He aha te DHT? He aha ngā pānga ki tō tinana? (Dihydrotestosterone)

Kua rongo koe i te DHT, i te Dihydrotestosterone rānei? Āe pea, kāore pea. Engari he mea tino nui tēnei mō tō tātou tinana, inā koa mō te hauora o ngā tāne. Nō reira, i tēnei rā ka kōrero tātou mō tēnei DHT i roto i tētahi huarahi māmā e mārama ai koe.

He aha te DHT (dihydrotestosterone)? He māmā noa iho...

He whakarāpopototanga noa iho, he homoni motuhake te DHT e āwhina ana ki te whakawhanake i ngā āhuatanga tāne . Kei te mōhio koe, he rite ngā homoni ki ngā karere iti e whakahaere ana i ngā mahi katoa o roto i tō tātou tinana. Nō roto hoki te DHT i tētahi rōpū homoni e kiia nei ko te Androgen. Ko te Androgen te ingoa i hoatu ki ngā homoni e puta ai ngā āhuatanga tāne.

Whakaarohia, ka tīmata te mahi a te DHT i roto i te tinana o te tāne mai i te wā i roto ia i te kōpū. Kātahi ka rerekē te mahi a te DHT i ngā wā rerekē o tōna oranga. Ahakoa kāore i te tino mārama ngā kaipūtaiao ki te pānga o te DHT ki ngā wāhine, e whakaaro ana rātou ka pā pea ki te tipu o ngā makawe i te tinana me ngā wāhi tūmataiti.

Ko te androgen matua i roto i te tāne pakeke ko te testosterone . Tata ki te 10% o tēnei testosterone ka hurihia hei DHT i ia rā . Ka puta tēnei tukanga i roto i te kiri huri noa i ngā ira tangata me te repe prostate i roto i ngā tāne. I roto i ngā wāhine, ka puta tēnei i roto i te kiri. Ka puta anō hoki i ngā wāhi pēnei i tō tātou ate. Nā te mea he nui ake te testosterone i roto i ngā tinana o ngā tāne, he nui ake hoki ō rātou taumata DHT.

He aha te pānga o te DHT ki ō tātou tinana?

He rerekē ngā mahi a te DHT i ngā wāhanga rerekē o te oranga o te tāne. He mea nui rawa atu i te wā o te whanaketanga o te kukune me te pakeketanga .

Heoi, kāore i rite ki te testosterone, kāore te DHT e whai wāhi nui ki te pupuri i ngā mahi a te tinana i roto i te tāne pakeke. I te pakeketanga, ka kitea te DHT i roto i ngā āhuatanga pēnei i te whakanui o te repeure me te ngaro o te makawe o te tāne.

Te tūranga o te DHT i te wā o te kukunetanga

I roto i te kōpū, ka whanake ngā whekau ira tangata o te pēpi hei tāne, hei wahine rānei, i runga i tētahi taiao homoni motuhake. Mō te tama, ka mahi tahi te DHT me ētahi atu homoni (tae atu ki te testosterone ) hei pehi i te whanaketanga o ngā āhuatanga ira tangata wahine, hei whakatairanga hoki i te whanaketanga o ngā āhuatanga ira tangata tāne .

He mea nui te DHT mō te whanaketanga o ngā ira tāne o waho, arā, te ure me ngā rauropi, i roto i te tamaiti. Ka āwhina anō hoki te DHT i te whanaketanga o te repe prostate.

DHT i te wā o te pakeketanga

I te pakeketanga o te tamaiti, ka āwhina te DHT i te ure me ngā porotiti kia tipu ake. Ehara i te mea koinā anake, engari ko te DHT anō hoki te kawenga matua mō:

• I te mataTe whakatipu pahau.
• Te tipu haere o ngā huruhuru o te tinana.
• Te tupu o te makawe i ngā wāhi tūmataiti.
• Te tipu o te repeure .

Ka aha mēnā ka piki ake ngā taumata DHT?

