Kodi muli ndi matenda a shuga amtundu wachiwiri? Kapena muli ndi vuto la mtima kapena mitsempha yamagazi? Ngati ndi choncho, dokotala wanu mwina adakupatsani mankhwala otchedwa Empagliflozin, omwe amadziwikanso kuti Jardiance. Mankhwalawa amaperekedwanso kwa anthu omwe alibe matenda a shuga koma ali ndi matenda enaake a mtima. Chifukwa chake, popeza awa ndi mankhwala omwe akuperekedwa kwa anthu ambiri tsopano, tiyeni tikambirane za izi mwatsatanetsatane lero, ngati kuti tikulankhula ndi mnzanu.
Kodi mankhwala awa a Empagliflozin (Jardiance) amagwira ntchito bwanji?
Izi zingamveke ngati zasayansi pang'ono, koma n'zosavuta kwambiri. Mankhwalawa ali m'gulu la mankhwala otchedwa SGLT2 inhibitors. Dzina lonse ndi Sodium-glucose co-transporter 2 inhibitor.
Chabwino, tsopano mwachidule, izi ndi zomwe zikuchitika:
Impso zathu zili ndi puloteni yotchedwa SGLT2. Ntchito yake ndi kuyamwa shuga (shuga) kuchokera m'magazi kubwerera m'thupi. Empagliflozin imaletsa puloteni iyi yotchedwa SGLT2. Kenako , impso siziyamwanso shuga wochuluka m'magazi kubwerera m'thupi, koma m'malo mwake zimautulutsa mu mkodzo. Zili ngati fyuluta yochotsa zinthu zosafunikira. Mwanjira imeneyi, kuchuluka kwa shuga wochuluka m'thupi kumayendetsedwa.
Mankhwalawa amachepetsanso kuyamwa kwa sodium (mchere) kuchokera ku impso kupita m'thupi. Izi zimachepetsa ntchito ya mtima. Ichi ndichifukwa chake mankhwalawa ndi othandiza kwambiri kwa anthu omwe ali ndi matenda a mtima.
Kodi muyenera kuyembekezera chiyani mukamagwiritsa ntchito mankhwalawa?
Empagliflozin ndi piritsi lomwe mumamwa kamodzi patsiku. Ndi bwino kutsatira nthawi yomweyo tsiku lililonse. Madokotala nthawi zambiri amakuuzani kuti mumwe m'mawa. Mutha kumwa ndi chakudya kapena ayi.
Mankhwalawa amapezeka m'mitundu iwiri: 10 milligrams (10 mg) ndi 25 milligrams (25 mg). Dokotala wanu angayambe kumwa mankhwala ochepetsa mlingo kenako n’kuwonjezera mlingo ngati pakufunika kutero.
Chochita ngati mwaiwala kumwa mapiritsi? Ngati mwaiwala kumwa mapiritsi, imwani mwamsanga mukangokumbukira. Koma ngati nthawi yanu yotsatira yayandikira, musamwe mapiritsi onse awiri omwe munaiwala ndi ena nthawi imodzi. Dumphani mapiritsi omwe munaiwala ndikumwa mapiritsi ena panthawi yomwe mwakonza.
Nthawi zina dokotala wanu angakupatseni mankhwalawa pamodzi ndi mankhwala ena a shuga. Mwachitsanzo, mungawamwe pamodzi ndi metformin (yotchedwa Synjardy) kapena ndi linagliptin (yotchedwa Glyxambi) ngati piritsi limodzi.
Kuti mupindule kwambiri ndi mankhwalawa, ndikofunikira kudya zakudya zabwino komanso kuchita masewera olimbitsa thupi nthawi zonse , monga momwe dokotala wanu akulangizira. Ndipo musaiwale kumwa madzi ambiri tsiku lonse.
Mukumwa mankhwalawa, dokotala wanu nthawi zina amayesa magazi kuti aone ngati impso zanu zikugwira ntchito bwino. Iyenso amakuuzani kuti muziyesa shuga m'magazi mwanu nthawi zonse. Zingatenge miyezi 6 kuti mankhwala awa agwire ntchito bwino.
Kodi zotsatirapo zake ndi ziti?
