Katemera watsopano wa cholesterol yambiri (Hyperlipidemia)? Tiyeni tiphunzire za Leqvio!

"Dokotala, papita nthawi kuchokera pamene ndinayamba kumwa mankhwala a cholesterol iyi. Ndimawongoleranso zakudya zanga bwino. Koma kuchuluka kwa cholesterol yanga sikunatsikebe..." Kodi inunso mumamva chonchi? Kapena wina m'banja mwanu ali ndi vutoli? Ndipotu, kulamulira cholesterol ndi vuto lalikulu kwa anthu ena. Ngakhale kuti anthu ambiri amapeza zotsatira zabwino kuchokera ku mankhwala a 'statin', ena sapeza. Chifukwa chake, mankhwala atsopano otchedwa Leqvio ayambitsidwa kuti athandize anthu otere. Tiyeni tikambirane za izi mwatsatanetsatane komanso lero.

Kodi cholesterol yokwera iyi (Hyperlipidemia) ndi chiyani?

Mwachidule, Hyperlipidemia ndi pamene muli ndi mitundu yambiri ya mafuta (timawatcha kuti lipids) m'magazi mwanu. Tonsefe timafunikira mafuta ena m'thupi mwathu. Amagwira ntchito zambiri zofunika. Koma akakwera kwambiri ndi pamene mavuto amayamba. Ngati mafuta awa achuluka pakapita nthawi, chiopsezo chotenga matenda aakulu monga matenda a mtima, sitiroko, ndi matenda a mtima chimawonjezeka kwambiri.

Nthawi zambiri timalankhula za mitundu iwiri ikuluikulu ya mafuta.

Kuphatikiza apo, pali mtundu wina wa mafuta wotchedwa triglycerides. Si bwino kukhala nawo ochulukirapo.

Kodi ndi zifukwa ziti zomwe zimapangitsa kuti cholesterol ikhale yokwera?

Nthawi zambiri, izi zimachitika chifukwa cha kuphatikiza kwa moyo wathu, zakudya, ndi matenda ena.

• Chakudya ndi Zakumwa: Nyama yofiira, masoseji, nyama yankhumba, ndi zakudya zokhala ndi mafuta ambiri (mpunga wokazinga, kebabs, parathas) zimakhala ndi mafuta ambiri okhuta. Kudya izi nthawi zambiri kumawonjezera cholesterol.
• Moyo:Zinthu monga kusuta fodya, kumwa mowa mopitirira muyeso, kupsinjika maganizo, komanso kusachita masewera olimbitsa thupi zimakhudza kwambiri kuchuluka kwa cholesterol m'thupi.
• Matenda ena: Matenda monga matenda a shuga, mavuto a chiwindi kapena impso, hypothyroidism, ndi sleep apnea angayambitsenso cholesterol yambiri.

Cholinga chachikulu cha chithandizo ndi kuchepetsa kuchuluka kwa mafuta "oipa" m'magazi. Izi zitha kuchepetsa chiopsezo cha zochitika zazikulu monga matenda a mtima ndi sitiroko.

Kodi mankhwala a Leqvio amagwira ntchito bwanji?

Ma statin ndi mankhwala akuluakulu a cholesterol. Komabe, anthu ena sapeza cholesterol yokwanira monga momwe angafunire ngakhale atamwa mankhwalawa komanso kutsatira zakudya zabwino. Anthu omwe ali ndi vuto la majini lotchedwa "primary hyperlipidemia" angafunike mankhwala angapo.

Leqvio ndi mankhwala atsopano omwe abwera kudzathandiza anthu awa. Chomwe chimagwira ntchito mkati mwake ndi Inclisiran. Ndi cha gulu la mankhwala otchedwa `small interferencing RNA (siRNA)`.

Iyi ndi njira yosiyana kwambiri ndi momwe mankhwala a statin amagwirira ntchito.

Kodi pali aliyense amene ali ndi cholesterol yambiri amene angagwiritse ntchito Leqvio?

Ayi. Iyi si mankhwala a aliyense. Leqvio imavomerezedwa kwa anthu omwe ali kale ndi zakudya zopatsa thanzi komanso omwe amatenga mlingo waukulu wa statin, koma akadali ndi cholesterol yambiri .

