Kodi pituitary gland yanu "ilibe kanthu"? Tiyeni tiphunzire za Empty Sella Syndrome (ESS)!

Kodi nthawi zina mutu umapweteka nthawi zonse? Kapena mukuganiza kuti ndi chifukwa cha mahomoni? Ngati dokotala akunena kuti akufunika kujambulidwa mutu wanu ndi ``(CT)`` kapena ``(MRI)```, angapeze kuti dera lomwe pituitary gland yanu ili likuwoneka "lopanda kanthu." Ndicho chimene timachitcha Empty Sell. Koma kodi nthawi zonse ndi vuto lalikulu? Tiyeni tikambirane za izi mwatsatanetsatane.

Kodi Empty Sella Syndrome (ESS) ndi chiyani?

Mwachidule, Empty Sella Syndrome (ESS) ndi vuto losowa kwambiri. Limachitika pamene pituitary gland yanu - gland yaying'ono koma yofunika kwambiri yomwe ili pansi pa ubongo wanu - imaphwanyika kapena kufooka m'malo mwake, malo obisika a mafupa otchedwa sella turcica . Taganizirani izi, sella turcica ili ngati nyumba yaying'ono yomwe imateteza pituitary gland. Pazifukwa zina, 'nyumba' iyi ikhoza kukhala yayikulu kwambiri, zomwe zimapangitsa pituitary gland kutukumuka ndikuchepa.

Mawu akuti 'sella turcica' amachokera ku Chilatini, kutanthauza 'mpando waku Turkey'. Dzina lake limatchedwa choncho chifukwa limafanana ndi chishalo cha kavalo. Anthu ena omwe ali ndi ESS amatha kukhala ndi zizindikiro monga kusalinganika kwa mahomoni , mutu wopweteka pafupipafupi, komanso kusintha kwa masomphenya .

Kodi mukudziwa kuti pituitary gland ndi gawo lofunika kwambiri la dongosolo lathu la endocrine , lomwe ndi dongosolo lopanga mahomoni. Limapanga mahomoni ambiri ofunikira m'thupi lathu. Ma mahomoni awa amalamulira ma gland ena m'thupi lathu.

Kodi pali kusiyana kotani pakati pa Empty Sella ndi Empty Sella Syndrome?

Izi zikusokoneza pang'ono, choncho mvetserani mosamala. Ngakhale kuti mawu akuti 'selo lopanda kanthu' ndi 'selo lopanda kanthu' nthawi zina amagwiritsidwa ntchito mosiyanasiyana, pali kusiyana pang'ono. Mwachidule, selo lopanda kanthu ndi kupeza kwa radiological , pomwe vuto la selo lopanda kanthu ndi vuto lachipatala.

'Empty Sella' ndi pamene pituitary gland yanu imawoneka yopyapyala kapena yofooka pa scan. Pankhaniyi, madokotala sangathe kuwona pituitary gland bwino pa scan. Chifukwa chake, malo omwe pituitary gland ili, yotchedwa sella turcica, amaoneka 'opanda kanthu'. Apa ndi pomwe dzina lakuti 'empty sella' limachokera.

Komabe, sella turcica siili ndi kanthu kwenikweni. Nthawi zambiri, imadzazidwa ndi madzi a m'mitsempha (CSF) . CSF iyi ndi madzi omwe amazungulira ndikuteteza ubongo wathu ndi msana. Mu vuto la 'sella lopanda kanthu', madzi a CSF awa amalowa mu sella turcica ndikuyika mphamvu pa pituitary gland. Kupanikizika kumeneko kumapangitsa kuti gland ichepe kapena kuphwanyika.

Nthawi zambiri, madokotala amapeza 'selo lopanda kanthu' mwangozi. Izi zikutanthauza kuti, akamajambula ``(CT)`` kapena ``(MRI)``` pazifukwa zina.

Ngakhale kuti anthu ena ali ndi 'maselo opanda kanthu' pa ma scan awo, sangakhale ndi zizindikiro zilizonse ndipo pituitary gland yawo imatha kugwira ntchito bwino.

Komabe, ngati wina ali ndi 'empty sella' ndipo pituitary gland yake sikugwira ntchito bwino, ndicho chomwe timachitcha Empty Sella Syndrome (ESS) . Matendawa ndi mndandanda wa zizindikiro zofanana. Anthu omwe ali ndi ESS amatha kukumana ndi zinthu monga kusalinganika kwa mahomoni, kusintha kwa masomphenya, komanso mutu wopweteka pafupipafupi.

Pali mitundu iwiri ya Empty Sella, sichoncho?