Monga mankhwala ena aliwonse, mankhwalawa akhoza kukhala ndi zotsatirapo zazing'ono. Koma musadandaule, zambiri mwa izo sizowopsa. Tiyeni tiwone zotsatirapo zake.
| Zotsatira zoyipa | Kufotokozera ndi choti muchite |
|---|---|
| Zotsatira Zofala | |
| Matenda a yisiti m'dera la maliseche | Zimapezeka kwambiri mwa akazi, koma zimathanso kuchitika mwa amuna. Zizindikiro zake ndi monga kuyabwa, kupweteka, kutupa, kufiira, ndi kutuluka magazi. Pali mankhwala a izi, choncho pitani kwa dokotala ngati muli ndi zizindikirozi. |
| Matenda a mkodzo (UTIs) | Zizindikiro monga kutentha, kupweteka, kukodza pafupipafupi, mkodzo wodzaza ndi mitambo, kapena magazi zingachitike. Kupweteka m'mimba kungachitikenso. Uzani dokotala wanu za izi chifukwa zimafunikanso chithandizo. |
| Zotsatira zina zazing'ono | Mungakhale ndi zinthu monga ludzu lochuluka, kukodza pafupipafupi, nseru, kupweteka kwa mafupa, ndi matenda a pakhosi. Izi nthawi zambiri zimatha pakapita nthawi pamene thupi lanu likusintha mankhwala. Ngati zipitirira, uzani dokotala wanu. |
| Zotsatirapo Zazikulu Zomwe Zimafunika Kusamalidwa Mwachangu | |
| Matenda aakulu a mkodzo | Malungo, kuzizira, kupweteka kwambiri m'mimba kapena msana. Izi zitha kukhala zizindikiro za matenda omwe amakhudza impso. Funsani dokotala nthawi yomweyo. |
| Kuthamanga kwa Magazi Kochepa | Chizungulire, mutu wopepuka, makamaka poyimirira. |
| Shuga wochepa m'magazi | Zizindikiro monga thukuta, kunjenjemera, kugunda kwa mtima kwambiri, njala, ndi kusokonezeka zimatha kuchitika, makamaka zikamwedwa limodzi ndi mankhwala ena a shuga. |
| Fournier's gangrene | Uwu ndi matenda osowa kwambiri komanso oopsa m'dera loberekera. Zizindikiro zake ndi monga kupweteka kwambiri m'derali, kutupa, kutentha thupi, komanso kutopa kwambiri. Izi ndi zadzidzidzi, pitani ku Dipatimenti Yoona za Zadzidzidzi (ETU) ya chipatala nthawi yomweyo. |
| Matenda a shuga a ketoacidosis | Matenda oopsa kwambiri omwe amayamba chifukwa cha shuga wambiri m'magazi. Zizindikiro zake ndi monga ludzu lochuluka, kukodza pafupipafupi, kupweteka m'mimba, nseru, kumva kufooka, komanso fungo la zipatso pamphuno. Izi ndi zadzidzidzi, pitani ku ETU nthawi yomweyo. |
| Matenda a ziwengo | Matuza pakhungu, kutupa kwa nkhope, milomo, kapena pakhosi, kuvutika kumeza kapena kupuma. Izi ndi zadzidzidzi, funani thandizo lachipatala nthawi yomweyo. |
Machenjezo ndi njira zodzitetezera zomwe muyenera kuzidziwa musanagwiritse ntchito
Musanayambe kumwa mankhwalawa, ndikofunikira kwambiri kuuza dokotala wanu za mankhwala onse omwe mukumwa (kuphatikizapo mankhwala a matenda ena, mavitamini, zowonjezera zakudya, ndi mankhwala achikhalidwe). Empagliflozin ingathe kuyanjana ndi mankhwala otsatirawa makamaka:
- Mankhwala ena a shuga
- Mankhwala oletsa kuthamanga kwa magazi monga ACE inhibitors ndi Angiotensin receptor blockers (ARBs)
- Mankhwala ochepetsa mphamvu ya mkodzo kapena "mapiritsi a madzi"
- Mankhwala opha ululu monga aspirin, ibuprofen, ndi naproxen
Dokotala wanu angafunike kusintha mlingo wa mankhwala ena omwe mukumwa kapena kusamala kwambiri ndi zotsatirapo zake.
