He aha ēnei prostaglandin? He aha te hiranga o ēnei ki ō tātou tinana?

I tēnei rā ka kōrero tātou mō tētahi matū iti e hangaia ana i roto i tō tātou tinana, ā, he tino rerekē tana mahi. Ko te ingoa o tēnei ko ngā prostaglandin . Kāore pea koe i rongo i tēnei ingoa i mua. Engari, e mōhio ana koe ki te nui o te pānga o ēnei mea iti ki te hauora o tō tātou tinana me ngā tukanga o ia rā! Nō reira, i tēnei rā ka kōrero tātou mō ēnei prostaglandin i roto i tētahi huarahi māmā, ngāwari hoki ki te mārama.

He aha tonu ngā prostaglandin?

He whakarāpopototanga noa iho, ko ngā prostaglandin he rōpū lipid e hangaia ana i roto i ō tātou tinana ina he kino te kiko, ina he mate rānei, ā, he rite tonu tā rātou mahi ki ngā homoni. He maha ngā momo rerekē o ēnei, ā, ka āwhina i te whakahaere i ngā tukanga nui o roto i ō tātou tinana.

Whakaarohia rātou he karere iti i roto i ō tātou tinana. Ina he raruraru kei tētahi wāhi, ka hangaia ēnei karere ki reira tonu, ka tuku tohu ki ētahi atu pūtau kia mahi i tā rātou e tika ana.

Ko te homoni kotahi anō tēnei?

Tērā pea kei te whakaaro koe, "Nō reira, he momo homoni tēnei?" Inaa, ko ngā prostaglandin he momo ngako he rite ki ngā homoni. Ko ngā ngako he waikawa ngako, he mea hanga mai rānei i ō rātou pūtake. Ka hangaia ēnei prostaglandin e ō tātou tinana mai i te waikawa ngako e kiia nei ko te waikawa arachidonic.

Ka kiia ēnei he homoni nā te mea ka whakarite i ngā mahi maha i roto i te tinana, ka tohutohu hoki i te tinana ki te mea hei mahi me te wā tika hei mahi.

Engari, he rerekē ēnei i ngā homoni tūturu. Me pēhea koe e mōhio ai? Kāore ngā prostaglandin e mahi pērā i ngā homoni e hangaia ana e ngā repe i roto i tō tātou pūnaha endocrine ka tukuna ki roto i te toto. Engari, ka hangaia ēnei e ō tātou kiko i te wāhi o te kino, o te mate rānei, te wāhi e puta ai te mahi. Koinei te mea e motuhake ai rātou.

He aha te painga o ngā prostaglandin ki ō tātou tinana?

Ina hoki, he maha ngā momo prostaglandin, ā, he rerekē anō hoki ngā kaiwhakawhiwhi e aro atu ana ki a rātou. Ko te tikanga ka kitea ō rātou pānga i roto i te nuinga o ngā wāhanga o tō tātou tinana. Ko te pānga o te prostaglandin e whakawhirinaki ana ki ētahi āhuatanga:

• Te okana, te kiko rānei e hono ana ki a ia.
• Te kaiwhakawhiwhi e herea ana e ia.
• He tukanga, he āhuatanga rānei e puta ana i roto i te tinana.

Kia tirohia ētahi o ngā mahi matua a ēnei prostaglandin:

• Ka āwhina i te tīmatanga o te hanganga toto totoka i te wāhi o te whara, ka taea rānei e ia te aukati.
• Ka whānui haere ngā oko toto (vasodilation) ka whaiti rānei (vasoconstriction), ka pā tēnei ki te rere o te toto .
• Ka āwhina i te tukanga whakaora .
• te mumura (Koinei te take e pupuhi ai, e whero ai hoki ina pāngia koe e te patunga .
• He āwhina ki te tīmata i te whānautanga i te wā e hapū ana (whakaoho whānau) .
• I te wā o te paheketanga, ka whakawhāiti te kōpū, ā, ka āwhina i te whakaheke i te arai kōpū (endometrium).
• E pā ana ki te whakaputa uri .
• Ka pā te kirika .
• Te whakahaere i tō mamae .
• Ka āwhina ki te whakaiti i te pēhanga i roto i te kanohi.
• Ka whakaiti i te tukunga waikawa o te puku.
• Ka whakakorikori, ka whakangā rānei ngā uaua maeneene o tō tātou ara kai.
• Ka whakahaere i te mahi a ētahi atu homoni.

Ko te mea nui ko te poto rawa o te haurua-ora o ngā prostaglandin. Arā, he poto noa iho te wā e mahi ai rātou. Nō reira, ka pā noa iho ki ngā pūtau e tata ana. Ka taea te hanga e ngā momo kiko o roto i tō tātou tinana.

Me tango he tauira mai i te oranga o ia rā?

