Kei te matewai tonu koe, ā, kei te mimi nui hoki? Me kōrero tātou mō te Nephrogenic Diabetes Insipidus.

Kei te matewai anō hoki koe i te rā roa? Ahakoa te nui o te wai e inuhia ana e koe, kei te ahua tonu kāore i te rawaka? Me mimi tonu koe i ngā wā maha, i te nui hoki? Tērā pea kei te whakaaro koe he mea noa tēnei, kei te whakaaro rānei koe he mate huka. Heoi anō, he tohu pea tēnei o tētahi mate hauora onge e kiia nei ko te 'Nephrogenic Diabetes Insipidus'. Me kōrero ngāwari tātou mō tēnei, i roto i tētahi huarahi e mārama ai koe.

He aha te Mate Huka Insipidus Nephrogenic?

Ki te whakarapopoto, ko te mate huka insipidus nephrogenic he āhuatanga e kore ai e taea e ō whatukuhu te whakahaere tika i te nui o te wai i roto i tō tinana. Ka whakaputahia e ō tātou tinana he homoni e kiia nei ko te Antidiuretic Hormone, ko te ADH rānei hei whakarapopototanga. Ka karangatia hoki e ētahi ko te Vasopressin. Ko tēnei homoni, ko te ADH, ka "kōrero" ki ō tātou whatukuhu te nui o te wai hei whakaputa ki roto i te mimi me te nui hei pupuri ki roto i te tinana.

Kāore ngā whatukuhu o te tangata e pangia ana e te mate huka insipidus nephrogenic e aro tika ki tēnei homoni ADH. Ara, ahakoa ka tukuna e te homoni ADH he tohu kia "pupuri wai, kia whakaiti hoki i te mimi," kāore ngā whatukuhu e whakarongo ki a ia. Ko te mea ka tupu, ka nui ake te mimi e whakaputaina ana e ngā whatukuhu i te mea e tika ana. Ka tere pea tēnei, i ētahi wā he morearea, ka arahi ki te matewai, arā, te kore wai.

He pēhea te noa o tēnei āhuatanga?

Kāore i te tino mārama ngā kaipūtaiao e hia ngā tāngata e pāngia ana e te mate huka insipidus nephrogenic, engari e whakapono ana rātou he tino onge tēnei mate. Arā, ehara i te mate e pāngia ana e te katoa.

He rerekē ngā momo mate huka insipidus?

Āe, e whā ngā momo mate huka insipidus. Kia tirohia tātou he aha ēnei:

• Te Mate Huka Waenga o te Mate Huka: Ka puta tēnei ina he kino te repe pituitary, te hypothalamus rānei i roto i tō roro. Koinei ngā wāhanga o tō roro e whakaputa ana, e penapena ana, e tuku ana hoki i te homoni ADH. Mā tēnei kino ka kore tō tinana e whakahaere i te ADH i te āhua noa.
• Mate Huka Insipidus Nephrogenic: I roto i tēnei momo mate huka e kōrerohia ana e tātou i tēnei rā, kāore e taea e ngā whatukuhu te aro tika ki te homoni ADH. Ahakoa kei reira te homoni ADH, te āhua nei kāore ngā whatukuhu e aro ki tēnei.
• Mate Huka Insipidus Dipsogenic: E kiia ana ko te 'Primary Polydipsia', ka puta mai i te hapa o te pūnaha whakahaere matewai i roto i tō hypothalamus. Ka meinga koe kia tino matewai, kia hiahia ki te inu wai i ngā wā katoa , me te mimi nui.
• Te Mate Huka Insipidus o te Hāputanga: Ka puta noa tēnei i te wā e hapū ana. I ētahi wā ka pakaru te homoni ADH i te whākōkī i hangaia e te whenua whānau. Ka ngaro atu tēnei i muri i te whānautanga o te pēpi.

He aha te rerekētanga i waenga i te Mate Huka Insipidus Nephrogenic me te Mate Huka Mellitus?

