Kodi muli ndi mphumu? Mwina mukugwiritsa ntchito mankhwala anu opumira monga momwe mwalangizidwira ndipo mukumwa mankhwala ena, koma zizindikiro zanu za mphumu sizikuchepa. Ngati mukumva kupuma movutikira, kupsinjika pachifuwa, komanso kukhosomola, mwina muli ndi mphumu yapakati mpaka yoopsa. Njira yatsopano yochiritsira iyi, yotchedwa 'Biologic Therapy', imagwiritsidwa ntchito pa matenda a mphumu ovuta kuwalamulira.
Mwachidule, kodi Biologic Therapy ndi chiyani?
Uwu ndi mankhwala amakono komanso ofunikira kwambiri a mphumu yoopsa. Ngakhale kuti mankhwala opumira nthawi zonse amakulitsa njira zopumira kwakanthawi ndikupangitsa kupuma kukhala kosavuta, chithandizo chamankhwala cha biologic chimapita patsogolo kwambiri.
Tangoganizirani, chifukwa chachikulu chomwe chimayambitsa mphumu ndi kutupa m'njira zopumira zomwe zimachitika chifukwa cha ntchito ina ya chitetezo chamthupi. Chifukwa chake mankhwala awa amagwira ntchito yolimbana ndi ma antibodies, maselo kapena mamolekyu enaake m'thupi omwe amathandizira kutupako ndikuyimitsa ntchito yawo. Chifukwa cha izi, mphumu imayendetsedwa pamlingo woyambira.
Chithandizochi chimaperekedwa m'njira ziwiri zazikulu: Choyamba ndi jakisoni pansi pa khungu (jakisoni wa subcutaneous) ndipo china ndi jakisoni wa m'mitsempha (IV infusion).
Chofunika kwambiri ndichakuti iyi si njira yokhayo yochiritsira. Iyenera kugwiritsidwa ntchito limodzi ndi mankhwala omwe alipo kale a inhaler ndi mankhwala ena a mphumu.
Kodi chithandizochi n'choyenera kwa ndani?
Chithandizo cha biologic si chithandizo cha odwala onse a mphumu. Dokotala wanu adzaganizira zinthu zingapo asanakulimbikitseni chithandizochi. Tebulo ili pansipa likupatsani lingaliro labwino.
| Zochitika zomwe mungatumizidwe ku Biologic Therapy | |
|---|---|
| Sizimayang'aniridwa ndi mankhwala olembedwa ndi dokotala | Ngati zizindikiro zanu za mphumu sizikuthetsedwa ngakhale mutagwiritsa ntchito inhaler yanu yolembedwa ndi mankhwala ena molondola. |
| Zotsatira za mayeso a magazi | Ngati muli ndi kuchuluka kwa ma Eosinophils (selo loyera la magazi lomwe limayambitsa kutupa m'mapapo) kapena IgE (antibody yokhudzana ndi ziwengo) m'magazi anu. |
| Zifukwa zomwe zimayambitsa matendawa | Ngati mukudziwa chomwe chimayambitsa mphumu yanu ndipo pewani, koma zizindikiro zikupitirira. |
| Zizindikiro zofala | Ngati mudzuka pakati pa usiku muli ndi chifuwa, kapena ngati mugwiritsa ntchito chopumira chanu chopulumutsa anthu okalamba kuposa kawiri pa sabata. |
| Kuwonjezeka kwafupipafupi | Ngati mukuyenera kumwa mapiritsi a corticosteroid kangapo pachaka kapena kupita ku ETU (Emergency Treatment Unit). |
| Kugonekedwa m'chipatala | Ngati muyenera kukhala m'chipatala ndi kulandira chithandizo chifukwa cha mphumu. |
Ndi mitundu iti ya mankhwala achilengedwe omwe alipo a mphumu?
Pali mitundu ingapo ya mankhwala achilengedwe omwe avomerezedwa mpaka pano. Iliyonse imagwira ntchito mosiyana pang'ono. Dokotala wanu adzakusankhirani mankhwala oyenera kutengera mtundu wanu wa mphumu komanso zotsatira za mayeso a magazi.
| Dzina la mankhwala | Ntchito ndi njira yoperekera | Zotsatira zoyipa zofala |
|---|---|---|
| Omalizumab (Xolair®) | Amachiritsa mphumu yomwe imayamba chifukwa cha ziwengo. Amabayidwa pansi pa khungu milungu iwiri kapena inayi iliyonse. | Kupweteka kwa minofu, kupweteka kwa mafupa, kutopa kwambiri, kutupa/kupweteka pamalo omwe jakisoni amaperekedwa. |
| Mepolizumab (Nucala®) | Amachiritsa mphumu ya eosinophilic. Amabayidwa pansi pa khungu milungu inayi iliyonse. | Mutu, kupweteka kwa msana, kufooka, kutopa, kutupa/kupweteka pamalo omwe jakisoni amaperekedwa. |
| Reslizumab (Cinqair®) | Amachiritsa mphumu ya eosinophilic. Amaperekedwa kudzera m'mitsempha (IV) milungu inayi iliyonse. | Kupweteka pakhosi, kupweteka kwa minofu. |
| Benralizumab (Fasenra®) | Amachiritsa mphumu ya eosinophilic. Mlingo woyamba wa mankhwala atatu umaperekedwa milungu inayi iliyonse, kenako milungu isanu ndi itatu iliyonse. | Mutu, pakhosi. |
| Dupilumab (Dupixent®) | Amachiritsa mphumu ya eosinophilic ndi matenda ena omwe amayamba chifukwa cha kutupa. Amabayidwa jakisoni milungu iwiri iliyonse. | Kupweteka pakhosi, kutupa/kupweteka pamalo obayira jakisoni, kuchuluka kwa maselo oyera m'magazi. |
| Tezepelumab (Tezspire®) | Mankhwala atsopano a mphumu yoopsa. Amachepetsa kutupa. Amabayidwa milungu inayi iliyonse. | Kupweteka pakhosi, kupweteka msana, kupweteka m'mafupa. |
Kodi chithandizochi chimatenga nthawi yayitali bwanji?
