ꯅꯍꯥꯛꯀꯤꯗꯃꯛꯇꯥ ꯆꯨꯅꯕꯥ ꯑꯃꯁꯨꯡ ꯅꯍꯥꯀꯄꯨ ꯂꯧꯁꯤꯅꯕꯥ ꯉꯝꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯥ ꯊꯤꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯃꯇꯃꯗꯥ ꯈꯔꯥ ꯑꯋꯥꯕꯥ ꯑꯣꯏꯕꯥ ꯌꯥꯏ꯫ ꯑꯩꯈꯣꯌ ꯄꯨꯝꯅꯃꯛ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ, ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯗꯔꯀꯥꯔ ꯑꯣꯏꯕꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯄꯁꯟꯗꯁꯤꯡ ꯂꯩꯔꯤ꯫ ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ hATTR Amyloidosis ꯒꯨꯝꯕꯥ ꯌꯥꯝꯅꯥ ꯊꯨꯅꯥ ꯊꯣꯀꯄꯥ ꯀꯟꯗꯤꯁꯟ ꯑꯃꯥ ꯂꯩꯔꯕꯗꯤ, ꯅꯍꯥꯛꯅꯥ ꯃꯁꯤ ꯍꯦꯟꯅꯥ ꯂꯨꯝꯅꯥ ꯂꯧꯕꯥ ꯌꯥꯏ꯫ ꯑꯁꯤꯒꯨꯝꯕꯥ ꯀꯟꯗꯤꯁꯟ ꯑꯁꯤ ꯂꯥꯏꯌꯦꯡꯕꯥ ꯃꯇꯃꯗꯥ, ꯂꯥꯌꯅꯥ ꯑꯁꯤꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯑꯐꯕꯥ ꯂꯧꯁꯤꯡ ꯂꯩꯕꯥ ꯑꯃꯁꯨꯡ ꯅꯍꯥꯛꯅꯥ ꯃꯊꯧ ꯇꯥꯔꯤꯕꯥ ꯀꯦꯌꯔꯒꯤ ꯊꯥꯛ ꯑꯗꯨ ꯄꯤꯒꯗꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯥ ꯊꯤꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫ ꯇꯁꯦꯡꯕꯗꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯂꯥꯌꯦꯡ ꯐꯪꯅꯕꯒꯤꯗꯃꯛ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯂꯃꯁꯤꯡꯗꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯀꯌꯥ ꯑꯃꯥ ꯊꯤꯕꯥ ꯃꯊꯧ ꯇꯥꯏ꯫
ꯀꯔꯤ ꯃꯈꯂꯒꯤ ꯗꯣꯛꯇꯔꯁꯤꯡꯅꯥ hATTR ꯂꯥꯌꯦꯡꯂꯤꯕꯅꯣ?
ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯍꯥꯌꯔꯕꯗꯥ, hATTR ꯑꯦꯃꯤꯂꯣꯏꯗꯣꯁꯤꯁ ꯑꯁꯤ ꯃꯇꯝ ꯑꯃꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯍꯀꯆꯥꯡꯒꯤ ꯃꯁꯤꯡ ꯌꯥꯝꯂꯕꯥ ꯑꯣꯔꯒꯥꯅꯁꯤꯡꯗꯥ ꯁꯣꯀꯍꯅꯕꯥ ꯌꯥꯕꯥ ꯌꯥꯝꯅꯥ ꯊꯨꯅꯥ ꯊꯣꯀꯄꯥ ꯂꯥꯌꯅꯥ ꯑꯃꯅꯤ꯫ ꯃꯁꯤꯅꯥ ꯇꯥꯀꯄꯗꯤ ꯅꯍꯥꯛꯅꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯑꯃꯈꯛꯇꯗꯒꯤ ꯂꯥꯏꯌꯦꯡꯕꯥ ꯉꯃꯂꯣꯏ꯫ ꯃꯜꯇꯤꯗꯤꯁꯤꯞꯂꯤꯅꯔꯤ ꯇꯤꯝ ꯑꯃꯒꯤ ꯃꯇꯦꯡ ꯃꯊꯧ ꯇꯥꯒꯅꯤ꯫
ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯀꯤ ꯊꯝꯃꯣꯌꯗꯥ ꯂꯥꯌꯅꯥ ꯑꯁꯤꯅꯥ ꯁꯣꯀꯍꯜꯂꯕꯗꯤ ꯅꯍꯥꯛꯅꯥ ꯀꯥꯔꯗꯤꯑꯣꯂꯣꯖꯤꯁ꯭ꯠ ꯑꯃꯒꯥ ꯇꯥꯟꯅꯒꯗꯕꯅꯤ꯫ ꯑꯃꯔꯣꯃꯗꯥ, ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯅ꯭ꯌꯨꯔꯣꯂꯣꯖꯤꯀꯦꯜ ꯄ꯭ꯔꯣꯕ꯭ꯂꯦꯝ ꯑꯃꯥ ꯂꯩꯔꯕꯗꯤ, ꯍꯥꯌꯕꯗꯤ ꯅꯍꯥꯛꯀꯤ ꯈꯣꯡꯗꯥ ꯁꯣꯀꯄꯥ ꯅꯠꯠꯔꯒꯥ ꯁꯣꯟꯊꯕꯥ ꯑꯁꯤꯅꯆꯤꯡꯕꯥ ꯂꯩꯔꯕꯗꯤ ꯅꯍꯥꯛꯅꯥ ꯅ꯭ꯌꯨꯔꯣꯂꯣꯖꯤꯁ꯭ꯠ ꯑꯃꯒꯥ ꯇꯥꯟꯅꯒꯗꯕꯅꯤ꯫ ꯑꯗꯨꯅꯥ, ꯅꯍꯥꯛꯅꯥ ꯊꯦꯡꯅꯔꯤꯕꯥ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ, ꯁꯣꯀꯍꯜꯂꯕꯥ ꯑꯣꯔꯒꯥꯅꯁꯤꯡ, ꯑꯃꯁꯨꯡ ꯂꯥꯌꯅꯥ ꯑꯁꯤꯅꯥ ꯊꯣꯀꯍꯅꯕꯥ ꯑꯃꯥꯡ-ꯑꯇꯥꯒꯤ ꯆꯥꯡ ꯑꯁꯤꯅꯥ ꯅꯍꯥꯛꯅꯥ ꯀꯔꯤ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯇꯁꯤꯡ ꯌꯦꯡꯒꯗꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯂꯦꯄꯀꯅꯤ꯫
ꯃꯈꯥꯗꯥ ꯄꯤꯔꯤꯕꯥ ꯇꯦꯕꯜ ꯑꯁꯤꯗꯥ ꯑꯩꯈꯣꯌꯅꯥ hATTR ꯂꯥꯌꯅꯥꯗꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯍꯦꯟꯅꯥ ꯃꯊꯧ ꯇꯥꯕꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯇꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯃꯈꯣꯌꯅꯥ ꯀꯔꯤ ꯃꯈꯂꯒꯤ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ ꯂꯥꯌꯦꯡꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯌꯦꯡꯒꯅꯤ꯫
| ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯃꯦꯗꯤꯀꯦꯂꯒꯤ ꯂꯃꯗꯥ꯫ | ꯃꯈꯣꯌꯅꯥ ꯂꯥꯏꯌꯦꯡꯂꯤꯕꯥ ꯀꯃꯟ ꯑꯣꯏꯕꯥ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ/ ꯀꯟꯗꯤꯁꯅꯁꯤꯡ꯫ |
