Damdawi Verzenio, hnute cancer a darh huna pek thin chungchang hi i zir dawn teh ang? (Hnute cancer natna hrik darh) .

Doctor-in hnute cancer chu taksa peng dangah a darh tawh, chu chu ‘metastatic’ a lo ni tawh tih a hrilh che chuan hlauhna leh lungkhamna nasa tak nei hi thil pangngai a ni. Amaherawhchu, tunlai damdawi lam thiamna a lo thang chho zel a, tunlai hian hetiang natna vei enkawlna tha tak tak a awm ta a ni. Chutiang damdawi pakhat, beiseina thlentu chu Verzenio a ni. Chuvangin vawiin hian he damdawi Verzenio an tih hi tawi te tein kan sawi dawn a, a hnathawh dan te, a hman lai hian eng thil nge fimkhur tur tih te hi han sawi ila.

Verzenio hian taksa chhungah engtin nge hna a thawh?

A awlsam zawngin, Verzenio hi damdawi chi khat, ``kinase inhibitors.`` tih hming pu damdawi a ni a, kan taksaah hian enzyme awm angin han ngaihtuah teh, chu chu ``messenger`` ang maia thawk, cell inkara thu leh hla phur chhuaktu a ni. Hengte hi ``kinases`` kan tihte hi an ni.`` Cancer cells hi heng special messengers atanga siam a ni a, chu chuan an inthen darh a, chak takin an lo thang lian a ni.

Verzenio hian hna a thawk a, `cyclin-dependent kinases 4 and 6 (CDK4 leh CDK6)` an tih messenger te hnathawh a block a, chungte chuan cancer cell te chu an thanlen theih nan signal an thawn thin a ni. A dik tak chuan, chu thuchahte chu zinkawng chanve velah a block vek a ni . Chutiang chuan CDK4 leh CDK6 enzyme te hnathawh an chawlhsan chuan cancer cell te hian inthen darh leh thanlenna tur signal an hloh ta a ni. Chuvang chuan cancer cell te thanna chu a titawp emaw a ti hniam emaw a ni . Hei hian tumor tihtlem nan a pui bawk.

Verzenio hi eng hnute cancer atan nge hman a nih?

He damdawi hi hnute cancer chi hrang hrang tan pek a ni lo. A bik takin:

• Hormone receptor (HR)-a positive leh...
• Mihring epidermal growth factor receptor 2 (HER2)-negative a ni

Hnute cancer chi khat, metastatic breast cancer an tih atan hman a ni. Cancer chu hnute pawn lam atanga taksa peng dang, thin, lung emaw ruh emaw-ah a darh tawh chuan pek a ni bawk.

A chang chuan he damdawi hi hormone enkawlna dang nen an pe dun thin. Mahse, cancer a darh tawh a, natna hian chemotherapy leh hormonal treatment pahnih a chhan loh chuan Verzenio chauh pek theih a ni . Hei hi i enkawltu doctor-in a rel vek a ni.

Verzenio hi engtin nge kan lak ang? Eng thil nge i hriat reng tur?

Verzenio hi pill a ni. I hman hunah heng thilte hi i fimkhur tur a ni.

• He pill hi ni khatah vawi hnih i ei a ngai a ni .
• Chaw ei hma emaw, ei zawhah emaw i ei thei a, mahse nitin hun inang deuhah ei tum ang che .
• Tablet chu a pumin ei tur a ni . Tihchhiat suh, tikehsawm suh, chew suh.
• Pill chhe tawh, chip tawh, chhe tawh reng reng ei suh .Chutih hunah chuan i doctor ko la, a chanchin chu hrilh rawh.
• Damdawi i ei hnua i luak chuan chu dose chu skip rawh. Pill extra ei loh tur a ni . Pill dang chu a hun ruatah ei rawh.

I doctor chuan i cancer control theih hma emaw, side effect na tak i neih hma emaw chuan he damdawi hi ei chhunzawm zel turin a fuih ang che. Side effect engemaw zat i neih chuan i doctor chuan i dose tihhniam a tum mai thei a, rei lo te chhung chu chawlhsan a, tihtawp vek a tum thei bawk.

Verzenio hi engtiang chiahin nge a thawh hlawk tak tak? (Clinical Trial Results atanga a lan dan)

He damdawi hi clinical trial hlawhtling tak tak engemawzat result atanga pawm a ni. Chutiang trial atanga result chu han thlir thuai ila.

Engtin nge doctor hian enkawlna kal zel dan a enfiah?

Damdawi i ei tan hnuah doctor chuan a enkawl reng ang che.

• Scans: Damdawi ei tan atanga kar 6 vel hnuah scan hi tih thin a ni a, cancer hian damdawi a chhan dan tur a enfiah thin.
• Thisen Test: Hei hi a pawimawh hle. I thisena cell level, thisen var, neutrophil, leh platelet te chu damdawi hian i taksa tan him takin hna a thawk em tih enfiah fo thin a ni.

Side effects a awm chuan engtin nge kan enkawl ang?

Cancer damdawi ei hian side effect a nei fo thin. A pawimawh ber chu i thil tih danglam emaw, i rilru hahna emaw i neih apiang, a tenau pawh ni se, i doctor hnenah hrilh hi a ni.

• Thisen test neih fo: Verzenio hian a chang chuan thisen var a tihhniam thei. Hei hi ``neutropenia'' an ti a, hei hian natna khirh tak tak a thlen thei a ni. Chuvang chuan i doctor-in a tih tur thisen test zawng zawng lak vek a pawimawh.
• Pum natna: Luak chhuak, luak chhuak, leh luak chhuak hi a tam hle. Chûngte chu ei tûr bland, thau tlem ei a, chaw lian ni lovin chaw tê ei hian a thunun theih a ni. Mahse, i riltam a nasat chuan doctor hnenah i hrilh nghal tur a ni . A tul angin thurawn a pe ang che.
• Side effects pawi tak dang: Thisen zam (ke-a hring emaw, hliam emaw) i lung a tichhe thei, khuh, thawk harsa, thawk harsa tih ang chi i neih chuan i doctor hnenah pawh i hriattir nghal tur a ni.

Thil danglam bik hriat tur a awm em?

Ni e, thil tlemte dang a awm.

• Grapefruit ei la, juice ei rawh: Grapefruit hian taksa a ti chhe thei lo Verzenio. Hei hian taksaa damdawi level chu a tul lovah a tisang thei a, side effect a tipung thei a ni.
• Damdawi thenkhat: He damdawi nen hian antifungal damdawi ketoconazole ang chi ei hian side effect hlauhawm tak a nei thei a ni. Chuvangin, i damdawi ei zawng zawng (vitamin leh supplement te pawh tel) i doctor hnenah hrilh rawh .
• Natna dang: 1.1.Hriselna lama harsatna dang, liver natna ang chi i neih chuan i Verzenio dose hi tihdanglam a ngai mai thei. I doctor nen i hriselna chanchin kimchang sawi rawh.