Tiyeni tiphunzire za katemera wa Natalizumab. Kodi mwapatsidwanso mankhwala awa?

Dokotala akakulangizani katemera wotchedwa Natalizumab kwa inu kapena munthu amene mumamudziwa, ndi zachilendo kukhala ndi mafunso ambiri okhudza katemerayu. "Kodi izi zimaperekedwa chifukwa cha matenda otani?", "Kodi zidzachiritsadi?", "Kodi pali zotsatirapo zina?" Mwina mukudzifunsanso chimodzimodzi. Chifukwa chake, lero, tiyeni tikambirane za mankhwala otchedwa Natalizumab m'njira yosavuta yomwe mungamvetse.

Kodi Natalizumab ndi mankhwala amtundu wanji?

Mwachidule, Natalizumab ndi mankhwala. Izi zikutanthauza kuti, sichichiritsa matendawa kwathunthu, koma chimathandiza kuwongolera zizindikiro ndikuchepetsa kuchuluka kwa kuphulika kwa matenda. Mankhwalawa amagwiritsidwa ntchito makamaka pa matenda awiri.

1. Pa vuto la Relapsing Multiple Sclerosis:

Taganizirani izi motere: dongosolo lathu la mitsempha lili ngati waya wonyamula zizindikiro zamagetsi. Mu matenda otchedwa multiple sclerosis, chophimba choteteza (myelin) chozungulira ulusi wa mitsempha iyi chimawonongeka. Kenako zizindikiro zamagetsi sizimayenda bwino. Izi zingayambitse zizindikiro monga kuvutika kuyenda, mavuto a maso, kuvutika kulankhula, komanso kutaya chidziwitso. Natalizumab imagwira ntchito poletsa kuwonongeka kumeneku ndikuchepetsa kuchuluka kwa kufalikira kwa matendawa.

2. Pa matenda a Crohn:

Matenda a Crohn ndi matenda otupa omwe amakhudza kugaya chakudya, makamaka matumbo. Angayambitse zizindikiro monga kupweteka m'mimba, kudzimbidwa, komanso kuchepa thupi. Madokotala angalimbikitse kugwiritsa ntchito mankhwala a Natalizumab pamene mankhwala ena sanagwire ntchito.

Chofunika kwambiri ndi chakuti dokotala wanu asankhe ngati mankhwalawa ndi oyenera kwa inu komanso nthawi yomwe muyenera kumwa. Chifukwa chake, ndikofunikira kwambiri kutsatira malangizo ake.

Madokotala angagwiritsenso ntchito mankhwalawa pa matenda ena. Ngati muli ndi mafunso okhudza mankhwalawa, funsani dokotala wanu kapena wamankhwala. Dzina la mankhwala awa ndi Tysabri.

Kodi ndiyenera kumuuza chiyani dokotala ndisanayambe kumwa mankhwalawa?

Musanayambe kumwa Natalizumab, ndikofunikira kuuza gulu lanu lazachipatala (monga madokotala ndi anamwino) zambiri, chifukwa izi zidzawathandiza kusankha ngati mankhwalawa ndi oyenera kwa inu kapena ngati muyenera kutenga njira zina zodzitetezera.

Ngati muli ndi zinthu izi, nenani motsimikiza kuti:

• Mavuto a chitetezo chamthupi: Ngati muli ndi kufooka kulikonse kapena vuto lililonse ndi chitetezo chamthupi chanu cholimbana ndi matenda (chitetezo chamthupi), tiuzeni za vutoli. Izi zili choncho chifukwa mankhwalawa amakhudzanso chitetezo chamthupi, choncho ndikofunikira kudziwa za vutoli.
• Matenda otchedwa Progressive Multifocal Leukoencephalopathy (PML):Uwu ndi matenda osowa kwambiri koma oopsa kwambiri muubongo. Ngati mudadwalapo vutoli, muyenera kutiuza.
• Ngati muli ndi vuto la ziwengo chifukwa cha Natalizumab kapena mankhwala ena, zakudya, utoto, kapena zosungira: Anthu ena akhoza kukhala ndi ziwengo chifukwa cha mankhwala enaake. Choncho ngati munakhalapo ndi ziwengo chifukwa cha mankhwalawa kapena mankhwala ena aliwonse, uzani dokotala wanu.
• Ngati muli ndi pakati kapena mukufuna kutenga mimba: Mankhwala ena akhoza kukhala oopsa kwa mwana panthawi ya mimba, choncho ndikofunikira kulankhula ndi dokotala wanu za izi.
• Ngati ndinu mayi woyamwitsa: Mankhwala ena amatha kupita kwa mwana wanu kudzera mu mkaka wa m'mawere. Choncho uzaninso dokotala wanu za izi.

Kuwonjezera pa zinthu izi, ndikofunikiranso kuuza dokotala wanu za mankhwala ena aliwonse omwe mukumwa (mankhwala olembedwa ndi dokotala, ogulitsidwa pamtengo wotsika, mankhwala achikhalidwe, mavitamini, ndi mankhwala azitsamba).

