Kei te mōhio koe ki ngā pukupuku neuroendocrine o te puku (GI NETs) ka puta i roto i tō pūnaha nakunaku?

Ka mamae tō puku i ētahi wā, ka pupuhi, ka puta mai rānei ētahi atu tohu e puta tonu mai ana? Kāore rānei he take e kitea ai tō taumaha? Ahakoa he tohu ēnei o ngā mate noa, tera pea he āhuatanga onge kei muri i ēnei āhuatanga me mōhio koe. I tēnei rā ka kōrero tātou mō tētahi o aua āhuatanga. Ko tōna ingoa ko Gastrointestinal Neuroendocrine Tumors , ko GI NETs rānei te poto. Kaua e manukanuka, ka kōrero māmā noa tātou mō tēnei.

He aha ēnei pukupuku neuroendocrine o te pūnaha nakunaku (GI NETs)?

He māmā noa iho, he momo mate pukupuku onge ngā GI NET e puta mai ana i roto i ngā pūtau neuroendocrine i roto i tō pūnaha nakunaku. Tērā pea kei te whakaaro koe he aha ngā pūtau neuroendocrine. He momo pūtau motuhake ēnei e hono ana i tō tātou pūnaha io me te pūnaha endocrine. He rite rātou ki ngā pokapū karere iti. Kei roto i ngā wāhi maha o ō tātou tinana ēnei pūtau, tae atu ki te pūnaha nakunaku.

He pūnaha roa, rite ki te ngongo tō ara kai e keri ana i te kai e kainga ana e tātou, e mimiti ana i ngā matūkai, ā, e whakakore ana i ngā para. Ko ēnei pukupuku 'GI NET' (i mua ko 'carcinoid tumors') ka puta i roto i tō whekau iti me te rectum . Heoi, ka taea hoki e rātou te puta i roto i tō puku, i tō apendiks, me tō esophagus. I ētahi wā, ka horapa ēnei pukupuku ki waho o te ara kai, pērā i tō ate .

Ko wai te mea tino pāngia e tēnei mate GI NET?

He mate tino onge tēnei. E ai ki ngā tatauranga, e 4 i roto i te 100,000 tāngata ka pāngia e tēnei mate. Ahakoa i roto i tētahi whenua pērā i te Hononga o Amerika, e 8,000 noa iho ngā pakeke ka kitea houtia kua pāngia e tēnei mate i ia tau.

Ko te tikanga ka pā tēnei mate ki te hunga i waenga i te 55 me te 65 tau te pakeke. Heoi, ka taea te whakawhanake i roto i ngā pakeke o ngā tau katoa. He nui ake te tūponotanga o te hunga mā ki te pāngia e tēnei mate i te hunga mangu. Waihoki, e whakaatu ana ngā raraunga he nui ake te tūponotanga o te hunga wāhine ki te pāngia e tēnei 'GI NET' i te hunga tāne.

He aha ngā tohu o te GI NET?

Anei te mea nui. Tērā pea ka kitea ēnei pukupuku i roto i te tinana o ētahi tāngata , kāore he tohu . I ētahi wā ka kitea noa iho i te wā e mahia ana he mahi pēnei i te 'matawai' mō tētahi atu take.

Heoi, ki te puta mai ngā tohu, ka rite pea ki ērā o ngā mate noa, iti ake te kino. Koia te take ka taea ai te kite i ētahi wā i te mutunga rawa. Tirohia mēnā e mōhio ana koe ki ēnei tohu:

• Mamae puku: He tohu pea tēnei kua purua ō whekau, nā te pukupuku GI NET pea.
• Korere:Te nekeneke pinepine o te puku. He tino kitea tēnei tohu i roto i te hunga whai mate e kiia nei ko te "Carcinoid Syndrome" (tētahi atu huinga tohu e pā ana ki te "NET"), i roto rānei i te hunga kua tangohia te puku o te puku, te wāhanga rānei o te puku mā te pokanga.
• Whakapairuaki me te ruaki: Ki te mau tonu te whakapairuaki me te ruaki, tera pea he tohu o tetahi mate kino.
• Te whakahekenga taumaha ohorere: Ki te tere tō whakahekenga taumaha me te kore e kai i tētahi kai iti, e whakakori tinana rānei, kāore rānei he take e kitea ana, he tohu noa tēnei o te GI NETs.
• Toto i roto i te tūtae: Mena he whero pouri, he parauri rānei tō tūtae, he tohu pea ēnei o te toto whekau.
• Te mate kiri māwhero: Ka huri te kiri me te mā o ō kanohi hei kōwhai.
• Ngenge: Ehara i te hiamoe noa iho tēnei. He tino ngenge tonu, kāore e taea te mahi i tetahi mea.

