Kei te āwangawanga koe mō te tipu o tāu tamaiti? Tērā pea he ngoikore o te homoni tipu (GHD) tēnei?

Kei te puhoi ake te tipu o tāu tamaiti i ētahi atu tamariki o tōna tau? Ki tō whakaaro rānei he poto ake tōna āhua i tōna tau? He mea noa ki ngā mātua te āwangawanga mō ēnei mea i ētahi wā. Heoi, kāore pea i te ngāwari i ngā wā katoa. I tēnei rā ka kōrero tātou mō tētahi āhuatanga ka puta ake i te hinengaro i ēnei wā, engari kāore i te tino noa. Ko te 'Growth Hormone Deficiency', e kiia ana hoki ko te 'GHD'.

He aha tēnei 'Growth Hormone Deficiency (GHD)'? Kia mārama tātou!

He whakarāpopototanga noa iho, ko te GHD he āhuatanga e kore ai e puta te nui o te homoni tipu (GH) e hiahiatia ana e te repe iti i roto i tō tātou roro, arā, te repe pituitary, he mea nui mō te tipu o te tinana. E kīia ana hoki tēnei e ētahi ko te "pituitary dwarfism". Ka pā pea tēnei āhuatanga ki ngā pēpi, ki ngā tamariki, me ngā pakeke. He poto ake i ō rātou tau ngā tamariki whai GHD, engari he noa pea ō rātou tinana kē atu.

Kei te mōhio koe, he rite ngā homoni ki ngā karere matū i roto i ō tātou tinana. Ka haere rātou i roto i te toto, ka tohutohu i ō tātou whekau, uaua, me ētahi atu kiko ki te aha me mahi, me te wā hoki me mahi ai.

He iti nei, engari he mea nui rawa atu te 'Pituitary Gland'. Kei te pūtake o te roro, kei raro i te 'Hypothalamus'. E rua ngā wāhanga matua: ko te 'Anterior Lobe' me te 'Posterior Lobe'. Ko te 'Anterior Lobe' tēnei e whakaputa ana i te 'Growth Hormone (GH)' me ētahi atu homoni e 8 pea.

I ētahi wā, ka pāngia pea te hunga whai GHD e te mate e kiia nei ko te hypopituitarism, he ngoikoretanga o ētahi atu homoni e hangaia ana e te repe pituitary. Kei roto i ēnei homoni:

• `Homona Antidiuretic (ADH, Vasopressin rānei)`
• 'Homoni whakaoho-pūmua'
• 'Homoni Whakapūngao'
• Te homoni whakaohooho tairoi (TSH)
• `Homoni Adrenocorticotrophic (ACTH)`

Nā, he aha te mahi a tēnei 'Homoni Tipu'?

He mea tino nui te homoni tipu (GH) mō te tipu o ngā tamariki. He pānga ki ngā wāhanga maha o te tinana. He mea nui mō te tipu noa, te kaha o te uaua me te wheua, me te tohatoha o te ngako tinana .

I muri i te kati o ngā pereti tipu (epiphyses) i roto i ō tātou wheua, arā, ka mutu tā tātou tipu roa, kāore te GH e āwhina i a tātou kia tipu roa. Heoi anō, e hiahia tonu ana ō tātou tinana ki te GH. I a tātou e pakeke haere ana, ka āwhina te GH ki te pupuri i te hanganga tinana noa, ka pupuri i te rere pai o te pākia o te tinana, ā, ka āwhina hoki ki te pupuri i ngā taumata huka toto .

Nō reira, ka taea e koe te kite ahakoa he tamariki koe, he taiohi, he pakeke rānei, ki te kore e nui te homoni tipu i roto i tō tinana, ka pā ki a koe i ngā huarahi rerekē i runga i tō tau. I roto i ngā tamariki me ngā taiohi, ka taea e te GHD te kore e tipu tika. I roto i ngā pakeke, ka pā mai ngā raruraru pēnei i te pikinga o te ngako tinana me te taumata huka toto tiketike.

