I taksa hian Parathyroid Hormone hi a chhang tha lo em ni? He dinhmun mak tak (Pseudohypoparathyroidism) chungchang hi han sawi ila!

I taksaa thil pakhatin hna a thawk tha lo ang maiin a chang chuan i inhria em? Natna mak tak tak a awm a, a hming pawh a hlauhawm deuh thei. Chutiang natna pakhat, hriat hlawh lo, mahse hriat tur pawimawh tak chu Pseudohypoparathyroidism (PHP) hi a ni. A hming hi sei deuhin lang mahse, a awlsam zawngin i dah ang u.

Pseudohypoparathyroidism tih hi eng nge ni?

A awlsam zawngin, hei hi genetic condition hmuh tur awm lo tak a ni . Kan taksaah hian gland te tak te kan nei a, chu chu parathyroid glands an ti a. Chungte chuan hormone pakhat Parathyroid Hormone (PTH) an siam chhuak a. He PTH hormone hi kan taksa tan a pawimawh hle. A chhan chu, he hormone hian kan thisenah Calcium, Phosphorus, leh Vitamin D level dik tak a awm reng theih nan a pui a ni.

Tunah chuan, pseudohypoparathyroidism (PHP) vei chungah eng nge thleng tih i hria em? An parathyroid glands te hian PTH hormone hi a pangngaiin siam mahse an taksa chhunga cell te hian an chhang tha lo a, chu chu an "hriat" thei lo tihna a ni. Miin biak che mahse i hre thei lo ang mai a ni. Hei hi Parathyroid Hormone Resistance kan ti a .

Chumi avang chuan eng nge thleng? Thisen a calcium level a tlahniam a, phosphorus level a sang thung. Hetianga inthlauhna hian taksa ruh a ti na thei a, a ti na thei a, a rilru a buai thei a, ha a ti buai thei bawk.

Pawimawh tak chu he PHP an tih hi Hypoparathyroidism an tih nen hian a danglam a ni. Hypoparathyroidism vei te hian a tir lamah PTH hormone an siam tling lo. Amaherawhchu PHP-ah chuan hormone hi siam chhuah a ni a, taksain a hmang lo.

PHP chi hrang hrang lian ber berte chu engte nge ni?

PHP status hi chi hrang hrang lian tak tak a awm a. Eng nge an nih i en ang u.

PHP-1 type a ni

Hei hi PHP chi khat hman tlanglawn ber a ni . A hmaa kan sawi tawh PTH hormone resistance bakah hian skeletal system inthlak danglamna thenkhat hmuh tur a awm bawk. Entir nan:

• Hmai roundness a ni
• A san zawng tlahniam (a san zawng tawi) .
• Kawng a na
• Kut leh ke ruh tliak

Doctor-te chuan he natna lan chhuahna inzawmkhawm hi Albright Hereditary Osteodystrophy (AHO) tiin an sawi a. PHP-1 vei te hian an nu leh pa pakhat hnen atanga an rochun `GNAS` tih gene variant avang hian he natna hi an nei thin.

PPHP (Pseudopseudohypoparathyroidism) tih hi a tha hle a, a rilru a buai em em bawk a.

Hei hi PHP-1 form limited tak a ni. PPHP (Pseudopseudohypoparathyroidism) vei te hian AHO-a hmuh theih taksa pianphung (hmêl zung leh sei tawi ang chi) an nei thei a, mahse PTH hormone resistance an nei lo Chumi awmzia chu an calcium leh phosphorus level a normal tihna a ni.

PHP-2 type a ni

PHP-2 vei te hian PTH hormone resistance an nei a, chu chu calcium tlem leh phosphorus sang an nei tihna a ni. Mahse AHO-a hmuh ang taksa pianphung (hmêl zung leh sei tawi ang chi) an nei lo. Researcher te chuan eng genetic defect nge he PHP-2 chi hi a thlen tih chiang takin an la hre chiang lo.

PHP natna lanchhuahna chu engte nge ni?

