Vuto lomwe anthu ambiri ali nalo masiku ano ndi kuthamanga kwa magazi, kapena monga tonse tikudziwira, 'kupanikizika'. Chifukwa chake, monga chithandizo cha izi, madokotala amalemba mitundu yosiyanasiyana ya mankhwala. Limodzi mwa iwo ndi mankhwala apadera otchedwa Aliskiren. Mwina inunso mwapatsidwa mankhwala awa. Lero, tiyeni tikambirane mwachidule komanso mwaubwenzi za mapiritsi a Aliskiren awa, zinthu zomwe muyenera kusamala nazo mukamawagwiritsa ntchito, komanso zotsatirapo zake zomwe zingachitike.
Aliskiren ndi chiyani?
Mwachidule, Aliskiren ndi mtundu wapadera wa mankhwala omwe amagwiritsidwa ntchito poletsa kuthamanga kwa magazi. Ndi m'gulu la mankhwala otchedwa 'renin inhibitors.' Tsopano mwina mukudabwa kuti 'renin' iyi imatanthauza chiyani.
Tangoganizirani, thupi lathu lili ndi dongosolo lachilengedwe lomwe limalamulira kuthamanga kwa magazi. Enzyme yomwe imagwira ntchito yofunika kwambiri mu dongosololi imatchedwa 'renin'. Nthawi zina, pamene enzyme iyi ya renin ikugwira ntchito kwambiri, mitsempha yamagazi imachepa (imangika) ndipo kuthamanga kwa magazi kumawonjezeka. Chifukwa chake chomwe Aliskiren amachita ndikulamulira mwachindunji ntchito ya enzyme ya renin imeneyo. Kenako mitsempha yamagazi imakhala yomasuka pang'ono, yokulirapo, ndipo kuthamanga kwa magazi kumachepa. Iyi ndiye ntchito yoyambira ya mankhwalawa.
Mankhwalawa amapezeka m'mafakitale osiyanasiyana ku Sri Lanka komanso padziko lonse lapansi. Limodzi mwa mankhwala otchuka kwambiri ndi `Tekturna`.
Zinthu zomwe muyenera kuuza dokotala wanu musanayambe kumwa mankhwalawa
Dokotala wanu asanapereke mankhwala kwa Aliskiren, adzakufunsani zinthu zingapo. Koma nthawi zina timaiwala kutchula zinthuzi. Choncho muyenera kuuza dokotala wanu za zinthuzi.
- Ngati muli ndi matenda a shuga: Izi ndizofunikira kwambiri. Muyenera kusamala kwambiri popereka mankhwala awa kwa munthu wodwala matenda a shuga.
- Ngati muli ndi matenda a impso: Ngati muli ndi matenda aliwonse a impso, muyenera kuwatchula.
- Ngati mwataya madzi m'thupi: Kungakhale koopsa kumwa mankhwalawa ngati mwataya madzi m'thupi ndipo thupi lanu lilibe madzi okwanira.
- Ngati muli ndi pakati kapena mukufuna kutenga mimba: Izi ndizofunikira kwambiri . Ngati muli ndi pakati kapena mukukonzekera kukhala ndi mwana posachedwa, muyenera kuuza dokotala wanu. Mankhwalawa akhoza kuvulaza kwambiri mwana wosabadwa.
- Kuyamwitsa: Ngati ndinu mayi woyamwitsa, tchulaninso zimenezo.
- Matenda Ena a Ziwengo: Ndikofunikira kutiuza ngati muli ndi vuto lililonse la ziwengo, osati la Aliskiren lokha, komanso la mankhwala ena aliwonse, chakudya, kapena utoto.
Njira yolondola yogwiritsira ntchito mankhwala
Ndikofunikira kwambiri kugwiritsa ntchito mlingo woyenera, monga momwe dokotala wanenera.
- Imwani panthawi yoyenera: Khalani ndi chizolowezi chomwa mankhwala anu nthawi yomweyo tsiku lililonse. M'mawa, m'mawa, ndi madzulo, nthawi yomweyo usiku uliwonse. Izi zithandiza kuti mankhwalawo akhale ndi mphamvu yofanana m'thupi.
- Muli ndi chakudya kapena ayi: Mutha kumwa mankhwalawa muli ndi chakudya kapena ayi. Koma chofunika kwambiri ndichakuti mumwa mofanana tsiku lililonse. Mwachitsanzo, ngati mumwa mutatha kudya chakudya cham'mawa tsiku lililonse, pitirizani kumwa mwanjira imeneyo. Musamwe musanayambe kudya chakudya cham'mawa tsiku lina ndipo mutatha kudya chakudya cham'mawa tsiku lotsatira.
- Musasiye kumwa mpaka dokotala wanu atakuuzani kuti: Musasiye kumwa mankhwala anu popanda kufunsa dokotala wanu, chifukwa choti mukuganiza kuti mukumva bwino tsopano ndipo kuthamanga kwa magazi anu ndi kwabwinobwino. Pitirizani kumwa.
Kodi mumatani ngati mwaphonya nthawi yokumana ndi dokotala?
Nthawi zina timaiwala kumwa mankhwala athu. Ngati taphonya mlingo, imwani mwamsanga tikangokumbukira. Komabe, ngati nthawi yatsala pang'ono yoti titenge mlingo wotsatira (monga, mkati mwa maola ochepa), dumphani mlingo womwe mwaphonya ndikumwa mlingo wotsatira panthawi yomwe yakonzedwa. Musamwe milingo iwiri nthawi imodzi.
Nanga bwanji ngati nditamwa mankhwala ochulukirapo?