Kawirikawiri chithandizochi chimakhala cha nthawi yayitali. Zingatenge miyezi 4-6 kuti mudziwe ngati mankhwalawa akukuthandizani. Choncho ndikofunikira kukhala oleza mtima ndi chithandizo chanu.
Kodi ndiyenera kupitiriza kugwiritsa ntchito inhaler yanga?
Inde, ndithudi.Ichi ndi chinthu chofunikira kwambiri. Ngakhale mutayamba kugwiritsa ntchito mankhwala a biologic, musasiye kumwa mankhwala anu opumira ndi mankhwala ena omwe dokotala wanu wakupatsani. Pakapita nthawi, ngati mphumu yanu yayamba kulamulira bwino, dokotala wanu angasankhe kuchepetsa mlingo wa mankhwala anu opumira. Koma izi ziyenera kuchitika pokhapokha ngati dokotala akupatsani upangiri.
Kodi ubwino ndi zoopsa za chithandizochi ndi ziti?
Monga chithandizo chilichonse, ichi chili ndi ubwino komanso zoopsa zazing'ono.
Ubwino waukulu:
- Amachepetsa kutupa m'njira yopumira komanso amaletsa bwino zizindikiro za mphumu.
- Chimfine ndi chifuwa chobwerezabwereza zidzachepa.
- Mudzatha kuchita masewera olimbitsa thupi ndikumaliza ntchito za tsiku ndi tsiku popanda kugwira ntchito molimbika monga kale.
- Kuchuluka kwa nthawi zomwe mumadzuka usiku kumachepa.
- Kufunika kopita ku ETU (Emergency Treatment Unit) kawirikawiri kudzachepa.
- Moyo wabwino ukupita patsogolo kwambiri.
Zoopsa zomwe zingachitike:
- Matenda oopsa a ziwengo: Nthawi zambiri, anthu ena amatha kukhala ndi vuto lalikulu la ziwengo (anaphylaxis). Ichi ndichifukwa chake mlingo woyamba umaperekedwa kuchipatala kapena kuchipatala moyang'aniridwa ndi dokotala.
- Kuopsa kwa matenda opatsirana ndi tizilombo toyambitsa matenda: Mankhwala omwe amachepetsa ma eosinophils angachepetse pang'ono mphamvu ya thupi yolimbana ndi tizilombo toyambitsa matenda, makamaka helminths. Choncho dokotala wanu adzaganizira zimenezo asanayambe chithandizochi.
Chofunika: Musasiye kumwa mankhwalawa mwadzidzidzi pazifukwa zilizonse popanda upangiri wa dokotala. Kuchita zimenezi kungapangitse kuti zizindikiro za mphumu yanu ziwonjezeke.
Nthawi yoti mulankhule ndi dokotala wanu
Pazochitika zotsatirazi, onetsetsani kuti mwaonana ndi dokotala wanu ndikumudziwitsa.
- Ngati zizindikiro za mphumu sizikuchepa kapena sizikuipiraipira patatha miyezi ingapo ya chithandizo.
- Ngati zizindikiro zatsopano za ziwengo (monga ziphuphu pakhungu, kuyabwa) zikuwonekera.
- Ngati muli ndi mafunso kapena nkhawa zokhudzana ndi chithandizochi.
Chithandizochi chingapezeke potsatira malangizo a dokotala wapadera, kuchokera ku chipinda chapadera cha chipatala (malo operekera mankhwala) kapena kuchokera ku chipatala cha dokotala wapadera. Chithandizochi chingakhale chokwera mtengo pang'ono. Koma mutha kulankhula ndi dokotala wanu za izi ndikupeza zambiri.
Uthenga Wopita Nawo Kunyumba
- Biologic Therapy ndi njira yapamwamba yochiritsira yomwe imagwiritsidwa ntchito pa matenda aakulu a mphumu omwe ndi ovuta kuwathetsa ndi mankhwala wamba.
- Iyi si mankhwala a mphumu, koma imathandiza kulamulira matendawa bwino kwambiri.
- Mukamalandira chithandizochi, ndikofunikira kupitiriza kugwiritsa ntchito inhaler yanu ndi mankhwala ena onse omwe dokotala wanu wakupatsani.
- Kaya chithandizochi chili choyenera kwa inu kapena ayi chidzadziwika mutaganizira zizindikiro zanu komanso malipoti enaake a magazi.
- Popeza zingatenge miyezi ingapo kuti zotsatira za chithandizo ziwonekere, ndikofunikira kwambiri kukhala oleza mtima ndikutsatira malangizo a dokotala panthawi ya chithandizo.
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