Kodi mukudziwa za khansa yosowa iyi yomwe imayamba m'mimba (peritoneal mesothelioma)?

Kodi nthawi zina mumamva kupweteka pang'ono kapena kutupa m'mimba mwanu? Kodi mumamva kutaya chilakolako cha chakudya komanso kuchepa thupi? Ngakhale nthawi zina timanyalanyaza zizindikirozi, zitha kukhala zizindikiro za matenda akuluakulu. Lero tikambirana za mtundu wa khansa womwe ndi wosowa pang'ono, koma umafunika kusamalidwa kwambiri. Umenewo ndi khansa yotchedwa `Peritoneal Mesothelioma`.

Kodi Mesothelioma ya Peritoneal ndi chiyani?

Mwachidule, `Peritoneal Mesothelioma` ndi khansa yomwe imayamba m'mimba mwathu, kutanthauza kuti, mu nembanemba yopyapyala yomwe imaphimba m'mimba, ponena zachipatala, `peritoneum`. Taganizirani izi, `peritoneum` iyi ili ngati chophimba chofewa choteteza ziwalo zofunika m'mimba mwathu, monga chiwindi, matumbo, ndi m'mimba.

Khansa iyi, monga mitundu ina ya mesothelioma, nthawi zambiri imagwirizanitsidwa ndi kugwiritsidwa ntchito kwa chinthu chotchedwa asbestos. Mwina munamvapo kuti asbestos ndi chinthu chomwe chimagwiritsidwa ntchito popanga zipangizo zina zomangira. Ndi yoopsa kwambiri chifukwa ulusi womwe uli mkati mwake ungayambitse mavuto akulu ngati muupumira kapena kuudya.

Mesothelioma ya m'mimba ndi khansa yoopsa komanso yofalikira mofulumira. Nthawi zambiri, ngakhale itapezeka, khansayo imakhala itafalikira kale m'mimba. Chifukwa chake, zimakhala zovuta kuizindikira msanga.

Kodi pali kusiyana kotani pakati pa mesothelioma ya m'mimba ndi mesothelioma ya m'mimba?

Ma `Peritoneal Mesothelioma` ndi `Pleural Mesothelioma` onse amakula m'maselo omwe ali m'mabowo ofunikira komanso ziwalo zamkati mwa thupi lathu.

• Mesothelioma ya m'mimba imayamba mu nembanemba yomwe imazungulira m'mimba ndikuzungulira ziwalo za m'mimba, ndiko kuti, peritoneum yomwe tatchula kale.
• Mesothelioma ya m'mapapo imayamba mu nembanemba yomwe imaphimba chifuwa, makamaka mapapo. Imatchedwa pleura.

Ma nembanemba onsewa amapangidwa ndi mtundu wapadera wa selo lotchedwa `mesothelial cells`. Ichi ndichifukwa chake khansa iyi imatchedwa `mesothelioma`.

Mitundu yonse iwiri ya mesothelioma nthawi zambiri imakhala yoopsa, zomwe zikutanthauza kuti ndi khansa . Maselo owopsa a mesothelioma amakula mwachangu komanso mosalamulirika, ndikuwononga minofu yathanzi yozungulira. Mesothelioma ya pleural ndi mtundu wofala kwambiri wa khansa kuposa mesothelioma ya peritoneal.

Ndani amene ali ndi mwayi waukulu wopeza matendawa? Kodi ndi ofala bwanji?

Aliyense akhoza kudwala `Peritoneal Mesothelioma`. Komabe, matendawa ndi osowa kwambiri pakati pa ana aang'ono. Nthawi zambiri, matendawa amapezeka mwa anthu azaka za m'ma 50.

