Kan taksaa thisen var (white blood cells) te hi natna laka min vengtu sipai ang a ni tih kan hre vek. Mahse, han ngaihtuah teh, heng venhimna cell, histiocyte tia koh te hi kan taksaah hian an lo thang lian lutuk a nih chuan eng nge thleng ang? Chutah chuan buaina chu a intan ta a ni. Heng cell te hi an khawlkhawm a, taksa hmun hrang hrangah tumor leh lesion an siam thei a ni. Vawiin hian natna rare tak, hetianga lo awm thin chungchang kan sawi dawn a ni.
LCH (Langerhans cell histiocytosis) tih hi eng nge ni?
A awlsam zawngin sawi ila, LCH (Langerhans Cell Histiocytosis) hi cancer chi thenkhat nen a inang lo hle. Hetiang dinhmunah hian immune cell chi khat Langerhans an tih chu thunun theih lohvin a thang lian a, taksa hmun hrang hrangah a pungkhawm thin.
He natna hi naupang te leh naute zingah a tam ber a , mahse puitlingah pawh a awm thei bawk. A châng chuan cancer nia ngaih ni mah se, a takah chuan cancer a ni lo. Mahse, oncologist ten an enkawl a ni. Chuvangin lungngai suh. Hei hi han en leh ila.
He natna lan chhuah dan engte nge ni?
LCH hian taksa peng eng pawh a nghawng thei a ni. Entirnan, lung, thin, thluak, ril, a nih loh leh lymph node te a nghawng thei a ni. Mahse, a lan chhuah tam ber chu vun leh ruh lamah a ni.
Mi thenkhat chuan symptoms na lo tak tak an nei thei a, enkawlna engmah awm lovin anmahni chauhin an dam thei bawk. Mahse, mi dangte tan chuan taksa peng hrang hrang tichhe thei, hun rei tak chhunga awm thei a ni.
LCH hian taksa peng hrang hrang a nghawng hian eng symptom nge a neih tih hriat nan a hnuaia table hi han en ila.
| Taksa peng a nghawng | Symptoms hmuh theih a awm |
|---|---|
| Ruh te | Vawi tam tak chu luruh leh ruh dangteah hian na tak tak emaw, lump (granulomas) emaw a lo awm thin. Hei hian ruh na a thlen thei a, a hring thei a, a chang chuan ke ruhte pawh a tikehsawm thei bawk. |
| Vun | Vun hrual (e.g. armpits, groin)-ah hian a sen, a hring (scaly bumps) a awm. Naute chuan lu vunah sen, hnah hring (scaly patches) an nei thei. Hei hi cradle cap tia ngaih sual theih a ni a, hei hi thil awm dan tlangpui a ni. |
| Thin | He natna khirh tak takah chuan thin (liver) hi a nghawng tlangpui. A lan chhuah dan chu vun sen (jaundice) leh thisen zam tihkhawtlai te a ni. |
| Lymph Nodes (Lymph Nodes) te a awm | Beng hnunglam, kawr leh hmun dangah te glands a hring chhuak. Tin, thawk harsa leh khuh a awm thei bawk. |
Engtin nge natna hi dik taka kan hriat theih ang?
I doctor-in he natna hi a rinhlelh chuan biopsy an tih a ngai dawn a, chu chuan a natna hi a finfiah a ngai dawn a ni. Hei hian rinhlelh awmna hmun atanga tissue te tak te tak tak lak a, microscope hmanga pathologist te enfiah tir a huam a ni. Hei hian protein bik leh natna bik atana marker dang a zawng ang.
Chu bakah, i doctor chuan i natna lan chhuah dan azirin test dang neih belh turin a ti thei bawk.
- X-ray test: I lung leh ruh dinhmun enfiah thin ang che.
- Bone marrow biopsy: Ruh chhunga LCH cell awm leh awm loh enfiah thin.
- Thisen chemistry test: Kal, thin, thyroid gland leh immune system te hnathawh dan enfiah thin.
- MRI, PET, leh CT scan: Taksa chhung lam chipchiar taka thlalak lak.
- Urinalysis: Zun chhunga red leh white cell, protein, leh sugar awm zat enfiah thin ang che.
Eng thilin nge LCH hi a thlen?
Mi thenkhatin LCH an vei chhan chiah kan la hre lo. Mahse he natna vei zinga a chanve vel hian gene dik lo an nei tih hmuhchhuah a ni a, chu chuan Langerhans cell te chu thunun theih lohvin a tipung a ni. Pawimawh tak chu he genetic change (mutation) hi pian hnuah a thleng thin. Hei hian nu leh pa atanga rochun natna a ni lo tihna a ni .
Chu bâkah, zirchiangtute chuan thil dang engemaw zât chuan hei hi a nghawng thei niin an ring bawk:
- Meizial zuk.
- Nu leh pate’n boruak tha lo, benzene emaw thing leivut emaw an tawrh thin.
- Nau piang thar hun chhunga hri kai.
- Chhungkaw history-a thyroid natna nei tawh.
Hei hi eng enkawlna nge ni?
Chemotherapy hi a chang chuan LCH enkawl nan an hmang thin a, cancer chi thenkhat enkawl nan an hman thin angin. Chuvangin he natna vei tam tak hi oncologist leh hematologist ten an enkawl a ni.
Mahse hre reng ang che, cancer ang lo takin LCH chi hrang hrang hi a chang chuan enkawlna engmah awm lovin a mah chauhin a reh thin.
A hnuaia table-ah hian enkawl dan tur eng nge awm tih i lo en ang u.
| Enkawl dan tur | A sawifiahna awlsam tak |
|---|---|
| Chemotherapy hmanga enkawl a ni | Natna cell tichhe thei damdawi pek. |
| Radiation hmanga enkawlna a ni | Low-dose radiation hi natnain a nghawng taksa peng hrang hrangah chauh pek a ni. |
| Inzai | LCH avanga tumor emaw lesion emaw surgery hmanga lakchhuah. |
| Steroids te pawh a awm | Steroid emaw anti-inflammatory damdawi dang prednisone emaw pek. |
| UV light hmanga enkawl a ni | Skin bik hmanga vun natna enkawlna. |
| Stem cell thlak danglam a ni | Case na tak takah chuan enkawl dan tur ngaihtuah thin. |
LCH vei tam zawk chu enkawl hnuah an dam leh thin. Natna hian i ril, i thin, i ruhro a nghawng a nih chuan ‘high-risk LCH’ an ti. Hetiang hunah pawh hian mi 80% vel chuan an dam kim vek a ni . Chuvangin beiseina nei reng a pawimawh.
Take-Home Thuchah a ni
- LCH hi natna hmuh tur awm lo tak a ni. Cancer tak tak a ni lo va, cancer ang bawka enkawl a ni.
- Hei hi naupang tê têah hmuh tam ber ni mah se, kum eng pawhah a lo awm thei a ni.
- Vun natna, ruh na, a hring ang chi symptom i neih chuan ngaihthah suh.
- Nang emaw i fa emaw hian heng natna lan chhuahna chungchangah hian rinhlelhna i neih chuan i doctor hmu ngei ang . Hlauthawng suh la, online-ah i diagnose tum ang che.
- Enkawlna dik tak an neih chuan LCH vei tam zawk chu an dam kim vek a ni. Chuvangin damdawi lam thurawn dik tak zawm a pawimawh hle.
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