SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion), taksain tui tam lutuk leh chi tlem lutuk a vawn tlat thin

Nilengin tui in tam a pawimawh tih kan hre vek. Infiamna huna i thawmhnaw tam lutuk hian a chang chuan i taksain tui chauh ni lovin electrolyte a hloh tih i hre tawh mai thei. Mahse, tui tam lutuk hi harsatna lian tak a nih theih hun a awm tih i hria em? Dik tak chuan chutiang a nih chuan i taksaa electrolyte hlu tak tak i hloh thei a ni. Chu chu vawiina kan sawi tum dinhmun chu a ni a, chu chu SIADH an ti a ni.

A awlsam zawngin SIADH chu eng nge ni?

A hming sei tak SIADH hi ‘Syndrome of Inappropriate Antidiuretic Hormone Secretion’ tihna a ni. Okay, a hming hi a buaithlak deuhin a ri a ni lawm ni? Hei hi awlsam takin i hrethiam ang u. Kan taksa hian hormone bik antidiuretic hormone tih a nei a . Mizo tawngin hei hi Antidiuretic Hormone , a tawi zawngin (ADH) an ti a. He hormone hi kan thluak hypothalamus ah siam a ni a, pituitary gland atanga chhuak a ni. He ADH hormone hnathawh ber chu kan kal (kidney) te zirtirna a ni. Chu chu, "Okay, tunah chuan taksaah tui a awm tawh a, thenkhat chu zun angin i paih chhuak ang u" tih leh "Ni lo, taksaah tui a awm lo, taksa chhungah thenkhat chu dah belh leh ila" tihna a ni. He hormone hian kal (kidney) a thunun a ni. Kan taksaah hian "tui controller" ang mai a ni. Tunah chuan han ngaihtuah teh, eng emaw chhan vanga he ADH hormone hi a chhuah tam lutuk leh a dik lo a nih chuan eng nge thleng ang? Tichuan chu hormone chuan kal (kidney) chu "tui vawng reng la, tui vawng reng rawh" tiin a hrilh fo thin. Chumi rah chhuah chu kan taksa hian a tul lovah tui a vawng tan ta a ni. Kan taksaah tui a pung khawm chuan kan thisen chu a dilute zual sauh sauh a. A bik takin kan nerve leh muscle hnathawhna atana pawimawh tak sodium concentration chu hlauhawm takin a tlahniam a. Sodium hi kan taksaa electrolyte awm ber pakhat a ni. Damdawi lamah chuan he thisena sodium tlakchhamna hi hyponatremia an ti a. SIADH-a symptom hmuh tam tak hi he sodium level hniam vang a ni.

SIADH awm chhante chu engte nge ni?

Chutiang chuan ADH hormone hi a tul lo taka a pun chhan pakhat a awm lo va, mahse chhan engemaw zatin a nghawng thei a ni. A chang chuan hei hi natna dang side effect angin a thleng thei bawk. A chhan berte chu eng nge ni tih i lo en ang u.

Hetiang dinhmun hi eng symptoms nge ni thei ang?

SIADH hi a chhan ber chu tui tlakchhamna a punna leh thisenah sodium a tlahniam vang a ni a, a lan chhuah dan tam tak chu hei nen hian a inzawm tlat a ni. Heng symptoms te hi a lang nghal lo mai thei a, mahse zawi zawiin a lo awm thei.

• Nausea leh luak chhuak
• Chak lo anga inhria , chau
• Lu na
• Muscle na leh cramps, sa chi hrang hrang a rawn inher chhuak ang maia hriat
• Restlessness, thinrimna rang
• Hriatrengna hloh leh ngaihtuahna seng harsa (Confusion) .
• Balance hloh leh kal harsa

A pawimawh ber chu heng symptoms te hi SIADH tan bik a ni lo. Heng symptoms te hi natna dang tam takah hmuh theih a ni. Chuvangin heng symptoms te hi i neih chuan doctor pan a, engmah ngaihtuah lovin thurawn lak a pawimawh hle.

Engtin nge doctor hian hei hi a hriat chian?

Doctor i pan chuan i natna lan chhuah dan te, i damdawi ei tur te, i chhungte zingah hian heng natna hi an nei tawh em tih te a zawt hmasa ang. SIADH nemnghet tur chuan thisen leh zun test vawi tam tak i tih a ngai ang .