Kodi mumagwiritsa ntchito bwanji mankhwalawa?

Natalizumab imaperekedwa ngati mankhwala olowetsedwa m'mitsempha. Zili ngati kupereka madzi amchere. Simungachite izi kunyumba. Imaperekedwa kwa inu ndi katswiri wazachipatala, monga dokotala kapena namwino, kuchipatala kapena ku chipatala.

Mankhwalawa nthawi zambiri amaperekedwa kamodzi pamwezi, koma izi zimatha kusiyana malinga ndi matenda anu.

Mukapatsidwa mankhwala awa, malo ogulitsira mankhwala adzakupatsani malangizo apadera (MedGuide) . Mudzalandira izi pamodzi ndi mankhwala aliwonse, nthawi iliyonse mukalandira mankhwalawo. Ndikofunikira kwambiri kuwerenga izi mosamala. Zili ndi zambiri zokhudza mankhwalawo, zotsatira zake, ndi zinthu zomwe muyenera kusamala nazo. Ngati pali chilichonse chomwe simukumvetsa, musaope kufunsa dokotala wanu kapena wamankhwala.

Kodi mankhwala awa angaperekedwe kwa ana?

Mankhwalawa nthawi zambiri saloledwa kugwiritsidwa ntchito kwa ana. Ngati mukuganiza zogwiritsa ntchito mankhwalawa kwa mwana wanu, muyenera kulankhula ndi dokotala wa ana za vutoli.

Chochita ngati mwamwa mankhwala ochulukirapo? (Kupitirira muyeso)

Popeza izi zimaperekedwa kuchipatala, mwayi woti izi zichitike ndi wochepa. Komabe, ngati mukuganiza kuti mwamwa mankhwala ochulukirapo, imbani malo owongolera poizoni kapena chipinda chodzidzimutsa nthawi yomweyo.

Mankhwala awa ndi a inu nokha! Ichi ndi chinthu chomwe dokotala wakupatsani chifukwa cha matenda anu ndi thupi lanu. Chifukwa chake, musagawane mankhwalawa ndi wina aliyense.

Kodi mumatani ngati mwaphonya mlingo wa mankhwala?

Ndikofunikira kwambiri kumwa mankhwalawa pa nthawi yake. Ngati mwaphonya nthawi yokumana ndi dokotala, imbani dokotala wanu kapena katswiri wa zaumoyo nthawi yomweyo. Adzakuuzani choti muchite kenako. Musapange zisankho nokha.

Ndi mankhwala ena ati omwe angagwirizane (mkangano) ndi mankhwalawa?

Iyi ndi mfundo yofunika kwambiri. Pali mankhwala ena omwe angayambitse mavuto akamwedwa ndi Natalizumab. Chifukwa chake, ndikofunikira kuti dokotala wanu adziwe mankhwala onse omwe mukumwa.

Musamwe Natalizumab ndi mankhwala otsatirawa:

• Mankhwala achilengedwe monga adalimumab, certolizumab, etanercept, golimumab, ndi infliximab, amakhudzanso chitetezo cha mthupi, kotero amatha kuwonjezera chiopsezo cha matenda oopsa.

Mankhwalawa angagwirizanenso ndi Natalizumab:

• Azathioprine
• Cyclosporine
• Ma Interferon
• 6-mercaptopurine
• Methotrexate
• Mankhwala ena omwe amachepetsa mwayi wanu wolimbana ndi matenda
• Mankhwala a steroid - zitsanzo: prednisone kapena cortisone
• Katemera - Samalani mukalandira katemera wamoyo, makamaka. Lankhulani ndi dokotala wanu za izi.

Mndandandawu sungakhale ndi mankhwala onse. Chifukwa chake, uzani dokotala wanu za mankhwala onse omwe mumamwa (kuphatikizapo zitsamba, mankhwala osaperekedwa ndi dokotala, ndi zowonjezera zakudya), komanso ngati mumasuta fodya, mumamwa mowa, kapena mumagwiritsa ntchito mankhwala osokoneza bongo. Zinthu zina zingakhudze mankhwala anu.

Ndi zinthu ziti zomwe muyenera kusamala nazo mukamamwa mankhwalawa?

Mukamwa mankhwalawa, dokotala wanu adzakuyang'anirani nthawi zonse. Onetsetsani kuti mwaonana ndi dokotala wanu pa masiku omwe akonzedwa. Uzani dokotala wanu ngati zizindikiro zanu sizikusintha, ngati zikuipiraipira, kapena ngati zikupitirira.

Pewani anthu odwala. Mankhwalawa angakhudze chitetezo chamthupi chanu pang'ono, zomwe zingakupangitseni kuti mutenge matenda ambiri. Ngati mukumva zizindikiro monga malungo, kuzizira, kupweteka pakhosi, kapena mphuno yotuluka madzi, imbani dokotala nthawi yomweyo kuti akupatseni malangizo. Musapite kukatenga mankhwala nokha.

