Kodi inuyo kapena munthu wina amene mumamudziwa adakupatsani mankhwala a Tamoxifen ndi dokotala wanu chifukwa cha khansa ya m'mawere? Kapena mudapatsidwa mankhwalawo chifukwa muli pachiwopsezo chachikulu chotenga khansa? Ndizachilendo kumva mantha pang'ono, kufuna kudziwa zambiri, komanso kukhala ndi mafunso ambiri mukamva dzina la mankhwalawa. "Kodi mankhwalawa adzachiritsadi khansa? Kodi zotsatira zake ndi ziti?" Mwina mukudabwa. Chifukwa chake, lero tikambirana za Tamoxifen, zomwe imachita pathupi, komanso zomwe tiyenera kudziwa, mwachidule, ngati kuti tikulankhula ndi mnzanu.
Mwachidule, kodi Tamoxifen ndi chiyani?
Tamoxifen ndi mankhwala ofala kwambiri omwe amagwiritsidwa ntchito pochiza khansa ya m'mawere. Komabe, si mankhwala a mitundu yonse ya khansa ya m'mawere. Amaperekedwa makamaka kwa anthu omwe ali ndi khansa ya m'mawere yokhala ndi mahomoni .
Kodi zimenezi zikutanthauza chiyani? Taganizirani izi, maselo ena a khansa ya m'mawere ali ngati makanda anjala. Amafunika mahomoni awiri omwe matupi athu amapanga mwachibadwa kuti akule ndikufalikira. Ndi estrogen ndi progesterone . Chomwe mankhwala a tamoxifen amachita ndichakuti amaletsa maselo a khansa kupeza "chakudya" chomwe amafunikira, chomwe ndi hormone ya estrogen.
Kuphatikiza apo, madokotala amalimbikitsanso mankhwalawa kuti ateteze khansa kwa iwo omwe ali pachiwopsezo chachikulu chotenga khansa ya m'mawere (mwachitsanzo, ngati wina m'banjamo adadwalapo khansa, kapena ngati ali ndi kusintha kwa majini monga ``(BRCA)```).
Kodi ubwino waukulu wa chithandizo cha tamoxifen ndi wotani?
Mankhwalawa athandiza kupulumutsa miyoyo ya akazi mamiliyoni ambiri padziko lonse lapansi. Zina mwa zabwino zake zazikulu ndi izi:
- Kupewa kubwereranso kwa khansa: Chiwopsezo cha khansa kubwerera pambuyo pa opaleshoni, chemotherapy, kapena radiation therapy chimachepetsedwa ndi 30% mpaka 50%.
- Kuteteza bere lina: Kwa munthu amene ali ndi khansa m'bere limodzi, chiopsezo chotenga khansa m'bere lina lathanzi chimachepa ndi pafupifupi 50%.
- Kupewa khansa yolowa m'malo: Kwa munthu amene ali ndi khansa yoyambirira (Ductal Carcinoma in Situ kapena DCIS), yomwe imapezeka m'mitsempha ya mkaka wa m'mawere, imachepetsa chiopsezo chokhala khansa yolowa m'malo ndi pafupifupi 50%.
- Kulimbitsa mafupa: Mankhwalawa amathandizanso kupewa matenda a osteoporosis komanso kulimbitsa mafupa, omwe amatha kuchitika munthu akasiya kusamba.
- Kuchepetsa cholesterol: Kumathandizanso kuchepetsa kuchuluka kwa cholesterol yoyipa m'magazi.
Tiyeni tiphunzirenso za momwe tingamwere mankhwalawo ndi zotsatira zake.
Dokotala wanu nthawi zambiri amakuuzani kuti mumwe tamoxifen ngati piritsi (`Nolvadex®`) kapena ngati madzi (`Soltamox®`) nthawi yomweyo tsiku lililonse. Nthawi ya chithandizo ikhoza kukhala zaka 5 kapena 10. Izi zidzatsimikiziridwa ndi dokotala wanu kutengera matenda anu.