He rerekē ngā momo o te 'Growth Hormone Deficiency (GHD)'?

Āe, e toru ngā momo matua o te `GHD`:

• GHD whānau: He mate tēnei e kitea ana i te whānautanga. Ka puta pea i te whakarerekētanga ira, i te raruraru rānei ki te hanganga o te roro o te pēpi.
• GHD i Whiwhi: Ka puta tēnei i te kino o te repe pituitary i muri mai i te oranga. Ka taea e ngā tamariki me ngā pakeke te whakawhanake i te GHD i tēnei ara.
• GHD koretake: I roto i te rongoā, ko te tikanga o te "koretake" ko te kore e mōhiotia te take . I ētahi wā o te GHD, kāore e kitea he take motuhake.

Ka whakarōpūtia hoki te GHD e ai ki te tau tīmatanga, nā te mea he rerekē ngā tohu me ngā tikanga tātaritanga i runga i te mea ka tīmata i te tamaiti, i te pakeke rānei.

E pēhea te noa o te ingoa o tēnei mate ko te 'GHD'?

He tino onge te korenga o te homoni tipu (GHD). I te nuinga o te wā, ka pāngia e te GHD te kotahi i roto i te 4,000 ki te kotahi i roto i te 10,000 tamariki. He onge anō hoki te GHD e pāngia ana e te pakeke, e pāngia ana te kotahi i roto i te 10,000 tāngata.

He aha ngā tohu o te 'Growth Hormone Deficiency (GHD)'?

Ka rerekē ngā tohu o te GHD i runga i te tau e pāngia ai koe e te mate.

Ngā tohu o te GHD i roto i ngā pēpi me ngā tamariki

Ina pāngia ngā pēpi me ngā tamariki e te GHD, ka pōturi te tipu o ō rātou tinana. Ko te tohu matua ko te piki haere o te teitei i ia tau i muri i te toru o ngā rā whānau o te tamaiti . Ko te tikanga he iti iho i te 1.4 inihi te roa o te tinana i ia tau.

Ko ētahi atu āhuatanga ko:

• He kanohi e āhua taitamariki ake ana i tōna tau.
• Te ngoikore o te tupu o ngā makawe me ngā maikuku.
• Te whakaroa o te puta o ngā niho.
• Te pakeketanga kua roa .
• Te iti o te huka toto (hypoglycemia) i roto i ngā pēpi me ngā tamariki nohinohi.
• He tino iti te ure o ngā pēpi tāne whānau hou (‘Micropenis’).

Ngā tohu o te GHD e tīmata ana i te pakeketanga

Ko ngā tohu o te GHD e tīmata ana i te pakeketanga ka uaua ake te kite. Ko ēnei tohu ko:

• Te whakaaro o te kore o te harikoa me te oranga ngākau.
• Te manukanuka me/ranei te pouri.
• Te ngoikore o te kaha tinana.
• Te nui haere o te ngako e putu ana, inā koa i te taha o te puku .
• Te ngoikore o te uaua.
• Ka taea e te iti o te matotoru o te wheua te arahi ki ngā āhuatanga pēnei i te osteoporosis.
• Ka taea e te ātete ki te insulin te arahi ki te mate huka momo 2.
• Ka piki ake te mōrearea o te mate ngakau mēnā ka nui haere ngā taumata o te LDL-cholesterol me ngā triglycerides.

He aha ngā take o tēnei āhuatanga e kiia nei ko te `GHD`?

Ka rerekē pea ngā take o te GHD i runga i te tau i tīmata ai te mate. I ētahi wā, kāore e kitea he take (idiopathic).

Ngā Take o te GHD Whakatupu

Ko te GHD whānau ka puta mai i te whakarerekētanga ira . I ētahi wā ka hono atu tēnei ki ngā raruraru o te hanganga o te roro, ki ngā hapa rānei i waenganui o te mata (hei tauira, te waha ngatata, te niho kotahi o te karu matua).