Ngakhale kuti `Peritoneal Mesothelioma` ndi mtundu wachiwiri wofala kwambiri wa `Mesothelioma` (woyamba ndi `Pleural Mesothelioma`), ndi khansa yosowa kwambiri. `Peritoneal Mesothelioma` imapezeka pakati pa 10% ndi 20% ya odwala onse a `Mesothelioma`. Tangoganizirani, m'dziko ngati America, milandu yatsopano pakati pa 400 ndi 1000 yokha ya odwalawa imanenedwa chaka chilichonse. Chifukwa chake, ngakhale kuti odwalawa angakhalepo ku Sri Lanka, chiwerengerochi n'chochepa kwambiri.

Kodi zizindikiro za Peritoneal Mesothelioma ndi ziti? Kodi mungazindikire bwanji?

Iyi ndi mfundo yofunika kwambiri chifukwa nthawi zambiri, Peritoneal Mesothelioma siionetsa zizindikiro zilizonse kumayambiriro. Zizindikiro zimayamba kuonekera khansa ikafalikira m'mimba.

Chizindikiro chodziwika bwino ndi kuchulukana kwa madzi m'mimba. Izi zimatchedwanso `ascites`. Madzi akamawonjezeka, mimba imayamba kukula ndi kutupa. Chizindikiro chachiwiri chodziwika bwino ndi kupweteka m'mimba.

Zizindikiro zina zingaphatikizepo:

• Ascites : Zimakhala ngati mimba yadzaza komanso yolemera.
• Kutupa kapena kutupa m'mimba : Zovala zimatha kukhala zolimba.
• Kupweteka m'mimba : Uwu ukhoza kukhala ululu womwe umafalikira m'mimba yonse, kapena ukhoza kukhala ululu womwe umamveka pamalo amodzi okha.
• Mungamve chotupa chopweteka m'mimba mwanu .
• Kudzimbidwa kapena kutsekeka kwa matumbo : Zikumveka ngati mimba yanu yatupa ndipo mukuvutika kutulutsa ndowe.
• Kusanza ndi kusanza .
• Malungo osamveka bwino komanso thukuta usiku .
• Kuchepetsa thupi kosayerekezeka .
• Chakudya chilibe kukoma .

Chofunika: Ngati mukupitiriza kukhala ndi chimodzi mwa zizindikiro izi, ndikofunikira kwambiri kuonana ndi dokotala kuti akupatseni upangiri. Musadandaule, si zizindikiro zonsezi zomwe zimayambitsidwa ndi khansa. Zikhozanso kuchitika ndi matenda ena ofala. Komabe, nthawi zonse ndi bwino kupita kuchipatala.

Kodi ndi zinthu ziti zomwe zimayambitsa matenda a Peritoneal Mesothelioma?

Chinthu chachikulu chomwe chimayambitsa matenda a mesothelioma ndi kukhudzana ndi asbestos. Asbestos ndi ulusi womwe umagwiritsidwa ntchito pomanga, mapaipi, ntchito zamagetsi, denga, mafakitale ena opanga zinthu, komanso makampani opanga magalimoto. Anthu ambiri omwe amapanga mesothelioma ali ndi ntchito zomwe zimawapangitsa kuti azitha kukhudzana ndi asbestos.

Komabe, ngakhale kuti anthu ambiri omwe ali ndi vuto la pleural mesothelioma (mtundu womwe umakhudza mapapo) ali ndi mbiri ya kupezeka kwa asbestos, kulumikizana pakati pa peritoneal mesothelioma (mtundu womwe umakhudza mkati mwa mimba) ndi asbestos sikukudziwika bwino. Anthu ena omwe ali ndi vuto la peritoneal mesothelioma mwina sanakhalepo ndi mbiri ya kupezeka kwa asbestos pantchito. Izi zikufufuzidwabe.