Ngati mwadzidzidzi mukuganiza kuti mwamwa mankhwala ochulukirapo, musachite mantha ndipo nthawi yomweyo imbani National Poisons Information Centre ku Colombo National Hospital . Kapena pitani ku Emergency Treatment Unit (ETU) ya chipatala chapafupi.
Mankhwala ena omwe angagwirizane ndi Aliskiren
Mankhwala ena omwe mumamwa angagwirizane ndi Aliskiren, kuonjezera kapena kuchepetsa mphamvu yake, kapena kuyambitsa zotsatirapo zake. Choncho uzani dokotala wanu za mankhwala onse omwe mumamwa.
| Mtundu wa mankhwala | Zinthu zoti muzisamala nazo |
|---|---|
| Mankhwala ena othamanga magazi | Sikoyenera kumwa izi pamodzi ndi mankhwala ena othamanga magazi (makamaka kwa odwala matenda a shuga). |
| Zakudya zowonjezera potaziyamu | Kutenga izi pamodzi kungayambitse kuchuluka kwa potaziyamu m'magazi moopsa. |
| Zinthu zolowa m'malo mwa mchere zokhala ndi potaziyamu | Izi zilinso ndi potaziyamu wambiri, choncho musagwiritse ntchito popanda upangiri wa dokotala. |
| Atorvastatin (mankhwala ochepetsa cholesterol) | Pakhoza kukhala kuyanjana pakati pa mankhwala awiriwa. |
| Furosemide (mankhwala ochotsa madzi m'thupi) | Aliskiren ingachepetse mphamvu ya Furosemide. |
| Ketoconazole (mankhwala opha mabakiteriya) | Izi zitha kuwonjezera kuchuluka kwa Aliskiren m'thupi. |
Chofunika kwambiri: Ngati muli ndi matenda a shuga, ndipo mukumwa kale mankhwala ena othamanga magazi ochokera ku ARB (angiotensin-receptor-blocker) kapena ACE inhibitor (angiotensin-converting-enzyme-inhibitor) (monga Losartan, Telmisartan, Enalapril, Ramipril), musamwe Aliskiren pazifukwa zilizonse. Matendawa angayambitse kuwonongeka kwakukulu kwa impso. Onetsetsani kuti mwalankhula ndi dokotala wanu za izi.
Zotsatirapo zomwe zingakhalepo chifukwa cha mankhwalawa
Monga mankhwala ena aliwonse, Aliskiren ingayambitse mavuto ena mwa anthu ena. Zina mwa izi ndi zoopsa, pomwe zina ndi zochepa.
| Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala nthawi yomweyo | |
|---|---|
| Matenda a ziwengo | Kutupa pakhungu, kuyabwa, kutupa kwa milomo, lilime, nkhope kapena pakhosi. |
| Kuvuta kupuma | Kuvuta kupuma, kulimba pachifuwa. |
| Kusintha kwa kugunda kwa mtima | Kumva ngati mtima wanu ukugunda mofulumira kapena mosinthasintha. |
| Chizungulire kapena mutu wopepuka | Kumva ngati udzudzu, maso akusanduka abuluu, akugwa. |
| Mavuto a impso | Kuchepa kwa mkodzo, kupweteka pokodza. |
| Zina | Malungo, kupweteka pakhosi, kupweteka kwa gout, dzanzi m'miyendo. |
| Kawirikawiri si nkhani yaikulu (koma uzani dokotala ngati ikupitirira) | |
| Kuwawa kwam'mimba | Kupweteka m'mimba, kutsegula m'mimba. |
| Mutu | Mutu wochepa. |
| Chifuwa | Anthu ena akhoza kukhala ndi chifuwa chouma. |
| Kutopa | Kumva kutopa kwambiri kuposa masiku onse. |
Kodi mumasunga bwanji mankhwala moyenera?
- Sungani kutali ndi ana: Nthawi zonse sungani mankhwala pamalo otetezeka, kutali ndi ana ndi ziweto.
- Kutentha koyenera:Ndi bwino kusunga pamalo otentha (pakati pa 20-25 Celsius). Tetezani ku kutentha kwambiri ndi chinyezi.
- Tsekani botolo mwamphamvu: Sungani pakamwa pa botolo la mankhwala kapena paketi yotsekedwa bwino. Musachotse paketi yaying'ono (paketi ya silica gel) mkati mwa botolo. Imayamwa chinyezi kuchokera ku mankhwalawo ndikusunga kuti ikhale youma.
- Tayani mankhwala akatha ntchito: Onani tsiku lotha ntchito pa mankhwala ndipo tayani mankhwala aliwonse omwe atha ntchito popanda kuwagwiritsa ntchito.
Uthenga Wopita Nawo Kunyumba
- Aliskiren ndi mankhwala omwe ali mgulu la mankhwala otchedwa 'renin inhibitor' omwe amagwiritsidwa ntchito pochiza kuthamanga kwa magazi.
- Musanayambe kumwa mankhwalawa, uzani dokotala wanu za matenda anu onse (makamaka matenda a shuga, matenda a impso) ndi mankhwala ena onse omwe mukumwa.
- Ngati muli ndi matenda a shuga ndipo mukumwa mankhwala ena ochepetsa kuthamanga kwa magazi ochokera ku gulu la ARB kapena ACE inhibitor, musamwe Aliskiren.
- Pewani kugwiritsa ntchito mankhwalawa panthawi ya mimba kapena mukamayesa kutenga pakati. Uzani dokotala wanu nthawi yomweyo.
- Imwani mankhwala anu nthawi yomweyo komanso mofanana tsiku lililonse. Pewani kusiya kumwa mankhwala anu popanda kufunsa dokotala wanu.
- Fufuzani thandizo lachipatala mwamsanga ngati mukukumana ndi mavuto aakulu monga kutupa kwa nkhope, milomo, kapena kupuma movutikira.
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