Kia maumahara, ko te kitenga noa i ēnei tohu ehara i te mea kei a koe te GI NET. Heoi, ki te mau tonu ēnei tohu, he mea nui kia toro atu koe ki te tākuta mō ētahi tohutohu.

He aha ngā take o te GI NET?

Ina hoki, kāore anō kia kitea e ngā kairangahau hauora he tino take mō ngā GI NET. Heoi, kua kitea e rātou he hononga tō te hunga he iti te waikawa o te puku (hypochlorhydria) ki tēnei mate.

Hei tāpiritanga, ko te hunga whai mate tuku iho me ētahi mate ka nui ake te mōrearea ki te whakawhanake i ngā GI NET. Ko ētahi o ēnei mate ko:

• Te maha o ngā neoplasia endocrine (MEN): E rua ngā momo o tēnei. Ko tētahi momo (MEN1) ka nui rawa te mahi a tō repe tairoiti, parathyroid, adrenal rānei, ka puta rānei he pukupuku. Ko tētahi atu momo (MEN2) ka nui rawa te mahi a tō repe repe taiora, pituitary, parathyroid rānei, ka puta rānei he pukupuku.
• Te mate a Von Hippel-Lindau: He tino onge hoki tēnei mate. Ka puta he pukupuku kore-matepukupuku (pai) ki ngā wāhanga rerekē o te tinana.
• Neurofibromatosis momo 1: He mate onge anō hoki tēnei. Ka puta he pukupuku ki te kiri me ngā io, ā, ka pā hoki ki ngā kanohi me ētahi atu wāhanga o te tinana.

Me pēhea te tautuhi a ngā tākuta i tēnei mate GI NET?

Mena kei a koe ngā tohu kua whakahuatia ake nei, mehemea rānei he whakapae mō tētahi atu take, ka whakahaerehia e ngā tākuta ngā whakamātautau maha.

• X-ray: Ka taea e tēnei te tango pikitia o ngā mea o roto i te tinana. Heoi, i ētahi wā he nui rawa, he iti rawa rānei te pukupuku GI NET, kāore e kitea i runga i te X-ray. Mēnā koinei te āhua, ka tūtohu pea tō tākuta i ētahi atu momo matawai.
• Matawai tomography rorohiko (CT):Ka whakamahia he rorohiko me tētahi raupapa hihi-X hei hanga i tētahi tirohanga toru-ahu (3D) o ō whekau me ō wheua. Ka taea e te matawai CT te whakaatu i ngā mea pēnei i te rahi o te pukupuku me te mea kua horapa ki te ate, ki ētahi atu wāhi rānei.
• Whakaahua aukume (MRI): Ka whakamahia e tēnei whakamātautau he aukume, he ngaru reo irirangi, me te rorohiko hei whakaputa pikitia tino mārama o ō whekau me ō wheua.
• Endoscopy: I tēnei tikanga, ka whakamahia e ngā tākuta he endoscope, he taputapu angiangi, he rite ki te ngongo me te rama me te kāmera i mua, hei tirotiro i roto i tō ara nakunaku o runga. Ka taea te whakauru i tēnei ngongo mā tō waha, mā tō pūkahukahu rānei. Ka whakamahia he colonoscope hei tirotiro i te wāhanga o raro o tō ara nakunaku.
• Te orooro endoscopic (EUS): Ka whakamahia he endoscope me ngā ngaru oro kaha-teitei hei tango pikitia o te pūnaha nakunaku. Ka whakaurua te endoscope mā te waha, mā te rectum rānei, ā, ka tukuna he ngaru oro ki te pito ki roto i te ara nakunaku. Ko ngā oro e pekepeke ana i ngā kiko i roto ka hanga pikitia e kiia nei ko ngā sonogram.
• Matawai Positron emission tomography (PET): Ka kitea e tēnei whakamātautau ngā pukupuku neuroendocrine mā te whakamahi i tētahi tae motuhake (he mea hanga motuhake hei kite i ngā pūtau pukupuku neuroendocrine).
• Biopsy: Koinei te whakamātautau tino whakamahia hei whakaū i te mate. I roto i tēnei, ka tangohia he wahi kiko iti mai i te wāhi whakapae, ka tirotirohia i raro i te karuārai hei tirotiro mēnā he pūtau matepukupuku kei roto.

