Kāore anō kia heke tō toto toto ahakoa kua rongoāhia? Me ako tātou mō te hyperaldosteronism.

Kei te whakaaro koe i ētahi wā, 'He aha rawa te take kāore e heke ai taku toto toto ahakoa te rongoā?'? He rite tonu te raruraru o ētahi tāngata. He wā anō ka uaua ki te whakahaere i ō rātou toto toto, ahakoa kua tangohia he rongoā. I ngā wā pēnei, me whakaaro tātou mēnā he take kei raro iho. I tēnei rā, ka kōrero tātou mō tētahi mate e uaua ana ki te tautuhi i ētahi wā, engari ka taea te whakaora mēnā ka rongoatia tika. Ko te hyperaldosteronism tēnā.

He aha te Hyperaldosteronism?

Ki te kī ngāwari, ko te hyperaldosteronism te wā e nui rawa ai te homoni e whakaputaina ana e ō repe adrenal e kiia nei ko te aldosterone . Whakaarohia pēnei, he rite te aldosterone ki tētahi miihini iti e whakahaere ana i tō tātou toto toto. Ka āwhina i te pupuri i tō tātou toto toto ki te taumata tika mā te whakahaere i ngā taumata o te pāhare pāporo me te konutai i roto i ō tātou tinana.

Tērā pea kei te whakaaro koe, 'He aha ēnei repe adrenal?' He wāhanga ēnei o tā tātou pūnaha endocrine . He rite ki ngā wheketere iti e whakaputa ana i ngā momo homoni e hiahiatia ana e ō tātou tinana kia mahi ai i ia rā. E rua ā tātou repe adrenal, kei runga tonu i ō tātou whatukuhu, he rite ki te taupoki.

He aha ngā momo o te hyperaldosteronism?

E rua ngā momo matua o te hyperaldosteronism.

1. Te Hyperaldosteronism Tuatahi: Ka kiia tēnei ko te mate a Conn . Ko te mea e tupu ana i konei ko te he o ō repe adrenal, ka nui rawa te aldosterone e whakaputaina ana e rātou. Whakaarohia he raruraru kei roto i tētahi wheketere, ā, he nui rawa ngā mea e whakaputaina ana e rātou.

2. Te Hyperaldosteronism Tuarua: Ehara tēnei i te raruraru o ngā repe adrenal. He raruraru kei tētahi atu wāhi o tō tinana e whakaohooho ana i ngā repe adrenal, ā, ka tīmata te whakaputa i te nui ake o te aldosterone. Ko te tikanga tēnei kei te mahi roa te wheketere nā te awe o waho.

Ahakoa pēhea, ko te mutunga iho ko te pikinga o ngā taumata aldosterone o roto i tō toto, ka puta te toto toto tiketike (hypertension) me te hekenga o ngā taumata pāhare pāporo o roto i tō toto. Ko tēnei hekenga o te pāhare pāporo ka kiia ko te hypokalemia .

Ko wai te hunga e tino pāngia ana e tēnei mate? He pēhea te noa o tōna pānga?

Ko te hyperaldosteronism te mea tino kitea i roto i te hunga i waenga i te 30 me te 50 tau te pakeke.Waihoki, he paku noa ake te kitea o tēnei mate i roto i ngā wāhine i ngā tāne.

He uaua ki ngā kairangahau te kī tika i te auau o tēnei mate, nā te mea he hē te tātaritanga i ētahi wā. Engari e kī ana ētahi rangahau kei waenganui i te 5% me te 10% o te hunga he toto toto tiketike te mate pea i te hyperaldosteronism tuatahi. E ai ki ngā tohunga, tae atu ki te 25% o te hunga he toto toto tiketike ātete ki te rongoā te mate pea i tēnei mate. Nō reira, ehara i te mea onge, tika?

He aha ngā tohu o te Hyperaldosteronism?

Ka rerekē ngā tohu o te hyperaldosteronism i ia tangata, i ia tangata, i runga i te kaha o te mate. Tērā pea kāore he tohu o ētahi tāngata, inā koa kāore i te tino kino te mate.

Heoi, ko te tohu matua me te tohu tino kitea o tēnei mate ko te toto toto tiketike (hypertension) , inā koa ko te toto toto tiketike e kore e taea te whakahaere ahakoa te rongoā.