Chenjezo lofunika kwambiri: chiopsezo cha matenda a muubongo (PML)

Izi zingamveke zoopsa pang'ono, koma ndikofunikira kudziwa. Kwa odwala ena, ngakhale kuti nthawi zambiri, mankhwala a Natalizumab angayambitse matenda oopsa muubongo otchedwa Progressive Multifocal Leukoencephalopathy (PML) . Izi zitha kupha.

Chifukwa chake, ngati mukukumana ndi zizindikiro izi, muyenera kuuza dokotala wanu nthawi yomweyo:

• Kusintha kwa masomphenya (monga, kuwona zinthu modzidzimutsa, kuona zinthu ziwiri)
• Mavuto oganiza (monga kusokonezeka maganizo, kuiwala zinthu, kuvutika kupanga zisankho)
• Mavuto olankhula (monga kusokoneza mawu, kulephera kulankhula momveka bwino)
• Kuvuta kuyenda (monga kulephera kuyenda bwino, kulephera kuyenda bwino)
• Kuvuta kuyima

Ngati simungathe kulankhula ndi dokotala wanu, pitani kuchipatala mwamsanga. Musanyalanyaze izi. Zizindikirozi zitha kukhala zizindikiro za PML kapena ayi. Koma ndi bwino kupita kukayezetsa.

Kodi zotsatirapo zake zingakhale zotani chifukwa cha mankhwalawa?

Monga mankhwala ena aliwonse, Natalizumab ingayambitse zotsatira zina zoyipa. Si aliyense amene amalandira, koma ndibwino kudziwa za izo.

Zotsatirapo zoyipa zomwe ziyenera kufotokozedwa kwa dokotala wanu kapena katswiri wa zaumoyo nthawi yomweyo:

• Matenda a ziwengo: Ziphuphu pakhungu, kuyabwa, ziphuphu, kutupa kwa nkhope, milomo, ndi lilime.
• Kuvuta kupuma.
• Kusintha kwa masomphenya.
• Kupweteka pachifuwa.
• Kusokonezeka, nkhawa.
• Kuvutika maganizo, kumva ngati kuti mukutaya chimwemwe chanu.
• Chizungulire.
• Kumva kufooka; mutu wopepuka; kugwa.
• Kumva kudwala kapena zizindikiro zofanana ndi chimfine.
• Kutaya kukumbukira.
• Azimayi omwe sasamba nthawi yawo yobereka (Osasamba nthawi yobereka).
• Kufooka kwa minofu.
• Mavuto okhudzana ndi kukhazikika, kulankhula, kapena kuyenda. (Izi zitha kukhalanso zizindikiro za PML, choncho samalani kwambiri!)
• Zizindikiro za kuvulala kwa chiwindi: Mkodzo wakuda wachikasu kapena bulauni; kumva kudwala, kutentha thupi; ndowe zotumbululuka; kusowa chilakolako; nseru; kupweteka kumtunda kwa mimba; kutopa kapena kufooka kosazolowereka; chikasu cha maso kapena khungu.
• Maganizo ofuna kudzipha, kusintha kwa maganizo.
• Kutupa kapena kutuluka magazi kosazolowereka.
• Wofooka kapena wotopa kwambiri.

Zotsatirapo zomwe nthawi zambiri sizifuna upangiri wa dokotala (koma ziyenera kufotokozedwa kwa dokotala ngati zikupitirira kapena zikuvutitsa):

• Mutu
• Kupweteka kwa mafupa
• Kupweteka kwa minofu
• Kupweteka kwa minofu
• Kusanza, kusanza
• Ululu, kufiira, kapena kukwiya pamalo pomwe panabayidwa jakisoni
• Kutopa

Mndandandawu sungakhale ndi zotsatirapo zonse zoyipa. Ngati muwona china chake chachilendo kuwonjezera pa izi, funsani dokotala wanu.

Kodi mankhwala awa mumasunga kuti?

Simudzaloledwa kutenga mankhwala awa kunyumba. Amapezeka ndipo amaperekedwa kwa inu kuchipatala kapena ku chipatala. Chifukwa chake, simuyenera kuda nkhawa ndi momwe mungasungire.

Pomaliza, zinthu zoti muzikumbukira (Uthenga Wopita Nawo Kunyumba)

Chabwino, takambirana zambiri za Natalizumab. Ngati muli ndi mafunso ena okhudza mankhwalawa, musaope kufunsa dokotala wanu, namwino, kapena wamankhwala. Adzakuthandizani.

Chofunika kwambiri ndikumwa mankhwala monga momwe dokotala wanu wanenera, panthawi yoyenera, komanso m'njira yoyenera. Dziwani zotsatirapo zake, makamaka zizindikiro za matenda otchedwa PML. Ngati muwona china chake chachilendo, uzani dokotala wanu nthawi yomweyo.

Mankhwalawa angakuthandizeni kuwongolera vuto lanu. Choncho, khalani olimba mtima ndipo gwirizanani ndi dokotala paulendowu. Ndikukufunirani kuti muchire mwachangu!

Natalizumab , Multiple Sclerosis, Matenda a Crohn, PML, Zotsatira zoyipa za mankhwala, Immunotherapy, Tysabri