Kei te nui haere tō tinana, ā, kei te porotaka tō mata, pērā i te marama katoa? Me kōrero tātou mō te 'Cushing's Syndrome'!

Kua kite koe i ēnei wā tata nei kua paku rerekē te āhua o tō tinana, inā koa te taha o runga o tō tinana me tō puku, ā, kua porotaka haere tō mata, pērā i te marama katoa? Tērā pea he puranga ngako iti kei muri o tō kaki. Ehara ēnei i te mea noa iho. Kei muri i ēnei tohumate, tera pea he mate homoni e kiia nei ko te Cushing's Syndrome . Kaua e manukanuka, he mate tēnei ka taea te whakaora. Me kōrero noa tātou mō tēnei, i roto i te huarahi e mārama ai te katoa.

He aha te mate Cushing?

Ko te Cushing's Syndrome, te hypercortisolism rānei, he āhuatanga e puta ana ina nui rawa te homoni cortisol e whakaputaina ana e te tinana. Tērā pea kei te whakaaro koe he aha te cortisol. He homoni tino nui te Cortisol e whakaputaina ana e ngā repe iti e rua kei runga ake i ō tātou whatukuhu, arā, ngā repe adrenal. He nui te mahi a tēnei i roto i tō tātou tinana.

• Whakahaere i te toto toto .
• Ka whakahaere i ngā taumata huka toto.
• Ka whakaiti i te mumura i roto i te tinana.
• Ka āwhina i te huri i te kai e kainga ana e tātou hei pūngao.

Whakaarohia, ka puta katoa tēnei ina he tika te nui o te cortisol. Engari ina nui rawa tēnei homoni, ka tīmata te mahi a ētahi atu pūnaha o te tinana ki te hē. Koinei te mea e kiia nei e mātou ko te Cushing's Syndrome. He nui ake te kitea o tēnei mate i roto i ngā wāhine i ngā tāne. He tino kitea i roto i ngā tāngata i waenga i te 25 me te 40 tau te pakeke.

He aha ngā tino take o te mate Cushing?

He maha ngā take mō tēnei. Me titiro tātou ki ngā mea matua.

1. Te whakamahinga o ngā rongoā (te tino take)

Ko te tino take o tēnei mate ko te whakamahinga roa o ngā horopeta nui o ngā rongoā e kiia nei ko ngā glucocorticoids . E kiia ana ēnei he corticosteroids , he steroids rānei. Hei tauira, ko te prednisone.Ka taea e koe te tango i te rongoā e kiia nei. E taunaki ana ngā tākuta i ēnei rongoā mō ngā āhuatanga pēnei i te mate huango, te mate rumatiki, te lupus, i muri rānei i te whakawhitinga okana. He tino kaha ēnei rongoā hei whakahaere i te mumura. Heoi, ki te whakamahia ēnei mō te wā roa, ka puta te Mate Cushing hei pānga taha. Waihoki, ka puta tēnei āhuatanga nā te werohanga steroid tonu mō ngā mea pēnei i te mamae o ngā hononga me te mamae o te tuara. He tino onge tēnei āhuatanga nā ngā kirīmi steroid e whakamahia ana mō ngā mate kiri, engari ka taea te tupu.

2. Ngā pukupuku e puta ana i roto i te tinana

Ka taea hoki te piki ake o ngā taumata cortisol i roto i ō tātou tinana. Ko te take o tēnei he momo pukupuku e whanake ana i roto i te tinana.

• Ngā Pūkahukahu Pituitary: Ki te puta he pūkahukahu iti i roto i te repe pituitary i te pūtake o tō tātou roro , ka tīmata te whakaputa i te nui ake o te homoni e kiia nei ko te ACTH (Adrenocorticotropic hormone) . Ko tēnei homoni ACTH te mea e tohu ana i ngā repe adrenal kia whakaputa i te cortisol . Nō reira, ina piki te ACTH, ka piki aunoa hoki te hanga cortisol. Ka kiia hoki tēnei mate ko te Mate a Cushing .
• Ngā Pūkahukahu Repeure: I ētahi wā ka puta he pūkahukahu i te repe repeure, ka taea ai e tēnei te whakaputa tika i te nui o te cortisol.
• Ngā Puku Whānau: He tino onge, ka puta he puku i tētahi wāhi kāore i te hangaia te homoni ACTH, pērā i ngā pukahukahu , te repe tairoidi , te repe tairoi rānei, ā, ka tīmata te whakaputa ACTH.

Ka taea e ēnei pukupuku te mate pukupuku, te kore rānei.

He aha ngā tohu o tēnei mate?

