Tikayang'ana cholesterol yathu, nthawi zambiri timangoyang'ana "cholesterol yabwino" (HDL) ndi "cholesterol yoipa" (LDL), sichoncho? Koma kodi mumadziwa kuti pali mtundu wofunika kwambiri wa cholesterol womwe anthu ambiri salankhula, koma umabisika pakati? Iyi ndi Lipoprotein(a), kapena Lp(a) mwachidule. Chinthu chapadera pa izi ndichakuti imatsimikiziridwa ndi majini athu, zomwe zikutanthauza kuti imadutsa kuchokera ku mibadwomibadwo kupita ku mibadwomibadwo, osati ndi zomwe timadya, kumwa kapena kuchita masewera olimbitsa thupi. Mutha kukhala munthu wathanzi kwambiri, koma mulingo wanu wa Lp(a) ukhoza kukhala wokwera kwambiri.
Kodi Lipoprotein (a) kwenikweni ndi chiyani?
Mwachidule, ichi ndi tinthu tating'onoting'ono tomwe tili ndi cholesterol m'magazi mwathu. Koma vuto ndi izi ndikuti kuchuluka kwake kumatengera majini athu. Izi zikutanthauza kuti ngati amayi anu, abambo anu, kapena wina m'banja mwanu ali ndi vutoli, inunso muli ndi mwayi wokhala nalo. Akuti pafupifupi munthu m'modzi mwa anthu asanu aliwonse padziko lapansi ali ndi kuchuluka kwa Lp(a) m'magazi.
Kuopsa kwa izi ndikuti kukhala ndi Lp(a) yambiri kumawonjezera kwambiri chiopsezo cha matenda a mtima ndi sitiroko ali aang'ono. Nthawi zambiri, anthu amadziwa izi pokhapokha atadwala matenda a mtima kapena sitiroko. Izi zili choncho chifukwa chakuti lipid panel yokhazikika siiwonetsa Lp(a) iyi. Imafunika mayeso osiyana.
Mwachitsanzo, tenga nkhani ya Bernadette, mayi wazaka 66 amene amayenda makilomita pafupifupi 16 patsiku ndipo amadya zakudya zochokera ku zomera, kuphatikizapo ndiwo zamasamba ndi tofu. Mafuta ake a cholesterol nthawi zambiri anali abwino, koma kuchuluka kwa Lp(a) kwake kunali kokwera kasanu kuposa kuchuluka kwa chiopsezo. Izi zinali chifukwa cha majini ake. Amayi ake ndi agogo ake onse anamwalira ndi matenda a mtima.
"Vuto lalikulu kwa ine ndi nkhawa yokhala ndi izi. Ngakhale kuti ndikumva kudwala pang'ono, ndimaganiza kuti, 'Kodi uku ndi kudwala kwa mtima komwe ndidzakhala nako?'" akutero Bernadette.
Vuto ndi chiyembekezo chatsopano
Mpaka pano, palibe mankhwala enieni omwe avomerezedwa kuti achepetse kuchuluka kwa Lp(a). Izi zikutanthauza kuti ngakhale akudziwa kuti alipo, anthu ambiri akhala akukhala mwamantha, popanda chilichonse chomwe angachite. Zili ngati kukhala ndi bomba la nthawi m'thupi lawo lomwe lingaphulike nthawi iliyonse.
Koma tsopano zinthu zisintha!
Ofufuza zachipatala pakadali pano akufufuza mankhwala atsopano asanu omwe awonetsedwa m'maphunziro oyambirira kuti amachepetsa kwambiri kuchuluka kwa Lp(a). Ichi ndi chiyembekezo chachikulu kwa anthu mamiliyoni ambiri omwe ali ndi kuchuluka kwa Lp(a) kokwera. Monga momwe wofufuza wamkulu Dr. Steven Nissen akunenera, " Musadandaule, mayankho akubwera. "
Mankhwala aposachedwa omwe ali mu gawo lofufuza
Mankhwala atsopanowa akadali m'magawo omaliza a kafukufuku (mayesero azachipatala). Ngati apambana, akhoza kukhala pamsika posachedwa. Tiyeni tiwone mankhwala amenewo ndi momwe akuyendera bwino.