Ko ētahi āhuatanga hauora e pā ana ki te taumata DHT teitei. Me titiro tātou ki ēnei āhuatanga:

• Te Hyperplasia Prostatic Pai (BPH)
• Matepukupuku prostate
• Te ngaronga o te makawe o ngā tāne (te mate makawe o ngā tāne )
• Te Mate Pūkahukahu Polycystic (PCOS) (i roto i ngā wāhine)

Te Hyperplasia Prostatic Pai (BPH) me te DHT

Ko te Benign Prostatic Hyperplasia (BPH) he whakanui i te repe prostate. He mate tino noa tēnei i roto i ngā tāne neke atu i te 50 tau te pakeke .

Ka taea e tō repe prostate te whakaputa i te nui o te DHT. Ka whakaoho tēnei DHT i te mahi noa o te repe prostate, ā, he maha ngā wā ka whakanuia te repe prostate. Ka taea e tēnei BPH te whakararu i ngā raruraru pēnei i te uaua ki te mimi me te koretake o te moepuku .

Te mate pukupuku prostate me te DHT

Ko te hunga e pangia ana e te matepukupuku repeure he nui te taumata o te DHT. Ka puta te matepukupuku repeure i te pikinga ake o te mahi DHT i roto i tō repeure, me ētahi whakarerekētanga ira e meinga ai ngā pūtau repeure kia tipu korekore noa iho.

Te ngaronga o te makawe (androgenetic alopecia) me te DHT

Ko te androgenic alopecia te mea e kiia nei e tātou ko te pakira tauira tāne . I roto i tēnei āhuatanga, ka taka te makawe mai i te tihi me te mua o te mahunga. I roto i te wā, ka hoki whakamuri te raina makawe.

Ko tētahi o ngā take o tēnei ngaronga makawe ko te pikinga ake o te mahi DHT i roto i ō pūkahukahu. Tērā atu anō ngā take, pērā i ngā awe ira. Ina piki ake ngā taumata DHT, ka mimiti ngā pūkahukahu, ka poto te huringa tupu o te makawe, ā, i te mutunga ka hinga te makawe.

PCOS me te DHT

Ko te Polycystic Ovarian Syndrome (PCOS) he kore taurite o ngā homoni e pā ana ki ngā wāhine. Ka puta tēnei ina nui rawa ngā homoni androgen e whakaputaina ana e ā rātou ovaries, tae atu ki te testosterone. Ka hua ake tēnei i te nui o te DHT. Ka puta pea i tēnei he maha ngā tohu, tae atu ki te koretake o te paheketanga, te tipu nui o te huruhuru o te tinana (hirsutism), me te hakihaki .

Ka aha mēnā ka heke ngā taumata o te DHT?

Ko ētahi āhuatanga e pā ana ki te iti o te taumata DHT. Me titiro tātou ki ēnei āhuatanga:

• Te ngoikore o te 5-alpha reductase `(te ngoikore o te 5-alpha reductase)`
• Te iti o te testosterone / te hypogonadism o te tāne

Ko ngā taumata DHT iti iho i te tikanga e pāngia ana e ngā tāne. E whakapono ana ētahi kaipūtaiao ko ngā taumata DHT iti iho i roto i ngā kōtiro ka whakaroa i te pakeketanga.

Te ngoikore o te 5-alpha reductase me te DHT

Ko te 5-alpha reductase he whākōkī e āwhina ana ki te huri i te testosterone ki te DHT. Mā te whakarerekētanga ira e pā ana ki te hanga o tēnei whākōkī ka iti, ka ngaro rānei ngā taumata DHT. Ka kiia tēnei ko te 5-alpha reductase deficiency. He āhuatanga tēnei e tukuna iho ana mai i ngā mātua ki ngā tamariki (he tauira autosomal recessive) .

Ka pāngia te whanaketanga ā-ira o ngā kukune tāne ira (ngā mea he XY chromosomes) e te ngoikore o te 5-alpha reductase. Ko ngā pēpi tāne i whānau mai me tēnei ngoikoretanga ka whakaatu i ēnei āhuatanga:

• Kāore anō kia tino whanakehia ngā ira tangata o waho.
• Te kitea o ngā rauropi e mahi ana i roto i te tinana (kāore anō kia puta mai).
• He iti, he ngaro rānei te repe prostate.

