Cancer do hi thil awlsam a ni lo tih kan hre vek. He indonaah hian i doctor-te chuan enkawlna chi hrang hrang, chemotherapy ang chi te an rawt ang. Pegaspargase (brand name: Oncaspar) hi damdawi pawimawh leh chak ber pakhat a ni a, thisen cancer chi khat acute lymphoblastic leukemia (ALL) tih enkawlna atana hman a ni. Chuvangin, nangmah emaw, i hmangaih tak emaw hnenah he damdawi hi pek i nih chuan, a chungchang zawng zawng hriatthiam awlsam leh chiang tak i neih chuan i tan thlamuanna nasa tak a ni ang. Hemi chungchang hi han sawi ila.
Pegaspargase hi eng damdawi nge ni?
A awlsam zawngin, Pegaspargase hi chemotherapy damdawi a ni a, chu chu cancer cell tihhlumna atana pek damdawi a ni . Asparagine hi cancer cells te thanlenna atana nutrient pawimawh tak a ni. Pegaspargase hian a tih chu taksaa he asparagine nutrient hi a tichhia a, cancer cell te chu "chaw" a hloh tir a ni. Tichuan cancer cell te chu an thang thei lo va, an thi ta a ni.
Acute Lymphoblastic Leukemia (ALL) enkawlna atana hman ber ni mah se, a chang chuan doctor-in a rawt angin cancer chi dang tan pawh hman theih a ni.
Enkawlna i tan hmaa i doctor hnena i hrilh tur thilte
He enkawlna hi i tan hmain i doctor hnenah i hriselna chanchin kimchang hrilh hmasak a pawimawh hle . He damdawi hian hriselna lama harsatna thenkhat nen a inzawm thei a ni. A bik takin heng thilte hi i doctor hnenah hrilh ngei ang che:
- Allergy: Pegaspargase, L-asparaginase, E. coli proteins, damdawi dang, ei tur emaw, dye emaw allergy i neih chuan min hrilh ngei ang che.
- Pancreatitis: Pancreatitis i lo vei tawh a nih chuan.
- Liver disease: Liver natna chi hrang hrang i neih chuan.
- Thisen zam harsatna: I thisen a zam awlsam a nih chuan emaw, thisen chhuahna lama harsatna i neih chuan.
- Diabetes: Zunthlum emaw, thisen sugar level nena inzawm harsatna dang emaw i neih chuan.
- Naupai: Naupai, nau pai tum emaw, nau hnute pek emaw i nih chuan doctor hrilh a pawimawh. Hei hi a pawimawh hle.
I doctor hnenah damdawi dang i ei zawng zawng list kimchang pe la, vitamin, hnam damdawi leh supplement te pawh tiamin.
Engtin nge he damdawi hi taksaah pek a nih?
Hei hi in lama i hruai theih tur pill a ni lo. Damdawi inah emaw, damdawi inah emaw pek thin a ni., hemi chungchanga zirtirna bik dawng doctor emaw nursing staff emaw chauhvin an siam a ni.
Damdawi pek dan kawng hnih a awm a, chungte chu:
1. Intravenous infusion: Damdawi , saline ang chi chu zawi zawiin taksaah vein hmangin a lut a.
2. Intramuscular injection: Muscle chhunga injection a ni.
Hei hi naupang tê tê, thla khat mi lek pawh ni se, dinhmun thlan bik ṭhenkhatah pêk a ni. Mahse, thutlukna chu naupang enkawltu doctor-in a siam a ni.
Enkawlna kan neih hunah eng thilte nge ngaihtuah tur?
He damdawi i ei lai hian i doctor chuan uluk takin a lo en reng ang che.
- Thisen test: Damdawi hian i taksa a nghawng dan hriat nan thisen test neih fo a ngai dawn a ni.
- Thisen thlum: He damdawi hian thisen thlum a tisang thei. Zunthlum i vei a nih chuan i doctor hnenah ei leh in chungchang leh zunthlum damdawi i thlak a ngai em tih te sawipui ang che.
- Allergy: A chang chuan he damdawi hi allergy na tak a awm thei. Hetiang hlauhawmna tihziaawm nan hian i doctor chuan Pegaspargase a pek hmain damdawi dang (e.g. antihistamines, steroids) pek che a rel thei ang.
- Naupai leh hnute pek (CRITICAL): Hei hi a pawimawh hle.
