Kodi muli ndi chotupa chosowa kwambiri m'mitsempha yanu? (Malignant Peripheral Nerve Sheath Tumor - MPNST) Tiyeni tiphunzire za icho.

Kodi munayamba mwamvapo chotupa kwinakwake pathupi lanu, mwina pa mkono kapena mwendo, chomwe chimakula pang'onopang'ono? Zotupa izi, zomwe nthawi zina zimayamba pang'ono ngati nandolo ndikukulira ngati lalanje, ndi zomwe tikambirane lero. Imeneyi ndi vuto lalikulu, koma losowa kwambiri. Limatchedwa chotupa cha mitsempha ya m'mphepete mwa mitsempha, kapena MPNST mwachidule.

Kodi chotupa cha mitsempha ya m'magazi (MPNST) n'chiyani?

Mwachidule, MPNST (Malignant Peripheral Nerve Sheath Tumor) ndi chotupa cha khansa chosowa kwambiri chomwe chimayamba m'maselo oteteza (mitsempha) yozungulira mitsempha m'thupi lanu. Izi ndi za mtundu wa sarcoma yofewa ya minofu . Zimatuluka m'thupi lanu la mitsempha . Taganizirani izi, mutha kupeza zotupa izi m'manja ndi miyendo yanu. Sikuti nthawi zina zimathanso kukula m'chiuno, m'mimba, pamutu, ndi pakhosi. Zotupa izi zimatha kuchiritsidwa pozichotsa opaleshoni. Komabe, tiyeneranso kukumbukira kuti nthawi zina zotupa izi zimatha kubwereranso .

Kodi MPNST ndi yosowa bwanji?

Imeneyi ndi vuto losowa kwambiri. Munthu m'modzi yekha pa anthu 100,000 ndi amene amapezeka ndi khansa ya m'magazi yotchedwa malignant peripheral nerve sheath (MPNST) chaka chilichonse. Nthawi zambiri imakhudza anthu azaka zapakati pa 30 ndi 50 .

Kuphatikiza apo, anthu omwe ali ndi vuto la majini lotchedwa Neurofibromatosis type 1 (NF1) ali ndi mwayi waukulu wopeza MPNST. Zapezeka kuti pakati pa 25% ndi 50% ya anthu omwe ali ndi MPNST alinso ndi NF1 .

Kawirikawiri, MPNST imatha kudwala msanga mwa anthu omwe ali ndi NF1 kuposa anthu omwe alibe NF1. Komanso, amuna omwe ali ndi NF1 ali ndi mwayi wodwala MPNST kuposa omwe alibe NF1.

Kodi zizindikiro za MPNST ndi ziti?

Ma MPNST amatha kufalikira kulikonse m'mitsempha yanu ya m'mphepete mwa thupi, koma nthawi zambiri amakhudza madera monga manja ndi miyendo yanu. Nthawi zina amathanso kufalikira m'malo monga m'chiuno, pachifuwa, pamimba, kapena pamutu ndi pakhosi. Zizindikiro za ma MPNST ndi izi:

• Chotupa chomwe chimakula pang'onopang'ono pansi pa khungu. Chotupachi chingakhale chaching'ono ngati nandolo (pafupifupi masentimita awiri) kapena chachikulu ngati lalanje (pafupifupi masentimita 10).
• Kumva kupweteka (makamaka ngati muli ndi NF1).
• Kusanza (Paresthesia).
• Kumva kufooka m'manja ndi miyendo.

Kodi zifukwa za MPNST ndi ziti?

Kafukufuku wasonyeza kuti 50% ya zotupa za m'mitsempha ya m'mphepete mwa mitsempha zimayambitsidwa ndi neurofibromatosis mtundu 1 (NF1).Mkhalidwewu umatchedwa. Zifukwa zina zingakhale:

• Chithandizo cha radiation: Pafupifupi 10% ya anthu omwe ali ndi MPNST adalandira chithandizo cha radiation cha matenda ena.
• Kusintha kwa majini: Ofufuza apeza kuti pali kusintha kwa majini kosiyanasiyana komwe kumayambitsa maselo abwinobwino a mitsempha kukhala maselo osazolowereka, kuchulukana, ndikupanga zotupa.
• Mitundu ina ya neurofibromas: Anthu omwe ali ndi plexiform neurofibroma ali pachiwopsezo chachikulu chotenga MPNST.