| Dzina la Mankhwala | Mbali / Momwe mungapatsire | Zotsatira zomwe zikuyembekezeredwa |
|---|---|---|
| Pelacarsen | Jakisoni woperekedwa kamodzi pamwezi | Miyezo ya Lp(a) ikhoza kuchepetsedwa ndi pafupifupi 80%. |
| Olpasiran | Katemera amaperekedwa miyezi itatu iliyonse | Miyezo ya Lp(a) ikhoza kuchepetsedwa ndi oposa 95%. |
| Lepodisiran | Katemera mmodzi amene amakhala akugwira ntchito kwa pafupifupi chaka chimodzi | Milingo ya Lp(a) imatha kuchepetsedwa ndi pafupifupi 94% ndikusungidwa kwa nthawi yayitali. |
| Zerlasiran | Katemera woperekedwa kawirikawiri | Miyezo ya Lp(a) ikhoza kuchepetsedwa ndi pafupifupi 86%. |
| Muvalaplin | Piritsi la tsiku ndi tsiku | Miyezo ya Lp(a) ikhoza kuchepetsedwa ndi pafupifupi 86%. |
Kodi piritsi la Muvalaplin ndi lapadera bwanji?
Mwa izi, ofufuza ali ndi chiyembekezo chachikulu cha mankhwala otchedwa ``(Muvalaplin)'' chifukwa ngakhale mankhwala ena anayi ayenera kuperekedwa ngati jakisoni, awa akhoza kumwedwa ngati piritsi tsiku lililonse . Chifukwa chake, akhoza kukhala osavuta kwa odwala, komanso akhoza kukhala otsika mtengo.
Mankhwala ena amagwira ntchito poletsa jini yomwe imayambitsa kupanga Lp(a). Koma piritsi ili limagwira ntchito mosiyana. Limaletsa kupanga tinthu ta Lp(a) pakati. Izi zimathandiza kuti ligwire ntchito popanda kukhudza chiwindi ndikuchotsedwa m'thupi mwachangu ngati pakhala zotsatirapo zilizonse.
Nchifukwa chiyani tiyenera kuyesa Lp(a)?
Pamene mukuwerenga nkhaniyi, mwina mukudzifunsa kuti, 'Kodi inenso ndiyenera kukayezetsa izi?' Yankho ndi lakuti, inde! Muyenera kuganizira izi, makamaka ngati wina m'banja mwanu wakhala ndi matenda a mtima kapena sitiroko ali wamng'ono .
Bungwe la National Lipid Association tsopano likulangiza kuti aliyense azipimidwa mulingo wake wa Lp(a) kamodzi kokha m'moyo wake . Chifukwa ndi nkhani ya majini, mulingo susintha kwambiri pa moyo wake wonse. Kungopimidwa kamodzi kokha ndikokwanira.
Kuyeza magazi kumeneku ndi kosavuta kwambiri. Komabe, popeza sikuli mu lipoti lodziwika bwino la cholesterol, muyenera kufunsa dokotala wanu za izi musanayese mayesowa.
Kudziwa kuchuluka kwa Lp(a) yanu ndi gawo loyamba. Ngati kuli kokwera, musachite mantha. Ndi mankhwala atsopanowa omwe akubwera posachedwa, mudzatha kuwongolera chiopsezo chanu cha matenda a mtima ndi sitiroko. Mpaka nthawi imeneyo, ndikofunikira kuti zinthu zina zomwe zimayambitsa matenda monga kuthamanga kwa magazi, matenda ashuga, kusuta fodya, ndi kuchuluka kwa cholesterol ya LDL zisamayende bwino.
Uthenga Wopita Nawo Kunyumba
- Lipoprotein(a), kapena Lp(a), ndi mtundu wa cholesterol womwe umayendetsedwa ndi majini ndipo umawonjezera chiopsezo cha matenda a mtima.
- Izi sizikuphatikizidwa mu mayeso a cholesterol nthawi zonse (lipid profile), kotero muyenera kufunsa dokotala wanu za izi ndikuzifufuza mwachindunji.
- Ngati wina m'banja mwanu wakhala ndi matenda a mtima ali wamng'ono, ndikofunikira kwambiri kuti muyesedwe.
- Ngakhale pakadali pano palibe mankhwala enieni a Lp(a), mankhwala angapo omwe akuwonetsa zotsatira zabwino kwambiri ali kumapeto kwa kafukufuku. Izi ndi zabwino kwambiri.
- Ngati mwapeza kuti mulingo wanu wa Lp(a) ndi wokwera, musachite mantha, kambiranani ndi dokotala wanu, ndipo thandizani kuti zinthu zina zomwe zimayambitsa matenda a mtima zithe kuthetsedwa.
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