Nazi zina mwa zinthu zomwe zimayambitsa matenda a `Peritoneal Mesothelioma`:

• Kupezeka kwa asbestos : Ulusi wa asbestos ukalowa m'malo mwathu, umauluka. Ukalowa m'thupi mwathu, umatha kulowa m'thupi mwathu kudzera m'kamwa ndi mphuno zathu, kupita ku peritoneum, ndikugona komweko. Ukapezeka, umawononga maselo a mesothelial, zomwe zimapangitsa kuti agawikane modabwitsa. Izi ndi zomwe zimapangitsa kuti zotupa za khansa zipangidwe. Tangoganizirani, mesothelioma imachitika patatha zaka zambiri munthu atapezeka ndi asbestos, nthawi zina mpaka zaka 40.
• Kupezeka kwa Silika ndi Erionite : Izi ndi mchere wofala womwe umapezeka m'nthaka. Kupezeka kwa izi kwapezekanso kuti kumagwirizana ndi Pleural ndi Peritoneal Mesothelioma.
• Kusintha kwa majini : Kafukufuku wina wasonyeza kuti ngati mukumana ndi asbestos ndipo muli ndi kusintha kwa majini ena, chiopsezo chanu chokhala ndi mesothelioma ya m'mimba chingachuluke. Chimodzi mwa kusintha kofala kwambiri ndi kusintha kwa jini yotchedwa BAP1. Jini iyi, yotchedwa BAP1, ndi yomwe imaletsa kukula kwa khansa.
• Kukhudzidwa ndi kuwala kwa dzuwa : Kulandira chithandizo cha radiation cha khansa ya m'mimba yomwe mudadwalapo kale kumaganiziridwanso kuti kumawonjezera chiopsezo chotenga mesothelioma ya m'mimba. Komabe, kafukufuku wowonjezereka akufunika kuti timvetsetse bwino ubale womwe ulipo pakati pa kuwala kwa dzuwa ndi chiopsezo cha mesothelioma.

Kodi mungadziwe bwanji ngati muli ndi Peritoneal Mesothelioma?

Kuzindikira matenda a Peritoneal Mesothelioma kungakhale kovuta, monga tanenera kale, chifukwa nthawi zambiri sikuwonetsa zizindikiro kumayambiriro. Zizindikiro zikaonekera, zimatha kufanana ndi matenda ena ofala a m'mimba kapena mitundu ina ya khansa. Chifukwa chake, matenda ofala awa nthawi zambiri amachotsedwa pofufuza matenda.

Mayeso otsatirawa atha kuchitidwa kuti adziwe matendawa:

• Kujambula kwa CT : Dokotala wanu angafune kuti mujambula kwa CT kuti athetse matenda ena omwe amayambitsa zizindikiro zofanana ndi za peritoneal mesothelioma, monga khansa ya ovarian kapena adenocarcinoma. Izi zingaphatikizepo kubaya utoto wotetezeka (contrast) m'magazi mwanu kuti zinthu monga zotupa m'mimba mwanu ziwonekere bwino pa kujambulako.
• Kujambula kwa MRI (Magnetic Resonance Imaging (MRI)) : MRI ingapereke tsatanetsatane wofanana ndi wa CT scan. MRI ingathe kuchitidwa ngati simungathe kuchita CT scan yokhala ndi kusiyana.
• Kuyezetsa magaziDokotala wanu angakuyezeni zizindikiro zina m'magazi mwanu, monga mapuloteni enaake, zomwe zingakhale chizindikiro cha chotupa cha khansa.
• Kusanthula madzi a m'mimba : Mu njirayi, dokotala wanu amaika singano m'mimba mwanu ndikutenga chitsanzo cha madziwo kuti aone ngati ali ndi zizindikiro za mesothelioma. Komabe, mayesowa ali ndi malire amodzi. Amangopereka chidziwitso chokhudza madzi omwe ali m'mimba mwanu, osati minofu yomwe ili m'mimba mwanu. Gawo la khansa limadalira kuchuluka kwa khansa yomwe yafalikira ku minofu.
• Kufufuza ndi CT-guided core needle biopsy kapena laparoscopic biopsy : Njira yokhayo yotsimikizira kuti muli ndi vuto la peritoneal mesothelioma ndikuchita biopsy. Pankhaniyi, dokotala wanu amagwiritsa ntchito kujambula zithunzi (monga scan) kuti apeze malo enieni a chotupa chanu. Kenako, pogwiritsa ntchito zida zochitira opaleshoni, amatenga chitsanzo cha minofu ndikutumiza ku labu kuti akayesedwe.