|---|---|
| ꯀꯥꯔꯗꯤꯑꯣꯂꯣꯖꯤꯁ꯭ꯠ꯫ | ꯍꯥꯔꯇꯀꯤ ꯐꯉ꯭ꯀꯁꯟ ꯁꯣꯟꯊꯕꯥ (Cardiomyopathy), ꯍꯥꯔꯇꯀꯤ ꯔꯤꯗꯝ ꯑꯥꯏꯔꯦꯒꯨꯂꯦꯁꯟ, ꯁ꯭ꯕꯔ ꯍꯣꯅꯕꯥ ꯋꯥꯕꯥ꯫ |
| ꯅ꯭ꯌꯨꯔꯣꯂꯣꯖꯤꯁ꯭ꯠ ꯑꯣꯏꯅꯥ ꯊꯕꯛ ꯇꯧꯕꯥ꯫ | ꯃꯁꯥ ꯃꯊꯟꯇꯥ ꯁꯣꯟꯊꯕꯥ, ꯁꯣꯟꯊꯕꯥ, ꯑꯅꯥꯕꯥ, ꯑꯃꯁꯨꯡ ꯂꯦꯡ-ꯑꯣꯠꯄꯗꯥ ꯋꯥꯈꯜ ꯃꯥꯡꯈꯤꯕꯥ (Peripheral Neuropathy)꯫ |
| ꯒꯦꯁ꯭ꯠꯔꯣꯑꯦꯟꯇꯦꯔꯣꯂꯣꯖꯤꯁ꯭ꯠ꯫ | ꯈꯣꯡ ꯍꯥꯝꯕꯥ, ꯗꯥꯏꯔꯤꯌꯥ, ꯈꯣꯡ ꯍꯥꯝꯕꯥ, ꯑꯔꯨꯝꯕꯥ ꯍꯟꯊꯕꯥ, ꯋꯥꯈꯜ ꯆꯔꯥꯡꯅꯕꯥ꯫ |
| ꯅꯦꯐ꯭ꯔꯣꯂꯣꯖꯤꯁ꯭ꯠ ꯑꯣꯏꯕꯥ꯫ | ꯀꯤꯗꯅꯤꯁꯤꯡꯗꯥ ꯁꯣꯀꯍꯜꯂꯕꯥ ꯃꯇꯃꯗꯥ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯌꯨꯔꯤꯅꯗꯥ ꯄ꯭ꯔꯣꯇꯤꯟ)꯫ |
| ꯑꯣꯐꯊꯥꯂꯃꯣꯂꯣꯖꯤꯁ꯭ꯠ꯫ | ꯃꯤꯠꯇꯥ ꯁꯣꯀꯍꯜꯂꯕꯥ ꯃꯇꯃꯗꯥ (ꯈꯨꯗꯝ ꯑꯣꯏꯅꯥ, ꯃꯤꯠꯀꯤ ꯄ꯭ꯔꯦꯁꯔ ꯍꯦꯅꯒꯠꯂꯀꯄꯥ, ꯃꯤꯠ ꯎꯗꯕꯥ)꯫ |
| ꯖꯦꯅꯦꯇꯤꯛ ꯀꯥꯎꯟꯁꯦꯂꯔ ꯑꯣꯏꯅꯥ ꯊꯕꯛ ꯇꯧꯕꯥ꯫ | ꯃꯁꯤ ꯍꯦꯔꯤꯇꯦꯖ ꯑꯣꯏꯕꯥ ꯂꯥꯌꯅꯥ ꯑꯃꯥ ꯑꯣꯏꯕꯅꯥ ꯏꯃꯨꯡꯁꯤꯡꯗꯥ ꯔꯤꯁ꯭ꯛ ꯑꯃꯁꯨꯡ ꯖꯦꯅꯦꯇꯤꯛ ꯇꯦꯁ꯭ꯇꯤꯡꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯄꯥꯎꯇꯥꯛ ꯄꯤꯒꯗꯕꯅꯤ꯫ |
ꯅꯍꯥꯛꯀꯤ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ ꯑꯁꯤ ꯂꯥꯌꯅꯥ ꯑꯁꯤ ꯊꯣꯀꯍꯜꯂꯤꯕꯥ ꯇ꯭ꯔꯥꯟꯁꯊꯥꯏꯔꯦꯇꯤꯟ (TTR) ꯖꯤꯅꯒꯤ ꯑꯀꯛꯅꯕꯥ ꯃ꯭ꯌꯨꯇꯦꯁꯟ ꯑꯗꯨꯒꯤ ꯃꯈꯥ ꯄꯣꯅꯕꯥ ꯌꯥꯏ꯫ ꯃꯁꯤꯅꯥ ꯅꯍꯥꯛꯅꯥ ꯀꯔꯤ ꯃꯈꯂꯒꯤ ꯗꯣꯛꯇꯔꯁꯤꯡ ꯃꯊꯧ ꯇꯥꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯂꯦꯄꯀꯅꯤ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯂꯥꯌꯅꯥ ꯑꯁꯤꯅꯥ ꯅꯥꯔꯀꯄꯥ ꯃꯇꯃꯗꯥ ꯃꯇꯃꯒꯤ ꯃꯇꯨꯡꯏꯟꯅꯥ ꯑꯅꯧꯕꯥ ꯂꯥꯏꯑꯣꯡꯁꯤꯡ ꯂꯥꯀꯄꯥ ꯇꯥꯔꯕꯗꯤ ꯅꯍꯥꯛꯅꯥ ꯑꯇꯩ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯇꯁꯤꯡꯗꯁꯨ ꯌꯦꯡꯁꯤꯅꯕꯥ ꯃꯊꯧ ꯇꯥꯕꯥ ꯌꯥꯏ꯫
ꯁ꯭ꯔꯤꯂꯉ꯭ꯀꯥꯗꯥ hATTR ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯑꯃꯥ ꯀꯔꯝꯅꯥ ꯊꯤꯒꯅꯤ?
