Kufotokozera kosavuta kwa ziphuphu zachilendo pa miyendo ndi m'manja: Tiyeni tiphunzire za Clear Cell Sarcoma.

Kodi mudayamba mwakhalapo ndi chotupa kapena chotupa chachilendo pansi pa khungu la mwendo kapena mkono wanu chomwe sichingachoke? Sichingapweteke ngakhale mukamachikanikiza. Koma ngati chikuwoneka ngati chikukulirakulira, chingakhale chinthu chodetsa nkhawa nacho. Lero tikambirana za khansa yosowa yomwe ingayambitse zizindikiro zofanana, koma ndikofunikira kudziwa. Imatchedwa Clear Cell Sarcoma .

Kodi Clear Cell Sarcoma ndi chiyani?

Mwachidule, clear cell sarcoma ndi khansa yosowa kwambiri yomwe imapezeka m'minofu yofewa . Imagwera m'gulu lotchedwa sarcoma . Nthawi zambiri, khansa imeneyi imayambira m'misempha , minofu yomwe imagwirizanitsa minofu ndi mafupa, ndi minofu yofewa yozungulira minofu, m'miyendo yanu, makamaka mapazi anu.

Monga mitundu ina ya khansa, clear cell sarcoma ndi yosavuta kuchiza ngati yapezeka isanafalikire mbali zina za thupi. Madokotala amachiritsa vutoli makamaka ndi opaleshoni , ndipo ngati pakufunika , chithandizo cha radiation ndipo nthawi zina chemotherapy . Tsoka ilo, ngakhale atalandira chithandizo, matendawa ali ndi mwayi waukulu wobwereranso. Ichi ndichifukwa chake ofufuza azachipatala nthawi zonse amafufuza njira zatsopano zochizira clear cell sarcoma.

Kodi clear cell sarcoma imakhudza bwanji thupi langa?

Matenda a Clear cell sarcoma nthawi zambiri amayamba m'minofu yofewa yozungulira minyewa ndi minofu yanu, kapena mu minofu yotchedwa fascia . Fascia ili ngati gulu lomwe limazungulira kapangidwe kalikonse m'thupi lathu.

Poyamba, simungazindikire chilichonse. Koma mudzazindikira khansa ikakula ndikukhala chotupa chomwe chingamveke pansi pa khungu la mwendo kapena phazi lanu. Chotupachi chingawoneke ngati chotupa chomwe chimawonekera mukagunda mwendo kapena phazi lanu mwamphamvu, koma kusiyana kwakukulu ndikuti chotupachi sichimachepa pakapita nthawi . Clear cell sarcoma imakula pang'onopang'ono. Komabe, ikafalikira kuchokera ku minofu yanu yofewa pansi pa khungu, mwina yayamba kale kufalikira ku ziwalo zina za thupi lanu.

Tangoganizirani, mwapeza chotupa chaching'ono pa mwendo wanu ndipo mwachinyalanyaza, mukuganiza kuti, "O, izi ziyenera kuti zangochitika kumene." Patatha milungu kapena miyezi ingapo, chimakhalabe, mwina chachikulu pang'ono. Pankhaniyi, ndibwino kwambiri kufunafuna upangiri wa dokotala.

Kodi clear cell sarcoma imafalikira kuti?

Sarcoma ya maselo oyera imatha kufalikira ku ziwalo zina za thupi, makamaka:

• Dongosolo lanu la m'mimba (njira ya m'mimba)
• YanuKu mapapo
• Dongosolo lanu la lymphatic , lomwe ndi ma lymph nodes ndi mitsempha ya lymph m'thupi lanu.

Kodi izi ndi vuto lofala?

Ayi, ayi konse. Iyi ndi mtundu wa khansa wosowa kwambiri. Ndipotu, sarcoma ndi mtundu wa khansa wosowa kwambiri. Mwachitsanzo, ku United States, anthu pafupifupi 1,600 amapezeka ndi sarcoma chaka chilichonse. Ndi chiwerengero chochepa, pafupifupi 1% ya khansa zonse mwa akuluakulu. Clear cell sarcoma, ndi 1% yokha ya sarcomas zonse. Kotero mutha kuganiza momwe izi zilili zachilendo.

Ndani amene ali ndi mwayi waukulu wokhala ndi sarcoma ya maselo omveka bwino?

Ngakhale kuti clear cell sarcoma imatha kufalikira pa msinkhu uliwonse, nthawi zambiri imapezeka mwa achinyamata azaka zapakati pa 15 ndi 40 , makamaka omwe ali ndi zaka zapakati pa 20 ndi 30.

Kodi zizindikiro za clear cell sarcoma ndi ziti?

Monga tanenera kale, chizindikiro chofala kwambiri ndi chotupa chomwe sichichoka pansi pa khungu la mwendo kapena phazi lanu . Chotupachi chingapweteke kapena sichingapweteke. Koma ngati chilipo ndipo chikumva ngati chikukulirakulira, chimenecho ndi chizindikiro chachikulu.

