Kia ako tātou mō te Homoni Tipu Tangata (HGH) i roto i ngā kupu māmā noa iho.

Kei te whakaaro koe kāore tō tamaiti e tipu teitei ana pērā i tōna teitei e tika ana? Kāore rānei koe e ngenge tonu ana, e ngoikore ana hoki? Tērā pea ko te take o tēnei he karere matū iti kei roto i tō tinana. Ko tētahi o ngā homoni he mea nui mō te tipu o tō tātou tinana me te maha atu o ngā mea e kiia ana ko te homoni tipu tangata . Ka kiia e mātou ko te HGH (Human Growth Hormone) te whakarapopototanga. Ka kiia hoki e ētahi ko te somatotropin . Nō reira, i tēnei rā, me kōrero taipitopito tātou mō tēnei HGH, he tino māmā noa iho.

He aha te HGH? Me pēhea te whakaputanga i roto i tō tātou tinana?

He kupu ngāwari noa iho, he homoni tūturu te HGH e hangaia ana e ō tātou tinana. Ka hangaia e tētahi repe iti kei raro noa iho i tō tātou roro, he rite te rahi ki tētahi wheua iti. Ka kiia e tātou ko te repe pituitary . Ka pā tēnei homoni HGH ki ngā wāhanga maha o tō tātou tinana. He mea nui rawa atu mō te tipu o ngā tamariki . He nui te āwhina a te HGH i ngā mea pēnei i te whakanui ake i te roa o tāu tamaiti me te whakapakari ake i ōna wheua.

Heoi, ina pakeke tātou, arā, i muri i te kati o ngā pereti tipu i roto i ō tātou wheua (epiphyses), kāore te HGH e whakanui ake i a tātou. Engari ehara i te mea koinā anake ngā mahi a te HGH. Ahakoa kua pakeke tātou, ka āwhina te HGH ki te pupuri i te hanganga noa o tō tātou tinana, me te pupuri i te rere tika o te pākia o te tinana . Ko tēnei pākia te mea e huri ai te kai e kainga ana e tātou hei pūngao. Ka āwhina hoki te HGH ki te pupuri i ngā taumata huka toto (glucose) ki tētahi taumata.

He matū ngā homoni i roto i ō tātou tinana. He rite rātou ki ngā karere. Ka haere i roto i te toto, ka tohutohu i ō tātou whekau, uaua, me ētahi atu kiko he aha te mea hei mahi, me te wā hoki hei mahi. Neke atu i te 50 o ēnei homoni kei roto i ō tātou tinana!

Kei te pūtake o te roro te repe pituitary i kōrerotia e au i mua ake nei, i raro i te hypothalamus . He maha ngā mea e whakahaeretia ana e tēnei hypothalamus, pērā i te toto totoka, te tere o te manawa, te pāmahana o te tinana, me te nakunaku. Nō reira, ko tēnei hypothalamus te mea e kī ana ki te repe pituitary kia tukuna te HGH. Ko te homoni e āwhina ana i tēnā ko te GHRH (growth hormone-releasing hormone) . Waihoki, ka puta mai tētahi atu homoni (somatostatin) i te hypothalamus hei aukati i te tukunga o te HGH. Koinei te whakahaeretanga o te HGH.

I ētahi wā ka whakamahia e ngā tākuta te HGH hangai hei rongoā i ētahi mate. Engari kia maumahara, kaua rawa e whakamahi i te HGH hangai me te kore he whakahaunga a te tākuta.

He aha ngā āhuatanga e pā ana ki te whakaputanga o te HGH?

Ko te tikanga, ka tukuna e tō tātou repe pituitary te HGH i roto i ngā rahinga iti puta noa i te rā, e kiia nei ko ngā pulses . Ko te nuinga o tēnei e whakahaerehia ana e ngā homoni e rua mai i te hypothalamus, ko te GHRH me te somatostatin.

