Mwina mwawonanso nkhani yaposachedwa yokhudza Human Growth Hormone, kapena HGH. Kumva kuti homoni iyi ingayambitse matenda a Alzheimer's kuyenera kuti kunakuchititsani mantha komanso kuda nkhawa pang'ono, sichoncho? Mantha awa akhoza kukhala akulu kwambiri ngati dokotala wakupatsani chithandizo cha homoni iyi kwa inu kapena mwana wanu. Tiyeni tikambirane mwatsatanetsatane lero, zoona zake n'ziti m'nkhaniyi, ndipo timvetsetse bwino ngati tiyenera kuopa kapena ayi.
Kodi nkhaniyi inayamba bwanji?
Nkhaniyi mwadzidzidzi inachokera ku kafukufuku wochitidwa ndi gulu la ofufuza ku Britain mu chaka cha 2024. Anapeza kuti kalekale, pakati pa 1959 ndi 1989, anthu angapo omwe adalandira mtundu wapadera wa HGH woperekedwa kwa ana okhwima pambuyo pake adayamba matenda a Alzheimer's.
Koma chofunika kwambiri apa ndi mtundu wa HGH womwe unkagwiritsidwa ntchito panthawiyo. Umatchedwa cadaveric growth hormone . Mwachidule, mahomoni amenewo ankatengedwa kuchokera m'matupi a anthu akufa, makamaka kuchokera ku pituitary gland muubongo. Taganizirani izi, zili ngati kuchiza munthu wina ndi gawo la thupi lake.
Cha m'ma 1985, munthu amene anamwa mahomoni akale amenewa anayamba matenda oopsa a muubongo otchedwa Creutzfeldt-Jakob disease (CJD) . Ndi matenda omwe amachititsa kuti munthu aiwale zinthu mofanana ndi matenda a Alzheimer's. Mayeso a pambuyo pake adatsimikizira kuti matenda a CJD amenewa adayambitsidwa ndi vuto la mahomoni omwe adatengedwa kwa anthu omwe anamwalira. Ndi izi, HGH kuchokera kwa anthu omwe anamwalira idathetsedwa kwathunthu padziko lonse lapansi.
Kafukufuku watsopano posachedwapa adapeza kuti pamene ubongo wa anthu angapo omwe adamwalira ndi CJD unafufuzidwa, unali ndi mapuloteni otchedwa beta-amyloid mu ubongo wawo. Uwu ndi mapuloteni omwewo omwe amasungidwa mu ubongo wa anthu omwe ali ndi matenda a Alzheimer. Ambiri mwa anthuwa adakhala ndi zizindikiro za matenda a Alzheimer ali aang'ono kwambiri, ali ndi zaka za m'ma 30 ndi 40.
Choncho kafukufukuyu akusonyeza kuti kuipitsidwa kwina kwa HGH yakale, yomwe yakhalapo kwa zaka makumi ambiri, yomwe inatengedwa kuchokera kwa anthu omwe anamwalira, mwina kunapangitsa kuti mapuloteni okhudzana ndi matenda a Alzheimer alowe m'thupi.
Ndiye kodi HGH yoperekedwa lero ndi yoopsa?
Nayi mfundo yofunika kwambiri yomwe muyenera kumvetsetsa bwino. Ayi. HGH yomwe yaperekedwa lero si yoopsa kwenikweni.
Kwa zaka zambiri, madokotala padziko lonse lapansi akhala akupereka mankhwala a HGH opangidwa . Ndiko kuti, mahomoni omwe amapangidwa mu labotale mwanjira yoyera kwambiri, yotetezeka, komanso yopangidwa. Alibe minofu ya munthu. Chifukwa chake, palibe mwayi woti CJD, kapena puloteni ya Alzheimer, monga momwe kafukufuku wakale akusonyezera, imatha kupatsirana kuchokera kwa munthu wina kupita kwa wina.
Tiyeni tiwone bwino kusiyana pakati pa njira ziwirizi.
| Khalidwe | HGH yakale (Cadaveric - isanafike 1989) | HGH Yamakono (Yopangidwa - Yamakono) |
|---|---|---|
| Momwe mungapezere | Zochokera ku glands ya pituitary ya anthu omwe anamwalira. | Yopangidwa mwaluso komanso mwaukhondo mu labotale. |
| Chitetezo ndi chiopsezo | Panali chiopsezo chofalitsa mapuloteni okhudzana ndi matenda monga CJD ndi Alzheimer's. | Popeza mulibe minofu ya munthu , palibe chiopsezo chotenga kachilomboka. |
| Kagwiritsidwe ntchito pano | Sichikugwiritsidwa ntchito kulikonse padziko lapansi kwa zaka makumi ambiri tsopano. | Uwu ndi mtundu wokhawo wa HGH womwe umagwiritsidwa ntchito polemba mankhwala. |
Tiyeni tiphunzirenso za kusintha kwachilengedwe kwa milingo ya HGH.
