Ngati inu kapena munthu amene mumamudziwa ali ndi vuto la kuvutika maganizo, dokotala wanu mwina anakupatsani mankhwala osiyanasiyana. Ngakhale kuti mankhwala atsopano amagwiritsidwa ntchito masiku ano, nthawi zina mumayenera kugwiritsa ntchito mankhwala akale koma ofunika kwambiri. Anthu ena amapeza zotsatira kuchokera ku mankhwalawa. Lero, tikambirana za mankhwala ena akale koma osafunikira kwenikweni, tricyclic ndi tetracyclic antidepressants.
Kodi mankhwala oletsa kuvutika maganizo a tricyclic ndi tetracyclic ndi ati?
Mwachidule, awa ndi ena mwa mankhwala oyamba kupezeka kuti athetse kuvutika maganizo. Agwiritsidwa ntchito kuyambira m'ma 1950. Kusiyana pakati pa mayina awiriwa ndi kapangidwe ka mankhwala awo. Ma tricyclic ali ndi mphete zitatu (tri = zitatu) mu kapangidwe ka mankhwala awo, pomwe ma tetracyclic ali ndi mphete zinayi (tetra = zinayi). Koma onse amagwira ntchito m'thupi mofanana.
Madokotala samalimbikitsa kwambiri mankhwalawa masiku ano. Izi zili choncho chifukwa mankhwala atsopano monga SSRIs (Selective Serotonin Reuptake Inhibitors) abwera omwe alibe zotsatirapo zoyipa zambiri. Koma, taganizirani kuti mwayesa mankhwala atsopano angapo koma sizinagwire ntchito. Zikatero, dokotala wanu angakuyeseni imodzi mwa mankhwala akale awa.
Kodi mankhwala amenewa amakhudza bwanji ubongo?
Mu ubongo mwathu muli mankhwala apadera omwe amalamulira maganizo. Timawatcha ma neurotransmitters. Serotonin ndi norepinephrine ndi awiri mwa ma neurotransmitters akuluakulu. Mlingo wa izi ukhoza kukhala wochepa mu ubongo wa munthu amene ali ndi vuto la kuvutika maganizo.
Mankhwala oletsa kupanikizika a Tricyclic (TCAs) amagwira ntchito powonjezera kuchuluka kwa serotonin ndi norepinephrine muubongo. Komabe, chifukwa mankhwalawa amakhudzanso ma neurotransmitters ena, ali ndi chiopsezo chachikulu cha zotsatirapo zoyipa kuposa mankhwala atsopano monga SSRIs. Komanso, kumwa mopitirira muyeso ndi koopsa kwambiri.
| Mankhwala oletsa kuvutika maganizo otchedwa tricyclic antidepressants (TCAs) omwe amagwiritsidwa ntchito kwambiri |
|---|
| Amitriptyline |
| Amoxapine |
| Clomipramine |
| Desipramine |
| Doxepin |
| Imipramine |
| Nortriptyline |
| Protriptyline |
| Trimipramine |
Kodi zotsatirapo zake ndi ziti?
Monga tafotokozera kale, mankhwala awa ali ndi zotsatirapo zambiri. Ndicho chifukwa chake anthu ambiri safuna kuwagwiritsa ntchito. Koma si aliyense amene amalandira zotsatirapo zonsezi.
Chofunika kwambiri ndikulankhula ndi dokotala wanu za zotsatirapo zilizonse zomwe mumakumana nazo. Musasiye kumwa mankhwala mwadzidzidzi.
Nazi zina mwa zotsatira zoyipa zomwe zimachitika kawirikawiri:
- Kugona tulo
- Maso osawoneka bwino
- Kudzimbidwa
- Pakamwa pouma
- Kutsika kwa kuthamanga kwa magazi mukayimirira mwadzidzidzi kuchokera pamalo oyimirira (izi zingayambitse chizungulire)
- Kugunda kwa mtima kosakhazikika kapena kofulumira
- Kusokonezeka kwa okalamba, makamaka ngati atengedwa mlingo waukulu
- Kusakodza mokwanira (Kusunga mkodzo)
- Kuwonjezeka kwa chilakolako cha chakudya komanso kunenepa kwambiri
- Kutuluka thukuta
- Kugwedezeka
- Kugonana kapena kuchepa kwa chilakolako
- Anthu omwe ali ndi matenda a khunyu ali pachiwopsezo chachikulu cha khunyu .