ꯑꯁꯤꯒꯨꯝꯕꯥ ꯌꯥꯝꯅꯥ ꯇꯣꯏꯅꯥ ꯊꯣꯀꯄꯥ ꯂꯥꯌꯅꯥ ꯑꯃꯥ ꯂꯥꯏꯌꯦꯡꯕꯥ ꯃꯇꯃꯗꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯀꯦꯌꯔ ꯂꯧꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫ ꯁ꯭ꯔꯤꯂꯉ꯭ꯀꯥꯗꯥ ꯃꯁꯤ ꯇꯧꯅꯕꯒꯤ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯄꯥꯝꯕꯩꯗꯤ ꯃꯐꯝ ꯑꯃꯗꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯀꯌꯥꯅꯥ ꯊꯕꯛ ꯇꯧꯔꯤꯕꯥ ꯑꯆꯧꯕꯥ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯜ ꯑꯃꯗꯥ ꯆꯠꯄꯅꯤ꯫
ꯃꯍꯧꯁꯥꯅꯥ ꯇꯤꯆꯤꯡ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯂꯁꯤꯡ ꯑꯃꯁꯨꯡ ꯁ꯭ꯔꯤꯂꯉ꯭ꯀꯥꯒꯤ ꯅꯦꯁ꯭ꯅꯦꯜ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯂꯒꯨꯝꯕꯥ ꯑꯆꯧꯕꯥ ꯁꯔꯀꯥꯔꯒꯤ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯂꯁꯤꯡꯗꯥ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯍꯤꯔꯃꯁꯤꯡꯒꯤ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯇꯁꯤꯡꯅꯥ ꯑꯅꯥꯕꯁꯤꯡ ꯂꯥꯌꯦꯡꯅꯕꯥ ꯄꯨꯟꯅꯥ ꯂꯥꯀꯃꯤꯟꯅꯩ꯫ ꯑꯆꯧꯕꯥ ꯄ꯭ꯔꯥꯏꯕꯦꯠ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯜ ꯈꯔꯗꯁꯨ ꯃꯁꯤꯒꯤ ꯈꯨꯗꯣꯡꯆꯥꯕꯥ ꯑꯁꯤ ꯂꯩꯕꯥ ꯌꯥꯏ꯫
ꯈꯣꯡꯆꯠ ꯑꯁꯤꯒꯤ ꯑꯍꯥꯅꯕꯥ ꯈꯣꯡꯊꯥꯡ ꯑꯁꯤ ꯅꯍꯥꯛꯀꯤ ꯐꯦꯃꯤꯂꯤ ꯗꯣꯛꯇꯔ (GP)ꯒꯥ ꯎꯅꯕꯅꯤ꯫ ꯃꯍꯥꯛꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯂꯥꯏꯑꯣꯡꯁꯤꯡꯒꯤ ꯃꯇꯨꯡꯏꯟꯅꯥ, ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯆꯨꯅꯕꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯅꯠꯠꯔꯒꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯇꯁꯤꯡꯒꯤ ꯀꯥꯡꯕꯨ ꯑꯃꯥ ꯂꯩꯕꯥ ꯍꯣꯁ꯭ꯄꯤꯇꯥꯜ ꯑꯃꯗꯥ ꯔꯤꯐꯔ ꯇꯧꯕꯥ ꯌꯥꯏ꯫
ꯑꯁꯤꯒꯨꯝꯕꯥ ꯁꯦꯟꯇꯔ ꯑꯃꯗꯥ ꯂꯥꯌꯦꯡꯕꯒꯤ ꯀꯥꯟꯅꯕꯗꯤ ꯅꯍꯥꯛꯀꯤ ꯄꯨꯝꯅꯃꯛ...ꯃꯐꯝ ꯑꯃꯗꯥ ꯃꯦꯗꯤꯀꯦꯜ ꯔꯦꯀꯣꯔꯗ ꯂꯩꯕꯥ ꯍꯥꯌꯕꯁꯤꯅꯥ ꯗꯣꯛꯇꯔꯁꯤꯡꯅꯥ ꯑꯃꯒꯥ ꯑꯃꯒꯥ ꯅꯍꯥꯛꯀꯤ ꯀꯟꯗꯤꯁꯟ ꯑꯗꯨ ꯐꯖꯅꯥ ꯈꯟꯅ-ꯅꯩꯅꯕꯥ ꯌꯥꯏ ꯑꯃꯁꯨꯡ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯂꯥꯏꯌꯦꯡꯕꯒꯤ ꯊꯧꯔꯥꯡ ꯁꯦꯝꯕꯥ ꯌꯥꯏ꯫ ꯅꯍꯥꯛꯅꯥ ꯑꯅꯧꯕꯥ ꯂꯥꯏꯌꯦꯡꯁꯤꯡ ꯅꯠꯠꯔꯒꯥ ꯀ꯭ꯂꯤꯅꯤꯀꯦꯜ ꯇ꯭ꯔꯥꯏꯑꯦꯂꯁꯤꯡꯒꯤ ꯃꯇꯥꯡꯗꯁꯨ ꯈꯪꯕꯥ ꯌꯥꯏ꯫
ꯑꯩꯒꯤ ꯏꯃꯨꯡꯒꯤ ꯗꯣꯛꯇꯔ ꯑꯗꯨ ꯍꯧꯖꯤꯀꯁꯨ ꯃꯊꯧ ꯇꯥꯕꯔꯥ?