Kuphatikiza apo, zizindikiro zotsatirazi zitha kuwonekera pambuyo pake:

• Kutopa kwambiri popanda chifukwa
• Kuchepetsa thupi kosamveka bwino
• Thukuta la usiku

Kodi n’chiyani chimayambitsa matenda a clear cell sarcoma?

Izi ndi zovuta pang'ono. Ofufuza zachipatala apeza kuti clear cell sarcoma imayamba chifukwa cha magawo awiri a ma chromosome m'maselo athu omwe amasinthasintha malo, ndikupanga jini yatsopano yosakanikirana .

Mwachidule, izi ndi zomwe zimachitika:

Maselo a thupi lathu akamagawikana, nthawi zina ma chromosome awiri amasweka ndipo zidutswa zosweka zimasinthana. Pankhaniyi, zigawo za ma chromosome zomwe zimasinthidwa zimakhala ndi majini otchedwa EWSR1 ndi ATF1 . Puloteni yomwe imapangidwa ndi jini la EWSR1 imawoneka kuti ndi yofunika kwambiri pakugwira ntchito kwa maselo. Jini la ATF1 limathandiza kuwongolera kukula kwa maselo. Ma chromosome awa akabwereranso pamodzi, zigawo za majini zomwe zasinthidwa zimafika pamalo olakwika. Madokotala amatcha izi kuti ndi translocation yobwerezabwereza . Chifukwa chenicheni chomwe izi zimachitikira sichikudziwikabe.

Akasamutsidwira ku chromosome yatsopano, majini osinthidwa amasonkhana pamodzi kuti apange jini yosakanikirana yotchedwa EWSR1/ATF1 . Ofufuza amakhulupirira kuti jini yosakanikirana iyi ndiyo imayambitsa matenda a clear cell sarcoma.

Kodi madokotala amazindikira bwanji matenda a clear cell sarcoma?

Mukapita kwa dokotala yemwe ali ndi chotupa chonga chimenecho, choyamba adzakuyang'anirani ndikuwona komwe chotupacho chili, kukula kwake, ndi zina. Kenako mungafunike MRI scan (Magnetic Resonance Imaging - MRI).N'zotheka.

Komabe, kupezeka kwa clear cell sarcoma kumatsimikiziridwa ndi biopsy, yomwe imaphatikizapo kutenga chidutswa chaching'ono cha minofu kuchokera pa chotupacho . Pamene chitsanzo cha minofuchi chikuyang'aniridwa pogwiritsa ntchito maikulosikopu, akatswiri a matenda, akatswiri omwe amafufuza minofu mu labu, amafufuza kupezeka kwa jini yolumikizidwa ya EWSR1/ATF1 yomwe tidakambirana kale.

Kodi clear cell sarcoma imachiritsidwa bwanji?

Cholinga chachikulu cha madokotala ndikuletsa kuti sarcoma ya maselo oyera isafalikire mbali zina za thupi. Nthawi zambiri, gawo loyamba ndikuchita opaleshoni kuti chotupacho chichotsedwe kwathunthu . Ngati khansa yafalikira ku ma lymph node, ma lymph node amenewo amachotsedwanso. Izi zimatsatiridwa ndi chithandizo chowonjezera . Izi nthawi zambiri zimaphatikizapo chithandizo cha radiation kuti aphe maselo otsala a khansa.

Ofufuza zachipatala pakadali pano akufufuza njira zina zochizira matenda. Mwachitsanzo, akuyang'ana momwe chithandizo cha immunotherapy chilili chothandiza polimbana ndi clear cell sarcoma. Akuyesanso ngati mankhwala omwe akugwiritsidwa ntchito pochiza mitundu ina ya khansa angathandize kuletsa kufalikira kwa clear cell sarcoma.

Chofunika kwambiri ndichakuti clear cell sarcoma ndi vuto lomwe nthawi zambiri limatha kubwereranso. Ngati zimenezo zitachitika, mungafunike kuchitidwa opaleshoni yambiri komanso kulandira chithandizo cha radiation. Ndipo chifukwa chakuti imatha kufalikira mofulumira kwambiri, madokotala adzakuyang'anani nthawi zonse kuti awone ngati zotupa zatsopano zayamba.

Kodi ndingachepetse chiopsezo changa chokhala ndi clear cell sarcoma?

Mwatsoka, palibe chomwe mungachite kuti muchepetse chiopsezo chanu chotenga matendawa. Chifukwa ofufuza zachipatala sanazindikirebe zinthu zinazake zomwe zimayambitsa matenda a clear cell sarcoma. Choopsa ndi ntchito kapena vuto lomwe limawonjezera mwayi wopeza matenda.

Kodi sarcoma ya maselo oyera imatha kuchiritsidwa kwathunthu?