Ehara i te mea koinā anake, engari kei roto hoki ētahi atu homoni. Hei tauira,Ka whakaitihia te hanga HGH e te insulin-like growth factor 1 (IGF-1), ko ngā homoni pērā i te thyroxine , te glucocorticoids , me te ghrelin ka whakanui ake i te tukunga HGH.

Ko te IGF-1, e tukuna ana e tō tātou ate, he hua nui o te mahi a te HGH. Ko tēnei IGF-1 te mea e whakahaere ana i te nui rawa o te HGH. Ara, ka puta te IGF-1 i te HGH, ā, ka whakaitihia anō te hanga o te HGH e te IGF-1 e puta ana. He rite ki te huringa.

I roto i te tangata hauora, ka aukatia te tukunga HGH e ngā taumata huka toto tiketike (hyperglycemia) . Hei tāpiri, ka whakaohokia te tukunga HGH e ngā mea pēnei i te moe, te ahotea, te korikori tinana, te iti o te huka toto (hypoglycemia) , me ngā waikawa amino .

He aha ngā mahi matua a te homoni HGH?

E rua ngā mahi matua a te HGH:

1. Te whakaoho i te tipu (ina koa i roto i ngā tamariki)

2. Te pānga ki te pākia o te tinana (te huarahi e huri ai tātou i te kai e kainga ana e tātou hei pūngao)

HGH me te tipu

Ka āwhina te HGH i ngā kiko me ngā okana katoa o te tinana kia tipu. Engari he mea rongonui mō te āwhina i te tipu o te kiriuhi me te wheua . He mea nui rawa tēnei i te wā taiohi. Ka whiwhi ngā pūtau e kiia nei ko ngā chondrocytes i roto i te kiriuhi me ngā osteoblast i roto i ngā wheua i ngā tohu mai i te HGH kia wehea, kia nui ake hoki te tipu.

Heoi, e ai ki taku kōrero i mua ake nei, kāore te HGH e whakanui ake i te teitei i muri i te kati o ngā pereti tipu (epiphyses) i roto i ngā wheua o te tamaiti. Engari, ka āwhina te HGH ki te pupuri i te hanganga tinana noa puta noa i te oranga.

HGH me te pākia o te tinana

Ko te pākia o te kai te tukanga matū e huri ai te kai e kainga ana e tātou hei pūngao. Me whai pūngao ia pūtau o te tinana kia pai ai te mahi.

Ko te pānga o te HGH ki te pākia o te tinana mā te whakanui ake i te hanga o te IGF-1, e whakarerekē ana i te āhua o tana pānga ki ngā pūtau o tō tātou tinana. Ko te IGF-1 he homoni he rite te hanganga ki te insulin . Ko te insulin he homoni nui e hangaia ana e tō tātou repeure e whakaiti ana i ngā taumata huka toto (glucose) . Kei a IGF-1 anō te kaha ki te whakaheke i te huka toto.

I te nuinga o te wā, ka āta whakahaeretia e ō tātou tinana ngā taumata huka toto. Ko te huka toto, te momo huka matua rānei, i roto i ō tātou toto. Ka whiwhi tātou i tēnei mai i ngā kai warowaihā e kainga ana e tātou. Ko tēnei huka te mea e whakarato ana i te pūngao mō ō tātou whekau, uaua, me te pūnaha io.

Ko te insulin te homoni matua e whakaheke ana i te huka toto ina teitei. Ā, ko te homoni glucagon ka whakanui ake i te huka toto ina iti. Heoi, ko te HGH te tikanga ka whakanui ake i te huka toto ina iti. Heoi,Ki te nui rawa te pikinga o te HGH i roto i tō tinana, ka taea e ia te whakararuraru i te mahi a te insulin, ā, ka piki ake ngā taumata huka toto.

Ka tino whakanuia ake koe e te HGH?