Whakaarohia kua motu tō maihao. Ahakoa he patunga iti noa iho, he nui te mahi ka taea. Anei te āwhina a ngā prostaglandin:

1. Ka mutu te toto: Tuatahi, ka tukuna ngā prostaglandin mai i ngā kiko o te motu. Ka kī atu ēnei ki ngā pereti toto i roto i te toto kia "huihui wawe, kia kati te patunga, kia mutu te toto." Kātahi ka puta he toto totoka ki reira.

2. Whakahaere i ngā oko toto: Muri iho, ka puta mai tētahi atu momo prostaglandin mai i ngā kiko i te wāhi i whara ai, ā, ka paku whakawhāiti ngā oko toto. Ka kiia tēnei ko te vasoconstriction . Mā tēnei ka nui ake te whakaiti i te toto.

3. Mumura (pupuhi): Kātahi ka tukuna ngā prostaglandin, ka puta ai te mumura. Ka puta te wai mai i ngā oko toto ki roto i ngā kiko, ka pupuhi te patunga, ka whero, ka wera hoki. Kaua e manukanuka, he pai tēnei pupuhi. Nā te mea ka ārai i ngā mea pēnei i ngā iroriki kua uru pea ki te patunga kei haere ki ētahi atu wāhanga o te tinana. He mahi anō tā ēnei prostaglandin mumura. Arā, ka kawea mai e rātou ngā pūtau toto mā e kiia nei ko ngā phagocytes ki te patunga. Ko ēnei pūtau ngā mea e 'kai' ana i ngā iroriki me ngā pūtau mate, ā, e horoi ana i te patunga.

4. Ka tangohia te toto totoka ina ora: Hei whakamutunga, ina ora katoa te patunga, ka hoki mai ngā prostaglandin ka whakarewa i te toto totoka ka tangohia. Nā te mea kāore e hiahiatia kia noho tonu ki reira.

Kua kite koe i te nui o te mahi a ngā prostaglandin ahakoa i runga i tētahi patunga iti?

Nā, he pai, he kino rānei ngā prostaglandin?

He pātai tino nui tēnei. I raro i ngā āhuatanga noa, ka whakamahia ngā prostaglandinHe mea nui, he mea ā-taiao mō ō tātou tinana. He mahi nui tā rātou ki te whakahaere i ngā tukanga ā-tinana pēnei i te mamae me te mumura. Ko te tukanga mumura noa he huarahi e whakamahia ana e ō tātou tinana hei tiaki i a rātou anō mai i ngā kino atu.

Heoi, i ētahi wā ka piki haere te nui o ngā prostaglandin i roto i te tinana, kāore e hiahiatia. Koinei te wā ka tīmata ai ngā raruraru. Ina tupu tēnā, ka puta te mumura tonu me te mamae e kore e taea te whakamanawanui. I roto i ēnei āhuatanga, ka taea e te nui rawa o ngā prostaglandin te arahi ki ngā mate mau tonu me ngā tohu mamae.

Hei tauira, ahakoa he mea nui ngā prostaglandin mō te paheketanga, ki te nui rawa te pikinga, ka puta pea te toto mamae me te toto nui o te paheketanga (menorrhagia) .

Te mahi a ngā prostaglandin i te wā e hapu ana

I te wā e hapu ana, e whānau ana hoki, ka whakaputahia e ngā pūtau i roto i te kōpū ngā prostaglandin. Ka āwhina ēnei ki te whakawhānui i te cervix me te whakawhāiti i te kōpū. Ka āwhina ēnei whakawhāiti i te pēpi ki raro i te awa whānau.

Waihoki, ka whakamahia e ngā tākuta ētahi prostaglandins waihanga hei whakaoho i te whānautanga mēnā ka tūtohu rātou kia tīmata te whānau i mua i te tīmatanga maori.

Me pēhea te whakamahi i ngā prostaglandin i roto i te rongoā?

He maha ngā momo prostaglandin hangai e whakamahia ana e ngā tākuta hei rongoā i ngā momo āhuatanga me ngā āhuatanga. Me titiro tātou ki ētahi tauira.

• Travoprost: Whakamahia hei rongoā mō te karuāra me te toto toto tiketike.
• Dinoprostone: Ka āwhina ki te whakawhānui i te kaki o te kōpū i roto i ngā whaea e tata ana ki te mutunga o tā rātou hapūtanga me te tīmata i te whānautanga.
• Alprostadil: Nō roto tēnei i tētahi akomanga rongoā e kiia nei ko ngā vasodilator. Ka whakanui ake i te rere o te toto. Ka āwhina i te rongoā i ētahi mate ngakau i roto i ngā pēpi (hei tauira, te mate ngakau cyanotic) me te ngoikore o te ure (ED) i roto i ngā tāne.
• Misoprostol: I ētahi wā, ka hoatu tēnei rongoā mā te pūhā hei aukati i te toto nui i muri i te whānautanga (te toto i muri i te whānautanga).
• Iloprost: Hei rongoā mō te toto toto tiketike me te mate e kiia nei ko te mate CREST.