Inde, pamene scan yanu yapeza 'selo lopanda kanthu', madokotala amaigawa m'magulu awiri: yoyamba ndi yachiwiri.

• Primary Empty Sella (PES): Apa ndi pamene madokotala sangapeze chifukwa chomveka bwino chomwe chimapangitsa kuti pituitary gland yanu iphwanyike. Nthawi zambiri, primary empty sella siyambitsa empty sella syndrome. Izi zikutanthauza kuti nthawi zambiri sizimayambitsa zizindikiro.
• Kugulitsa Kwachiwiri Kopanda Thupi (SES): Izi zimachitika chifukwa cha vuto lina lodziwika lomwe limakhudza kapangidwe ka pituitary gland yanu kapena sella turcica. Mwachidule, zimachitika chifukwa cha kuwonongeka kwa matenda ena kapena chochitika china. Pankhani ya secondary empty sella (SES), empty sella syndrome imayamba kwambiri kuposa pa nkhani ya primary empty sella (PES).

Kodi Empty Sella Syndrome (ESS) iyi ndi yoopsa kwa moyo?

Ayi, Empty Sella Syndrome (ESS) si vuto lomwe lingayambitse imfa. Lingathe kuchiritsidwa ndi mankhwala a mahomoni komanso nthawi zina opaleshoni.

Komanso, kungoti kusanthula ubongo wanu kumati 'selo lopanda kanthu' sikutanthauza kuti ndi chiopsezo ku moyo. Nthawi zambiri 'selo lopanda kanthu', palibe zizindikiro kapena vuto la maselo opanda kanthu.

Kodi ntchito ya Pituitary Gland ndi yotani?

Chiwalo cha pituitary ndi chinthu chofunikira kwambiri m'thupi lathu. Chimapanga mahomoni osiyanasiyana. Chimauzanso ma gland ena m'thupi lathu kuti atulutse mahomoni. Izi ndi izi:

• Matenda a adrenal
• Mazira (mwa akazi) kapena machende (mwa amuna)
• Chithokomiro cha chithokomiro

Mahomoni ali ngati amithenga a mankhwala. Amayenda m'magazi ndipo amatumiza mauthenga ku ziwalo zathu, minofu, ndi minofu ina. Mauthenga awa amauza thupi zomwe liyenera kuchita komanso nthawi yoti lichite.

Chiwalo cha pituitary chimalumikizidwa ndi hypothalamus muubongo wathu.Imalumikizidwa ndi phesi lopangidwa ndi mitsempha yamagazi ndi mitsempha. Imeneyi imatchedwa phesi la pituitary. Ndi kudzera mu phesi ili momwe hypothalamus imalankhula ndi pituitary gland ndikunena kuti, 'Chabwino, tsopano tulutsani mahomoni awa.' Hypothalamus ndi gawo la ubongo wathu lomwe limayang'anira zinthu monga kuthamanga kwa magazi, kugunda kwa mtima, kutentha kwa thupi, ndi kugaya chakudya.

Chiwalo cha pituitary chimapanga mahomoni otsatirawa:

• Homoni ya Adrenocorticotropic (ACTH): Izi zimalimbikitsa ma adrenal glands kupanga mahomoni (monga cortisol) omwe amayankha kupsinjika.
• Homoni yoletsa diuretic (ADH kapena vasopressin): Imalamulira bwino madzi m'thupi.
• Homoni yolimbikitsa follicle (FSH): Imathandiza mazira okhwima mwa akazi ndikupanga umuna mwa amuna.
• Homoni ya kukula (GH): Imathandiza matupi athu kukula kuyambira ali ana mpaka akuluakulu, makamaka m'mafupa ndi minofu.
• Homoni ya Luteinizing (LH): Imagwira ntchito ndi FSH kuti ithandize njira zoberekera kugwira ntchito. Ndi yofunika kwambiri pa ovulation mwa akazi komanso pakupanga testosterone mwa amuna.
• Oxytocin: Imathandiza kuti chiberekero chizigwira ntchito panthawi yobereka komanso kuti mkaka utsike panthawi yoyamwitsa.
• Prolactin: Imalimbikitsa kupanga mkaka wa m'mawere.
• Homoni yolimbikitsa chithokomiro (TSH): Imauza chithokomiro chomwe chili pakhosi kuti chipange mahomoni a chithokomiro. Mahomoni a chithokomiro awa amalamulira liwiro lomwe thupi lathu limagwiritsa ntchito mphamvu (kagayidwe kachakudya).

Si mahomoni onsewa omwe amapangidwa nthawi zonse. Ambiri amatulutsidwa nthawi imodzi, pafupifupi ola limodzi kapena atatu aliwonse.