Hei tāpiritanga, ki te pāngia koe e ētahi atu tohu, he maha ngā wā ka puta mai i te toto toto tiketike ngawari ki te kino me/ranei te iti o ngā taumata pāhare pāporo i roto i te toto (hypokalemia).

Ngā tohu ka puta mai i te toto toto tiketike (hypertension):

• Ngā mamae o te upoko
• Pōuriuri
• Ngā huringa tirohanga
• Te uaua ki te manawa

Ngā tohu ka puta mai i te iti o te pāhare pāporo i roto i te toto (hypokalemia):

• Te ngoikore o te uaua - I ētahi wā kino, ka puta pea he āhuatanga e rite ana ki te pararutiki rangitahi.
• Te wiri, te oho rānei o te uaua (Te pupuhi o te uaua)
• Te wiri me te māuiui
• Ngenge
• Te matewai nui (e kiia ana tēnei he polydipsia)
• Te mimi pinepine

Nā, kua mārama koe, nā te mea he rite tonu ētahi o ēnei tohu ki ētahi atu mate, kua roa rawa pea te wā ki te kite i tēnei.

He aha te take o tēnei?

He rerekē ngā take o te hyperaldosteronism i runga i te mea he tuatahi, he tuarua rānei. Me titiro tātou me pēhea.

Ngā Take o te Hyperaldosteronism Tuatahi

E ai ki taku kōrero i mua, ko te Primary Hyperaldosteronism he raruraru kei roto i ō repe adrenal, ka nui rawa te aldosterone e whakaputaina ana e rātou.

Ko te tino take o tēnei ko ngā pukupuku kore-matepukupuku e kiia nei ko ngā adenoma adrenal e puta mai ana i roto i ngā repe adrenal . He pukupuku iti ēnei, kāore he kino, engari ka taea e rātou te whakaputa nui rawa o te homoni aldosterone.

Hei tāpiritanga, he maha atu anō ngā take onge :

• Te hyperplasia adrenal kotahi-taha - Ko te tikanga ka pupuhi, ka nui, ka nui ake ngā homoni e whakaputaina ana e te repe adrenal kotahi anake i tetahi taha.
• Ngā mate pukupuku adrenocortical e whakaputa ana i te aldosterone - He pukupuku matepukupuku ēnei. Heoi, he tino onge.
• Te hyperaldosteronism whānau momo 1 - He mate tēnei e tukuna iho ana i ngā mātua ki ngā tamariki.

Ngā Take o te Hyperaldosteronism Tuarua

Ko te tino take o te hyperaldosteronism tuarua ko te hekenga o te nui o te toto e tae atu ana ki ō whatukuhu .

Hei mārama ki te āhua o tēnei, me mōhio koe ko te homoni aldosterone he wāhanga o tētahi mekameka matatini o ngā homoni e whakahaere ana i tō tātou toto toto. Whakaarohia he rite ki tētahi tauhohenga mekameka.

Ko te ingoa o tēnei pūnaha ko te pūnaha renin-angiotensin-aldosterone . Koinei te āhua o tana mahi:

1. Ina rongo tō tinana i te toto toto iti, i te konutai rānei i roto i tō toto, ka tukuna e ō whatukuhu he whākōkī e kiia nei ko te renin .

2. Ka huri tēnei renin i tētahi matū e kiia nei ko te angiotensinogen (he matū matua mō te angiotensin) i hangaia e tō ate hei angiotensin I. (He homoni te Angiotensin e whakawhāiti ana i ō tātou uaua toto.)

3. Muri iho, ka huri tēnei angiotensin I hei angiotensin II .

4. Hei whakamutunga, ko te angiotensin II tēnei e whakawhāiti ana i ngā oko toto, ā, e whakaoho ana i ngā repe adrenal ki te tuku i te homoni aldosterone .

Whakaarohia, mēnā ka heke te nui o te toto e rere ana ki ngā whatukuhu, ā, ka whakaaro ngā whatukuhu, 'Āe, kua heke taku toto toto.' Kātahi ka whakahohehia e rātou tēnei pūnaha renin-angiotensin-aldosterone. Ko te mutunga iho, ka piki ake te taumata o te aldosterone i roto i te tinana, ahakoa kāore i te tino hiahiatia.