ꯍꯣꯌ, ꯃꯄꯨꯡ ꯐꯥꯅꯥ꯫ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ hATTR ꯂꯩꯔꯕꯁꯨ, ꯅꯍꯥꯛꯀꯤ ꯄ꯭ꯔꯥꯏꯃꯥꯔꯤ ꯀꯦꯌꯔ ꯗꯣꯛꯇꯔ ꯑꯗꯨ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫ ꯃꯍꯥꯛ ꯅꯍꯥꯛꯀꯤ ꯍꯀꯁꯦꯂꯒꯤ ꯁꯦꯟꯇꯔꯅꯤ꯫ ꯑꯗꯣꯃꯒꯤ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯇꯁꯤꯡꯒꯤ ꯀꯥꯡꯕꯨ ꯑꯃꯁꯨꯡ ꯑꯗꯣꯃꯒꯤ ꯏꯃꯨꯡꯒꯤ ꯗꯣꯛꯇꯔꯒꯤ ꯃꯔꯛꯇꯥ ꯑꯐꯕꯥ ꯄꯥꯎ ꯐꯥꯑꯣꯅꯕꯥ ꯑꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ . ꯅꯍꯥꯛꯅꯥ ꯎꯈꯤꯕꯥ, ꯂꯥꯌꯦꯡꯈꯤꯕꯥ, ꯇꯦꯁ꯭ꯠ ꯇꯧꯈꯤꯕꯥ ꯑꯁꯤꯅꯆꯤꯡꯕꯥ ꯄꯨꯝꯅꯃꯛꯀꯤ ꯃꯇꯥꯡꯗꯥ ꯅꯍꯥꯛꯀꯤ ꯐꯦꯃꯤꯂꯤ ꯗꯣꯛꯇꯔꯗꯥ ꯈꯪꯍꯅꯕꯥ ꯀꯥꯎꯒꯅꯨ, ꯃꯁꯤꯗꯁꯨ ꯅꯠꯇꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯠ ꯔꯤꯄꯣꯔꯇꯁꯤꯡꯒꯤ ꯀꯣꯄꯤꯁꯤꯡ ꯑꯗꯨ ꯅꯍꯥꯛꯀꯤ ꯐꯦꯃꯤꯂꯤ ꯗꯣꯛꯇꯔꯗꯥ ꯄꯤꯌꯨ꯫
ꯑꯩꯒꯤ ꯂꯥꯏꯌꯦꯡ ꯑꯁꯤ ꯃꯇꯧ ꯀꯔꯝꯅꯥ ꯃꯁꯤꯡ ꯌꯥꯝꯂꯕꯥ ꯗꯣꯛꯇꯔꯁꯤꯡꯒꯥ ꯀꯣꯑꯣꯔꯗꯤꯅꯦꯠ ꯇꯧꯒꯅꯤ?