Ae, ka taea e te HGH te whakanui ake i te teitei o ngā tamariki. Engari i mua noa iho i te hononga o ngā pereti tipu i roto i ō rātou wheua. Kāore e taea e te HGH te whakanui ake i a koe i muri i te hononga o ngā pereti tipu. Engari, i muri i tō ekenga ki tō teitei teitei rawa, ka āwhina te HGH ki te pupuri i te hanganga me te pākia o tō tinana.

He aha ngā taumata noa o te HGH?

E ai ki taku kōrero i mua ake nei, ka tukuna e te repe pituitary te HGH i roto i ngā wā poto puta noa i te rā. Ka rerekē ēnei taumata i runga i te wā o te rā, te tau, me te ira tangata. Nō reira, kāore e tino whai hua te whakamātautau toto kotahi hei ine i te HGH mō te tautuhi i tētahi mate. Engari, ka tirohia e ngā tākuta ngā taumata HGH mā roto i ngā whakamātautau motuhake (ngā whakamātautau whakaohooho, whakamātautau pehi rānei).

Ko ngā taumata HGH noa e whai ake nei:

• Nga tane pakeke: 0.4 ki te 10 nanograms mo ia mira (ng/mL)
• Wahine pakeke: 1 ki te 14 nanograms ia miririta (ng/mL)
• Tamariki: 10 ki te 50 nanograms mo ia mira (ng/mL)

Engari kia maumahara, ka rerekē pea ēnei uara i ia taiwhanga. Nō reira, whakaritea ki te awhe noa i runga i tō pūrongo taiwhanga. Mēnā he āwangawanga āu, me kōrero ki tō tākuta.

Ka aha mēnā ka heke te taumata o te HGH? (Te ngoikore o te homoni tipu)

Ina iti iho ngā taumata HGH i te mea noa, ka kiia tēnei ko te ngoikore o te homoni tipu . Ko te tikanga ka puta tēnei i tētahi raruraru, i tētahi kino rānei ki te repe pituitary. Ka taea e tēnei te arahi ki tētahi āhuatanga e kiia nei ko te hypopituitarism . Ko te tikanga tēnei ka whakaitihia tētahi, neke atu rānei o ngā homoni e hangaia ana e te repe pituitary. He homoni anō hoki te HGH ka pāngia pēnei.

He rerekē ngā pānga o tēnei ngoikoretanga HGH ki ngā pakeke me ngā tamariki.

Mena ka heke te taumata o te HGH i roto i ngā pakeke:

Mena ka heke te taumata HGH o te pakeke, ka puta pea ēnei raruraru:

• Te hekenga o te harikoa me te ngākau māhaki ki te ao.
• Te nui haere o te ngako o te tinana.
• Te pikinga ake o te mōrearea o te mate ngakau.
• Te ngoikore o te ngākau, ngā uaua me ngā wheua.

I roto i ngā pakeke, ka puta pea tēnei mate i te pituitary adenoma (ehara tēnei i te mate pukupuku, engari he pukupuku) i te kino rānei o te repe pituitary/hypothalamus.

Mena he iti te HGH o ngā tamariki:

Ki te heke te taumata HGH o te tamaiti, ka āraia te tipu. Ko te tohu matua ko te pikinga puhoi o te teitei i muri i te toru o ngā rā whānau o te tamaiti. Arā, he iti iho i te 1.4 inihi ia tau. Hei tauira, ki te mea he poto ake te āhua o tāu tamaiti i ngā tamariki kē atu o te akomanga, me āwangawanga koe.

Hei tāpiri, tera pea ka pāngia te tamaiti he ngoikore te HGH e ngā tohu pēnei i:

• He kanohi e āhua taitamariki rawa atu ana i tōna tau.
• Te ngoikore o te tipu o te makawe.
• Te pakeketanga kua roa.