Monga mankhwala ena aliwonse, tamoxifen ingayambitse zotsatira zina zoyipa. Zambiri mwa izi sizowopsa, ndipo si aliyense amene amakumana nazo. Koma ndikofunikira kuzidziwa.
| Mtundu wa zotsatira zoyipa | Kufotokozera ndi zizindikiro |
|---|---|
| Zotsatira zoyipa zofala | |
| Zizindikiro zofanana ndi kusamba | Kutentha thupi, thukuta usiku, komanso kuuma kwa m'mimba. |
| Kulemera/kutupa | Anthu ena akhoza kunenepa kapena kutupa (edema) m'malo monga miyendo. |
| Kusamba kosakhazikika | Kusakhazikika kwa msambo kapena kutha kwathunthu kwa msambo. |
| Matenda ena ang'onoang'ono | Kutupa kwa miyendo, nseru, kutuluka magazi m'mimba, ziphuphu pakhungu, kutopa, mutu. Mwa amuna, vuto la kusowa maliseche limatha kuchitika. |
| Zoopsa zazikulu koma zosazolowereka zomwe zimafuna chithandizo chamankhwala mwachangu | |
| Magazi amaundana | Matenda monga magazi kuundana m'mitsempha ya miyendo (Deep Vein Thrombosis - DVT) kapena sitiroko. |
| Matenda a Cataract | Mavuto a maso monga kusawona bwino. |
| Khansa ya m'chiberekero | Pali chiopsezo chochepa kwambiri chotenga khansa ya endometrial. |
Zoopsa zazikuluzi sizichitika kawirikawiri, koma ndikofunikira kuzidziwa. Dokotala wanu akukupatsani mankhwala awa chifukwa ubwino wa mankhwalawo ndi woposa zoopsa zake.
Mukafunika kupita kwa dokotala nthawi yomweyo!
Ngati mukumwa tamoxifen ndipo mukukumana ndi zizindikiro zotsatirazi, uzani dokotala wanu nthawi yomweyo kapena pitani ku Dipatimenti Yothandizira Zadzidzidzi (ETU) ya chipatala mwamsanga.
- Kupweteka pachifuwa mwadzidzidzi kapena kupuma movutikira .
- Malungo .
- Zizindikiro za sitiroko zikuphatikizapo kulankhula movutikira , kusawona bwino , komanso dzanzi ladzidzidzi mbali imodzi ya mkono, mwendo, kapena nkhope .
- Kutupa kwambiri m'miyendo, m'mapazi, kapena m'mapazi .
- Kusanza kosalekeza.
Samalani ndi zinthu izi mukamamwa mankhwala.
Kodi ndingatenge mankhwalawa panthawi ya mimba?
Ayi. Ayi ndithu. Ngati mutenga mimba mukumwa tamoxifen, mwana wanu akhoza kukhala ndi zilema zazikulu zobadwa nazo. Chifukwa chake, muyenera kupewa kutenga mimba mukumwa mankhwalawa komanso kwa miyezi iwiri mutasiya kumwa mankhwalawa. Lankhulani ndi dokotala wanu za kugwiritsa ntchito njira yolerera yosakhala ya mahomoni (monga makondomu).
Kodi tamoxifen ndi chemotherapy?
Ayi. Izi ndi zinthu ziwiri zosiyana. Tamoxifen ndi mankhwala a mahomoni . Makamaka, ndi a gulu la mankhwala otchedwa ``Selective Estrogen Receptor Modulators - SERMs.`` Chemotherapy ndi mankhwala omwe amapha maselo omwe amagawanitsa mofulumira (maselo a khansa komanso maselo athanzi). Koma tamoxifen imangoyang'ana ntchito ya mahomoni.
Kodi pali zakudya kapena zakumwa zilizonse zomwe ndiyenera kupewa ndikamamwa mankhwalawa?
Inde. Zakudya ndi zakumwa zina zimatha kuchepetsa mphamvu ya tamoxifen, choncho ndi bwino kuzipewa.
- Chipatso champhesa
- Ma tangerines
- Chakumwa chilichonse chokhala ndi mowa
Uthenga Wopita Nawo Kunyumba
- Tamoxifen ndi mankhwala othandiza kwambiri komanso opulumutsa moyo a khansa ya m'mawere yomwe imadalira mahomoni.
- Ndikofunikira kumwa mankhwala anu monga momwe dokotala wanu wanenera, panthawi yoyenera, komanso nthawi yoyenera.
- Musamaope zotsatirapo zake, koma dziwani bwino. Dziwani bwino zizindikiro za magazi kuundana kapena sitiroko (kutupa m'miyendo, kupweteka pachifuwa, kulankhula movutikira). Ngati mukukumana ndi chilichonse mwa izi, funsani upangiri wa dokotala nthawi yomweyo.
- Musatenge mimba mukatenga mankhwalawa komanso kwa miyezi iwiri mutasiya kumwa. Lankhulani ndi dokotala wanu za kugwiritsa ntchito njira yotetezeka yolerera.
- Kambiranani momasuka ndi dokotala wanu za mafunso, mantha, kapena kukayikira kulikonse komwe mungakhale nako. Iwo ndi okonzeka nthawi zonse kukuthandizani.
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