ꯃꯁꯤ ꯈꯔꯥ ꯁꯤꯡꯅꯕꯥ ꯑꯃꯥ ꯑꯣꯏꯔꯕꯁꯨ, ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯃꯃꯥꯡꯗꯥ ꯊꯧꯔꯥꯡ ꯇꯧꯔꯕꯗꯤ ꯃꯁꯤ ꯌꯥꯝꯅꯥ ꯂꯥꯏ꯫
- ꯅꯍꯥꯛꯀꯤ ꯏꯁꯥꯒꯤ ꯐꯥꯏꯜ ꯑꯃꯥ ꯊꯝꯃꯨ: ꯅꯍꯥꯛꯀꯤ ꯇꯦꯁ꯭ꯠ ꯔꯤꯄꯣꯔꯠ, ꯄ꯭ꯔꯦꯁ꯭ꯛꯔꯤꯄꯁꯟ ꯑꯃꯁꯨꯡ ꯏꯅꯁ꯭ꯠꯔꯛꯁꯟ ꯄꯨꯝꯅꯃꯛ ꯐꯥꯏꯜ ꯑꯃꯗꯥ ꯊꯝꯃꯨ꯫ ꯀ꯭ꯂꯤꯅꯤꯛ ꯂꯥꯏꯔꯤꯛ ꯑꯃꯥ ꯊꯝꯕꯥ꯫
- ꯄꯨꯝꯅꯃꯛ ꯈꯪꯖꯤꯅꯕꯤꯌꯨ: ꯅꯍꯥꯛꯅꯥ ꯎꯔꯤꯕꯥ ꯗꯣꯛꯇꯔ ꯈꯨꯗꯤꯡꯃꯛꯇꯥ ꯅꯍꯥꯛꯅꯥ ꯂꯥꯀꯄꯥ ꯑꯅꯧꯕꯥ ꯂꯥꯏꯑꯣꯡ ꯑꯃꯍꯦꯛꯇꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯈꯪꯍꯅꯕꯤꯌꯨ, ꯅꯠꯠꯔꯒꯥ ꯀꯔꯤꯒꯨꯝꯕꯥ ꯑꯔꯤꯕꯥ ꯂꯥꯏꯑꯣꯡ ꯑꯃꯥ ꯍꯦꯟꯅꯥ ꯐꯠꯆꯤꯜꯂꯛꯂꯕꯗꯤ꯫
- ꯋꯥꯍꯪꯁꯤꯡ ꯍꯪꯕꯤꯌꯨ: ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯈꯪꯗꯕꯥ ꯋꯥꯐꯝ ꯑꯃꯥ ꯂꯩꯔꯕꯗꯤ, ꯅꯍꯥꯛꯀꯤ ꯗꯣꯛꯇꯔꯗꯥ ꯑꯃꯨꯛ ꯍꯟꯅꯥ ꯍꯪꯕꯗꯥ ꯂꯥꯡꯇꯛꯅꯒꯅꯨ꯫ ꯅꯍꯥꯛꯀꯤ ꯂꯥꯌꯅꯥ ꯑꯃꯁꯨꯡ ꯂꯥꯏꯌꯦꯡꯒꯤ ꯃꯔꯃꯗꯥ ꯑꯐꯕꯥ ꯂꯧꯁꯤꯡ ꯂꯩꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫
ꯑꯩꯒꯤꯗꯃꯛꯇꯗꯤ ꯃꯇꯧ ꯀꯔꯝꯅꯥ ꯑꯆꯨꯝꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯥ ꯈꯅꯒꯗꯒꯦ?
ꯅꯍꯥꯀꯄꯨ ꯂꯥꯏꯌꯦꯡꯂꯤꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯗꯨꯒꯥ ꯑꯐꯕꯥ ꯃꯔꯤ ꯑꯃꯥ ꯊꯝꯕꯥ ꯃꯊꯧ ꯇꯥꯏ, ꯃꯔꯃꯗꯤ ꯃꯁꯤ ꯃꯇꯝ ꯁꯥꯡꯅꯥ ꯆꯠꯀꯗꯕꯥ ꯈꯣꯉꯆꯠ ꯑꯃꯅꯤ꯫