He take tino nui tēnei e pōhēhē ana te tini tāngata. Ina rongo tātou i te kupu "mate huka," ka whakaaro tātou ki te huka, arā, ko te mate huka. Heoi, ahakoa he rite ētahi o ngā tohu o te mate huka insipidus nephrogenic me te mate huka (pērā i te mimi nui me te matewai nui), he tino rerekē ēnei mate e rua.

He mate tino noa te mate huka mellitus. Nā te korenga o te homoni insulin, nā te kore rānei o te tinana e whakamahi tika i te insulin, ka piki ake te huka toto. Heoi, ko te mate huka insipidus nephrogenic he raruraru ka puta ina kore ngā whatukuhu e aro ki te homoni ADH, ā, kāore he pānga ki ngā taumata huka toto . Nō reira, he pai ake kia kaua e whakapoauau i ngā mea e rua, tika?

He aha ngā take o te mate huka insipidus nephrogenic?

Ko ō tātou whatukuhu te kawenga mō te tātari i te toto me te tango i ngā para me te wai tāpiri mai i te tinana hei mimi. Mā te homoni ADH (vasopressin) ka āwhina i te pupuri i te taurite i waenga i te nui o te wai e inuhia ana e tātou me te nui o te mimi e tukuna ana e tātou.

Whakaarohia, ina nui te werawera o te tangata hauora, ina iti rānei te wai e inumia ana e ia, ka piki ake ngā taumata ADH, ka kī atu ki ngā whatukuhu kia 'iti ake te mimi, kia penapena wai i roto i te tinana.' Waihoki, ina nui te wai i roto i te tinana, ka heke ngā taumata ADH, ka kī atu ki ngā whatukuhu kia 'kāore he aha, me hanga he mimi inaianei tonu.'

Heoi, ki te kore tō tinana e aro tika ki te ADH, ka nui rawa te mimi e whakaputaina ana e ō whatukuhu. Koinei te mea ka tupu i roto i te mate huka insipidus nephrogenic. Ka taea tēnei mate te tuku iho (he mea tuku iho) ka taea rānei te whanake i ngā wā katoa o tō oranga (he mea whiwhi) .

Te mate huka insipidus nephrogenic kua riro mai

Koinei te momo tino noa. Ka puta ina whakararuraru tetahi mea i te kaha o te tinana ki te aro atu ki te ADH. Hei tauira, ka puta pea i ētahi āhuatanga e pā ana ki ō whatukuhu. Ko ēnei āhuatanga ko:

• Amyloidosis – Koinei te wā e whakatakotoria ai he pūmua rerekē ki roto i ngā whekau tae atu ki ngā whatukuhu.
• Ētahi momo mate pukupuku
• Mate tākihi mau tonu
• ngā mate pukupuku, hei tauira, te pyelonephritis
• Mate tākihi polycystic – Koinei te wā e puta ai ngā whēkau kī tonu i te wai i roto i ngā tākihi.
• Whatukuhu hautai waenga

Tērā atu anō ngā take e pā ana ki tēnei:

• Ētahi rongoā: Ina koa ko te lithium (e whakamahia ana mō ētahi mate hinengaro) ina whakamahia mō te wā roa.
• Te iti o te pāhare pāporo i roto i te toto (hypokalemia)
• Te pikinga o ngā taumata konupūmā i roto i te toto (hypercalcemia)
• Te mate toto pūtau hāripiri
• Te mate a Sjögren – He mate tēnei e pā ana ki te pūnaha ārai mate.
• Te aukati i te ara mimi – hei tauira, he mea pērā i te kohatu mimi.

Mate huka insipidus nephrogenic tuku iho

Nā ngā whakarerekētanga ira o ngā ira AVPR2, AQP2 rānei tēnei i puta ai. Mā ēnei ira ka tohutohu te tinana ki te nui o te wai hei tāpiri ki te mimi. Ina he hapa ēnei ira, kāore e taea e ngā whatukuhu te aro atu ki te ADH. Ko ngā tohu o te mate huka insipidus nephrogenic, he mea whānau mai, ka puta i roto i ngā marama tuatahi o te oranga .