Pali maphunziro omwe akusonyeza kuti kuchuluka kwa HGH m'thupi (monga matenda monga acromegaly ) kapena kuchepa kwa HGH kungakhale ndi zotsatirapo zina pa kukumbukira mtsogolo. Koma zimenezo n'zosiyana kwambiri ndi kumwa HGH mu mlingo woyenera ngati chithandizo motsogozedwa ndi dokotala. Ndipotu, ngati munthu amene ali ndi vuto la HGH sanalandire chithandizo choyenera, ubongo wake ukhoza kuchepa.
Kodi matenda a Alzheimer ndi opatsirana?
Izi ndi vuto kwa anthu ambiri. Ayi. Matenda a Alzheimer si opatsirana. Simungatenge matendawa chifukwa choti munasamalira munthu amene ali ndi matenda a Alzheimer, munali naye, munagwiritsa ntchito chinthu chomwe iwo anagwiritsa ntchito. Si opatsirana ngati chimfine.
Chomwe chinachitika pa chochitika chakale cha HGH chinali kubayidwa kwa zinthu zamoyo zomwe zaipitsidwa m'thupi. Zimenezo ndi zapadera kwambiri ndipo sizichitikanso.
Zinthu zenizeni zomwe zimayambitsa matenda a Alzheimer's ndi izi:
- Kukalamba: Chiwopsezo chimawonjezeka ndi ukalamba.
- Mbiri ya banja: Chiopsezo chimakhala chachikulu ngati wina m'banjamo adadwalapo.
- Kuvulala kwambiri kumutu.
- Matenda ena: kuthamanga kwa magazi, matenda a shuga, cholesterol yambiri.
- Moyo: Kudya zakudya zosapatsa thanzi, kunenepa kwambiri, kusachita masewera olimbitsa thupi, komanso kusagona mokwanira.
Ndiye kodi ndiyenera kusiya chithandizo cha HGH?
Ayi, ayi ndithu. Ngati inu kapena mwana wanu mukulandira chithandizo cha HGH motsatira malangizo a dokotala, musachite mantha ndipo siyani chithandizo nthawi yomweyo mutangomva nkhani ngati iyi. Kuchita zimenezi kumabweretsa mavuto ambiri kuposa zabwino.
Masiku ano, chithandizo cha HGH chimaperekedwa pazifukwa zomveka bwino zachipatala. Mwachitsanzo:
- Kusowa kwa mahomoni okula
- Kuchepa kwa thupi komwe kumachitika chifukwa cha majini monga Turner syndrome ndi Prader-Willi syndrome .
- Kutaya minofu chifukwa cha kachilombo ka HIV.
- Matenda a m'mimba afupiafupi.
Chithandizo cha HGH ndi chithandizo chofunikira kwambiri komanso chotetezeka kwa anthu omwe ali ndi matenda awa. Chifukwa chake, chinthu chabwino kwambiri chomwe mungachite ndikukambirana momasuka kukayikira kapena mantha aliwonse omwe muli nawo ndi dokotala wanu. Iye adzakufotokozerani izi mwatsatanetsatane ndikuchepetsa mantha anu.
Ngati inu kapena mwana wanu mwapatsidwa chithandizo cha HGH ndi dokotala, onetsetsani kuti mwalankhulana naye musanasiye. HGH yopangidwa yomwe ikugwiritsidwa ntchito pakadali pano siyikuika pachiwopsezo cha matenda a Alzheimer's.
Uthenga Wopita Nawo Kunyumba
- Posachedwapa, pakhala nkhani yokhudza mtundu wa HGH wochokera kwa anthu omwe anamwalira womwe unagwiritsidwa ntchito zaka makumi angapo zapitazo (1959-1989). Sagwiritsidwanso ntchito kulikonse.
- HGH yomwe imagwiritsidwa ntchito masiku ano ndi homoni yotetezeka kwambiri yopangidwa mu labotale (yopangidwa). Siili ndi chiopsezo chofalitsa matenda monga Alzheimer's kapena CJD.
- Matenda a Alzheimer si matenda omwe amafalikira kuchokera kwa munthu kupita kwa munthu m'moyo watsiku ndi tsiku.
- Ngati dokotala wanu wakulangizani kuti mulandire chithandizo cha HGH, pitirizani popanda mantha. Ngati mukukayikira, onetsetsani kuti mwalankhula ndi dokotala wanu musanasiye kulandira chithandizo.
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