Tērā pea ka rerekē ngā tohu i ia tangata, i ia tangata, engari kei reira ētahi tohu noa ka kitea ina kua horapa te mate. Me titiro tātou ki ēnei i roto i tētahi ripanga. Hei tāpiritanga, ka kite pea ētahi tāngata i ngā tohu totoro papura, māwhero rānei i runga i ō rātou puku, huha, ringa, me te uma. I te ngoikore haere o ngā wheua, ka pāngia pea rātou e te mamae o te tuara, e ngā rara whati rānei, ehara i te mea i te wā e piko ana, e hiki ana i ngā taumaha, engari i te wā e ara ake ana i te tūru. Mēnā ka pāngia ngā tamariki nohinohi e tēnei mate, ka tino puhoi tō rātou tipu, ā, ka momona hoki rātou.

Me pēhea te tautuhi a te tākuta i tēnei mate?

Tērā pea ka roa pea te wā e toro atu ai tō tākuta ki a koe kia whakaū ai i te mate. Tuatahi, ka tirotirohia koe e ia, ka pātai atu hoki i ētahi pātai ki a koe.

• He aha ō tohumate?
• Nōnahea koe i kite tuatahi ai i ēnei?
• He aha ngā rongoā e tangohia ana e koe? (Ina koa ko ngā steroids)
• Kei te kite koe i tētahi panonitanga i roto i tō hinengaro?

I runga i ēnei mōhiohio, mēnā e whakapaetia ana he mate a Cushing, ka tūtohu te tākuta i ētahi whakamātautau.

• Whakamātautau cortisol kore mimi 24-hāora: Ka ine i te taumata cortisol i roto i te mimi i kohia mō te wā 24-hāora.
• Whakamātautau pehi i te Dexamethasone: Ka hoatu he pire steroid iti te horopeta i te 11 i te pō pea, ā, ka mahia he whakamātautau toto i te ata e whai ake nei hei tirotiro i te nui o te cortisol e whakaputaina tonutia ana e te tinana.
• Te taumata cortisol huware i te pō: Ka ine i ngā taumata cortisol i roto i te tauira huware i tangohia i te pō.

Mena ka whakaūtia e ēnei whakamātautau kei a koe te mate Cushing, ko te mahi e whai ake nei ko te kimi i te pūtake . Hei mahi i tēnei, ka whakahaerehia pea e te tohunga ētahi atu whakamātautau. Hei tauira, ko ngā whakamātautau toto hei tirotiro i ngā taumata homoni ACTH, ko ngā matawai CT, MRI rānei.

He aha ngā maimoatanga mō tēnei?

Ko te tikanga maimoatanga e whakawhirinaki ana ki te take o tō mate.

• • Mena ko te rongoā steroid te take: Ka tīmata tō tākuta ki te whakaiti mārire i te horopeta o tō steroid i te mea kua whakahaeretia tō mate hauora kē atu (hei tauira, te huango, te rumatiki).

Ko te mea nui: Kaua e mutu ohorere te tango i ngā steroids me te kore he tohutohu a tō tākuta. Mā te mahi pera ka pā mai he pānga kino.

• Mena he pukupuku te pūtake: Me mahi pokanga pea hei tango i te pukupuku. I ētahi wā, ka taea te hoatu i te rongoā irahiko hei tāpiri atu ki te pokanga.
• Ngā maimoatanga kē atu: Mena kāore e angitu te pokanga, te rongoā irahiko rānei, ka taea te hoatu rongoā hei whakahaere i te hanga cortisol. Heoi anō, ka pāngia pea ēnei rongoā e ngā pānga taha, nō reira me tango i raro i te tirotiro a te tākuta.

Me pēhea te whakarerekē i te momo noho me te kai i te wā e rongoatia ana?

I a koe e rongoatia ana, mā te whakarerekē i tō momo noho me tō kai ka tino āwhina i a koe ki te whakahaere i ō tohumate.

• Kai i tētahi kai pai:
• Kai i ngā kai he nui te konupūmā me te huaora D. Ka ngoikore ngā wheua i tēnei āhuatanga. He pai te miraka, te miraka kawa, te tiihi, ngā huawhenua matomato, me ngā ika ririki (me ngā wheua).
• Whakaitihia ngā kai he nui te konutai me te hinu/ngako . Ka taea e ēnei te arahi ki te toto toto tiketike me te whakanui taumaha.
• Whakahaerehia te mamae:Mā ngā mahi pēnei i te kaukau wera, te mirimiri mārie, me te mahi whakakorikori tinana wai ka āwhina i te whakaiti i te mamae o ngā uaua.
• Hauora hinengaro: Ka taea e tēnei āhuatanga te whakapōrearea. Kōrero ki tō whānau me ō hoa mō tēnei. Tonoa tā rātou tautoko. Mena e tika ana, rapua he āwhina a tētahi kaiwhakatakoto whakaaro. Ka taea e koe te tono tohutohu ki tō tākuta.

Te Mate a Cushing, cortisol, steroids, homoni, toto toto tiketike, mate huka, ngoikore o te tinana, kanohi marama, piko o te kau, repe pituitary, repe adrenal, ngā tohu o te mate a Cushing, te maimoatanga o te mate a Cushing