Ngā take ka whakaiti i te rere o te toto ki ngā whatukuhu, ka puta ai te hyperaldosteronism tuaruaAnei ētahi:

• Te mate ārai uaua whatukuhu - he rite ki te paipa wai kua purua.
• Te toto toto tiketike o te whatukuhu
• Ngā āhuatanga e kohia ai te wai i roto i te tinana (edema) , hei tauira:
• Te ngoikore o te ngākau
• Te mate ate
• He mate tākihi te mate nephrotic .

Me pēhea te tautuhi i tēnei?

I te nuinga o te wā ka tātaritatia e te tākuta te hyperaldosteronism mā roto i ngā whakamātautau toto . Heoi, he maha ngā tāngata kāore i te tātaritatia ki te mate nā te mea he maha atu ngā take me ngā āhuatanga mōrearea mō te toto toto tiketike.

Ko ētahi tohu noa e whakaatu ana kei a koe te hyperaldosteronism ko:

• Te toto toto tiketike e ātete ana ki te rongoā.
• Anei ngā hua o tō pūrongo whakamātautau toto electrolyte :
• He iti te teitei o te taumata konutai (hypernatremia) .
• He iti te taumata konupora (hypomagnesemia) .
• Waihoki, he iti ngā taumata pāhare pāporo (hypokalemia) .

Mena kei te whakapae tō tākuta kei te pāngia koe e te hyperaldosteronism i runga i ēnei tohu me ngā āhuatanga, ka tonoa pea e ia kia rua ngā whakamātautau toto motuhake: te Plasma Renin Concentration (PRC) te Plasma Renin Activity (PRA) rānei.

• Mena kei a koe te Primary Hyperaldosteronism , ka iti iho ō taumata PRC me PRA i te tikanga.
• Mena he hyperaldosteronism tuarua tāu, ka teitei ake ēnei taumata i te mea noa.

Hei tāpiritanga, me whai whakamātautau pehi aldosterone pea koe. Ko tēnei whakamātautau he hoatu i tētahi nui o te konutai (tote) mā te waha, mā te werohanga tote (IV) rānei mō tētahi wā. Kātahi ka kohia ō tauira mimi mō te wā 24-hāora, ā, ka inehia te nui o te aldosterone i roto i taua mimi i roto i te taiwhanga.

Mena ka whakaūtia e ēnei whakamātautau kei a koe te hyperaldosteronism, ka tonoa pea e tō tākuta ētahi atu whakamātautau hei kimi i te pūtake. Hei tauira, he matawai CT (matawai tomography rorohiko) hei tirotiro mena he pukupuku ehara i te matepukupuku te take o te hyperaldosteronism.Tērā pea ka tonoa koe kia whakamātauria he whakaahua .

He aha ngā maimoatanga mō tēnei?

Ko te maimoatanga mō te hyperaldosteronism e whakawhirinaki ana ki te take, engari ko te whāinga matua ko te whakahaere i tō toto toto .

• Mō te hyperaldosteronism tuatahi, he mate i puta mai i te pukupuku repe adrenal, ka tūtohu ngā tākuta kia tangohia te pukupuku i roto i te pokanga . Heoi, i ētahi wā, ka taea te rongoā i ēnei pukupuku mā te rongoā anake. Ahakoa i muri i te pokanga, tera pea kei te piki tonu te toto toto, nō reira me tango pea e koe he rongoā hei whakahaere.

• Ka rongoatia te hyperaldosteronism tuarua mā te whakahaere i tō toto toto mā te whakamahi i ngā rongoā, me te rongoā anō hoki i te pūtake (hei tauira, te mate manawa) .

He maha ngā momo rongoā hei āwhina i te hyperaldosteronism:

• Spironolactone (Spironolactone - Aldactone®)
• Eplerenone (Eplerenone - Inspra®)
• Amiloride (Amiloride - Midamor®)

Kotahi te mea hei maumahara māu, ko te whakamahinga roa o ngā rongoā aukati-aldosterone, pērā i te Spironolactone , ka pāngia pea ngā tāne e ētahi pānga taha. Hei tauira, ka pāngia pea ngā tāne e te ngoikore o te ure me te gynecomastia . Nō reira, he mea nui kia kōrero koe ki tō tākuta mō te rongoā pai rawa atu māu, te roa o te wā e tangohia ai, me ngā pānga taha.