Ka whānau mai pea ngā tamariki me tēnei mate. I ētahi wā, kāore i te mōhiotia te pūtake (idiopathic), he ira tuku iho pea, he kino rānei ki te repe pituitary i te wā e hapu ana, i te whānautanga rānei. I ētahi wā, ka pā mai anō hoki ki te kino ki te repe pituitary, ki te hypothalamus rānei i muri mai i te oranga.

Ka aha mēnā ka piki ake ngā taumata HGH?

Ko te acromegaly te mate matua e pā ana ki te nui ake o te HGH i te mea noa. He rerekē hoki te pānga o tēnei ki ngā pakeke me ngā tamariki. He mate tino onge.

Te Acromegaly i roto i ngā pakeke

Ko ngā pakeke e pangia ana e te acromegaly ka nui haere, ka pupuhi rānei ō rātou ringa me ō rātou waewae , me ngā panoni hoki o te āhua o te kanohi .

Tērā pea he matotoru ake ō rātou wheua, he nui ake hoki ō rātou whekau o roto. He nui ake te tūponotanga ka pāngia rātou e ngā mate pēnei i te toto toto tiketike , te mate huka momo 2, me te mate ngakau. Neke atu i te 99% o ngā take acromegaly e puta mai ana i ngā pukupuku kore-matepukupuku i roto i te repe pituitary e kiia nei ko ngā pituitary adenomas . Ka taea e ēnei pukupuku te whakaputa i te nui rawa o te HGH. Ko te acromegaly te mea tino kitea i muri i te pakeketanga waenga, i muri i te otinga o te tipu. Nō reira, kāore ngā pakeke e pāngia ana e te acromegaly e tipu roa ake. Engari, ka matotoru pea ō rātou wheua.

Te Acromegaly (Gigantism) i roto i ngā tamariki

He tino onge te kitea o ngā taumata HGH teitei i roto i ngā tamariki i mua i te ekenga ki tō rātou teitei katoa. Ka nui rawa te tipu o ngā wheua roa i tēnei, ka hua ake he tamariki teitei rawa. Ka kiia tēnei mate ko te acromegaly taiohi . I ētahi wā ka kiia ko te gigantism . Ki te kore e rongoatia, ka tipu pea ēnei tamariki ki te whitu putu te roa, ki te roa ake rānei. Tērā pea ka pāngia rātou e ngā tohu pēnei i te ngenge, te roa o te pakeketanga, me te ānini.

Ko te nuinga o te wā ka puta mai tēnei i te adenoma pituitary.

Me pēhea te ine i ngā taumata HGH?

Mena kei a koe, kei tāu tamaiti rānei ngā tohu e tohu ana he raruraru kei a rātou e pā ana ki te HGH, ka tonoa pea e tō tākuta ētahi whakamātautau toto hei tirotiro i ō taumata HGH.

E ai ki taku kōrero i mua ake nei, ka tukuna e te repe pituitary te HGH ki roto i te toto i te awatea, ā, i ētahi wā i te pō. Nō reira, he uaua ki te mārama tika i te āhuatanga mā te tango toto me te tirotiro i te HGH kotahi noa iho.

Nō reira, he maha ngā wā ka whakamahia e ngā tākuta ngā tikanga e kīia nei ko ngā whakamātautau whakaoho me te pehi i te homoni tipu hei tautuhi i ngā āhuatanga i puta mai i te korenga, i te taikaha rānei o te HGH.

Hei tāpiritanga, ka taea te whakamātautau toto hei tirotiro i ngā taumata o te IGF-1 (insulin-like growth factor 1) .

Me pēhea te whakamahi i te HGH hei rongoā?

Kua whakaaetia e te Tari Kai me te Rongoā o te Hononga o Amerika (FDA) te HGH hangai hei rongoā i ētahi mate. Ka taea anake te tiki i tēnei HGH hangai mā te whakahaunga a te tākuta, ā, ka hoatu hei werohanga.