He rerekē ngā momo pukupuku neuroendocrine?

Ae, ka whakamahia e ngā tākuta he pūnaha whakatauranga hei whakarōpū i ēnei pukupuku. Mā tēnei ka āwhina i a rātou ki te whakamahere i tā rātou maimoatanga. Ka whakatauhia te taumata o te pukupuku mā te tirotiro i ngā pūtau matepukupuku i raro i te karuārai. Ka tirohia e rātou te maha o ngā pūtau e wehewehe ana, te tere o tā rātou wehewehe, me te rite o ngā pūtau ki ngā pūtau matepukupuku i ngā pūtau hauora. Anei ngā taumata 'GI NET':

• Taumata 1 (pūtau iti): Ka tino pōturi te wehenga o ēnei pūtau. Ko te tikanga he tino pōturi te tipu o te pūtau.
• Taumata 2 (pukupuku taumata-waenga): He taurite te tere o te wehenga o ēnei pūtau.
• Taumata 3 (puku taumata teitei): Ka tere te wehewehe o ēnei pūtau, nō reira ka tere te tipu o te puku.

He aha ngā maimoatanga mō ngā pukupuku endocrine gastrointestinal (GI NETs)?

He maha ngā huarahi hei rongoā i ngā mate GI NET. Ka whiriwhiria e ngā tākuta te rongoā pai rawa atu māu i runga i ngā āhuatanga maha, tae atu ki te nui o tō mate pukupuku, ngā pānga taha pea mai i te rongoā, tō hauora whānui, me ō manakohanga whaiaro. He maha ngā kōwhiringa rongoā matua: te tirotiro kaha, te pokanga, me ngā maimoatanga hauora.

He aha te Aroturuki Kaha?

Mena he puhoi rawa te tipu o te puku, ā, he iti te mōrearea ki te horapa ki ētahi atu wāhanga o te tinana, ka tūtohu pea ngā tākuta i tētahi maimoatanga e kiia nei ko te "aroturukitanga kaha". Ko te tikanga o tēnei ko te tirotiro i a koe i ngā wā katoa , kaua e tīmata tonu i te maimoatanga nui.

• Ngā whakamātautau whakaahua pērā i te matawai CT.
• Ngā whakamātautau toto pēnei i te tatau toto katoa (CBC).
• Te whakamātautau tinana.

He aha ngā pokanga e mahia ana mō te GI NET?

Ko te momo pokanga e mahia ana mō te GI NET, ka whakawhirinaki ki ngā āhuatanga pēnei i te wāhi o te pukupuku me te horapa rānei ki ētahi atu wāhanga o te tinana.

He mea tino nui i mua i tō pokanga, kia mōhio tō tīma pokanga mēnā kei a koe te `(Carcinoid Syndrome)` (he āhuatanga e whakaatu ana i ngā tohu o te `neuroendocrine tumors`). Nā te mea, mēnā kei a koe te `(Carcinoid Syndrome)`, ka puta pea ngā raruraru i roto i te pokanga ka mōrearea te ora. Mēnā ka mōhio te taote pokanga ki tēnei, ka ngana ia ki te ārai i ēnei raruraru mā te hoatu ki a koe he rongoā motuhake i mua, i te wā, me muri i te pokanga.

Ko ētahi o ngā pokanga tino noa mō te GI NET ko:

• Te tango i te puku i te wāhanga kotahi: Ko te tango i tētahi wāhanga o tō puku.
• Te tango i te whekau iti: Ko te tango i te wāhanga o te whekau iti kei roto te pukupuku. Tērā pea ka mahi te taote pokanga i te anastomosis (te hono anō i ngā pito e rua o te whekau kua tapahia kia kotahi). Ko ngā pona lymph e tata ana ki te whekau iti ka tangohia, ā, ka tirohia i raro i te karuārai hei tirotiro mēnā he pūtau matepukupuku kei roto.
• Te tango i te āpitihanga: Ka taea e ngā taote pokanga te tango i tō āpitihanga mā te tapahi nui, mā te pokanga laparoscopic rānei (he tapahi iti me te kāmera e whakaurua ana).
• Hemicolectomy: I roto i tēnei, ka tangohia te taha matau, te taha maui rānei o te koroni, me ngā oko toto me ngā kōpū lymph e tata ana.
• Te tango i te puku o raro o mua: Ka tangohia e ngā taote pokanga tetahi wāhanga o tō pūkahukahu, engari ka waiho tonu tō pūkahukahu kia kore e neke. Mā tēnei ka taea e koe te neke noa i te puku.
• Te tango i te puku o te puku (APR): Ka tangohia e tēnei pokanga tō pūkahukahu, tō pūkahukahu, me tētahi wāhanga o tō kōpū . He maha ngā wā ka haere tahi tēnei pokanga me te colostomy. Ko te tikanga ka hangaia he kōhao mai i tō kōpū ki te mata o tō puku kia taea ai e ngā paru (ngā para nakunaku) te haere mā roto.
• Te tango i te ate: Ka tangohia e tēnei pokanga ngā GI NET kua horapa ki te ate.