- He damdawi ei lai hian eng vangin naupai suh **.
- Enkawlna chawlhsan hnuah thla 3 tal naupai loh tur a ni.
- Hemi hun chhung hian birth control i hmang ngei tur a ni. Mahse, hormonal birth control pills (oral contraceptives) hian he damdawi nen hian a inzawm thei a, chuvangin hormonal ni lo naupai venna (e.g. condom) hman chungchang hi doctor nen sawiho rawh.
- Naupai tih rinhlelhna tlemte pawh i neih chuan i doctor hnenah hrilh nghal rawh .
- I naute chu enkawl lai leh chawlhsan hnu thla khat chhung chu hnute pe suh.
Damdawi avanga side effect lo awm thei
Damdawi dang ang bawkin Pegaspargase hian side effect a nei thei a ni. Mi zawng zawngin an hmu vek lo. Mahse, heng symptoms te hi hriat chian a pawimawh hle. Symptom na tak i hmuh chuan medical staff te hriattir nghal emaw, Emergency Department (ETU) hnai ber pan emaw .
| Side effect category ah hian a awm thei | Features fimkhur tur a awm |
|---|---|
| I doctor emaw damdawi ina thawktute hnena hrilh nghal tur thil | |
| Allergic Reaction na tak tak a awm thei | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring, thawk harsa. |
| Thisen chhuahna symptoms a awm | Thinrim dum, tarry tak tak; zun sen emaw, dum emaw; coffee ground ang maia lang emaw, thisen chhuak emaw; vunah a sen hring a awm a; mit, hmui, hnar atanga thisen chhuak danglam tak. |
| Thisen zam (Blood Clot) a lan chhuah dan | A rilru a na a; thawk harsa; ke na, a hring emaw, a lum emaw. |
| Liver chhiatna chhinchhiahna | Dark yellow emaw brown emaw zun; mit emaw vun emaw a sen (yellowing); khawsik; chaw ei chakna hloh; pum dinglam chunglam natna; pale stools a awm. |
| Thisen sugar sang chhinchhiahna | Tuihalna leh riltamna danglam tak; zun chhuah fo; hahna nasa lutuk; mit hmuhna (blurred vision). |
| Symptom na tak dang a awm bawk | Lu na nasa tak, pum na tak (pancreatitis chhinchhiahna a ni thei). |
| A awm reng emaw, a buaithlak emaw chuan doctor hnenah hrilh rawh. | |
| Side effect awm fo thin | Thawmhnaw hak, taksa rihna tlahniam. |
Damdawi dangah harsatna a awm thei em? (Inbiakpawhna) .
Awle. Damdawi thenkhat chu Pegaspargase nena ei hian harsatna a thlen thei. Entir nan:
- methotrexate hmanga siam a ni
- vincristine a ni
- cytarabine hmanga siam a ni
- dexamethasone a ni
- Naupai venna damdawi (oral contraceptives) .
He list hi a kim lo. Chuvangin, i damdawi i ei zawng zawng, vitamin pawh nise, i doctor hnenah hrilh rawh . Tin, zu i in emaw, zu i in emaw pawh hrilh theihnghilh suh ang che.
Take-Home Thuchah a ni
- Pegaspargase hi chemotherapy damdawi chak tak a ni a, thisen cancer chi khat Acute Lymphoblastic Leukemia (ALL) tih enkawlna atana hman a ni.
- He damdawi hi damdawi inah chauh pek a ni a, damdawi lam enkawlna hnuaiah pek a ni.
- Enkawlna i tan hmain i damdawi lam dinhmun zawng zawng, allergy leh damdawi dang i ei zawng zawngte chu i doctor hnenah hrilh hmasa phawt ang che.
- Allergy na tak, thisen chhuah, thisen zam, pum na nasa tak ang chi symptoms i neih chuan medical staff te hriattir nghal rawh.
- Enkawl lai leh a hnu thla 3 chhung chu naupai loh vek tur a ni. Naupai venna atana hmanraw rintlak, hormone tel lo hmang rawh.
- I enkawlna hun ruat saah a hun takah lo kal turin kan ngen a che u. I kal thei lo a nih chuan damdawi inah hriattir hmasak phawt tur a ni.
- He damdawi chungchanga zawhna emaw, ngaihtuahna emaw i neih chuan i doctor nen inhawng takin sawi rawh.
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