Kodi mukukumana ndi vuto lachilendo la nyama yofiira? Tiyeni tiphunzire za Alpha-gal Syndrome!

Kodi munayamba mwadzifunsapo chifukwa chake mungakhale ndi zizindikiro za ziwengo mutadya nyama yofiira monga ng'ombe, nkhumba, kapena mbuzi? Mwina mudzayamba kutupa, kapena mudzayamba kuvutika m'mimba, kapena mudzavutika kupuma. Zingamveke zachilendo, koma n'zotheka. Lero tikambirana za ziwengo zachilendo, koma zofunika kwambiri. Zimatchedwa Alpha-gal Syndrome.

Kodi Alpha-gal Syndrome ndi chiyani? Tiyeni timvetse mosavuta!

Mwachidule, Alpha-gal Syndrome (AGS) ndi mtundu woopsa komanso wosazolowereka wa ziwengo pa chakudya womwe umachitika mukadya nyama yofiira ya nyama zoyamwitsa (monga ng'ombe, nkhumba, mbuzi, nyama yamphongo). Nthawi zambiri imayamba mutalumidwa ndi mitundu ina ya nkhupakupa, makamaka ngati mwalumidwa kangapo. Monga mukudziwa, nkhupakupa ndi tizilombo tating'onoting'ono tomwe timalumikizana ndi nyama ndikuyamwa magazi awo.

Tsopano taonani, nkhupakupa zina zimakhala ndi molekyulu ya chakudya yotchedwa alpha-gal m'malovu awo. Pamene molekyulu iyi ya alpha-gal ilowa m'magazi mwathu titaluma nkhupakupa, ingapangitse thupi lathu kukhala losavuta kukhudzidwa ndi nyama yofiira. Chomwe chimachitika ndichakuti chitetezo chathu cha mthupi chimazindikira nyama yofiira ngati chinthu chovulaza thupi ndipo chimayamba kuchitapo kanthu motsutsana nayo. Monga mdani. Ndicho chimayambitsa zizindikiro za ziwengo. Anthu omwe ali ndi AGS akhoza kukhala ndi ziwengo osati nyama yofiira yokha, komanso zinthu zina zomwe zili ndi alpha-gal, mwachitsanzo, mankhwala ndi sopo.

Tsoka ilo, pakadali pano palibe mankhwala a AGS. Koma musadandaule. Mutha kugwira ntchito ndi dokotala wanu kuti mupeze njira zopewera zomwe zimayambitsa matendawa ndikukhalabe athanzi.

Kodi molekyulu iyi yotchedwa Alpha-gal ndi chiyani?

Alpha-gal ndi chakudya cham'thupi, kapena kuti molekyulu ya shuga, yomwe imapezeka m'maselo a nyama zambiri zoyamwitsa. Koma sichimapangidwa mwachibadwa m'thupi la munthu. Ndicho chifukwa chake matupi athu amakwiya akalumidwa ndi nkhupakupa.

Ndi zakudya ndi zinthu ziti zomwe zili ndi Alpha-gal?

Zinthu zomwe zingakhale ndi alpha-gal ndi izi:

• Nyama yofiira: Zinthu monga nkhumba, ng'ombe, kalulu, mwanawankhosa, mbuzi, njati, ndi nyama ya ng'ombe.
• Mankhwala ndi mankhwala: Mwachitsanzo, mankhwala a Cetuximab, omwe amagwiritsidwa ntchito pochiza khansa.
• Zinthu zopangidwa kuchokera ku nyama zoyamwitsa: gelatin, mkaka wa ng'ombe, komanso sopo, mafuta odzola, ndi zinthu zapakhomo zingakhale ndi izi.

Tangoganizirani, ngakhale ayisikilimu kapena tchizi chomwe mumadya chingakhale ndi alpha-gal pang'ono. Choncho muyenera kusamala kwambiri.

Komanso, anthu ena omwe ali ndi matenda a shuga amatha kukhudzidwa ndi zinthu zomwe zili ndi chinthu chotchedwa carrageenan. Carrageenan ndi chinthu chomwe nthawi zambiri chimagwiritsidwa ntchito kukhuthala ndikusunga zakudya. Chimapezeka mu zinthu monga mkaka wa mtedza, nyama, ndi yogati.

Ndani angadwale matenda a Alpha-gal?

Izi zingachitikire aliyense, ngakhale munthu amene sanakumanepo ndi vuto la nyama yofiira. Komabe, nthawi zambiri zimapezeka mwa akuluakulu.