Kodi magawo a Peritoneal Mesothelioma ndi ati?

Magawo a khansa amasonyeza momwe matendawa apitira patsogolo komanso kufalikira. Njira yodziwika kwambiri yogwiritsira ntchito njira yoyezera khansa ya m'mimba ndi PCI (Peritoneal Cancer Index).

Mu njira ya `PCI`, mimba yanu imagawidwa m'magawo 13, ndipo gawo lililonse limapatsidwa chigoli kuyambira 0 mpaka 3.

• 0 amatanthauza kuti kulibe khansa m'dera limenelo.
• 3 ikutanthauza kuti gawo lonselo laphimbidwa ndi khansa.

Kenako dokotalayo amasonkhanitsa zigoli za gawo lililonse la matendawa ndikupeza gawo la khansa. Gawo 1 ndi gawo losapita patsogolo kwambiri. Gawo 4 ndi gawo lopita patsogolo kwambiri.

• Gawo 1: Zigoli za PCI kuyambira 1 mpaka 10.
• Gawo 2: Zigoli za PCI kuyambira 11 mpaka 20.
• Gawo 3: Zigoli za PCI kuyambira 21 mpaka 30.
• Gawo 4: Zigoli za PCI 31 mpaka 39.

Kodi chithandizo cha Mesothelioma ya Peritoneal ndi chiyani?

Njira zochiritsira zimadalira gawo la khansa yanu, thanzi lanu lonse, ndi zinthu zina zingapo.

Opaleshoni yochepetsa mitsempha ya m'magazi ndi chithandizo cha HIPEC (Cytoreduction ndi HIPEC)

Chithandizo chofala kwambiri cha peritoneal mesothelioma ndi kuphatikiza kwa opaleshoni yochepetsa kutupa ndi hyperthermic intraperitoneal chemotherapy (HIPEC) .

• Kuchepetsa Khansa : Iyi ndi opaleshoni yomwe imachotsa maselo a khansa m'mimba mwanu. Madokotala amachotsa zotupa zilizonse zomwe zimawoneka. Angathenso kuchotsa ziwalo za m'mimba ndi ziwalo zam'mimba zomwe khansa yafalikira.
• Mankhwala a chemotherapy a intraperitoneal hyperthermic (HIPEC): Uwu ndi mtundu wapadera wa chemotherapy womwe umaperekedwa pambuyo pa opaleshoni ya cytoreduction. Mankhwala a chemotherapy amatenthedwa kutentha kotetezeka ndipo amaperekedwa mwachindunji m'mimba. Kutentha kumeneku kumapangitsa kuti mankhwalawa akhale amphamvu kwambiri kuposa chemotherapy wamba. HIPEC imapha maselo ang'onoang'ono a khansa omwe mwina adasiyidwa omwe sanachotsedwe panthawi ya opaleshoni. HIPEC ilinso ndi zotsatirapo zochepa poyerekeza ndi chemotherapy wamba.

Opaleshoni yochepetsa kutupa ndi HIPEC ndi njira zazikulu komanso zovuta zomwe zingatenge maola opitilira 10. Komabe, kafukufuku wasonyeza kuti njira iyi yothandizira anthu omwe ali ndi Peritoneal Mesothelioma amakhala ndi moyo wautali.

Mankhwala a Chemotherapy

Ngati simungathe kuchitidwa opaleshoni yochepetsa mitsempha ya magazi ndi HIPEC, mutha kupatsidwa chithandizo chamankhwala ...

Chithandizo cha Immunotherapy

Mankhwala ochizira matenda otchedwa ``immune checkpoint inhibitors`` amathandiza chitetezo chanu cha mthupi kupeza ndikuwononga maselo a khansa. Mankhwalawa amagwiritsidwa ntchito kwambiri pochiza ``pleural mesothelioma``. Dokotala wanu angakupatseninso mankhwala ochizira ``peritoneal mesothelioma``.