PHP symptoms hi mi hrang hrangah a inang lo thei . Chumi awmzia chu mi zawng zawngin symptom inang an nei vek dawn lo tihna a ni. A lan chhuah dan tlangpui thenkhat chu:

• Muscle spasms a awm thin
• Frequent muscle cramps : Ke pakhat hrual ang maia hriatna.
• Ke ruh leh ke ruh (limbs) emaw, tingling emaw
• Seizures a awm thin
• Ha chhuah hun sawn hlat
• Ha enamel chak lohna
• Thisen sang hniam
• Sam leh nail brittle
• Hlauhthawnna
• Lungngaihna

PHP-1 vei te hian a hmaa kan sawi tawh Albright hereditary osteodystrophy (AHO) condition nen hian symptom dang an nei thei bawk. PHP vei thenkhat chuan heng symptoms te hi an nei ve thei bawk:

• Hmai roundness a ni
• Short stature (stature tawi) 1.1.
• Kawng a na
• Kut leh ke ruh : Kut zungtang, a bik takin kut zungtang palina leh pangana te chu chhung lam hawiin a lang thei.
• Obesity : Thau lutuk tihna a ni.
• Mitdelna : mitdel, mitdelna, leh êng laka invenna ang chi thil.
• I vun hnuaiah ruh bumps a awm
• Hmasawnna tlai : Naupang thenkhat chuan hmasawnna tihkhawtlai engemaw zat an tawk thei.

PHP awm chhante chu engte nge ni?

He natna thlentu ber chu kan genes a danglamna a ni a, a bik takin `GNAS` an tih gene ah hian a danglamna a ni . Mi thenkhat chuan an nu leh pa hnen atangin an rochun thin . Chu chu rochun a ni tihna a ni. Mahse a chang chuan he dinhmun hi chhungkaw history nei lovin a awm thei a, a chhan pawh hmuh tur a awm lo.

PHP hi nausen lai emaw, naupan lai emaw atanga hmuhchhuah a ni tlangpui a , mahse puitlingah pawh a lo lang thei bawk.

PHP avanga harsatna awm thei te chu engte nge ni?

PHP i neih chuan endocrine system disorder dang i nei tam zawk . Heng hormone nena inzawm harsatna te hian chakna tlahniam leh sex drive hniam ang chi symptoms a thlen thei a ni.

PHP vei thenkhat chu hetiang dinhmun hi an vei theihna chance a sang zawk a ni:

• Parkinson natna vei a ni: Parkinson natna ang chi symptoms nei.
• Fine motor skills lama harsatna : Hei hian hna tha tak tak, buttoning emaw ziak emaw ang chi harsatna tihna a ni.
• Carpal Tunnel Syndrome : A bik takin PHP-1 vei tan. Hei hi kutphah chhunga nerve pakhat a compress a, kut a ti na a, a na a ni.
• Spinal stenosis a awm thin
• Sleep apnea : A bik takin naupangte tan.

Doctor-te hian engtin nge PHP hi an hriat theih?

PHP i vei nia i rinhlelh chuan i doctor chuan taksa a enfiah hmasa ang . I chhungkaw chanchin pawh an zawt ang . Chumi hnuah chuan test dang eng emaw zat an ti leh thei a, an natna hmuhchhuah chu an finfiah thei bawk. Chung zingah chuan:

• Thisen test : Hormone level tehna, a bik takin calcium, phosphorus, leh PTH level te teh thin ang che.
• Zun test : Zun chhunga calcium leh phosphorus awm zat enfiah thin ang che.
• Genetic testing : `GNAS` gene a inthlak danglam leh awm loh enfiah thin.
• Electrocardiogram (EKG) : Lungphun a danglamna a awm leh awm loh a enfiah thin.
• Kut X-ray : Ruh tliak leh thil dang dang a awm leh awm loh enfiah thin ang che.
• CT Scan (CT - Computed Tomography scan) : Thluak ah danglamna a awm em tih en nan.

Heng test atanga information a hmuh atang hian doctor chuan PHP status dik takin a nemnghet thei a ni.

PHP hi engtin nge enkawl a nih?

Hetiang dinhmun hi damdawi a la awm lo . Mahse, lungngai suh. Enkawlna leh enkawl dan dik tak i neih chuan i natna lan chhuah dan i thunun thei a, nun pangngaiin i nung thei bawk.

Enkawlna tum ber chu i thisena calcium leh phosphorus level dik tak awm reng hi a ni . Heng level te hi vawn reng hian symptoms nasa takin a tihziaawm thei a ni. Hei hi dam chhung zawnga enkawlna a ni .