Nā te nui rawa o te prostaglandin ka pā mai te mamae me te mumura koretake, ka whakamahia hoki e ngā tākuta ngā rongoā hei whakaiti i ngā pānga o ngā prostaglandin, hei aukati rānei i a rātou. Ko ngā rongoā e whakamahia whānuitia ana hei aukati i ngā prostaglandin ko:Ngā Rongoā Ārai-mumura Kore-steroidal (NSAID). E mōhiotia whānuitia ana ēnei he rongoā whakamamae mamae. Ko ētahi tauira ko te aspirin (hei tauira, Excedrin®), ibuprofen (hei tauira, Advil®, Motrin®), me te naproxen sodium (hei tauira, Aleve®).

He aha ngā raruraru ka puta mai i ngā prostaglandin?

I ētahi wā ka nui rawa ngā prostaglandin e hangaia ana e ō tātou tinana, kāore rānei i te nui. Ka arahi pea tēnei ki ētahi raruraru hauora me ngā tohu.

Ngā prostaglandin nui rawa

Ki te piki haere te nui o ngā prostaglandin i roto i te tinana, kāore e tika ana, ka puta he mumura koretake, kāore hoki e whai hua i roto i te tinana. Anei ētahi o ngā mate hauora ka puta:

• Mamae mau tonu.
• Te whakanui ake i te aro ki te mamae.
• Te mamae o te paheketanga, te mamae rānei o te paheketanga (dysmenorrhea).
• Te toto nui o te paheketanga.
• Ētahi momo mate pukupuku.

Te kore o ngā prostaglandin

I ētahi wā, kāore pea te tinana e whakaputa i te nui o ngā prostaglandin hei whakaora i te patunga, hei tīmata rānei i te whānautanga i muri i te haputanga katoa. Ahakoa kāore ēnei āhuatanga e pā ana ki ngā āhuatanga mau tonu, ka taea e ngā prostaglandin hangai te āwhina. Ka whakamahia e ngā tākuta ngā prostaglandin hangai hei rongoā i ngā mate puku me te glaucoma. Ka taea hoki e rātou te āwhina i te tīmatanga o te whānautanga.

Āhea koe me toro atu ki te tākuta mō ngā raruraru e pā ana ki ngā prostaglandin?

Mena kei te pāngia koe e te mamae tonu, me te mumura mau tonu rānei , me toro atu ki te tākuta. Ahakoa he maha ngā take mō ēnei āhuatanga, ko tētahi pea take ko te mahi a ngā prostaglandin i roto i tō tinana.

He mate noa te dysmenorrhea e pā ana ki ngā prostaglandins, ā, he mate hauora e hiahia ana kia arohia e te rata. Mena he mamae tō paheketanga, kāore e taea te whakaora mā te tango i ngā rongoā whakamamae mamae (NSAID), kōrero ki tō tākuta. I ētahi wā, ka puta te mamae o te paheketanga i tētahi mate hauora, pērā i te endometriosis, i te uterine fibroids rānei .

He matū tūturu ngā prostaglandin, he matū kaha e pā ana ki ngā āhuatanga maha o ō tātou tinana. Ahakoa he mea nui mō ngā tukanga tinana pēnei i te whakaora, ka taea e te nui rawa o te prostaglandin te whakararu i te mamae mau tonu, te mumura, me te whakaheke i te kounga o te oranga. Mena kei te pāngia koe e te mamae, te mumura rānei, tirohia he tākuta kia kitea ai te take me te tiki i tētahi mahere maimoatanga tika.

Karere Tangohia ki te Kāinga

Āe, kua maha ngā kōrero mō ngā prostaglandin i tēnei rā, kāore? Ko te mea nui kia maumahara ko ēnei he rite ki ngā karere matū iti e hangaia ana i roto i ō tātou tinana, ā, he tino nui te mahi a ēnei.

• He maha ngā āwhina a ēnei, pērā i te whakaora i ngā patunga, te aukati i te toto, te whakahaere i te mumura, te āwhina i te whānautanga, me te whakahaere i te paheketanga.
• Waihoki, ki te nui rawa te pikinga o ēnei, ka puta pea ngā raruraru pēnei i te mamae me te pupuhi tonu.
• Mena kei te pāngia koe e te mamae tonu, te pupuhi, te mamae nui rānei o te paheketanga, he mea nui kia rapu tohutohu hauora me te kore e warewarehia, nā te mea pea ka puta mai i te kore taurite o ēnei prostaglandin.

Nō reira, mā te mōhio ki ēnei mea whakamiharo e tupu ana i roto i ō tātou tinana ka nui te āwhina ki te pupuri i tō tātou hauora.

Ngā prostaglandin, ngā homoni, te mamae, te pupuhi, te mumura, te paheketanga, te haputanga