Ndani amene amakhudzidwa kwambiri ndi Empty Sella Syndrome (ESS)?

Ngakhale kuti vutoli ndi losowa, ana ndi akuluakulu onse amatha kukhala ndi vuto la empty sella syndrome (ESS).

Komabe, selo lopanda kanthu (PES) - lomwe limangowoneka pa scan popanda zizindikiro zilizonse - ndi lofala kwambiri mwa akazi kuwirikiza kanayi kuposa amuna.

PES imapezeka kwambiri mwa anthu azaka zapakati pa 30 ndi 40. Nthawi zina imatha kuchitika msanga mwa akazi kuposa amuna. Akazi omwe atenga mimba nthawi yonse amakhala pachiwopsezo chachikulu chotenga PES.

PES si yofala kwambiri mwa ana kuposa akuluakulu. Ikachitika, nthawi zambiri imagwirizanitsidwa ndi matenda ena, monga Turner syndrome, matenda a Moyamoya, ndi Prader-Willi syndrome.

Kodi izi ndizofala bwanji?

Matenda a Empty Sella Syndrome (ESS) ndi osowa kwambiri. Ofufuza ena akuti anthu osakwana 1% omwe ali ndi 'empty sella' amakhala ndi zizindikiro (monga matenda a ESS).

Komabe, kukhala ndi sella yopanda zizindikiro n'kofala kwambiri. Malipoti ena akusonyeza kuti pakati pa 8% ndi 35% ya anthu akhoza kukhala ndi sella yopanda kanthu. Malipoti ena akusonyeza kuti pafupifupi 12% ya anthu ali ndi sella yopanda kanthu, kutengera zotsatira za scan ya ubongo.

Kodi zizindikiro za Empty Sella Syndrome (ESS) ndi ziti?

Chizindikiro chachikulu chokhudzana ndi empty sella syndrome (ESS) ndi mutu wosatha. Komabe, ofufuza sakudziwabe ngati mutu umenewu umayamba chifukwa cha ESS kapena ngati ndi mwangozi chabe. Izi zili choncho chifukwa anthu ambiri omwe ali ndi ESS alinso ndi kuthamanga kwa magazi (hypertension), komwe kungayambitsenso mutu ngati ukukulirakulira.

Nthawi zambiri ESS imayambitsa kusalingana kwa mahomoni chifukwa cha kuwonongeka kwa pituitary gland. Anthu omwe ali ndi ESS amatha kukhala ndi zizindikiro zosiyanasiyana kutengera kuwonongeka kwa pituitary gland yawo komanso mahomoni omwe amakhudzidwa. Ngati muli ndi ESS, mutha kukhala ndi zizindikiro izi:

• Kutuluka kwa mabere osatulutsa mkaka (galactorrhea) (izi zingachitikenso kwa amuna)
• Kulephera kwa erectile ( kwa amuna)
• Kusasamba kosakhazikika kapena kusasamba konse (amenorrhea) (kwa akazi)
• Kuchepa kapena kutayika kwa chilakolako chogonana (kuchepa kwa chilakolako chogonana)
• Kumva kutopa nthawi zonse (Kutopa)

Kawirikawiri, anthu ena omwe ali ndi ESS amathanso kuona zizindikiro monga:

• Kupanikizika kowonjezereka mkati mwa chigaza (kupanikizika koipa mkati mwa mutu)
• Matenda a Cerebrospinal rhinorrhea (CSF kutuluka m'mphuno)
• Kutupa kwa diski ya optic mkati mwa diso (papilledema) chifukwa cha kupanikizika kwakukulu m'chigaza
• Kusintha kwa masomphenya, mwachitsanzo, kusawona bwino.

Apanso, mutha kukhala ndi 'selo lopanda kanthu' pa scan ya ubongo, koma mwina simungakhale ndi zizindikiro zilizonse. Ndipotu, anthu ambiri omwe ali ndi 'maselo opanda kanthu' alibe zizindikiro zilizonse ndipo sadzakhala ndi zizindikiro.

Kodi Empty Sella Syndrome (ESS) imayambitsa kunenepa?

Ngati pituitary gland yanu siimapanga mahomoni okwanira olimbikitsa chithokomiro (TSH) chifukwa cha empty sella syndrome (ESS), pali mwayi woti mudzanenepa.

TSH imalimbikitsa chithokomiro, chomwe chili kutsogolo kwa khosi lanu, pansi pa khungu, kuti chitulutse mahomoni a chithokomiro. Ntchito yayikulu ya chithokomiro ndikupanga mahomoni a chithokomiro, omwe amayang'anira liwiro lomwe mumasinthira chakudya chomwe mumadya kukhala mphamvu, kapena liwiro lanu la kagayidwe kachakudya .