Kodi MPNST imapezedwa bwanji?

Mukapita kwa dokotala, choyamba adzakuyesani thupi lanu ndikufunsani za thanzi lanu. Izi zikuphatikizapo kufunsa za mbiri yanu yachipatala, mbiri yachipatala ya banja lanu, ndi zizindikiro zilizonse zomwe mungakhale nazo. Kuphatikiza apo, angachite izi:

• Mayeso ojambulira: Madokotala amatha kuchita mayeso monga MRI (Magnetic Resonance Imaging) ndi PET (Positron Emission Tomography) .
• Kufufuza za thupi: Dokotala angachite biopsy, kutenga chitsanzo cha minofu ndikuyiyesa pogwiritsa ntchito maikulosikopu ndi katswiri wa matenda .
• Mayeso a majini: Ngati muli ndi chotupa cha m'mitsempha yozungulira, dokotala wanu angakulangizeni kuti muyesedwe majini kuti muwone ngati inu kapena wachibale wanu ali ndi neurofibromatosis mtundu 1 (NF1) kapena mtundu wina wa chotupa cha m'mitsempha , neurofibromatosis mtundu 2 (Schwannomatosis) .

Kodi mankhwala a MPNST ndi ati?

Madokotala nthawi zambiri amachita opaleshoni kuti achotse chotupa cha m'mitsempha yoopsa. Komabe, pali zochitika zina pomwe opaleshoni siingatheke. Mwachitsanzo:

• Mtedza waukulu (mtedza wa 5 cm kapena kuposerapo).
• Matenda a Metastatic.
• Zotupa zomwe zili pafupi kwambiri ndi maukonde ovuta a mitsempha zimatha kuwonongeka panthawi ya opaleshoni.

Pazochitikazi, madokotala amatha kuchiza MPNST ndi kuphatikiza opaleshoni, chemotherapy , kapena chithandizo cha radiation . Chithandizo cha radiation chingaperekedwe opaleshoni isanachitike kapena itatha.

Ofufuza tsopano akufufuza ngati chithandizo cha immunotherapy kapena chithandizo cholunjika chingagwiritsidwe ntchito ngati mankhwala atsopano. Ngati muli ndi chotupa cha mitsempha yoipa, mutha kulandira mayeso azachipatala omwe amayesa mankhwala atsopano.Kungakhale bwino kukambirana ndi dokotala wanu za kutenga nawo mbali.

Kodi ndi mavuto ati omwe angakhalepo kapena zotsatirapo zake zomwe zingachitike chifukwa cha chithandizo?

Mavuto omwe angachitike panthawi ya opaleshoni ndi awa:

• Mayankho a mankhwala oletsa ululu.
• Kutuluka magazi kwambiri (kutuluka magazi).
• Ululu.
• Zipsera za opaleshoni.
• Matenda a bala ochitidwa opaleshoni.

Mankhwala monga chemotherapy kapena radiation therapy angayambitse zotsatirapo zoyipa monga:

• Kutsegula m'mimba.
• Kutopa.
• Kusanza ndi kusanza.

Kodi chiyembekezo cha munthu amene ali ndi MPNST ndi chiyani?

Kulosera za matenda ndi momwe gulu lanu lachipatala limaganizira kuti mudzakhala mutamaliza chithandizo. Pankhani ya MPNST, kulosera kumeneku kumatsimikiziridwa ndi zinthu zingapo:

• Mkhalidwe wa NF1: Pamene zotupazi zikukula mwa anthu omwe ali ndi NF1, chiyembekezo choti adzachira chingakhale chotsika pang'ono poyerekeza ndi anthu omwe alibe NF1.
• Kuchuluka kwa khansa: Akatswiri a matenda amaona maselowo pogwiritsa ntchito maikulosikopu ndipo amaika khansa m'magulu monga yapamwamba kapena yotsika . Zotupa zapamwamba zimakhala ndi mwayi waukulu wokhala ndi maselo a khansa omwe amagawikana mwachangu ndikufalikira.
• Kukula kwa chotupa: Zotupa za MPNST zimatha kukhala zazikulu mpaka masentimita 10. Zotupa zazikulu nthawi zambiri zimakhala zovuta kuzichotsa opaleshoni.
• Kufalikira kwa maselo m'thupi: Ngati chotupacho chafalikira kumadera ena kuchokera pamene chinayambira, chingakhale chovuta kuchichiza.