Chithandizo cholunjika

Anthu ena omwe ali ndi peritoneal mesothelioma akhoza kukhala ndi kusintha kwa majini m'maselo awo a khansa. Izi zitha kuchiritsidwa ndi mankhwala ochizira. Mankhwala ochizira amagwira ntchito pochizira mwachindunji kusintha kwa majini komwe kumapangitsa maselo athanzi kukhala maselo a khansa. Mankhwalawa angapezeke kudzera mwa dokotala wanu wa khansa, kapena kudzera mu maphunziro otchedwa mayeso azachipatala omwe amayesa chitetezo ndi kugwira ntchito kwa mankhwala atsopano. Ndikofunikira kuchita mayeso a majini (mayeso a majini) pa minofu ya khansa kuchokera ku biopsy yanu kuti muwone ngati khansa yanu ili ndi kusintha kwa majini komwe kungachitike.

Chisamaliro cha kupweteka kwa mtima

Pofuna kukuthandizani kuthana ndi zizindikiro za khansa komanso zotsatirapo zake, dokotala wanu angakulangizeni chithandizo chochepetsa ululu. Ngati simuli bwino mokwanira kuti muchite opaleshoni, kapena ngati khansa yanu yafika pachimake, chithandizo chochepetsa ululu chingakhale njira yabwino kwambiri kwa inu. Chithandizo chochepetsa ululu chingaphatikizeponso njira monga paracentesis, yomwe imachotsa madzi m'mimba. Izi zingathandize kuchepetsa ululu ndi ululu womwe umabwera chifukwa cha kuchuluka kwa madzi m'thupi.

Kodi mungachepetse bwanji chiopsezo chotenga matendawa?

Njira yokhayo yochepetsera chiopsezo cha Mesothelioma ya Peritoneal ndiKupewa kukhudzana ndi asibesitosi. M'zaka za m'ma 1970, mabungwe monga Environmental Protection Agency (EPA) ku United States adakhazikitsa malamulo okhudza kugwiritsa ntchito asibesitosi. Komabe, nyumba zomwe zinamangidwa malamulowo asanayambe kugwira ntchito zingakhalebe ndi asibesitosi. Ngati ulusi wa asibesitosi wasokonezedwa, ukhoza kukhala wouluka ndikukhala woopsa kwambiri.

Kuti muchepetse chiopsezo chanu, pewani kukonza kapena kusintha zinthu zomwe zingakupangitseni kukhudzidwa ndi asbestos. M'malo mwake, lembani katswiri, monga katswiri wochotsa asbestos, kuti agwire ntchito yotereyi.

Kodi mungakhale ndi chiyembekezo chotani mukakhala ndi Peritoneal Mesothelioma?

Matenda a mesothelioma m'mimba si matenda ochiritsika kwathunthu. Komabe, chithandizo chingakulitse moyo wanu komanso kukupangitsani kuti mupumule kwa nthawi yayitali. Kugwira ntchito ndi gulu la madokotala a khansa omwe ali akatswiri pochiza mesothelioma kungathandize kuti zotsatira za chithandizo chanu ziwonjezeke. Kugwira ntchito ndi akatswiri osamalira odwala ofooka kungakuthandizeninso kukhala ndi moyo wabwino pamene mukukhala ndi matenda a khansa.

Ndi zinthu ziti zomwe zimakhudza momwe matenda anu angayambire?