He aha ngā tohu o te Mate Huka Insipidus Nephrogenic?

Whakaarohia, e mōhio ana koe ki tētahi, me kī ko Sumana. He nui te matewai o Sumana i te rā katoa. Kei te mahi ia me tētahi pounamu wai nui e tata ana. Engari i roto i te haora i muri i te inu, ka matewai anō ia, ā, me haere pinepine ia ki te wharepaku, ā, he nui tana mimi. I ētahi wā ka ara ake ia i te rua, i te toru rānei ngā wā i te pō ki te mimi. I whakaaro ia, 'Nā te nui rawa o taku inu wai pea.' Engari koinei ngā tohu matua o te mate huka insipidus nephrogenic.

Tērā pea ka pāngia te tangata e te mate huka insipidus nephrogenic e ngā tohu pēnei i:

• Ngā tohu o te matewai: Te waha maroke, ngā ngutu pakarukaru, te ngenge nui, te pōuri, ā, i ētahi wā ka kikorangi ngā kanohi ina tū. Whakaarohia he rite ki te noho i raro i te rā mō te wā roa me te kore wai.
• Polydipsia: Te ahua nei kāore koe e whiwhi ana i te nui o te wai ahakoa te nui o te wai e inuhia ana e koe.
• Te mimi nui rawa (Polyuria): Mena ka mimi te pakeke neke atu i te 3 rita ia rā (i waenga i te 5-20 rita!), ā, ki te mimi te tamaiti neke atu i te 2 rita ia rā, he mea whakapae. He mārama rawa hoki te tae o te mimi, pērā i te wai.

Mena kei te pēpi tēnei mate, ka puta pea ēnei tohu nā te mea kāore ia e mārama ki te kōrero:

• Korere
• Te kore e tupu pai, te kore hoki e piki te taumaha – Te kore e piki te taumaha, te kore rānei e roa ake pērā i ētahi atu pēpi.
• Te kirika auau
• Te kore e okioki me te tangi tonu (Te riri) – te āhua nei kei te mamae te pēpi.
• Te ngaronga o te hiahia kai, te iti o te inu miraka
• Ngā mate pāwera - He tohu morearea tēnei.
• Ruaki
• Me whakawhiti pinepine i ngā nāpi mākū.

Me pēhea te tātaritanga o te Mate Huka Insipidus Nephrogenic?

Ki te pā mai ēnei tohu ki a koe, ko te mea tuatahi me mahi e koe ko te toro atu ki tētahi tākuta. Ka pātai atu ia ki a koe, ka tirotiro i a koe, ā, ki te tika, ka tono ia i ngā whakamātautau pēnei i:

• Ngā whakamātautau toto: Tirohia te taumata o ngā electrolytes, pērā i te konutai, i roto i te tinana, me te mahi a te tākihi.
• Ngā whakamātautau mimi:Tirohia te kukū o te mimi (te nui o tōna waimeha), me te nui o te wai kei roto i te mimi.
• Whakamātautau kore wai: Ko tēnei ko te kore inu wai mō ngā haora maha, kātahi ka aroturuki i tō taumaha, te putanga mimi, me te kukū toto me te mimi ia haora. He whakamātautau uaua tēnei, engari he mea tino nui mō te tautuhi mate. Koinei anake te huarahi hei whakatau tika mēnā kei te aro atu ngā whatukuhu ki te ADH. Ka mahia tēnei whakamātautau i raro i te tirotiro hauora i roto i te hōhipera.
• Te whakamātautau ki te homoni ADH: I ētahi wā, ka werohia te homoni ADH me te whakamātautau kore wai, kātahi ka tirohia mēnā ka rerekē te kukū o te mimi. I roto i te mate huka insipidus nephrogenic, ahakoa ka hoatu te ADH, kāore te kukū o te mimi e tino rerekē.
• Matawai MRI o tō repe pituitary (Whakaahua aukume): Ki te whakapae koe kei te pāngia koe e te mate huka insipidus matua, tirohia mēnā he hapa kei roto i te roro.
• Whakamātautau ira: Mena kei te pāngia tetahi o tō whānau e te mate huka insipidus, ki te whakapae rānei koe he momo tuku iho.

