bawk.

Thisen Cancer leh Myelosuppression te hi a ni

Thisen cancer thenkhat hian thisen cell siam dan pangngai a tibuai thei bawk. Entîr nân, cancer , leukemia, lymphoma, leh myeloma -ah te chuan ruhroah cancer cell pangngai lote chu an lo thang lian lutuk a, thisen cell hrisel leh platelet siam chhuah chu a titawp a ni.

Virus leh myelosuppression te a awm bawk

Viral infection thenkhat chuan ruhro (bone marrow)-a thisen siam dan pawh a tibuai thei bawk. Virus taksaa a luh chuan kan taksa invenna, thisen var (white blood cells) te hian virus hi an do thin tih han ngaihtuah teh. He insual chhung hian ruhro hian thisen sen leh platelet tlemte a siam thei a ni. Zirchianna thenkhatah chuan virus thenkhat chuan ruhro chhunga thisen siamtu cell te chu direct-in an kai a, thisen cell zat a tihtlem phah a ni. Hetiang myelosuppression natna nena inzawm nia hriat virus thenkhat chu:

• Epstein-Barr hrik (EBV) hrik pai a ni.
• Hepatitis C natna hrik a ni
• Parvovirus B19 a awm bawk
• Cytomegalovirus (CMV) natna hrik pai a ni.
• Vawk natna thlentu virus (Chickenpox / varicella zoster) .
• Mihring taksa chak lohna hrik (HIV) .
• Dengue natna a ni

Myelosuppression hian harsatna lian tak a thlen thei em?

Ni e, a châng chuan hei hian nunna atana hlauhawm harsatna a thlen thei . Entirnan, thisen sen tlahniam nghal (acute anemia) emaw, platelet tlahniam (thisen chhuah thunun theih loh) emaw .

Pawimawh: Heng symptoms zinga pakhat tal i neih chuan, a bik takin cancer enkawl mek i nih chuan doctor thurawn lak nghal a pawimawh hle.

Engtin nge doctor-te hian he natna hi dik taka an hriat theih?

Hei hi thisen test hmanga hriat chhuah a ni ber . Heng thisen test te hian i ruhro hian thisen cell leh platelet a siam chhuak pangngai em tih a enfiah thin.

Hetiang thisen test hi tih theih a ni:

• Thisen chhiar kim (CBC) 1.1.
• MCV test (Mean corpuscular volume / MCV test) hmanga enfiah a ni.
• RDW test (Red cell sem zau zawng / RDW test) hmanga enfiah a ni.
• Reticulocyte chhiar chhuah a ni
• Peripheral thisen hmanga hnawih
• MPV test (Platelet volume mean / MPV test) hmanga enfiah a ni.

Myelosuppression hi eng enkawlna nge ni?

Doctor-te chuan hetiang hian an enkawl a:

• Myelosuppression awm chhan chu chemotherapy a nih chuan chemotherapy dose hi tihtlem emaw, rei lo te chhung tihtawp emaw a ngai a ni .
• Thisen pek hi thisen sen leh platelet level tihsan nan a ni.
• I ruhro thisen cell leh platelet tam zawk siam tura pui thei damdawi pek che .

Hetiang dinhmun hi a lo thlen loh nan ven theih a ni em?

Myelosuppression hi cancer enkawlna avanga side effect angin a awm fo thin. Chuvangin, cancer enkawl lai hian doctor-te chuan heng side effects te hi an lo thlir reng a ni . I thisen test te an enfiah fo ang a, a tul chuan i treatment plan pawh an thlak danglam ang.

Myelosuppression ka neih chuan eng nge ka beisei theih ang?

Mi tam tak chuan he natna hi an vei chhan chu chemotherapy an lak vang a ni. Chutiang a nih chuan i doctor chuan chemotherapy hian i ruhro a nghawng dan chu uluk takin a enfiah ang . I ruhro hian a thisen cell count a siam that theih nan cancer enkawlna atanga chawlh rei vak lo i lak a ngai mai thei.

Engtin nge ka in enkawl ang?

Myelosuppression hian natna hrik vei leh thisen chhuah theihna a tipung thei a ni . He hlauhawmna tihtlem nan hian heng thilte hi i ti thei ang:

• Virus tlanglawn laka invenna tur vaccine lak thin ang che .
• Practicing good hygiene habits , kut sil fo leh damlote laka inthiarfihlim ang chi te.
• I hliam emaw i hliam emaw theihna tur dinhmun lakah inveng rawh . Entirnan, ralthuam hriam tak i hman hunah fimkhur hle ang che.

Doctor hnenah eng zawhna nge ka zawh ang?

Doctor hnenah zawhna hetiang hi i zawt thei ang:

• Engvangin nge he myelosuppression condition hi ka neih?
• He dinhmun hian engtin nge ka taksa a nghawng?
• Eng enkawlna kawng nge ka neih?
• Treatment hian ka myelosuppression hi a tidam vek dawn em ni?

Thupui: Hriat reng tur (Take-Home Message) .

I ruhro hi i taksa peng pawimawh tak a ni. Oxygen kengtu thisen sen, natna hrik dotu thisen var, i thisen zam tura puitu platelet – chutah chuan siam vek an ni. Myelosuppression chu eng emaw vanga i ruhro hnathawh a chawlhsan chuan a ni. A chhan langsar ber chu cancer natna chemotherapy a ni a, mahse thisen cancer leh virus thenkhat vang pawh a ni thei. Lungngai suh. Doctor ten a chhan zawngin an enkawl ang. A pawimawh ber chu natna lan chhuah dan danglam tak i neih chuan damdawi lam pan a, an thurawn uluk taka zawm hi a ni. Nangmah chauh i ni lo va, he zinkawng zawh tura pui theitu doctor an awm bawk.

` Myelosuppression, Bone Marrow Suppression, Bone Marrow, Red Blood Cells, White Blood Cells, Platelets, Chemotherapy, Cancer, Thisen tlakchhamna, Neutropenia, Thrombocytopenia, Infection