Monga mukuonera, pali zinthu zambiri zomwe zingakhudze mwayi wanu wochira, ndipo si zonse zomwe zingakukhudzeni. Chifukwa chake, ndi bwino kufunsa dokotala wanu kuti akuuzeni tsatanetsatane wa vuto lanu. Popeza akudziwa momwe zinthu zilili, akhoza kukupatsani chidziwitso chomwe mukufuna.

Kodi kuchuluka kwa moyo wa MPNST ndi kotani?

Kuchuluka kwa anthu omwe ali ndi matenda a mtima ndi kuyerekezera kwa anthu ena omwe adakumana ndi matenda a khansa. Chifukwa chakuti matendawa ndi osowa kwambiri, n'zovuta kwa akatswiri kupereka ziwerengero zenizeni. Malinga ndi National Cancer Institute (US), pakati pa 23% ndi 69% ya anthu omwe ali ndi MPNST amakhala ndi moyo zaka zisanu atapezeka ndi matendawa. Ndi kuchuluka kwakukulu, sichoncho? Chifukwa chake ndi bwino kufunsa dokotala wanu za vuto lanu.

Kodi ndimadzisamalira bwanji?

Ngati muli ndi chotupa cha m'mitsempha yoipa, mukukumana ndi khansa yosowa yomwe ingabwererenso mutalandira chithandizo. Pali mapulogalamu angapo omwe angakuthandizeni pankhaniyi:

• Chisamaliro cha kupweteka kwa mutu:Mu chisamaliro cha palliative, mudzagwira ntchito ndi gulu la madokotala ophunzitsidwa bwino omwe angakuthandizeni kuthana ndi zizindikiro za MPNST ndi zotsatirapo zake. Komanso, adzakupatsaninso chithandizo chamaganizo.
• Mapulogalamu opulumutsa khansa: Khansa ili ngati ulendo. Mapulogalamu opulumutsa khansa amakutsogolerani kuyambira tsiku lomwe mwapezeka ndi matendawa, kudzera mu chithandizo chanu, komanso zomwe mungachite ngati khansayo yabwerera.

Poyamba, chotupa cha m'mitsempha ya m'magazi (MPNST) chomwe chili m'dzanja kapena mwendo wanu chingawoneke ngati chotupa chomwe mungavulale kapena kuvulala mosavuta. Kudziwa kuti chotupacho ndi khansa yosowa kwambiri ndipo imafuna opaleshoni kungakhale kodabwitsa. Zingakhale zovuta kuzimvetsa. Ngati muli ndi mafunso okhudza matenda anu kapena zomwe mungayembekezere, gulu lanu lachipatala likumvetsa. Adzakhala okondwa kutenga nthawi yoyankha mafunso anu ndikuyankha nkhawa iliyonse yomwe mungakhale nayo.

Uthenga wochokera m'nkhaniyi wokhudza kupita kunyumba

Chabwino, ndikukhulupirira kuti mwamvetsa bwino za matenda a khansa osowa otchedwa MPNST omwe takambirana lero. Kumbukirani, awa ndi matenda osowa kwambiri. Ngati muli ndi zotupa zachilendo, ululu, dzanzi, ndi zina zotero m'thupi lanu zomwe zikupitirira, onani dokotala ndikupeza upangiri. Akapezeka msanga, zimakhala zosavuta kuchiza.

Chofunika kwambiri ndichakuti simuli nokha. Gulu lanu lachipatala, banja lanu, ndi anzanu onse alipo kuti akuthandizeni. Chofunika kwambiri ndikukhala olimba mtima ndikutsatira malangizo a dokotala wanu.

Chotupa cha m'chifuwa cha mitsempha yozungulira, MPNST, khansa ya mitsempha, chotupa, khansa, neurofibromatosis, NF1, opaleshoni, chithandizo cha radiation, chemotherapy