He rongoā katoa kei te wātea mō te mate huka insipidus nephrogenic?

Ki te pono, kāore anō kia kitea he rongoā katoa mō te mate huka insipidus nephrogenic.

Kaua e manukanuka. Ka taea te whakahaere. Tērā pea ka taea e tō tākuta te whakarerekē i ngā rongoā e tangohia ana e koe e puta ai te raruraru (pēnei i te lithium). Waihoki, mēnā he mate kē atu kei roto (pēnei i te mate tākihi, te kore taurite o te konupūmā/pāhare pākawa), mā te rongoā tika ka taea te whakakore, te whakahaere rānei i te mate huka insipidus nephrogenic.

Nā, me pēhea te whakahaere i tēnei?

Mēnā kāore e taea te whakaora (hei tauira, he whānautanga), ko te whāinga matua o te maimoatanga ko te ārai i te matewai me te pupuri i te kounga pai o te oranga. Kei roto i tēnei ko:

• Inu wai i ngā wā katoa: Koinei te mea nui rawa atu. Me inu wai koe i te roanga o te rā, i ngā wā katoa e matewai ana koe. Kia nui ake te inu wai, inā koa i ngā rā wera, i te wā e whakakorikori tinana ana, i te wā rānei e werawera ana koe. Puritia he pounamu wai i te taha o te pō.
• Ngā huringa o te kai:
• Kai iti te tote: Mā te kai nui rawa i te tote ka nui ake te matewai me te mimi.
• He kai iti-pūmua: I ētahi wā ka kīia atu kia whakawhāitihia te kai pūmua, nā te mea e hiahiatia ana hoki te wai hei tango i ngā para i puta i te wā nakunaku pūmua.
• Ngā rongoā e whakaiti ana i te putanga mimi:
• Ngā rongoā diuretic Thiazide:He mea whakamiharo, ina hoatu ēnei rongoā whakaheke toto ki te hunga e pangia ana e te mate huka insipidus nephrogenic, ka whakaitihia te nui o te mimi e puta ana. He ahua uaua, engari he whai hua.
• Amiloride: Ka taea te hoatu tahi me ngā thiazides, inā koa mō ngā NDI i puta mai i te lithium.
• Ngā Rongoā Ārai-Mumura Kore-Steroid (NSAID): Hei tauira, ko te indomethacin. Ka āwhina ēnei ki te whakanui ake i te tairongo o ngā whatukuhu ki te ADH.

He aha ngā kai me ngā inu me karo e te tangata whai mate pēnei?

Tērā pea ka kī atu tō tākuta kia whakawhāitihia te waipiro, ngā inu kawheine (pēnei i te kawhe, te tī, me ētahi inu ngāwari), ngā kai tote (pēnei i te pīkara, te mīti maroke, te hōtiti, me ngā parai), me ētahi atu kai pūmua nui pea, nā te mea ka nui ake te wai e ngaro i tō tinana, ka nui ake hoki te wai e inumia ana e koe.

He huarahi hei ārai i te mate huka insipidus nephrogenic?

Kāore he rautaki kua whakamātauhia hei ārai i tēnei. Kāore e taea te ārai i te momo whānautanga. Heoi, mō te momo kua riro mai:

• Mena kei te tango koe i ngā rongoā ka pāngia ai te NDI, pērā i te lithium, he mea nui kia kōrero koe ki tō tākuta mō tēnei mea, kia tirohia hoki te mahi a tō whatukuhu i ia wā.
• Mā te rongoā wawe me te tika mō ngā raruraru hauora taketake (te mate tākihi, te kore taurite o ngā electrolytes) ka taea te whakaiti i te mōrearea.

Mena kei a au tēnei āhuatanga, he aha taku e tumanako ai?

Koinei te rongo pai rawa atu. Mēnā he tika te maimoatanga me te oranga hauora , he iti ake ngā raruraru nui mō te hunga e pāngia ana e te mate huka insipidus nephrogenic, ā, ka taea e rātou te noho i te oranga noa . Ka taea e rātou te mahi me te pārekareka ki te oranga noa.

