Kodi nthawi zambiri mumakhala ndi ziwengo ndi madontho ofiira komanso kuyabwa thupi lonse? Izi zitha kukhala Mastocytosis!

Kodi nthawi zambiri mumamva zotupa zofiira, zoyabwa, komanso nthawi zina zoopsa m'thupi lanu? Kapena mumavutika ndi vuto lalikulu la ziwengo ngakhale pang'ono kwambiri kwa masiku ambiri? Mungaganize kuti, "Ndili ndi vuto lina la ziwengo." Komabe, nthawi zina kumbuyo kwa zizindikirozi, pakhoza kukhala vuto losowa lomwe sitinamvepo. Limodzi mwa matenda amenewa ndi `(Mastocytosis)`. Ngakhale kuti dzinalo lingamveke lachilendo pang'ono, tiyeni tikambirane mwachidule.

Kodi Mastocytosis ndi chiyani? Mwachidule...

Tangoganizani, mkati mwa matupi athu muli maselo omwe ali ngati alonda ang'onoang'ono achitetezo. Timawatcha "mast cells." "Mast cells" awa ndi gawo la "chitetezo chathu chamthupi." Ali ngati asilikali achitetezo a dziko lathu. Adani monga majeremusi, mabakiteriya, ndi zinthu zina zomwe zimayambitsa ziwengo akalowa m'thupi, "mast cells" awa amabwera kudzamenyana.

Pamene `(mast cells)` awa ayankha kwa adani, amatulutsa mankhwala otchedwa `(histamine).` `(histamine)` iyi ndi yomwe imayambitsa zizindikiro za ziwengo m'thupi lathu (monga kuyabwa, kufiira kwa khungu, kutupa). `(mast cells)` awa amathandizanso kupanga asidi m'mimba.

Kawirikawiri, `(mast cells)` amenewa amagwira ntchito yawo ndikuwongolera adani kenako amakhala chete kachiwiri. Komabe, zomwe zimachitika m'thupi la munthu yemwe ali ndi `(Mastocytosis)` ndikuti `(mast cells)` awa amawonjezeka modabwitsa komanso mosalamulirika. Akawonjezeka chonchi, maselowa amatulutsa `(histamine) wochuluka kwambiri. Pamenepo ndi pamene mumakhala ndi allergy yayikulu ngakhale chinthu chaching'ono kwambiri, kapena mukadwala allergy, imakhala yoipa kuposa mwa munthu wabwinobwino, ndipo imakhala nthawi yayitali.

Chofunika kwambiri n'chakuti, aliyense amene ali ndi Mastocytosis ali pachiwopsezo chachikulu cha anaphylaxis , zomwe zimayambitsa mwadzidzidzi, zoopsa, komanso zomwe zingawopseze moyo . Chifukwa chake, ndikofunikira kudziwa izi.

Ngakhale madokotala sangathe kuchiritsa Mastocytosis kwathunthu, amatha kuwongolera zizindikiro ndikuchiza mavuto aliwonse omwe angabuke.

Kodi mitundu ikuluikulu ya Mastocytosis ndi iti?

Pali mitundu iwiri ikuluikulu ya matendawa:

1. Cutaneous Mastocytosis: Izi nthawi zambiri zimachitika mwa makanda ndi ana aang'ono . Komabe, zimathanso kuchitika kwa akuluakulu. Chomwe chimachitika apa ndichakuti "maselo a mast" osazolowereka amasonkhana pakhungu, zomwe zimapangitsa kuti matuza ndi mabala ofiira, ofiira akuda, abulauni, kapena amitundu yosiyanasiyana aziwoneka ngati akuyabwa. Zili ngati mwana wamng'ono mwadzidzidzi amakhala ndi mabala ofiira ambiri pathupi lawo ndipo amawakanda mosalekeza.

2. Matenda a m'thupi otchedwa Systemic Mastocytosis: Mtundu uwu umapezeka kwambiri mwa akuluakulu.Apa, "maselo a mast" osazolowereka amasonkhana m'ziwalo zamkati monga mafupa, mafupa, kugaya chakudya, ndi mapapo. Tangoganizirani, ngati maselowa asonkhana mochulukira mu mafupa, zingakhudze kapangidwe ka maselo athu a magazi. Komanso, ngati maselowa achuluka m'mimba, amatha kupanga asidi wambiri m'mimba ndikuyambitsa zilonda zam'mimba.

Kodi iyi ndi matenda ofala?