Anthu omwe amakhala nthawi yayitali m'malo akunja komwe nkhupakupa zimapezeka kwambiri, monga m'minda ndi m'malo okhala ndi nkhalango, ali pachiwopsezo chachikulu chotenga matenda a AGS. Ku Sri Lanka, ndi bwinonso kuti iwo omwe amagwira ntchito m'malo monga m'nkhalango kapena m'mafamu omwe muli nyama adziwe izi.

Ndi nkhupakupa zamtundu wanji zomwe zimayambitsa AGS?

Ku United States, nkhupakupa ya nyenyezi yokha ndiyo nkhupakupa yodziwika kwambiri yokhudzana ndi AGS. Komabe, pali mitundu ina ya nkhupakupa yomwe ingayambitse izi m'malo osiyanasiyana padziko lapansi. Mwachitsanzo:

• Nkhuku ya Blacklegged ku America
• "Cayenne tick" ku Central America
• Nkhuku ya ku Asia yokhala ndi nyanga yaitali ku Asia

Chofunika kwambiri ndi kusamala ngati mwalumidwa ndi nkhupakupa iliyonse ndipo funsani upangiri wa dokotala ngati pakufunika kutero.

Kodi pali mayina ena a matenda a Alpha-gal awa?

Inde, ili ndi mayina ena angapo:

• Matenda a Alpha-gal
• Matenda a nyama ya mammaly
• Matenda a nyama yofiira
• Kuluma nyama chifukwa cha ziwengo

Kodi n’chiyani chimayambitsa matenda a Alpha-gal? N’chifukwa chiyani zimenezi zimachitika?

Vutoli linayamba kufotokozedwa mu 2009. Limayamba chifukwa cha kuluma kwa nkhupakupa zomwe zimakhala ndi molekyulu yotchedwa alpha-gal m'malovu awo. Ngakhale kuti ziwengo zina zambiri za chakudya zimayambitsidwa ndi mapuloteni, izi zimachitika chifukwa cha molekyulu ya carbohydrate (shuga), kotero zimatenga nthawi kuti vutoli liwonekere. Izi zikutanthauza kuti zizindikiro nthawi zambiri zimawonekera pakati pa maola awiri ndi asanu ndi limodzi mutadya nyama yofiira . Izi zikuganiziridwa kuti zimachitika chifukwa chakuti matupi athu amatenga nthawi yayitali kuti chakudya chigayidwe kuposa mapuloteni.

Madokotala sakudziwabe chifukwa chake alpha-gal iyi imayambitsa kukhudzidwa ndi nyama yofiira kapena mankhwala a khansa omwe atchulidwa pamwambapa a Cetuximab. Mofananamo, chifukwa chomwe anthu ena amakhalira ndi AGS pomwe ena samakhala nacho chikufufuzidwabe.

Kodi zizindikiro za Alpha-gal Syndrome ndi ziti?

Zizindikiro za izi zimatha kusiyana kwambiri. Anthu ena akhoza kukhala ndi zizindikiro zochepa kwambiri, pomwe ena akhoza kukhala ndi zizindikiro zoopsa zomwe zingawopseze moyo.

Zomwe zimachitika kwambiri pakhungu ndi izi:

• Kuyabwa kwambiri pakhungu (madokotala amatcha kuti pruritus)
• Kufiira kwa khungu ndi kutupa (komwe kumatchedwanso kufinya)
• Matuza pakhungu, matuza omwe amaoneka ngati nthenda ya nkhuku (izi zimatchedwa urticaria kapena hives)
• Kutupa kwa milomo, zikope, pakhosi, lilime, kapena nkhope (izi zimatchedwa angioedema)

Mavuto a m'mimba amathanso kuchitika, nthawi zina izi zokha:

• Kupweteka m'mimba, kupweteka m'mimba
• Kutsegula m'mimba
• Kutentha pamtima, kusadya bwino
• Kusagaya chakudya, kusagaya chakudya (dyspepsia)
• Kupweteka kwa minofu
• Kusanza kapena kusanza

Matenda a Alpha-gal angayambitsenso zizindikiro zokhudzana ndi mapapo. Izi ndi zoopsa kwambiri:

• Anaphylaxis: Ichi ndi choopsa kwambiri. Matenda oopsa omwe angalepheretse kupuma komanso kupha munthu. Ngati mukuvutika kupuma, pitani kuchipatala chapafupi nthawi yomweyo kapena imbani 911.
• Chifuwa
• Kuvuta kupuma, kupuma movutikira (dyspnea)
• Kupuma movutikira

Pakhoza kukhalanso zizindikiro zina:

• Matenda a nyamakazi (izi sizichitika kawirikawiri)
• Kugunda kwa mtima, kumva ngati chifuwa chanu chikugunda
• Kuthamanga kwa magazi pang'ono (hypotension)
• Matenda a mast cell activation syndrome, matenda osowa chitetezo chamthupi (komanso osowa)

Kodi pali zinthu zina zomwe zimakhudza zizindikiro?