Madokotala amatha kuchiza clear cell sarcoma, zomwe zikutanthauza kuti amatha kuchotsa chotupacho ndikuyesera kuwongolera kufalikira kwake. Komabe, si vuto lochiritsika kwathunthu . Nthawi zambiri, clear cell sarcoma imatha kufalikira ku ziwalo zina za thupi panthawi yomwe yapezeka. Izi zimapangitsa kuti zikhale zovuta kuchiza. Komanso nthawi zambiri imatha kubwereranso pambuyo pa chithandizo.

Kodi munthu amene ali ndi clear cell sarcoma amakhala ndi moyo wautali bwanji?

Chiyembekezo cha moyo ndi kuyerekezera kwa nthawi yomwe mudzakhala ndi moyo, kutengera thanzi lanu lonse komanso zinthu zomwe muli nazo. Kuwunikanso kwa US National Cancer Database mu 2018 kunawonetsa kuti pakati pa anthu omwe ali ndi clear cell sarcoma,Inanenanso kuti 50% anali akadali ndi moyo zaka zisanu atapezeka ndi matendawa, ndipo 38% anali akadali ndi moyo zaka khumi atapezeka ndi matendawa .

Kaya tikulankhula za nthawi yoyembekezera moyo kapena kuchuluka kwa anthu omwe adzapulumuke, ndikofunikira kukumbukira kuti izi ndi ziwerengero chabe, osati zolosera. Nthawi yoyembekezera moyo ndi kuyerekezera kotengera anthu onse. Chiwerengero cha anthu omwe adzapulumuke khansa ndi ziwerengero zotengera nthawi yomwe anthu amakhala pambuyo polandira chithandizo cha khansa yamtundu winawake. Pali zinthu zambiri zomwe zingakhudze nthawi yomwe munthu adzakhala ndi moyo kapena mwayi wawo wopulumuka khansa. Ngati muli ndi clear cell sarcoma, dokotala wanu angakupatseni chidziwitso chabwino kwambiri cha zomwe mungayembekezere.

Kodi sarcoma ya maselo oyera ikhoza kupha?

Inde, zitha kupha. Kawirikawiri, anthu omwe sarcoma yawo yafalikira mbali zina za thupi amakhala ndi mwayi wofa msanga kuposa omwe amalandira chithandizo khansa isanafalikire.

Ndiyenera kupita kwa dokotala liti?

Popeza kuti clear cell sarcoma imatha kubwereranso mukalandira chithandizo, dokotala wanu angafune kukuonani miyezi itatu iliyonse kwa zaka ziwiri zoyambirira mutalandira chithandizo, kutengera vuto lanu. Ndikofunikira kuti muzipimidwa nthawi zonse pambuyo pake.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Clear cell sarcoma ndi matenda osowa kwambiri. Akhoza kukhala oopsa kwa moyo. Ngati mwapezeka ndi vutoli, mungafune kufunsa dokotala wanu mafunso awa:

• Kodi chotupacho chili kuti? Kodi ndi chachikulu bwanji?
• Kodi chotupacho chafalikira kwina kulikonse m'thupi langa?
• Kodi mumalimbikitsa chithandizo chanji?
• Kodi zotsatirapo zake ndi ziti?
• Ngati ndichitidwa opaleshoni, kodi mwayi woti chotupacho chibwererenso ndi wotani?
• Kodi pali mayesero aliwonse azachipatala omwe ndingaganizire?

Chidule ndi Uthenga Wopita Nawo Kunyumba

Matenda a Clear Cell Sarcoma ndi matenda ovuta kwambiri. Ndi osowa kwambiri. Amakhudza anthu ochepa okha pachaka. Ndipo amakula pang'onopang'ono kwambiri. Matenda a sarcoma amatha kufalikira ndikupha anthu ambiri akamaona kusintha kwa matupi awo.

Koma kumbukirani kuti madokotala amatha kuchiza clear cell sarcoma. Angathe kuchotsa chotupacho ndi opaleshoni, ndipo angakupatseninso chithandizo chophera maselo ena onse a khansa. Tsoka ilo, clear cell sarcoma nthawi zambiri imatha kubweranso. Chifukwa chake ndikofunikira kupita kukayezetsa nthawi zonse ndikuzindikira kusintha kulikonse m'thupi lanu.

Ofufuza zachipatala akufunafuna njira zatsopano zochizira matenda a clear cell sarcoma. Ngati muli ndi clear cell sarcoma, pali mayeso atsopano azachipatala.Ngati mukufuna kudziwa zambiri za izi, funsani dokotala wanu za izi ndipo pemphani upangiri. Musataye mtima. Ndi upangiri ndi chithandizo choyenera chachipatala, mutha kukumana ndi vutoli.

` clear cell sarcoma, khansa ya minofu yofewa, zotupa za miyendo, zotupa za miyendo, sarcoma, zizindikiro za khansa, chithandizo cha khansa