Kua tautuhia e ngā kaipūtaiao ētahi huringa ira e puta ai te GHD. Ko ētahi o ēnei:

• Te ngoikore o te homoni tipu motuhake momo IA: Nā tēnei whakarerekētanga ira ka puhoi te tipu i te wā o te kukune, ā, he iti rawa te pēpi i te wā i whānau ai. I te tīmatanga ka pai te urupare a ēnei tāngata ki te maimoatanga homoni tipu hangai (GH), engari i muri mai ka puta he paturopi hei ārai i te homoni. Ko te hua o tēnei ka pōturi te tipu me te poto rawa o te roa o te pakeke.
• Te ngoikore o te homoni tipu motuhake momo IB: He rite tēnei ki te momo IA, engari he GH tūturu kei roto i te tinana o ēnei pēpi i te whānautanga. Ka aro atu hoki rātou ki te maimoatanga GH horihori puta noa i ō rātou oranga.
• Te ngoikore o te homoni tipu momo II: He tino iti ngā taumata GH o ēnei tāngata, ā, tera pea he rerekē ngā taumata o te ngaronga teitei. Ko te korenga o te tipu ka kitea i te tīmatanga o te tamarikitanga, i waenganui rānei o te tamarikitanga. Tata ki te haurua o ēnei tāngata he repe pituitary kāore i te tino whanake (Pituitary Hypoplasia).
• Te ngoikore o te homoni tipu momo III: Pērā i te momo II, he tino iti ngā taumata GH o ēnei tāngata, ā, ka rerekē pea ngā taumata o te whakapōturi. Ko te korenga o te tipu ka kitea i te tīmatanga o te tamarikitanga, i waenganui rānei o te tamarikitanga. Tērā pea he ngoikore te pūnaha ārai mate, ā, he maha ngā mate pāwera.

Ka rerekē pea ngā tauira tuku iho o tēnei momo ngoikore o te homoni tipu i ia whakatipuranga ki ia whakatipuranga.

Ngā Take o te GHD i Whiwhihia

Ko te GHD, e puta ake ana i ngā tau tōmuri, ka puta mai i te kino o te repe pituitary. Nā tēnei kino ka ngaro te kaha o te repe ki te whakaputa me te huna i te homoni tipu. Ka taea e ngā tamariki me ngā pakeke te whakawhanake i te GHD i tēnei ara.

Ka pakaru pea te repe pituitary i ngā āhuatanga, i ngā huihuinga rānei pēnei i:

• Ko te adenoma pituitary (he pukupuku ehara i te matepukupuku).
• Te rongoā irahiko ki te repe pituitary me ōna rohe e karapoti ana.
• Te whara nui o te upoko, te 'Whara Roro Mamae (TBI)' rānei.
• Te ngoikore o te rere o te toto ki te repe pituitary.
• He kino tūpono, he kino rānei e kore e taea te karo i te wā e pokanga ana te roro, e tangohia ana rānei te pituitary adenoma.
• 'Te Mate Pukupuku o te Pūnaha Io Matua'.
• Ngā mate e horapa ana i roto i te tinana, pērā i te histiocytosis pūtau Langerhans, te sarcoidosis, me te mate kohi.
• Ka taea e ngā pukupuku i roto i te hypothalamus te pēhanga ki runga i te repe pituitary.

Me pēhea te tātaritanga a ā mātou tākuta i tēnei mate 'GHD'?

He maha ngā wā ka kitea te GHD i roto i ngā tamariki e rua tau te pakeke. Ko te tuatahi kei te tata ki te 5 tau te pakeke, arā, te wā ka tīmata ngā tamariki ki te kura . Nā te mea ka taea e ngā mātua te whakataurite i te teitei o tā rātou tamaiti ki te teitei o ētahi atu tamariki i roto i tā rātou akomanga. Ko te awhe tau tuarua kei waenganui i te 10-13 tau mō ngā kōtiro me te 12-16 tau mō ngā tama . Koinei ngā tau ka tīmata te pakeketanga. Ka taea e te pakeketanga whakaroa te whakaara ake i ngā whakapae mō te GHD.