He aha ngā raruraru, ngā pānga taha rānei o tēnei pokanga?

Ka pāngia pea koe e ngā pānga taha nui o ēnei pokanga katoa. I ētahi wā, me āwhina anō koe i te kāinga i a koe e ora ana. Pātai atu ki tō tākuta he aha ngā mea hei tumanakohia i muri i te pokanga motuhake e mahia ana ki a koe.

Ka pāngia tōku āhua noho e te pokanga GI NET?

Ae, tera pea ngā pānga taha . I te mea he maha ngā wā ka tangohia e ēnei pokanga tetahi wāhanga o tō pūnaha nakunaku, tera pea ka rerekē te āhua o tō kai me tō inu, tae atu ki te āhua o tō haerenga ki te wharepaku. Ka whakamāramahia e tō taote pokanga te pānga o te pokanga ki a koe, me tana mahi hei whakahaere i ngā raruraru nakunaku.

He aha atu ngā maimoatanga e wātea ana mō te GI NET?

I ētahi wā ka whakakotahi ngā tākuta i ēnei maimoatanga me te pokanga:

• Te rongoā matū: Ka whakamahia ngā momo rongoā rerekē i hangaia hei patu i ngā pūtau matepukupuku.
• Whakaora arotahi: Ka whakamahia e tēnei rongoā, ētahi atu matū rānei, ka whakaeke noa i ngā pūtau matepukupuku, me te kore e whara i ngā pūtau hauora noa.
• Ārai Mate: Ka whakamahia e tēnei te pūnaha ārai mate o tō tinana hei patu i ngā pūtau matepukupuku, hei aukati rānei i tō rātou tipu.
• Te rongoā irahiko: Ka whakamahia ngā hihi kaha o te pūngao hei patu i ngā pūtau matepukupuku, hei aukati rānei i tō rātou tipu.
• Ngā momo rite o te somatostatin: He momo hangai ēnei o te homoni somatostatin. Ka mahi tō somatostatin mā te aukati i tō tinana kia kaua e hanga i te nui rawa o te homoni.

He aha ngā pānga taha, ngā raruraru rānei o ēnei maimoatanga?

He rerekē te pānga o ia maimoatanga ki ia tangata. Nō reira, he mea nui kia kōrero mārama koe ki tō tākuta mō ngā painga me ngā pānga taha o ia maimoatanga. Mā tēnei koe e āwhina ki te mārama ki te pānga o ia maimoatanga ki a koe. Ka tūtohu tō tākuta i ngā maimoatanga i runga i tō hauora whānui me ō hiahia whaiaro.

Ka taea te ārai i ngā pukupuku endocrine o te puku?

Engari, kāore anō kia kitea he huarahi hei ārai i ngā GI NET i tēnei wā . Heoi, kua kitea e ngā kairangahau hauora he hononga i waenga i ētahi mate tuku iho me/ranei ngā āhuatanga hauora me te mōrearea o te whakawhanake i ngā pukupuku neuroendocrine. Kōrero ki tō tākuta mō tō hītori hauora me te hītori hauora o tō whānau. Tērā pea ka tūtohu ia i ngā whakamātautau motuhake hei kite i ngā tohu tōmua o ngā GI NET, kia taea ai te hopu me te rongoā wawe i ngā pukupuku.

Mena kei a au tēnei āhuatanga, he aha taku e tumanako ai?

Ko tō matapae mate ka whakawhirinaki ki te wā e kitea ai te mate pukupuku, ā, ka tīmata te maimoatanga. Tata ki te 97% o te hunga e whiwhi maimoatanga ana i mua i te horapa o te mate pukupuku ki ētahi atu wāhanga o te tinana ka ora.E rima tau i muri i te tātaritanga. Mena kua horapa te pukupuku ki ngā kiko tata, ki ngā kōpū lymph rānei, ka heke te reiti oranga mō ngā tau e rima ki te 95%. Tata ki te 67% o te hunga whai GI NETs kua horapa ki waho o te ara nakunaku e ora tonu ana i muri i ngā tau e rima i muri i te tātaritanga.