Ngati pituitary gland yanu siimapanga TSH yokwanira chifukwa cha ESS, chithokomiro chanu sichingapange mahomoni okwanira a chithokomiro. Izi zingayambitse kuchepa kwa kagayidwe kachakudya chifukwa cha kuchepa kwa mahomoni a chithokomiro, zomwe zingayambitse kunenepa.

Kodi n’chiyani chimayambitsa Empty Sella Syndrome (ESS)?

Matenda a Empty Sella (ESS) angayambitsidwe ndi primary empty sella (PES) kapena secondary empty sella (SES). Komabe, secondary empty sella (SES) ndi yomwe imayambitsa ESS.

Zomwe Zimayambitsa Matenda Opanda Thanzi a Sella (PES)

Matenda oyamba a m'mimba otchedwa primary esophagitis (PES) amapezeka pamene nembanemba imodzi yomwe imaphimba kunja kwa ubongo wanu (arachnoid layer), sella turcica, imatupa mkati, ndikukankhira pituitary gland.

Madokotala sanathebe kudziwa chomwe chimayambitsa vuto la primary empty sella syndrome.

Lingaliro limodzi ndi lakuti kufooka kobadwa nako m'minofu yophimba ubongo kumalola madzi a m'mitsempha ya ubongo (CSF) kulowa mu sella turcica, zomwe zimapangitsa kuti pituitary gland ikhale yopyapyala. M'mikhalidwe yotereyi, pituitary gland nthawi zambiri imakhala yovuta kuiona pa scan, koma nthawi zambiri imagwira ntchito bwino, kotero empty sella syndrome siimachitika.

Zomwe Zimayambitsa Kulephera Kugonana Kwachiwiri (SES)

Sella yachiwiri yopanda kanthu (SES) imachitika pamene pituitary gland yanu kapena sella turcica yawonongeka ndi matenda ena kapena chochitika china. Chifukwa chake, pali zifukwa zambiri zomwe zingayambitse SES. Kawirikawiri, zifukwa zazikulu za kuwonongeka kumeneku ndi izi:

• Chotupa cha muubongo.
• Chithandizo cha radiation .
• Opaleshoni ya ubongo yomwe inachitika m'dera lozungulira pituitary gland.
• Kuvulala mutu kwambiri, mwachitsanzo kuvulala koopsa muubongo.

Nazi zifukwa zina zomwe zingakhudze kutuluka kwa chikhodzodzo kachiwiri:

• Zotupa za muubongo: Nthawi zina zotupa za muubongo zimatha kuyambitsa kupanikizika kozungulira ubongo wanu (kupanikizika kwa mkati mwa ubongo), komwe kumatha kukanikiza pituitary gland.
• Kuthamanga kwa magazi m'mutu mwa munthu (IIH): IIH ndi kuwonjezeka kwa kuthamanga kwa magazi m'chigaza chifukwa cha kuchuluka kwa madzi m'mitsempha ya ubongo (CSF) kuzungulira ubongo wanu. Kupanikizika kochulukirapo kumeneku kumatha kufinya pituitary gland.
• Matenda a pituitary adenomas: Izi ndi zotupa zomwe zimayamba mu pituitary gland. Nthawi zambiri, sizimayambitsa khansa (zoipa). Matendawa amatha kukakamiza pituitary gland ndikuiwononga.
• Matenda a Sheehan: Uwu ndi matenda omwe nthawi zina amatha kuchitika ngati magazi ambiri akutuluka pathupi panthawi yobereka. Izi zingapangitse thupi kusowa mpweya ndikuwononga pituitary gland.

Kodi Empty Sella Syndrome (ESS) imapezeka bwanji?

Nthawi zambiri, madokotala amapeza sella yopanda kanthu mwangozi, akamayesa mutu pazifukwa zina. Komanso, anthu ambiri omwe ali ndi sella yopanda kanthu samakhala ndi empty sella syndrome kapena kukumana ndi zizindikiro zilizonse.

Komabe, ngati muli ndi zizindikiro zokhudzana ndi empty cell syndrome, monga mutu wopweteka pafupipafupi komanso kusakhazikika kwa mahomoni, dokotala wanu adzakufunsani za mbiri yanu yachipatala, adzakuyesani thupi, ndipo mwina adzakulamulani kuti mufufuze mutu ndi ubongo.