Ko te mea tino nui hei tātaritanga i te GHD i roto i ngā tamariki ko te pikinga o te tipu . Koinei te roa o te tipu o te tamaiti. I te nuinga o te wā ka whai i tētahi tauira te tipu. Mena ka aroturukitia te tipu mō te wā e 6 ki te 12 marama, ā, kei roto i te awhe noa i taua wā, he iti noa te tūponotanga o tētahi raruraru tipu.

Ka tīmata te GHD i te pakeketanga, ā, he uaua ki te tautuhi i te mate nā te mea he koretake ōna tohu, ā, he rite tonu ki ngā mea noa. Ka uaua pea te tautuhi i te mate.

He aha ngā whakamātautau e mahia ana ki ngā tamariki hei kite i te `GHD'?

Ka arotakehia e te tākuta o tāu tamaiti tōna hītori hauora me ngā tūtohi tipu hei rapu i ngā tohu o te korenga o te tipu, ngā āhuatanga mōrearea mō te GHD, me ētahi atu āhuatanga ka pā ki te tipu.

Ko ētahi atu āhuatanga hauora ka pā ki te tipu ko:

• Hypothyroidism (te repe tairoiti kāore i te mahi pai).
• Te pakeketanga kua roa.
• Mate Celiac.
• Te kore kai tōtika.

Nā te mea he tino rerekē ngā taumata o te homoni tipu i roto i ō tātou toto i te roanga o te rā, kāore e taea e te whakamātautau toto anake te whakatau i te korenga o te GH. Nō reira, ka tono pea te tākuta o tō tamaiti i ngā whakamātautau pēnei hei whakaū i te GHD me/ranei te whakakore i ētahi atu āhuatanga ka pā ki te tipu:

• Hiko-X: Ka taea te whakahaere i tētahi hihi-X o te ringa hei aromatawai i te whanaketanga o te wheua (te pakeketanga o te wheua) me te pūmanawa tipu.
• Ngā whakamātautau toto me ētahi atu whakamātautau taiwhanga:Ka taea e ētahi whakamātautau toto te āwhina ki te whakakore i ētahi atu āhuatanga e pā ana ki te tipu, ki te āwhina rānei ki te tautuhi i te GHD. Ko ngā whakamātautau toto motuhake ko te insulin-like growth factor-1 (IGF-1) me te insulin-like growth factor binding protein-3 (IGFBP-3).
• Whakamātautau Whakaoho i te Homoni Tipu: Koinei te whakamātautau matua e whakamahia ana e ngā tākuta hei tātaritanga i te GHD. I roto i tēnei whakamātautau, ka hoatu he rongoā ki tāu tamaiti hei whakaoho i te repe pituitary kia tukuna te GH. Kātahi ka tangohia e te tākuta he tauira toto ka ine i te taumata GH. Mena kāore ngā hua o te whakamātautau toto e whakaatu ana kua piki te taumata GH ki te taumata e tumanakohia ana, ko te tikanga kāore te repe pituitary e whakaputa ana i te GH i te nui.
• Whakaahua Āhua Aukume (MRI): Tērā pea ka tonoa e te tākuta o tāu tamaiti he MRI o te upoko. Ka āwhina tēnei ki te whakatau i te pūtake o te GHD mā te rapu i ngā raruraru o te repe pituitary, o te roro rānei.

He aha ngā whakamātautau e mahia ana ki ngā pakeke hei kite i te `GHD`?

Ko te whakamātautau tino whakamahia hei tautuhi i te GHD i roto i ngā pakeke ko te Whakamātautau Manawanui ki te Insulin . Ko te insulin he homoni e hangaia ana e te repe taiaki.