Ka taea e te GI NET te hoki mai. I runga i te rahi, te momo, me te wāhi o te puku, me whai whakamātautau aroturuki auau koe. Hei tauira, ka tūtohu pea tō tākuta kia mahia he matawai CT kotahi i te tau mō ngā tau tuatahi e toru i muri i te maimoatanga me te whakamātautau tinana i ia tau. Pātai atu ki tō tākuta mō ngā wā tirotiro me ngā whakamātautau e pā ana ki tō āhua.

Me pēhea taku tiaki i ahau anō?

Mena he pukupuku neuroendocrine tōu, tera pea me pokanga koe. I te nuinga o te wā ka whakamahia e ngā taote pokanga ngā tapahi tuwhera, he nui ake i te pokanga laparoscopic. Ko te tikanga me noho koe ki te hōhipera mō ētahi rā, kātahi ka ora i te kāinga mō ētahi wiki.

Āhea ahau me haere ki te Rūma Ohotata?

Tērā pea he wā tirotiro auau tāu hei tirotiro mēnā kua hoki mai anō tō mate pukupuku. Pātai atu ki tō taote pokanga he aha ngā tohu i muri i te pokanga hei tohu pea mō tētahi mate kino. Mēnā ka pāngia koe e tētahi o ngā tohu e whai ake nei, me rapu tonu koe i te awhina hauora:

• Te uaua ohorere ki te manawa.
• Mena he nui ake te kirika i te 38.3 nekehanga Celsius (100.4 nekehanga Fahrenheit).
• Mena he nui te mamae, kāore rānei e taea te whakahaere mā te whakamahi i ō rongoā whakamamae.
• Mena he pūkahukahu kakariki, he kakara kino e puta mai ana i te patunga pokanga, ina koa mena ka wera te wāhi huri noa i te patunga ki te pā atu, ki te whero rawa rānei.
• Mena kei te ruaki tonu koe, kei te pāngia rānei koe e te mate korere.

Ka taea e te pukupuku neuroendocrine gastrointestinal (GI NET) te huri i te ora. Nā te mea he maha ngā tāngata e pāngia ana e tēnei mate me pokanga hei tango i tētahi wāhanga, i te katoa rānei o tā rātou pūnaha nakunaku. Tērā pea ka huri tō pokanga i te āhua o tō kai, tō inu, me tō haere ki te wharepaku. E mōhio ana tō rōpū hauora ehara i te mea ngāwari te urutau ki ēnei huringa. Mena he pātai, he āwangawanga rānei āu, kōrerotia ki tō tākuta. Ka mārama rātou ki tō āhuatanga, ā, ka āwhina i a koe ki te kimi otinga.

He aha ngā mea tino nui hei ako mā tātou i tēnei pūrākau?

• He momo pukupuku matepukupuku tino onge te 'GI NET', engari he mea nui kia mōhio koe ki tēnei.
• Tērā pea ka pāngia ētahi tāngata e ēnei āhuatanga , engari kia tūpato ki ngā tohu pēnei i te mamae o te puku, te korere, me te ngaronga taumaha ā-kore e hiahiatia ana.
• Tukua ēnei kia tupu.Kāore anō kia kitea te tino take, engari tera pea ētahi āhuatanga tuku iho e whai wāhi ana.
• He maha ngā whakamātautau hei tautuhi i ngā mate, pērā i te `CT scan`, te `MRI`, te `Endoscopy`, me te `Biopsy`.
• Ko ngā kōwhiringa maimoatanga ko te pokanga, te chemotherapy, me te radiation therapy . Mā tō tākuta e whakatau ko tēhea maimoatanga te mea pai mōu.
• Mā te tautuhi wawe me te tīmatanga o te maimoatanga ka nui ake te tūponotanga o te ora.
• Mena he ruarua, he pātai rānei āu mō tēnei mea, kaua e wehi ki te kōrero ki tō tākuta . Kei reira rātou hei āwhina i a koe.

` GI NET, Ngā Puku Neuroendocrine Gastrointestinal, Matepukupuku, Matepukupuku Whekau, Ngā Puku Neuroendocrine, Pūnaha Nakunaku, Ngā Tohu