Mankhwalawa angakulimbikitseni, makamaka kwa anthu omwe ali ndi vuto la majini lotchedwa `Heterozygous Familyal Hypercholesterolemia (HeFH).` Ngati muli ndi cholesterol yambiri ndipo milingo yanu siikutsika ngakhale mutamwa ma statins komanso mukudya zakudya zabwino, dokotala wanu angakuuzeni za Leqvio. Dokotala wanu yekha ndi amene angasankhe ngati izi ndi zoyenera kwa inu.

Kodi ndingapeze bwanji katemera uyu?

Leqvio si piritsi, ndi jakisoni . Ndi jakisoni wopangidwa pansi pa khungu. Simungaperekedwe kunyumba. Amaperekedwa ndi katswiri wa zaumoyo (dokotala kapena namwino) kuchipatala kapena kuchipatala.

Ndondomeko ya katemera ndi iyi:

1. Katemera woyamba: Mudzapatsidwa katemera kamodzi kaye.

2. Katemera wachiwiri:Katemera wachiwiri amaperekedwa miyezi itatu pambuyo pa woyamba.

3. Pambuyo pake: Pambuyo pake, muyenera kulandira jakisoni kamodzi miyezi 6 iliyonse .

Katemerayu akhoza kubayidwa m'ntchafu, m'mimba, kapena kumbuyo kwa mkono wapamwamba. Ndikofunikira kwambiri kupeza katemera wanu pa nthawi yake komanso kusaphonya nthawi iliyonse yokumana ndi dokotala.

Kodi mukudziwa chiyani za kupambana kwa Leqvio?

Kafukufuku wamkulu atatu achitika kuti aone momwe Leqvio ilili yothandiza komanso yotetezeka. Kafukufukuyu adachitika kwa miyezi 18.

• Maphunziro awiri: Ophunzirawo adaphatikizapo anthu omwe ali ndi matenda a mtima omwe sanathe kuchepetsa kuchuluka kwa cholesterol m'thupi lawo ngakhale adagwiritsa ntchito ma statins.
• Mu kafukufuku wina, ophunzirawo anali omwe anali ndi vuto la chibadwa la cholesterol lotchedwa `HeFH`.

Mu maphunzirowa, gulu limodzi linapatsidwa katemera wa Leqvio ndipo gulu lina linapatsidwa katemera wa placebo womwe sunathandize. Zotsatira zake zinali zomveka bwino.

Zotsatirazi zikusonyeza kuti Leqvio ndi mankhwala omwe angathe kuchepetsa kwambiri kuchuluka kwa cholesterol ya LDL yomwe siilamulidwa ndi ma statins. Nthawi zambiri kuchuluka kwa cholesterol kumayamba kuchepa mkati mwa miyezi itatu yoyambirira.

Kodi mankhwalawa amachepetsa chiopsezo cha matenda a mtima ndi sitiroko?

Funso ili ndi lofunika kwambiri. Mankhwala a statin awonetsedwa kuti amachepetsa cholesterol ya LDL ndikuchepetsa chiopsezo cha matenda a mtima ndi sitiroko. Koma Leqvio ndi mankhwala omwe amagwira ntchito mosiyana.

Komabe, kuchepa kwakukulu kwa cholesterol ya LDL kukusonyeza kuti chiopsezochi chikhoza kuchepetsedwa mtsogolo. Maphunziro ena a nthawi yayitali akupitilira kutsimikizira izi.

Zotsatirapo zake ndi momwe mungathanirane nazo?

Monga mankhwala ena aliwonse, Leqvio ingayambitse zotsatirapo zazing'ono. Zofala kwambiri ndi zomwe zimachitika pamalo omwe jakisoni amaperekedwa .

• Kufiira pamalo omwe adabayidwa jakisoni
• Kuyabwa
• Ululu

Pachifukwa ichi, katswiri wa zaumoyo amene akupereka katemera sadzapereka katemerayo pamalo omwe apsa ndi dzuwa, omwe ali ndi ziphuphu, kapena omwe ali ndi kachilomboka. Ngati mudalandirapo jakisoni kale ndipo mwakhala mukumva kupweteka kwambiri, uzani dokotala kapena namwino. Kenako angasankhe malo ena.

Kupatula izi, zotsatirapo zina zingachitike. Ngati mukukumana ndi zizindikiro zachilendo, lankhulani ndi dokotala nthawi yomweyo.

Pakadali pano palibe umboni woti pali kuyanjana pakati pa Leqvio ndi mankhwala ena. Komabe, ndikofunikira kuuza dokotala wanu za mankhwala onse, mavitamini, ndi mankhwala azitsamba omwe mukumwa.