Ma scan omwe amagwiritsidwa ntchito pozindikira ESS ndi awa:

• Kujambula kwa ubongo (CT scan): Kujambula kwa ubongo (CT scan) ndi njira yojambulira zithunzi zomveka bwino za ubongo wanu ndi pituitary gland pogwiritsa ntchito X-ray ndi kompyuta.
• Kujambula ubongo pogwiritsa ntchito maginito: Kujambula ubongo pogwiritsa ntchito mafunde a wailesi ndi maginito amphamvu kuti apange zithunzi zomveka bwino za ziwalo zomwe zili mkati mwa thupi lanu, monga sella turcica yanu.

Dokotala wanu angafunenso kuyitanitsa mayeso ena, monga kuyezetsa magazi, kuti aone kuchuluka kwa mahomoni anu.

Nthawi zina, madokotala angachitenso mayeso ngati awa kuti awone ngati pali kuthamanga kwa magazi muubongo wanu:

• Uzani dokotala wa maso kuti aone retina yomwe ili mkati mwa diso lanu.
• Kuboola kwa msana (kupopera msana) - Izi zimayesa kuthamanga kwa madzi a msana.

Kodi mankhwala a Empty Sella Syndrome (ESS) ndi ati?

Ngakhale kuti ma scan anu akuwonetsa 'selo lopanda kanthu', ngati pituitary gland yanu ikugwira ntchito bwino, simudzafunika chithandizo chilichonse. Izi ndi zomwe zimachitika nthawi zambiri.

Komabe, ngati muli ndi Empty Sella Syndrome (ESS) ndipo pituitary gland yanu sikugwira ntchito bwino, chithandizocho ndi mankhwala okonza kuchuluka kwa mahomoni ochepa. Izi zikutanthauza kuti, mankhwalawo amatsimikiziridwa kutengera ndi mahomoni otsika.

Ngati ESS imayambitsa kutuluka kwa madzi m'mphuno mwanu (CSF rhinorrhea), mungafunike opaleshoni kuti mukonze sella turcica yanu.

Kodi ndi zinthu ziti zomwe zimayambitsa Empty Sella Syndrome (ESS)?

Madokotala sakudziwa bwino chomwe chimayambitsa empty sella syndrome mwa anthu ena omwe ali ndi empty sella. Komabe, empty sella syndrome imayamba chifukwa cha secondary empty sella (SES) kuposa primary empty sella (PES). Izi zikutanthauza kuti ngati empty sella imayamba chifukwa cha china chake, monga chotupa cha muubongo, radiation therapy, kapena kuvulala mutu, mumakhala ndi zizindikiro zambiri.

Kodi chiyembekezo cha munthu amene ali ndi Empty Sella Syndrome (ESS) ndi chotani?

Chiyembekezo cha munthu amene ali ndi vuto la empty sella syndrome (ESS) nthawi zambiri chimakhala chabwino. Pali mankhwala ochizira kusalinganika kwa mahomoni. Ngati muli ndi kusalinganika kwa mahomoni chifukwa cha ESS, mungafunike kumwa mankhwala moyo wanu wonse.

Kodi muyenera kupita kwa dokotala liti ngati muli ndi vuto la maselo opanda kanthu?

Ngati mwapezeka ndi Empty Sella Syndrome (ESS), ndipo mukuyamba kukhala ndi zizindikiro zatsopano kapena ngati zizindikiro zomwe muli nazo zikuipiraipira, pitani kwa dokotala nthawi yomweyo.

Ngati mukumwa mankhwala a kusalinganika kwa mahomoni chifukwa cha vuto la m'mimba wopanda kanthu, ndikofunikira kwambiri kukaonana ndi dokotala nthawi zonse kuti muwonetsetse kuti mankhwala anu akugwira ntchito bwino.

Ndiye, kodi tiyenera kukumbukira chiyani kuchokera pa izi?

Eya, Empty Sella Syndrome (ESS) ndi vuto losowa kwambiri. Komabe, nthawi zambiri mumapeza kuti muli ndi chinthu chotchedwa 'selo lopanda kanthu' pa scan ya ubongo. Choncho musachite mantha chifukwa dokotala wakuuzani zimenezo. Nthawi zambiri, anthu omwe ali ndi 'selo lopanda kanthu' sakhala ndi zizindikiro zilizonse ndipo sakhala ndi Empty Sella Syndrome.

Ngati muli ndi mafunso okhudza lipoti lanu la scan, musaope kufunsa dokotala wanu. Iwo alipo kuti akuthandizeni. Kusamalira thanzi lanu ndiye chinthu chofunikira kwambiri.

Matenda a Empty Sella, Pituitary gland, Mahomoni, Kujambula ubongo, Sellae Tursica