Ka taea te ārai i tēnei?

Ina hoki, i te nuinga o te wā, kāore he mea ka taea e koe te mahi hei ārai i tēnei āhuatanga o te hyperaldosteronism. Nā te mea ka puta mai i ngā huringa o ngā tukanga o roto o tō tātou tinana. Heoi, ka taea e koe te pupuri i tō hauora whānui mā te whai i tētahi momo noho hauora, te kai i tētahi kai taurite, me te whakakori tinana.

He aha te matapae mō tēnei āhuatanga?

Ko te matapae mō te hyperaldosteronism e whakawhirinaki ana ki te take.

• Ki te kitea wawetia, ā, ki te rongoatia tika te hyperaldosteronism tuatahi , he pai te hua . Mēnā ka tangohia he pukupuku, ka taea te whakahaere i te mate.
• Te Hyperaldosteronism TuaruaKo te heke mai o te mate e whakawhirinaki ana ki te pai o te whakahaere i te mate hauora matua (hei tauira, te mate manawa, te mate ate).

Ko ngā raruraru matua ka puta mai i te hyperaldosteronism ko ngā raruraru cardiovascular i puta mai i te toto toto tiketike. Kei roto i ēnei:

• Te fibrillation atrial - he pākia o te ngakau e te koretake.
• Te hypertrophy o te ventricular maui - te matotoru o ngā pakitara o te ruma maui o te ngākau.
• Te whakaekenga o te ngakau
• Whiu

Koia te mea nui kia tere te tautuhi i tēnei mate, kia tika ai hoki te maimoatanga.

Āhea ahau me toro atu ki te tākuta?

Mena kua tāpaetia koe he hyperaldosteronism, me toro atu koe ki tō tākuta i ia wā, kia mōhio ai koe kei te pai te mahi a te rongoā e tohua ana ki a koe . He mea nui anō hoki kia whai i ngā tohutohu a tō tākuta.

Ki te puta he tohu hou ki a koe, ki te kite rānei koe i tētahi huringa o ngā tohu o nāianei , me whakamōhio tonu atu ki tō tākuta.

Ko te mea nui, ki te mea he toto toto tiketike ātete koe ki ngā rongoā, kōrero ki tō tākuta mō ō āwangawanga, pēnei i te, "Tērā pea he hyperaldosteronism tōku?" Ka taea e ia te arotake i tō āhua me te taunaki i ngā whakamātautau e tika ana.

Kia maumahara, he maha ngā take o te toto toto tiketike. Ko te hyperaldosteronism tētahi o aua take. Ko te rongo pai he mate ka taea te rongoā.

Karere Tangohia ki te Kāinga

Āe, ko tāku tumanako kua mārama ake koe ki tā tātou i kōrero ai, arā, te Hyperaldosteronism. Anei ētahi mea hei maumahara māu:

• Ko te Hyperaldosteronism te whakaputanga nui rawa o te homoni aldosterone e ngā repe adrenal.
• Ka taea e tēnei te hua ake te toto toto tiketike (hypotension) me te iti o te pāhare pāporo i roto i te toto (hypokalemia) .
• E rua ngā momo matua: Ko te Tuatahi ( he raruraru ki ngā repe adrenal) me te Tuarua (he whakaohooho i te repe adrenal nā tetahi raruraru i hea atu).
• Mena he toto toto tiketike tōu, ā, kāore e taea te whakahaere e te rongoā , me tūpato koe ki tēnei.
• Ka kitea tēnei mā roto i ngā whakamātautau toto .
• Ko te maimoatanga he whakahaere i te toto totoka me te rongoā i te pūtake .
• Mena ka kitea wawetia, ka rongoatia hoki, ka taea te whakatutuki i ngā hua pai .

Mēnā he pātai anō āu mō tēnei, tēnā pātai atu ki tō tākuta. Kia ora tonu koe!

` Hyperaldosteronism, Hyperaldosteronism, Aldosterone, Toto toto tiketike, toto toto tiketike, Pāhare pākawa, Repe adrenal, Mate a Conn