Heoi, ki te kore e whakahaerea tika, ka arahi pea tēnei ki ngā raruraru nui. Me titiro tātou ki ēnei āhuatanga:

• Te matewai: Koinei te raruraru tino noa, tino kino hoki. Ka taea e te matewai nui te arahi ki te ngaronga o te māramatanga, ngā haurangi, me te ngoikore o te whatukuhu.
• Te raruraru o te irahiko: He panoni tēnei i te nui o ngā irahiko (pērā i te konutai me te pāhare pāporo) i roto i te tinana. Ka pā pea tēnei ki te tere o te manawa me te mahi a ngā io.
• Ngā mate urutā: Ngā mate pēnei i te mate urutā o te ara mimi (UTI) me ngā mate tākihi.
• Te whakaroa i te whanaketanga, te pakaru o te roro me te hauātanga hinengaro o ngā pēpi. He tino morearea tēnei mō ngā tamariki nohinohi. Nō reira, ki te pāngia te pēpi e ēnei tohu, me tīmata tonu te maimoatanga.
• Te ngoikore o te whatukuhu: Ka pā mai pea i roto i te wā roa mena kāore e tika ana te whakahaere.
• Te Hydronephrosis: Nā te mea e kī tonu ana te pūkahukahu, ka hoki whakamuri te mimi, ā, ka pupuhi ngā whatukuhu.

Āhea koe me rapu tohutohu hauora?

Mena he ruarua, he āwangawanga rānei ōu mō te nui o te mimi e mimihia ana e koe, inā koa he nui tō mimi me te nui rawa o te mimi, me toro atu koe ki te tākuta.

Ka rerekē te nui o te mimi e mimia ana e te pakeke i ia rā, i ia tangata, i ia tangata, inā koa i runga i te nui o te wai e inuhia ana e rātou. Engari, ki te neke atu i te 2-3 rita tō mimi i ia rā (e kī ana ētahi whakamāramatanga neke atu i te 3 rita), ki te mimi pinepine rānei koe (neke atu i te whitu, i te waru rānei ngā wā i te rā) , he tohu pea tēnei mō tētahi raruraru.

I mua i te haerenga ki te tākuta, he mea tino whai hua te tuhi i tētahi pukapuka rātaka mō te nui o te wai e inuhia ana e koe me te nui o te mimi e whakaputaina ana e koe (me ine mēnā ka taea). Mā tēnei ka māmā ake te mārama o te tākuta ki tō āhua.

Nā, he aha ngā mea hei maumahara mā tātou i tēnei pūrākau? (Karere hei tango ki te kāinga)

He āhuatanga onge te Mate Huka Insipidus Nephrogenic, e kore ai ō whatukuhu e aro tika ki te homoni ADH i roto i tō tinana, ka nui rawa te mimi e whakaputaina ana e koe. Ka taea e tēnei te arahi ki te matewai tere.

• Ko ngā tohu matua ko te matewai nui me te mimi wai nui .
• Kaua tēnei e whakapoauautia ki te mate huka; i tēnei wā, he noa te taumata huka toto.
• Ka kitea pea tēnei āhuatanga i te whānautanga mai, ka whanake rānei i muri mai i te ao.
• Ahakoa kāore he rongoā katoa, mā te maimoatanga hauora tika me ngā huringa momo noho (ina koa te inu wai nui me te whakahaere i tāu kai), ka taea e koe te noho ora, hauora hoki.
• Ki te whakapae koe kei a koe, kei tāu tamaiti rānei tētahi o ēnei tohu, rapua tonutia he tohutohu hauora. Kaua e mataku, engari ko te mea nui ko te mōhio me te mahi i ngā mahi e tika ana. Kāore koe i te mokemoke, ā, ka taea e ngā tākuta te āwhina i a koe.

Mate huka insipidus nephrogenic, mate tākihi, mimi nui, matewai nui, ADH, vasopressin, matewai