Ka tohua te HGH ki ngā tamariki mō ēnei āhuatanga e whai ake nei:

• Te korenga o te homoni tipu.
• Ngā āhuatanga e hua ai te poto o te tinana, pērā i te mate tākihi mau tonu , te mate Turner , me te mate Prader-Willi .

Ka tohua te HGH mō ngā pakeke mō ēnei āhuatanga e whai ake nei:

• Te korenga o te homoni tipu.
• Te ngaronga o te papatipu uaua nā te HIV .
• Te mate puku poto .

He mea tino nui: Kaua rawa e whakamahi i te HGH hangai ki te kore e tohua e tō tākuta.

He aha ngā pānga taha o te HGH hangai?

Tērā pea ka puta ētahi pānga taha ina whakamahia te HGH hangai hei rongoā. Ko ēnei:

• Te mate pūwero carpal (he uaua kua kopikopiko i te ringaringa).
• Te pikinga ake o te ātete ki te insulin me/te mate huka momo 2 rānei.
• Te pupuhi o ngā ringa me ngā waewae (edema) .
• Te mamae o ngā hononga me ngā uaua.
• Te whakanui ake i te kiko o te ū i roto i ngā tāne (gynecomastia) .
• Te pikinga ake o te mōrearea ki ētahi momo mate pukupuku.

Kāore anō kia rawaka ngā mōhiohio a ngā kairangahau mō ngā pānga roa o te maimoatanga HGH hangai.

Āhea ahau me toro atu ki te tākuta mō ngā taumata HGH?

Mena kei a koe, kei tāu tamaiti rānei ngā tohu e pā ana ki te korenga, te taikaha rānei o te HGH (hei tauira, te puhoi o te tipu, te rahi haere o ngā peka), me toro atu koe ki tō tākuta.

Mena kei te rongoatia kētia koe mō tētahi āhuatanga rerekē o ngā taumata HGH, he mea tino nui kia kite tonu koe i tō tākuta kia mōhio ai kei te tika te mahi a tō maimoatanga.

He homoni kaha te HGH, he mea nui mō ngā tukanga nui o roto i tō tātou tinana. I ētahi wā ka nui rawa, ka iti rawa rānei te hanga a te repe pituitary. Mena kei a koe, kei tō tamaiti rānei tētahi o ēnei tohu, he pai ake te kōrero ki te tākuta. Kei reira rātou hei āwhina i a koe.

Karere Whakamutunga mō te Tango ki te Kāinga

Āe, i kōrero nui tātou mō te HGH i tēnei rā, kāore? Me whakarāpopoto tātou:

• He homoni tino nui te HGH mō tō tātou tipu, inā koa i te wā tamarikitanga, me te whakahaere hoki i ngā mahi pākia o te tinana.
• Ka whakaputaina tēnei e te repe pituitary i roto i tō tātou roro.
• Ki te heke te taumata o te HGH, tera pea ka pōturi te tipu o ngā tamariki, ā, ka pāngia hoki ngā pakeke e ngā raruraru hauora maha.
• Ki te piki ake ngā taumata HGH, ka puta pea ngā āhuatanga pēnei i te acromegaly.I roto i ngā tamariki, ka puta pea tēnei hei gigantism, arā, ko te tipu teitei rawa atu.
• Ki te whakapae koe kei a koe, kei tāu tamaiti rānei te raruraru o te HGH, kaua e mangere ki te rapu tohutohu hauora.
• Kaua rawa e whakamahi i te HGH hangai me te kore he whakahaunga a te tākuta.

Kia maumahara, ko te kaupapa o ēnei katoa he whakaako i a koe. Mena he āwangawanga hauora āu, ko tō tākuta anake te mea ka taea te whakarato i te otinga pai rawa atu. Kia ora tonu koe!

` Te Homoni Tipu Tangata, HGH, Repe Pituitary, Tipu Tamariki, Te Pikinga Teitei, Te Pūnaha Whakaora, Te Tauritekore o ngā Homoni