Inde, zizindikiro zanu zimatha kusintha pakapita nthawi. Matenda a ziwengo amatha kukhala oopsa kwambiri kapena kuchitika pafupipafupi ngati mwalumidwa ndi nsikidzi yatsopano. Nthawi zina, zinthu monga kumwa mowa, kuchita masewera olimbitsa thupi, komanso kuchita masewera olimbitsa thupi zingakhudzenso momwe thupi lanu limayankhira ku alpha-gal.

N’chifukwa chiyani matenda a Alpha-gal ndi ovuta kuwazindikira?

Izi zingakhale zovuta kuzizindikira. Pali zifukwa zingapo.

Chimodzi ndi chakuti nkhupakupa sizimva kupweteka zikaluma, kotero anthu ambiri sadziwa ngakhale kuti zalumidwa ndi nkhupakupa.

Komanso, mosiyana ndi ziwengo zina za chakudya, kuyankhidwa ndi alpha-gal kumatenga maola ambiri kuti kuwonekere . Nthawi zina zizindikiro zimawonekera pakati pausiku mutadya chakudya chamadzulo. Ndani angaganize kuti izi zinachitika chifukwa cha nyama yomwe adadya m'mawa kapena nthawi ya nkhomaliro?

Komanso, si nthawi zonse pamene alpha-gal yamezedwa, pamakhala zotsatirapo, ndipo zizindikiro sizimawonekera mofanana nthawi zonse.

Chifukwa cha zinthu izi, zingakhale zovuta pang'ono kwa inu ndi dokotala wanu kudziwa ngati izi sizili choncho kupatula alpha-gal.

Kodi madokotala amazindikira bwanji izi?

Kuti adziwe matenda a AGS, dokotala wanu kapena katswiri wa ziwengo adzayang'anitsitsa zizindikiro zanu, mbiri yanu yachipatala, ndi kuyezetsa thupi lanu. Kuphatikiza apo, kuyezetsa ziwengo kungachitike kuti atsimikizire matendawa. Zofunikira kwambiri ndi izi:

• Kuyezetsa magazi: Izi zimayang'ana kupezeka kwa ma immunoglobulin-E antibodies (IgE) m'magazi, omwe chitetezo chathu cha mthupi chimapanga motsutsana ndi alpha-gal.
• Kuyesa kubaya pakhungu: Pa izi, kuchuluka pang'ono kwa zinthu zomwe zimayambitsa ziwengo kumayikidwa pamwamba pa khungu kuti awone ngati pali zomwe zimachitika.

Ngati mukuganiza kuti muli ndi matenda a AGS, pitani kwa dokotala mwamsanga. Mukazindikira msanga, zimakhala zosavuta kupewa zinthu zomwe zimayambitsa ziwengo komanso kupewa mavuto.

Kodi pali mankhwala athunthu a izi?

Monga tanenera kale, pakadali pano palibe mankhwala a Alpha-gal Syndrome. Koma musadandaule. Ngati yapezeka msanga, inu ndi dokotala wanu mungagwire ntchito limodzi kuti mupange dongosolo loyang'anira lomwe likugwirizana ndi zosowa zanu.

Kodi izi zimachiritsidwa bwanji?

Chithandizo chachikulu cha munthu amene ali ndi matenda a shuga ndi kupewa zakudya ndi zinthu zomwe zili ndi alpha-gal . Kuphatikiza apo, mankhwala amaperekedwa kuti achepetse zizindikiro ngati chinthu chonga ichi chatengedwa mwangozi.

Madokotala angakulangizeni mankhwala monga antihistamines kapena adrenaline injector ngati mugwiritsa ntchito mwadzidzidzi. Pa milandu yoopsa monga anaphylaxis, epinephrine injector iyi ikhoza kupulumutsa moyo. Mankhwala ena amadalira zizindikiro zanu. Mwachitsanzo, mankhwala opangidwa ndi cromolyn angathandize ndi mavuto am'mimba.

Kodi ndingachepetse bwanji chiopsezo chotenga matenda a Alpha-gal?