• Thisen test: Hengte hian thisen a sodium leh potassium awm zat a enfiah thin. Tin, thisen osmolality an teh bawk a, chu chu thisena thil hmin (dissolved substances) awm zat a ni. SIADH -ah chuan thisen a dilution vangin he value hi a tlahniam thin.
• Urine test: Zun chhunga sodium awm zat leh zun osmolality te enfiah thin a ni. SIADH-ah chuan taksain tui a vawn tlat avangin zun chhuak chu a concentrate hle. Chuvangin zun osmolality chu nasa takin a pung a ni.

Heng test result atang hian doctor chuan hei hi SIADH a nih leh nih loh a hre thei ang.

SIADH enkawl dan tur chu engte nge ni?

Enkawlna chu thil engemaw zatah a innghat a ni. I doctor chuan i kum, i hriselna, i SIADH awm chhan leh i natna lan chhuah dan nasat dan te a ngaihtuah ang. 1. Fluid restriction: Mi tam zawk tana enkawlna hmasa ber leh pawimawh ber chu nitin tui i in zat tihtlem hi a ni. Hei hian i taksain tui a vawn tam loh nan a pui ang. Fluids hian tui chauh a kawk lo va; i in apiang, tea, coffee, thei tui, leh soup ang chi te pawh an tel a ni. I doctor chuan nitin engzat nge i in theih tih a hrilh ang che. 2. IV saline: I natna lan chhuah dan a nasat a, chu chu i sodium level a hniam hle tihna a nih chuan damdawi inah dah a ngai mai thei a, IV saline pek i ngai mai thei. Hei hi zawi zawiin leh uluk taka i sodium level a lo awm leh theih nan tih a ni. 3. A chhan bulpui enkawl dan: I SIADH thlentu chu thluaka tumor a nih chuan operation hmanga lakchhuah a ngai mai thei. A chhan chu lung infection a nih chuan antibiotics pek tur a ni. Chumi awmzia chu a chhan enkawl a nih hunah SIADH pawhin a mah chauhin a rel dawn tihna a ni. 4. Damdawi: Mi thenkhat tan, a bik takin an natna a la awm reng (Chronic SIADH) chuan ADH hormone hnathawh tikhawlo thei damdawi emaw, taksaa tui awm zat control tu damdawi emaw pek theih a ni.

Prognosis chu eng nge ni?

A tam zawkah chuan SIADH awm chhan bulpui ber chu enkawl theih a nih chuan a natna hi a dam vek thei a ni. Amaherawhchu, hetah hian thil hlauhawm pahnih kan ngaihven a ngai a ni.

• Sodium level tlahniam nghal, rang taka: Chutiang a nih chuan thluak cell-ah tui a lut thei a, cerebral edema a thlen thei a ni. Hei hi thil hlauhawm tak leh nunna atana hlauhawm tak a ni.
• Sodium level hniam tak tak, rang taka pung: Enkawl laiin sodium level hi rang tak leh rang taka tihsan a nih chuan natna khirh tak dang ‘Osmotic Demyelination Syndrome’ tih a thlen thei a, chu chuan thluaka nerve cells a tichhe thei a ni.

Hei vang hian sodium level hniam enkawlna hi doctor enkawlna hnuaiah damdawi inah tih a ngai a ni .

SIADH i vei nia i rinhlelh chuan a tha ber chu a rang thei ang bera Doctor pan hi a ni. I natna hriatchhuah leh enkawl i nih thuai poh leh harsatna lian tham i pumpelh theihna a sang zawk.

Take-Home Thuchah a ni

• SIADH hi taksain hormone ADH a siam chhuah tam lutuk avangin a tul lova tui a vawm a, thisenah sodium (salt) level a tlahniam a ni.
• Natna lan chhuah dan, luak chhuak, lu na, leh rilru buai te a awm thei. Hengte hi natna dang chhinchhiahna a nih avangin damdawi lam thurawn lak a pawimawh hle.
• Hetiang dinhmun hi thisen leh zun test hmangin dik takin a hriat theih a ni.
• Enkawlnaah hian tui tihtlem, saline pek, leh SIADH awm chhan bulpui enkawlna te a tel.
• Sodium level tlahniam nghal te, enkawl laia sodium level sang nghal te hi a hlauhawm hle. Chuvangin damdawi lam enkawlna hnuaia inenkawlna lak a pawimawh hle.

SIADH, Syndrome of Inappropriate Antidiuretic Hormone Secretion, Antidiuretic Hormone, Sodium tlakchhamna, Hyponatremia, Hormone lama harsatna, Kal, Electrolyte inthlauhna