I tēnei whakamātautau, ka werohia koe e te tākuta ki te insulin horihori hei whakaheke i te taumata huka toto. Kātahi ka tangohia he tauira toto, ka ine i te nui o te homoni tipu i roto i ō toto.

Ina iti te taumata o te huka toto (hypoglycemia), ka tukuna te homoni tipu. Mena ka whakaatuhia e ō whakamātautau toto he iti iho te taumata o tō homoni tipu i te mea e tumanakohia ana i roto i te whakamātautau manawanui insulin, ka whakaū tēnei i te mate GHD.

Tērā pea ētahi atu whakamātautau:

• 'Whakamātautau whakaohooho Glucagon'
• `Whakamātautau whakaohooho Macimorelin`
• 'Whakamātautau whakaohooho arginin'
• `Whakamātautau whakaohooho Clonidine`

Me pēhea te rongoā i te 'Growth Hormone Deficiency (GHD)'?

Ko te rongoā mō te GHD i roto i ngā tamariki me ngā pakeke ko te werohanga i te homoni tipu hangai (Recombinant Human Growth Hormone) . Ka taea ēnei te hoatu ki te kāinga. He maha ngā wā me werohanga te hunga whai GHD i ia rā .

He roa te maimoatanga homoni tipu hangai, ā, i ētahi wā ka roa mō ngā tau. He mea nui kia toro atu koe ki tō tākuta i ia wā, kia kite ai mēnā kei te pai te mahi a te maimoatanga, me te hiahia hoki kia whakarerekētia te horopeta.

Mena he ngoikore ōu, tō tamaiti rānei i roto i ētahi atu homoni pituitary, me rongoā anō hoki koe hei whakatika i aua ngoikoretanga.

Ngā pānga taha o te maimoatanga 'GHD'

He onge ngā pānga taha ngawari, āhua rānei o ngā werohanga homoni tipu mō te maimoatanga GHD. Heoi, kei roto pea i ēnei:

• Te mamae o te upoko.
• Te mamae o ngā uaua, te mamae rānei o ngā hononga.
• Te hypothyroidism ngawari.
• Te pupuhi o ngā ringa me ngā waewae.
• Te pikinga o te piko o te tuaiwi i roto i te hunga e pāngia ana e te scoliosis.

Tērā pea ka puta mai ngā pānga taha onge engari he kino:

• Te mamae nui o te upoko e haere tahi ana me ngā raruraru tirohanga.
• Te Dysplasia o te hope (te piri hē o te wheua huha ki te wheua hope).
• Pancreatitis (mumura o te pancreas).

Mena kei a koe tētahi o ēnei tohu, he mea nui kia kōrero tonu atu koe ki tō tākuta . Me whakarerekē pea te horopeta o tō rongoā.

He aha ngā āhuatanga mōrearea e pā ana ki te whakawhanaketanga o te 'GHD'?

Engari, kāore e taea te ārai i te nuinga o ngā take o te GHD. Heoi anō, tera pea ētahi āhuatanga mōrearea ka whakanui ake i te tūponotanga ka pāngia koe, tō tamaiti rānei e te GHD kua whiwhi. Kei roto i ēnei ko:

• Te whiwhi maimoatanga matepukupuku i mua i te ekenga ki te teitei pakeke.
• Te whiwhi maimoatanga irahiko ki te mahunga, ki te roro rānei.
• Te Whakamārama i te Tinana Katoa.
• He pokanga ki te roro, inā koa te wāhanga pokapū o te roro kei reira te repe pituitary.

Mena ka pā tētahi o ēnei āhuatanga mōrearea ki a koe, ki tāu tamaiti rānei, he mea nui kia mōhio koe ki ngā tohu o te GHD, ā, kia kōrero ki tō tākuta mōna.

He aha te matapae mō te GHD?