Ayi, izi ndi matenda osowa kwambiri. Malinga ndi kafukufuku, akuti munthu m'modzi yekha pa anthu 10,000 (10,000) kapena m'modzi pa anthu 20,000 (20,000) amadwala matendawa. Chifukwa chake, sizachilendo kuti si aliyense amene amadziwa za matendawa.

Kodi zizindikiro za Mastocytosis ndi ziti?

Pamene "maselo a mast" awa akuchulukirachulukira, zizindikiro zosiyanasiyana zimatha kuchitika. Ngakhale zizindikirozi zingakhale zochepa kwambiri kwa anthu ena, zimatha kukhala zoopsa kwa ena.

• Kupweteka kwa mafupa: Kumva ngati mafupa anu akupweteka.
• Kutsegula m'mimba (kupweteka m'mimba): Kupita kuchimbudzi pafupipafupi.
• Kukomoka (monga kutaya chidziwitso): Mwadzidzidzi, maso anu amasanduka abuluu ndipo mukuoneka kuti mwataya chidziwitso.
• Kukhala ndi nkhawa komanso mantha nthawi zonse: Kumva kuda nkhawa popanda chifukwa.
• Kutsuka: Kufiira kwadzidzidzi kwa khungu lonse m'thupi.
• Matuza kapena mawanga pakhungu: Monga tidanenera kale.
• Mutu: Kupweteka mutu pafupipafupi.
• Chizungulire chomwe chimabwera chifukwa cha kuthamanga kwa magazi: Kumva chizungulire munthu akaimirira kuchokera pamalo oyimirira.
• Kupweteka kwa mafupa: Kupweteka kwa mafupa.
• Madontho ofiira kapena abulauni pakhungu: Izi zitha kuyabwa kapena ayi.

Kodi Mastocytosis imayamba pa msinkhu uti?

Zimasiyana malinga ndi mtundu wa matenda. Kawirikawiri:

• Mastocytosis ya m'matupi: Izi zingakhudze ngakhale makanda obadwa kumene.
• Mastocytosis Yachilengedwe: Nthawi zambiri imakhudza akuluakulu azaka zopitilira 50.

Kodi chifukwa chake ndi chiyani?

`(Mastocytosis)` si chinthu chomwe timabadwa nacho. Chimachitika chifukwa cha kusintha kwa majini otchedwa `(majini a KIT)`. `(majini a KIT)` awa ndi majini omwe amathandiza mitundu ina ya maselo, monga maselo athu a m'magazi, `(mast cells)`, kukula. Mu `(Mastocytosis), majini a `(KIT)` awa osinthika amapereka chizindikiro cholakwika ku `(mast cells)` kuti "achuluke kwambiri ndikukula mosalamulirika."

Kodi ndi zinthu ziti zomwe zimayambitsa mastocytosis?

Izi zitha kusiyana malinga ndi munthu. Si aliyense amene ali ndi zinthu zomwe zimayambitsa matendawa. Komabe, pali zinthu zina zomwe nthawi zambiri zimatha kuwonjezera zizindikiro:

• Kukanda kapena kukanda khungu: Izi zingachitikirenso anthu ena pongovala zovala zolimba.
• Kuchita masewera olimbitsa thupi komanso kuchita masewera olimbitsa thupi mopitirira muyeso.
• Kulumidwa ndi tizilombo:Makamaka nyama monga nyerere, mavu, ndi njuchi.
• Kumwa mowa.
• Zakudya zina: Makamaka zakudya zokometsera, zokometsera kwambiri.
• Mankhwala ena: Mwachitsanzo, mankhwala ochepetsa ululu otchedwa ``NSAIDs`` (mankhwala osagwiritsa ntchito ma steroidal anti-inflammatory drugs), mankhwala opumitsa minofu, ndi mankhwala oletsa ululu ``(anesthesia)``.
• Kusintha kwadzidzidzi kwa kutentha: Monga kudumphira m'madzi ozizira kwambiri.
• Kupsinjika maganizo kapena thupi: Izi nthawi zambiri zimakhudza kwambiri.

Kodi mavuto omwe angakhalepo chifukwa cha Mastocytosis ndi ati?

Matendawa angayambitse mavuto ena azaumoyo, kuphatikizapo:

• Matenda a Osteoporosis: Izi zimapangitsa mafupa kufooka komanso kusweka mosavuta.
• Mavuto a chiwindi: Matenda omwe chiwindi chimatupa ndipo sichigwira ntchito bwino.
• Cytopenia: Kulephera kwa thupi kupanga maselo okwanira a magazi.
• Matenda opatsirana pafupipafupi.

Kodi Mastocytosis imapezeka bwanji?