Kuyezetsa matenda anu kumadalira zinthu zingapo:

• Mtundu wa selo : Pali mitundu itatu ya maselo omwe amatha kukhala zotupa. Mtundu wofala kwambiri, wotchedwa maselo a epithelioid, uli ndi chiyembekezo chabwino kuposa mitundu ina iwiri ya maselo, maselo a sarcomatoid ndi maselo a biphasic.
• Gawo la mesothelioma yanu : Ngati matendawa apezeka ndi kuchiritsidwa msanga, mwina mudzakhala ndi zotsatira zabwino.
• Jenda lanu : Ponena za Peritoneal Mesothelioma, akazi awonetsedwa kuti ali ndi chiyembekezo chabwino kuposa amuna.
• Kuchotsa ziphuphu zonse : Ngati dokotala wanu angathe kuchotsa ziphuphu zonse kwathunthu, ndiye kuti matenda anu angakhale abwino.
• Thrombocytosis : Ngati muli ndi thrombocytosis, matenda anu angakhale oipa. Thrombocytosis ndi matenda omwe mumakhala ndi ma platelet ambiri m'magazi anu. Ma platelet ndi maselo omwe amathandiza magazi kuundana.

Kodi mungakhale ndi nthawi yayitali bwanji ndi Peritoneal Mesothelioma?

Anthu omwe apezeka ndi Peritoneal Mesothelioma nthawi zambiri amakhala ndi moyo kwa miyezi pafupifupi 6 mpaka 12 popanda chithandizo. Komabe, akalandira chithandizo, kuchuluka kwa moyo kumakhala bwino kwambiri. Odwala Peritoneal Mesothelioma omwe amachitidwa opaleshoni yochotsa maselo m'thupi ndi HIPEC amakhala ndi moyo kwa zaka ziwiri mpaka zisanu ndi chimodzi atapezeka ndi matendawa. Anthu ena amakhala ndi moyo wautali kuposa pamenepa.

Komabe, nthawi yanu yoti mudziwe matenda imadalira zinthu zingapo. Dokotala wanu ndiye munthu wabwino kwambiri womvetsetsa zinthu zomwe zingakhudze nthawi yanu yoti mudziwe matenda, kutengera njira zomwe mungasankhe pochiza matenda.

Kodi ndi mafunso otani ofunika kufunsa dokotala wanu?

Ngati mwapezeka ndi Peritoneal Mesothelioma, funsani dokotala wanu za:

• "Kodi madokotala apadera ndani amene angandithandize?"
• "Kodi ndibwino kuti ndipeze thandizo kuchokera ku gulu lothandiza odwala ovutika maganizo?"
• "Ndi mtundu wanji wa mesothelioma womwe ndili nawo?"
• "Khansa yanga yafalikira mpaka pati? (Ndiye kuti, siteji yake ndi iti?)"
• "Ndi njira ziti zochiritsira zomwe ndili nazo?"
• "Kodi pali 'mayesero azachipatala' (maphunziro oyesa mankhwala atsopano) omwe ndingatenge nawo mbali?"
• "Kodi ndingapeze zotsatira zotani kuchokera ku mankhwala omwe alipo?"
• "Kodi zotsatirapo zake za chithandizo ndi ziti? Kodi zingatheke bwanji kuzilamulira?"

Pomaliza, zinthu zoti muzikumbukira...

Mesothelioma ya m'mimba ndi khansa yosowa koma yoopsa. Kukumana ndi asbestos kungakhale chifukwa chachikulu. Ngati muli ndi zizindikiro zomwe takambiranazi, ndikofunikira kupita kuchipatala nthawi yomweyo.

Ndizachibadwa kukhala ndi mantha komanso nkhawa mukadziwa za matenda ngati awa. Koma kumbukirani, simuli nokha. Muli ndi madokotala, abale, ndi anzanu oti akuthandizeni. Chofunika kwambiri ndikupeza chidziwitso choyenera, kulankhula momasuka ndi madokotala anu, ndikupeza chithandizo chabwino kwambiri kwa inu. Chithandizo chingathandize kukulitsa moyo wanu ndikukweza moyo wanu.

Mesothelioma ya m'mimba , khansa, khansa ya m'mimba, asbestos, peritoneum, mesothelioma, HIPEC, zizindikiro, chithandizo