He mea nui: I roto i ngā take kino o te ngoikore o te 5-alpha reductase, tera pea he ira wahine o waho o ngā pēpi tāne he ira XY ō rātou. Heoi, kāore te whakahekenga o te DHT e pā ki te whanaketanga o ngā testicles (ka taea tonu e rātou te whakaputa parāoa) me ngā ira o roto. He rerekē tēnei i te āhuatanga e kiia nei ko te Androgen Insensitivity Syndrome. He pai ngā testicles o te hunga whai i tēnei āhuatanga, ā, he pai, he teitei rānei ngā taumata testosterone, engari kāore i a rātou ngā kaiwhakawhiwhi androgen, nō reira kāore rātou e whakawhanake i ngā āhuatanga ira tuarua, ā, he iti ake hoki te momona o te ira.

Kāore ngā tama tāne e pāngia ana e te mate ira 5-alpha reductase deficiency e puta ai ngā huruhuru kanohi ina tae ki te pakeketanga. Heoi, kei te whakaputa tonu ō rātou tinana i te testosterone, e hua ake ai ngā mea pēnei i te reo hōhonu, te tipu uaua, me te whakanui ure.

Ngā taumata testosterone iti me te DHT

Ko te testosterone i roto i tō tinana ka huri hei DHT. Nō reira, ki te iti ō taumata testosterone, ka iti iho hoki ō taumata DHT i te mea noa. Ko tētahi atu ingoa mō ngā taumata testosterone iti ko te hypogonadism tāne.

E rua ngā momo matua o te hypogonadism tāne: ko te classical (ka puta mai i te whānautanga, i muri mai rānei i te pakeketanga) me te long-start starting. I runga i tō tau, ka pā mai ngā momo raruraru ki te hypogonadism tāne.

Me toro atu ahau ki te tākuta mō aku taumata DHT?

Ki te whakaaro koe kei a koe, kei tāu tamaiti rānei tētahi mate i puta mai i te iti, i te teitei rānei o te DHT, me kōrero koe ki tētahi tākuta.Kātahi ka taea e ia te mahi i ngā whakamātautau e tika ana, te tuku rānei i a koe ki tētahi tohunga ki te pūnaha endocrine, pērā i te endocrinologist.

He mea nui te dihydrotestosterone, arā, te DHT, mō te whanaketanga ā-ira tāne. Engari, ki te nui rawa, ki te iti rawa rānei ōna taumata, ka pā mai he raruraru pēnei i te kore whanaketanga o te ira tangata o waho, te nui haere o te repeure, me te ngaro o te makawe. Mēnā he āwangawanga āu mō ō taumata DHT, kaua e mangere ki te kōrero ki tō tākuta. Ka taea e rātou te whakahaere whakamātautau me te taunaki i ngā maimoatanga hei āwhina i a koe.

Ngā mea tino nui hei maumahara mai i tēnei tuhinga (Karere hei tango ki te kāinga)

• Ko te DHT he homoni androgen e āwhina nui ana ki te whakawhanake i ngā āhuatanga tāne .
• He mea nui te DHT mō te whanaketanga o ngā ira tāne o waho i te wā e whānau ana te tamaiti, me te tipu o ngā huruhuru kanohi me ngā huruhuru tinana i te wā e pakeke haere ana.
• Ka taea e ngā taumata DHT teitei te arahi ki ngā āhuatanga pēnei i te benign prostatic hyperplasia (BPH), te mate pukupuku prostate, te ngaronga o te makawe i roto i ngā tāne, me te PCOS i roto i ngā wāhine.
• Mena he iti ngā taumata DHT, ka pāngia te whanaketanga ā-ira tāne e ngā āhuatanga pēnei i te ngoikore o te 5-alpha reductase.
• Mena he ruarua, he āwangawanga rānei āu mō ō taumata DHT, he pai ake te rapu tohutohu hauora .

Ko tāku tumanako kua mārama ake koe ki te DHT. He mea nui te mōhio ki ēnei mea mō tō hauora!

` DHT, dihydrotestosterone, homoni, hauora o ngā tāne, testosterone, prostate, ngaronga makawe, PCOS