Dokotala wanu adzakufunsani za zizindikiro zanu ndikuwunika khungu lanu. Kuphatikiza apo, angachite mayeso monga:

• Kuyezetsa magazi: Yang'anani mulingo wa enzyme yotchedwa ``tryptase`` m'magazi anu. ``tryptase`` iyi ndi chinthu chomwe ``mast cells`` amachitulutsa akamayankha adani.
• Kujambula mafupa: Kufufuza ngati mafupa awonongeka.
• Kufufuza za mafupa: Chitsanzo cha mafupa chimatengedwa ndikuyang'aniridwa ngati pali maselo a m'mafupa osazolowereka.
• Mayeso a majini: Ngati muli ndi Systemic Mastocytosis, mutha kuyesedwa kusintha kwa majini a KIT.

Kodi mankhwala a Mastocytosis ndi ati?

Njira zochiritsira zimasiyana malinga ndi mtundu wa matenda ndi zizindikiro zanu. Madokotala nthawi zambiri amagwiritsa ntchito mankhwala ndi njira zina zochiritsira kuti achepetse zizindikiro.

Mitundu ya mankhwala omwe amagwiritsidwa ntchito pa Mastocytosis:

• Mankhwala oletsa asidi (H2 blockers) a matenda am'mimba: Pa zinthu monga kutupa m'mimba ndi gastritis.
• Mankhwala oletsa kutupa: Amachepetsa zizindikiro za ziwengo pakhungu monga kuyabwa ndi kufiira.
• Ma bisphosphonates a osteoporosis: Kulimbitsa mafupa.
• Corticosteroids: Amachepetsa kutupa.
• Ma antibodies a monoclonal: makamaka mankhwala monga omalizumab (Xolair®).
• Mankhwala ochepetsa ululu .

Mankhwala ena:

• Chithandizo cha kuwala kwa Ultraviolet (UV): Chepetsani mawanga akuda pakhungu.
• Chithandizo cholunjika .
• Epinephrine yothandiza pa anaphylaxis:Chithandizo chadzidzidzi cha vuto lalikulu la ziwengo.
• Chemotherapy: Izi zimachitika kawirikawiri ndipo zimaperekedwa kokha ngati Mastocytosis yasanduka khansa.
• Kusamutsa maselo oyambira a allogeneic (mafupa): Izi zimaganiziridwanso m'matenda ovuta kwambiri komanso ovuta a mastocytosis. Anthu ambiri safunikira izi.

Kodi pali zovuta zilizonse kapena zotsatirapo zina za chithandizochi?

Inde, monga momwe zimakhalira ndi chithandizo chilichonse, pali zotsatirapo zina zomwe zingachitike ndi chithandizo cha Mastocytosis. Zina zingakhale zazing'ono, pomwe zina zingakhale zoopsa kwambiri. Ngati muli ndi Mastocytosis, dokotala wanu adzakufotokozerani chithandizo chomwe mukulandira komanso zotsatirapo zake.

Kodi mastocytosis ingachiritsidwe kwathunthu?

Kawirikawiri, mastocytosis imaonedwa ngati matenda omwe sangachiritsidwe kwathunthu, koma amatha kuthandizidwa poletsa zizindikiro ndi kuchiza mavuto .

Chithandizo chokhacho chomwe chingachiritse izi ndi "kuika maselo oyambira a allogeneic (mafupa)" omwe atchulidwa kale. Komabe, ngakhale zimenezo zimangolimbikitsidwa kwa odwala omwe ali ndi matenda ovuta kwambiri komanso ovuta.

Kodi mastocytosis imakula pakapita nthawi?

Ngati sanalandire chithandizo, zizindikiro zimatha kuipiraipira pakapita nthawi, makamaka kwa munthu amene ali ndi matenda a mastocytosis , chifukwa maselo a mast osazolowereka amapitirira kukhudza mafupa ndi ziwalo zamkati.

Kodi mastocytosis ingapewedwe?

Mwatsoka, ayi. Popeza izi zimachitika chifukwa cha kusintha kwa majini a KIT, palibe njira yopewera. Komabe, ngati muli ndi Mastocytosis, mutha kuwongolera zizindikiro zanu podziwa bwino zomwe zimayambitsa ziwengo zanu ndikuzipewa momwe mungathere.

Mwachitsanzo, ngati muli ndi vuto la mankhwala enaake, ndi bwino kuvala chibangili cha chenjezo chachipatala chomwe chili ndi mndandanda wa mankhwalawo. Izi zithandiza ena kudziwa mankhwala omwe simuyenera kumwa pakagwa mwadzidzidzi.