Enkawlna kawng hrang hrangte chu:

• Calcium leh vitamin D supplement : pill emaw liquid emaw angin.
• Calcitriol capsules : Hei hi taksaa calcium awm zat tipungtu damdawi a ni.
• Calcitriol injection hmanga tihdam theih a ni
• Growth hormone emaw thyroid hormone thlak danglamna damdawi : a tul chuan.
• Calcium tamna, phosphorus tlem eitur : Nutritionist-in a thurawn angin.

A pawimawh ber chu damdawi lam thurawn uluk taka zawm a, a hun taka test neih hi a ni.

Engtikah nge Doctor ka hmuh ang?

PHP i neih chuan i doctor pan fo a pawimawh a, i calcium leh phosphorus level enfiah a pawimawh . He regular monitoring hian engkim control theih turin a pui dawn a ni.

Thâwk harsa nghal, taksa ruh na tak, emaw, seizures ang chi natna khirh tak tak i neih chuan, damdawi in hnai ber emergency room-ah kal nghal emaw, 1990 call emaw rawh.

PHP dinhmun nen hian eng nge i beisei theih ang?

PHP i neih chuan i Primary Care Physician nen in thawk dun chhunzawm zel tur a ni . PHP hian taksa peng hrang hrang tam tak a nghawng theih avangin i natna lan chhuahna bikte enkawl turin specialist engemaw zat i pan a ngai mai thei. I medical team-ah hian:

• Endocrinologist : Hormone lama mithiam bik an ni.
• Orthopaedic surgeon : Ruh nena inzawm harsatna nei tan.
• Naupang enkawltu : Naupang a nih chuan.
• Neurologists : Nervous system nena inzawm harsatna nei tan.
• Taksa lam thiamte
• Occupational therapist te an ni
• Ei leh in lama mithiamte
• Ha enkawltu te
• Geneticist te chuan an ti a
• Pain management lama mithiamte an ni

I dam chhung zawng chu chutiang supplement chu i ei a ngai mai thei .

Natna chi leh nasat dan azirin hmasawnna leh rilru lama theihna a inang lo thei hle. Mahse , a tam zawkah chuan PHP vei te hian PHP nei lo te nen khaikhin chuan dam rei zawng an nei pangngai a ni . I doctor chuan i dinhmun a zirin i beisei tur a hrilh thei che a ni.

PHP hi thil awm lo tak a nih avangin nangmah ang bawka natna nei midang hmuh a harsa thei hle . A chang chuan mahni chauhna a awm thei bawk. Nangmah emaw i fa emaw hian PHP i vei tih hmuhchhuah a nih chuan, i doctor nen support group leh educational resources chungchang sawipui rawh . Chungte chuan i natna lan chhuah dan leh nunphung zawng zawng tihchangtlun dan tur kawng zawn nan a pui thei che a ni.

Take-Home Thuchah a ni

Okay, chuvangin kan sawi tawh pseudohypoparathyroidism (PHP) chungchanga hriat reng tur thenkhat han thlir ila.

• PHP hi genetic condition awm lo tak a ni a, taksain parathyroid hormone (PTH) a chhang tha lo.
• Hei hian thisen a calcium a tihhniam bakah phosphorus a tipung bawk.
• A chi hrang hrang a awm a, chungte chu : PHP-1, PHP-2, leh PHP-3 te an ni .Awle. PHP-1 hian ruh a tidanglam thei a, chu chu AHO an ti a ni.
• Symptom hrang hrang a awm thei a, chu chu taksa ruh hring, rilru hahna, seizures, ha lama harsatna, tawi te, leh hmai zungbun te hi a ni .
• A chhan ber chu `GNAS` gene a mutation vang a ni .
• Damdawi famkim awm lo mah se, dam chhung enkawlna (calcium, vitamin D, ei leh in bik) hmangin a natna lan chhuah dan chu a thunun theih a ni.
• Medical checkup neih fo leh specialist doctor-te puihna a pawimawh hle.
• Mi tam zawk chuan nun pangngai an hmang thei .
• Rilru chak taka awm reng tur chuan support group atanga tanpuina hi a pawimawh hle.

I theihnghilh suh, nangmah chauh i ni lo. Hei hi thil awm lo tak ni mahse, damdawi lam thurawn leh puihna dik tak nen chuan uluk taka enkawl theih a ni. Chakna i mamawh hunah doctor, chhungte leh thiante an awm reng tih hre reng ang che.

` Pseudohypoparathyroidism, PHP, parathyroid hormone, calcium, phosphorus, genetic natna, AHO