Ngati muli ndi zizindikiro za ketoacidosis, dokotala wanu angakufunseninso kuti mufufuze magazi anu ngati muli ndi ma ketone. Pali zipangizo zapadera kapena mipiringidzo yoyesera mkodzo.
Musaiwale kumwa madzi ambiri , chifukwa mankhwalawa angayambitse kutaya madzi m'thupi.
Uzani dokotala wanu ngati mumamwa mowa, komanso ngati mumadwala matenda a yisiti kapena matenda a mkodzo pafupipafupi.
Ndani sayenera kumwa mankhwalawa?
Empagliflozin si yoyenera aliyense. Pali zochitika zina zomwe mankhwala awa sayenera kumwedwa:
- Ngati mukulandira dialysis ya impso.
- Ngati ndinu mayi woyamwitsa (mankhwalawa amatha kupita kwa mwana kudzera mu mkaka wa m'mawere).
- Ngati muli ndi pakati kapena mukukonzekera kutenga pakati (popeza zingavulaze mwana, lankhulani ndi dokotala wanu za izi).
- Ngati muli ndi vuto la empagliflozin kapena chilichonse mwa zinthu zomwe zili mmenemo.
Komanso, mankhwalawa savomerezedwa kwa anthu omwe ali ndi matenda a shuga a mtundu woyamba, chifukwa amatha kuwonjezera chiopsezo chawo cha Ketoacidosis.
Kodi Empagliflozin (Jardiance) ndi yothandiza bwanji?
Kugwira ntchito kwa mankhwalawa kwawonetsedwa bwino m'mayesero azachipatala. Mu kafukufuku wa miyezi 6 mwa akuluakulu omwe ali ndi matenda a shuga amtundu wachiwiri, Empagliflozin:
- Kusala kudya shuga m'magazi nthawi zambiri kumachepa ndi pafupifupi 19-25.
- Mtengo wa A1c, womwe umasonyeza kuchuluka kwa shuga m'magazi m'miyezi 2-3 yapitayi, watsika ndi 0.7% - 0.8%.
Kuphatikiza apo, anthu ena adachepetsanso thupi . Omwe adatenga mlingo wa 10mg patsiku adataya pafupifupi 2.5% ya kulemera kwa thupi lawo (mwachitsanzo, pafupifupi 2.25 kg kwa munthu wolemera makilogalamu 90). Omwe adatenga mlingo wa 25mg adataya 2.8% ya kulemera kwa thupi lawo (mwachitsanzo, pafupifupi 2.5 kg kwa munthu wolemera makilogalamu 90).
Pakhalanso kuchepa pang'ono kwa kuthamanga kwa magazi kwa systolic mwa anthu omwe adamwa mankhwalawa.
Uthenga Wopita Nawo Kunyumba
- Empagliflozin (Jardiance) ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda a shuga ndi matenda ena a mtima. Amathandiza impso kuchotsa shuga wochuluka m'thupi kudzera mu mkodzo.
- Imwani mankhwalawa monga momwe dokotala wanu wanenera, nthawi yomweyo tsiku lililonse. Ngati mwaphonya mlingo, musamwe milingo iwiri nthawi yomweyo nthawi ina.
- Matenda a mkodzo ndi yisiti yochokera ku ziwalo zoberekera ndi ofala kwambiri ndi mankhwalawa. Uzani dokotala wanu ngati mukukumana ndi zizindikiro izi.
- Imwani madzi ambiri tsiku lonse chifukwa mankhwalawa angayambitse kutaya madzi m'thupi.
- Ndikofunikira kudziwitsa dokotala wanu za mankhwala ena onse omwe mukumwa.
- Ngati mukupeza zizindikiro zazikulu monga ziwengo, kupuma movutikira, Fournier's gangrene, kapena ketoacidosis , pitani ku dipatimenti yadzidzidzi ya chipatala (ETU) nthawi yomweyo.
- Musasiye kumwa mankhwalawa popanda upangiri wa dokotala.
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