Ngati muli ndi matenda a Systemic Mastocytosis, ndikofunikira nthawi zonse kunyamula syringe yodzibaya yokha yokhala ndi epinephrine. Itha kugwiritsidwa ntchito pochiza matenda oopsa komanso oopsa monga anaphylactic shock.

Kodi ndimadzisamalira bwanji? (Mastocytosis) Pamene ndikukhala ndi...

Popeza mastocytosis ndi matenda omwe sangachiritsidwe kwathunthu, mungafunike kukhala nawo kwakanthawi. Zingakhale zovuta. Komabe, nazi zina zomwe zingakuthandizeni:

• Dziwani bwino chomwe chimayambitsa zizindikiro zanu.Zomwe zimayambitsa matendawa zimasiyana kwa aliyense. Mungafunike kulemba tsiku ndi tsiku ndikulemba nthawi yomwe zizindikiro zanu zikuipiraipira, zomwe mudadya ndi kumwa, komanso zomwe mudachita panthawiyo.
• Kupsinjika maganizo kungapangitse zizindikirozi kukhala zoipitsitsa. Ngati mukufuna thandizo polimbana ndi kupsinjika maganizo, funsani dokotala wanu za mapulogalamu othana ndi kupsinjika maganizo. Zinthu monga kusinkhasinkha ndi yoga zingathandize.
• Valani chibangili chochenjeza zachipatala. Chiyenera kulemba matenda anu ndi mankhwala aliwonse omwe simuyenera kumwa.
• Nthawi zonse nyamulani singano ya epinephrine auto-injector. Ikhoza kupulumutsa moyo ngati mutakumana ndi vuto lalikulu la ziwengo.

Ndiyenera kupita liti kwa dokotala wanga?

Mudzapita kukayezetsa dokotala nthawi zonse . Adzayang'anira zizindikiro zanu ndikusintha chithandizo chanu ngati pakufunika kutero. Ngati muyamba zizindikiro zatsopano, kapena ngati zizindikiro zanu zikuipiraipira, uzani dokotala wanu nthawi yomweyo.

Kodi ndiyenera kupita ku Chipinda cha Zadzidzidzi liti?

Ngati muli ndi vuto lalikulu la ziwengo lomwe silingathe kuthetsedwa ndi mankhwala, pitani kuchipatala mwamsanga. Izi zikutanthauza kuti, ngati mukukumana ndi zizindikiro monga kupuma movutikira, kutsekeka pakhosi, chizungulire chachikulu, kapena kutaya chikumbumtima.

Ndi mafunso ati omwe ndiyenera kufunsa dokotala wanga?

Ngati muli ndi matenda a Mastocytosis, ndi bwino kufunsa dokotala mafunso monga awa:

• Kodi ndili ndi mtundu wanji wa Mastocytosis?
• Ndi mankhwala ati omwe alipo a mtundu womwe ndili nawo?
• Kodi chithandizochi chidzathetsa zizindikiro zanga zonse?
• Ndi zizindikiro zina ziti zomwe zingasonyeze kuti vuto langa likuipiraipira?
• Kodi ndiyenera kumwa mankhwala kwamuyaya?
• Ngati ndili ndi mawonekedwe ovuta kwambiri, kodi ndikuyembekezera chiyani?
• Kodi pali mayeso aliwonse azachipatala omwe ndingatenge nawo mbali?

Pomaliza, zomwe muyenera kukumbukira (Uthenga Wopita Nawo Kunyumba)

Matenda a mastocytosis ndi matenda osowa omwe amayambitsa kukula kosazolowereka komanso kosalamulirika kwa maselo a mast m'thupi. Amatha kukhudza khungu ndi ziwalo zamkati. Anthu ambiri amatha kuthana ndi zizindikiro zawo pozindikira ndikupewa zomwe zimayambitsa matendawa komanso kumwa mankhwala. Ndikofunikiranso kukhala ndi jakisoni wa epinephrine pafupi kuti muchiritse matenda oopsa a ziwengo.

Ngakhale kuti uwu ndi matenda omwe sangachiritsidwe kwathunthu, ndi upangiri woyenera wachipatala ndi chithandizo, mutha kuyesa kuwongolera zizindikiro ndikukhala moyo wabwinobwino. Ngati muli ndi mafunso ena okhudza izi, musazengereze kulankhula ndi dokotala wanu. Adzakuthandizani.

Mastocytosis , maselo a mast, histamine, ziwengo, matenda a pakhungu, chitetezo chamthupi, anaphylaxis