ꯅꯍꯥꯛꯀꯤ ꯋꯥ ꯇꯥꯕꯥ, ꯅꯍꯥꯀꯄꯨ ꯏꯀꯥꯏ ꯈꯨꯝꯅꯅꯥ ꯌꯦꯡꯁꯤꯅꯕꯥ ꯑꯃꯁꯨꯡ ꯅꯍꯥꯛꯅꯥ ꯍꯥꯌꯔꯤꯕꯥ ꯑꯗꯨ ꯈꯪꯂꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯥ ꯈꯅꯕꯁꯤ ꯅꯍꯥꯛꯀꯤ ꯍꯀꯅꯤ꯫
ꯅꯍꯥꯛꯅꯥ ꯅꯍꯥꯛꯀꯤ ꯏꯁꯥꯒꯤ ꯖꯦꯟꯗꯔꯒꯤ ꯗꯣꯛꯇꯔ ꯑꯃꯥ ꯍꯦꯟꯅꯥ ꯄꯥꯝꯂꯕꯁꯨ ꯌꯥꯏ꯫ ꯅꯠꯔꯒꯥ, ꯅꯍꯥꯛꯅꯥ ꯂꯧꯁꯤꯅꯕꯥ ꯉꯝꯕꯥ ꯃꯑꯣꯡꯗꯥ ꯋꯥꯐꯃꯁꯤꯡ ꯐꯣꯡꯗꯣꯀꯄꯥ ꯃꯤꯑꯣꯏ ꯑꯃꯥ ꯅꯍꯥꯛꯅꯥ ꯍꯦꯟꯅꯥ ꯄꯥꯝꯂꯕꯁꯨ ꯌꯥꯏ꯫ ꯑꯁꯤꯒꯨꯝꯕꯥ ꯍꯦꯔꯤꯇꯦꯖ ꯀꯟꯗꯤꯁꯟ ꯑꯃꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯊꯦꯡꯅꯔꯀꯄꯥ ꯃꯇꯃꯗꯥ, ꯃꯁꯤꯅꯥ ꯑꯇꯣꯞꯄꯥ ꯏꯃꯨꯡꯒꯤ ꯃꯤꯑꯣꯏꯁꯤꯡꯗꯥ ꯀꯔꯝꯅꯥ ꯁꯣꯀꯍꯅꯕꯒꯦ ꯑꯃꯁꯨꯡ ꯃꯈꯣꯌꯅꯥ ꯀꯔꯤ ꯇꯦꯁ꯭ꯇꯁꯤꯡ ꯃꯊꯧ ꯇꯥꯕꯒꯦ ꯍꯥꯌꯕꯗꯨ ꯅꯍꯥꯀꯄꯨ ꯂꯃꯖꯤꯡꯕꯤꯕꯥ ꯉꯝꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯒꯥ ꯇꯥꯟꯅꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫
ꯀꯔꯤꯒꯨꯝꯕꯥ ꯅꯍꯥꯛꯅꯥ ꯎꯔꯤꯕꯥ ꯑꯍꯥꯅꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯗꯨꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯅꯨꯡꯉꯥꯏꯇꯕꯥ ꯐꯥꯑꯣꯗ꯭ꯔꯕꯗꯤ, ꯃꯗꯨꯒꯤ ꯃꯇꯥꯡꯗꯥ ꯋꯥꯈꯜ ꯋꯥꯕꯥ ꯂꯩꯔꯣꯏꯗꯕꯅꯤ꯫ ꯑꯗꯣꯃꯒꯤꯗꯃꯛꯇꯥ ꯑꯐꯕꯥ ꯐꯤꯠ ꯑꯣꯏꯕꯥ ꯑꯃꯁꯨꯡ ꯑꯗꯣꯃꯒꯤ ꯗꯔꯀꯥꯔ ꯑꯣꯏꯕꯁꯤꯡ ꯈꯉꯕꯥ ꯉꯝꯕꯥ ꯑꯇꯣꯞꯄꯥ ꯑꯐꯕꯥ ꯗꯣꯛꯇꯔꯁꯤꯡꯁꯨ ꯂꯩꯔꯤ꯫ ꯔꯤꯁꯔꯆ ꯈꯔꯥ ꯇꯧꯕꯤꯌꯨ ꯑꯃꯁꯨꯡ ꯅꯍꯥꯛꯀꯤꯗꯃꯛꯇꯥ ꯈ꯭ꯕꯥꯏꯗꯒꯤ ꯐꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯥ ꯊꯤꯕꯤꯌꯨ꯫
ꯇꯦꯛ-ꯍꯣꯝ ꯃꯦꯁꯦꯖ ꯇꯧꯕꯥ꯫