Mō ngā tamariki whai GHD, ko te wawe o te rongoā i te mate, ko te nui ake o te tūponotanga ka tata te tipu o te tamaiti ki te teitei pakeke noa . Ko te nuinga o ngā tamariki e piki ake ana i te whā inihi, neke atu rānei, i te tau tuatahi o te rongoā. E toru inihi, neke atu rānei, ka piki ake i roto i ngā tau e rua e whai ake nei. Whai muri i tēnā, ka puhoi te tere tipu.

Ko te hunga e pāngia ana e te GHD i te wā pakeke, ki te tika te rongoā, he pai te tirohanga whānui, ā, ka taea e rātou te noho hauora.

He aha ngā raruraru ka pā mai i te GHD?

Ki te kore e rongoātia te GHD i roto i ngā tamariki, ka taea e ia te arahi ki te poto o te tinana me te roa o te pakeketanga .

Ahakoa te maimoatanga tika, ka nui ake te mōrearea o te hunga pakeke kua pāngia e te GHD ki te mate ngakau me te whiu . Ka taea te whakaiti i tēnei mōrearea mā roto i ngā tikanga hauora pēnei i te kai i te kai taurite me te whakakori tinana i ngā wā katoa.

Ko te hunga e pāngia ana e te GHD i te pakeketanga ka nui ake te tūponotanga ki te pāngia e te osteoporosis. Ko te tikanga he nui ake te tūponotanga ka whati ngā wheua i ngā whara iti, i ngā hinganga rānei. Hei whakaiti i ēnei tūponotanga, he mea nui kia kai i ngā kai whai kiko i te konupūmā me te tango i ngā tāpiringa huaora D e ai ki te taunakitanga a tō tākuta.

Āhea ahau me toro atu ki te tākuta mō te GHD?

He maha ngā take e puhoi ai te tipu o ngā tamariki, e poto ake ai hoki i te tikanga. I ētahi wā, he mea noa, he wā poto noa iho te puhoi o te tipu. Hei tauira, ina tata mai te pakeketanga. Mena kei te āwangawanga koe mō te tere tipu o tāu tamaiti, tirohia he tākuta endocrinologist tamariki, he tākuta rānei . Ka taea e rātou te āwhina i a koe ki te whakatau mena he mea hei āwangawanga mō te tere tipu o tāu tamaiti.

Mena he pakeke koe, ā, kei a koe ngā tohu o te GHD, kōrero ki tō tākuta.

Mena kua tāpaetia koe, tāu tamaiti rānei kei te mate GHD, me toro atu koe ki tō tākuta i ia wā, kia mōhio ai kei te tika te mahi a te maimoatanga .

Ki te kite koe i tētahi whakaroa tipu o tāu tamaiti, he mea nui kia kōrero wawe atu ki tō tākuta. Ahakoa kāore pea ko te GHD te take, he mea tika kia tirohia ngā huringa āwangawanga. Ki te kitea wawetia te hunga whai GHD, he pai ake tō rātou tirohanga, ā, ka taea e rātou te noho hauora. Ki te mea he pātai āu mō te tipu o tāu tamaiti, kaua e wehi ki te pātai atu ki tō tākuta. Kei konei rātou hei āwhina.

Karere Whakamutunga mō te Tango ki te Kāinga

Nō reira, kua mārama pea koe ki te tikanga o te 'Growth Hormone Deficiency (GHD)' me tōna pānga ki ngā tamariki me ngā pakeke. Ko te mea nui kia kaua e mataku, kia tere tonu te toro atu ki te tākuta mēnā he āwangawanga āu . Mā te tātaritanga wawe me te maimoatanga tika, ka taea e te nuinga o te hunga whai 'GHD' te ora angitu, te ora hauora. Mēnā he āwangawanga āu mō te whanaketanga o tāu tamaiti, mō tō ake hauora rānei, kāore i roa rawa te kōrero ki te tākuta mō tēnei.

` Te Kore o te Homoni Tipu, GHD, Te Kore o te Homoni Tipu, Repe Pituitary, Tipu o te Tamaiti, Poto, Ngā Raru Homoni, GH