Njira yabwino yodzitetezera ku matenda a AGS okha, komanso matenda ena ofalitsidwa ndi nkhupakupa, ndi kupewa kulumidwa ndi nkhupakupa . Pali zinthu zingapo zomwe mungachite kuti muchite izi:

• Pewani malo omwe kuli nkhupakupa: Pewani kuyenda mosafunikira m'nkhalango, m'malo okhala ndi udzu, komanso m'malo okhala ndi mitengo yambiri, makamaka komwe kuli nyama. Samalaninso mukamagwira ntchito m'munda.
• Phimbani bwino: Valani zovala za manja aatali, mathalauza aatali. Ikani masokosi pamwamba pa mathalauza anu, valani nsapato. Ngati n'kotheka, gwiritsani ntchito chipewa ndi magolovesi.
• Gwiritsani ntchito mankhwala othamangitsa tizilombo: Gwiritsani ntchito mankhwala oletsa tizilombo ovomerezeka ndi madokotala. Ena akhoza kupakidwa pa zovala. Mankhwala okhala ndi permethrin akhoza kupakidwa pa zovala.
• Yang'anani nkhupakupa (Yang'anani nkhupakupa):Mukabwerera kuchokera panja, dzifufuzeni nokha ndi ziweto zanu ngati muli ndi nkhupakupa. Ndi bwinonso kusamba.
• Ngati muwona nkhupakupa, ichotseni mwachangu: Gwiritsani ntchito ma tweezers kuti mugwire mutu kapena pakamwa pa nkhupakupa, ndipo muikoke mosamala mmwamba popanda kuiphwanya. Kenako ikani mankhwala ophera tizilombo pamalopo.

Ngati muli ndi Alpha-gal Syndrome, ndi zakudya, zakumwa, ndi zinthu ziti zomwe muyenera kupewa?

Anthu ambiri omwe ali ndi matenda a shuga ayenera kupewa kwathunthu nyama yofiira ndi zinthu zina zophikidwa ndi nyama yofiira. Komabe, si aliyense amene amakhudzidwa ndi alpha-gal mofanana. Choncho ndi bwino kulankhula ndi dokotala wanu kapena katswiri wa ziwengo kuti mudziwe chomwe chimakuyambitsani.

Zinthu zomwe muyenera kupewa nthawi zambiri ndi izi:

• Nyama yofiira: ng'ombe, nkhosa, mbuzi, nyama ya ng'ombe, kalulu, njati, nkhumba.
• Zinthu zopangidwa kuchokera ku nyama yofiira: zowonjezera zakudya, mkaka, kirimu, ayisikilimu, mafuta a nyama (nyama yankhumba), tchizi.
• Zinthu zosamalira khungu zopangidwa kuchokera ku nyama: zinthu zomwe zili ndi collagen, lanolin, gelatin, glycerin.
• Zinthu zina: Lankhulani ndi dokotala wanu za mankhwala aliwonse omwe mumamwa. Komanso, ma valve a mtima ochokera ku nkhumba kapena ng'ombe, maukonde ochitira opaleshoni, ndi katemera wina angayambitse ziwengo.

Kodi chidzachitike n’chiyani pambuyo pake? Kodi tidzakhala bwanji ndi izi?

Ngati mutsatira malangizo a dokotala wanu mosamala ndikupewa zinthu zomwe zimayambitsa ziwengo zanu, mutha kukhala bwino ndi AGS. Dokotala wanu adzakuthandizani kupeza njira zochepetsera chiopsezo chanu cha ziwengo.

Chofunika kwambiri ndikuchitapo kanthu kuti mupewe kuluma nkhupakupa , chifukwa kuluma nkhupakupa mobwerezabwereza kungapangitse kuti ziwengo zikhale zovuta kwambiri.

Kodi muyenera kufunsa upangiri wa dokotala liti?

Ngati mukumva zizindikiro za AGS, pitani kwa dokotala wa ziwengo kapena dokotala wamba nthawi yomweyo kuti mupange dongosolo la chithandizo lomwe likugwirizana ndi inu.

Uthenga Wopita Nawo Kunyumba

Chabwino, ndiye kuti Alpha-gal Syndrome (AGS) yomwe takambirana lero ndi vuto lalikulu la ziwengo ku nyama yofiira yomwe imayamba chifukwa cha kulumidwa ndi nkhupakupa. Zingakhale zovuta kuzizindikira, chifukwa zizindikiro zimawonekera patatha maola angapo. Ndipo pakadali pano palibe mankhwala ake.

Koma musadandaule! Ngati muzindikira msanga, tsatirani malangizo a dokotala wanu, pewani zakudya ndi zinthu zovulaza, komanso dzitetezeni ku nkhupakupa, inunso mutha kukhala ndi thanzi labwino. Ngati muli ndi zizindikiro izi, onetsetsani kuti mwaonana ndi dokotala.

'Matenda a Alpha-gal, Matenda a nyama yofiira, Matenda obadwa ndi nkhupakupa, Matenda a chakudya, Zizindikiro za ziwengo, Chitetezo ku nkhupakupa