- hATTR ꯑꯦꯃꯤꯂꯣꯏꯗꯣꯁꯤꯁ ꯑꯁꯤ ꯍꯀꯆꯥꯡꯒꯤ ꯃꯁꯤꯡ ꯌꯥꯝꯂꯕꯥ ꯑꯣꯔꯒꯥꯅꯁꯤꯡꯗꯥ ꯁꯣꯀꯍꯜꯂꯤꯕꯥ ꯂꯥꯌꯅꯥ ꯑꯃꯅꯤ, ꯃꯔꯝ ꯑꯗꯨꯅꯥ ꯑꯗꯣꯝꯅꯥ ꯇꯣꯉꯥꯟ ꯇꯣꯉꯥꯅꯕꯥ ꯂꯃꯁꯤꯡꯗꯥ ꯑꯈꯉ-ꯑꯍꯩꯁꯤꯡ ꯂꯩꯕꯥ ꯗꯣꯛꯇꯔꯁꯤꯡꯒꯤ ꯀꯥꯡꯕꯨ ꯑꯃꯒꯤ ꯃꯇꯦꯡ ꯃꯊꯧ ꯇꯥꯒꯅꯤ꯫
- ꯅꯍꯥꯛꯀꯤ ꯈꯣꯉꯆꯠꯀꯤ ꯑꯍꯥꯅꯕꯥ ꯈꯣꯡꯊꯥꯡꯗꯤ ꯅꯍꯥꯛꯀꯤ ꯐꯦꯃꯤꯂꯤ ꯗꯣꯛꯇꯔ (GP)ꯒꯥ ꯇꯥꯟꯅꯕꯅꯤ꯫ ꯃꯍꯥꯛꯅꯥ ꯅꯍꯥꯀꯄꯨ ꯃꯔꯤ ꯂꯩꯅꯕꯥ ꯁ꯭ꯄꯦꯁꯤꯑꯦꯂꯤꯁ꯭ꯇꯁꯤꯡꯗꯥ ꯔꯤꯐꯔ ꯇꯧꯒꯅꯤ꯫
- ꯅꯍꯥꯀꯄꯨ ꯂꯥꯏꯌꯦꯡꯂꯤꯕꯥ ꯗꯣꯛꯇꯔ ꯄꯨꯝꯅꯃꯛꯀꯤ ꯃꯔꯛꯇꯥ ꯑꯐꯕꯥ ꯄꯥꯎ ꯐꯥꯎꯗꯣꯛ-ꯐꯥꯎꯖꯤꯟ ꯊꯝꯕꯥ ꯍꯥꯌꯕꯁꯤ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫ ꯅꯍꯥꯛꯀꯤ ꯃꯦꯗꯤꯀꯦꯜ ꯔꯦꯀꯣꯔꯗ ꯄꯨꯝꯅꯃꯛ ꯃꯑꯣꯡ ꯆꯨꯝꯅꯥ ꯊꯝꯃꯨ꯫
- ꯅꯍꯥꯛꯀꯤ ꯋꯥ ꯇꯥꯕꯥ, ꯅꯍꯥꯀꯄꯨ ꯏꯀꯥꯏ ꯈꯨꯝꯅꯕꯥ ꯑꯃꯁꯨꯡ ꯅꯍꯥꯀꯄꯨ ꯋꯥꯐꯃꯁꯤꯡ ꯌꯥꯝꯅꯥ ꯂꯥꯏꯅꯥ ꯈꯪꯍꯅꯕꯥ ꯉꯝꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯥ ꯊꯤꯅꯕꯥ ꯃꯇꯝ ꯂꯧꯕꯤꯌꯨ꯫ ꯅꯍꯥꯛꯅꯥ ꯅꯨꯡꯉꯥꯏꯕꯥ ꯑꯃꯁꯨꯡ ꯊꯥꯖꯕꯥ ꯌꯥꯕꯥ ꯗꯣꯛꯇꯔ ꯑꯃꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯂꯥꯏꯌꯦꯡ ꯂꯧꯕꯥ ꯍꯥꯌꯕꯁꯤꯁꯨ ꯅꯍꯥꯛꯀꯤ ꯋꯥꯈꯂꯒꯤ ꯍꯀꯁꯦꯂꯒꯤꯗꯃꯛ ꯌꯥꯝꯅꯥ ꯃꯔꯨꯑꯣꯏ꯫
- ꯈꯣꯡꯆꯠ ꯑꯁꯤꯗꯥ ꯑꯗꯣꯝ ꯈꯛꯇꯒꯤ ꯅꯠꯇꯦ ꯍꯥꯌꯕꯥ ꯅꯤꯡꯁꯤꯡꯕꯤꯌꯨ꯫ ꯑꯆꯨꯝꯕꯥ ꯃꯦꯗꯤꯀꯦꯜ ꯇꯤꯃꯒꯤ ꯂꯃꯖꯤꯡ ꯃꯈꯥꯗꯥ, ꯅꯍꯥꯛꯅꯥ ꯀꯟꯗꯤꯁꯟ ꯑꯁꯤꯒꯥ ꯂꯣꯌꯅꯅꯥ ꯃꯥꯌꯄꯥꯛꯅꯥ ꯍꯤꯡꯕꯥ ꯉꯃꯒꯅꯤ꯫
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