Amitriptyline, Doxepin, Imipramine, ndi Trimipramine nthawi zambiri zimayambitsa kugona ndi kunenepa kwambiri. Komabe, Nortriptyline ndi Desipramine zili ndi zotsatirapo zochepa poyerekeza ndi zina.
Matenda ena ndi mankhwala a TCA
Ngati muli ndi vuto lililonse la matenda otsatirawa, muyenera kuuza dokotala wanu musanamwe mankhwalawa.
- Glaucoma
- Prostate yokulirapo
- Matenda a mtima
- Matenda a shuga
- Matenda a chiwindi
- Ngati mesentery idapangidwa kale
Ndipo inunsoNgati muli ndi pakati kapena mukukonzekera kutenga pakati, onetsetsani kuti mwalankhula ndi dokotala wanu.
Kuchuluka kwa mankhwala osokoneza bongo ndi zoopsa zake
Ichi ndi chinthu chofunikira kwambiri chomwe tiyenera kusamala nacho ndi mankhwala awa. Ngakhale kumwa mankhwala ochepetsa thupi pang'ono kungakhale koopsa kwambiri pa moyo. Chifukwa chake, madokotala nthawi zambiri amakayikira kupereka mankhwala awa kwa munthu amene akuganiza zodzipha. Ngakhale atatero, amawapatsa pang'ono kwambiri, monga kamodzi pa sabata.
| Zizindikiro za overdose ya TCA | |
|---|---|
| Kusakhazikika kwa kugunda kwa mtima | Kuthamanga kwa magazi pang'ono (Hypotension) |
| Kuuma kwambiri pakamwa | Kulephera kukodza |
| Kupuma pang'onopang'ono | Kunjenjemera ndi khunyu |
| Chikomokere | |
Chenjezo: Ngati mukukayikira kuti wina wamwa mankhwala ochulukirapo, ndi vuto lachipatala. Imbani 1990 Ambulance Service mwachangu, kapena pitani munthuyo ku chipatala chapafupi cha Emergency Department (ETU) nthawi yomweyo. Komanso, ngati n'kotheka, imbani National Poisons Information Centre ku Colombo National Hospital kuti mupeze upangiri. Mukapita kuchipatala, musaiwale kutchula dzina la mankhwala omwe munthuyo wamwa.
Kodi kusiya kumwa mankhwala mwadzidzidzi n’koopsa?
Inde, ndithudi. Kaya mukumva bwino kapena mukuvutika ndi zotsatirapo zake, musasiye kumwa mankhwalawa mwadzidzidzi popanda kufunsa dokotala wanu.Ngati mutero, mungavutike kwambiri chifukwa cha momwe thupi lanu limachitira ndi vutoli (zizindikiro zosiya kumwa mankhwala).
Izi sizikutanthauza kuti mwakhala mukuledzera ndi mankhwala osokoneza bongo. Mankhwalawa si oledzera. Koma thupi lanu ndi ubongo wanu zimazolowera mankhwala amenewo, kotero akatha mwadzidzidzi, zimatenga nthawi kuti thupi lizolowere.
Zizindikiro zomwe zingachitike mankhwala akasiyidwa
- Kukwiya, kukwiya
- Kusanza
- Kutuluka thukuta
- Kupweteka thupi, kumva kutentha thupi
- Kusowa tulo
- Thupi lopanda moyo
- Mutu
Choncho, ngati mukufuna kusiya kumwa mankhwalawo, muyenera kutero mwa kuchepetsa pang'onopang'ono mlingo, kutsatira malangizo a dokotala wanu .
Uthenga Wopita Nawo Kunyumba
- Mankhwala oletsa kuvutika maganizo otchedwa Tricyclic antidepressants (TCAs) ndi mankhwala akale ochizira kuvutika maganizo, koma ndi othandiza kwambiri kwa anthu ena.
- Mankhwalawa ali ndi chiopsezo chachikulu cha zotsatirapo zoyipa kuposa mankhwala atsopano. Lankhulani momasuka ndi dokotala wanu za izi.
- Ngati muli ndi matenda ena (monga matenda a mtima, glaucoma), onetsetsani kuti mwadziwitsa dokotala wanu musanamwe mankhwalawa.
- Musasiye kumwa mankhwalawa mwadzidzidzi popanda kufunsa dokotala wanu. Kuchita zimenezi kungayambitse kusasangalala m'thupi lanu.
- Kumwa mopitirira muyeso ndi koopsa kwambiri. Ndi vuto lachipatala. Ngati mukukayikira kuti izi zachitika, pitani kuchipatala nthawi yomweyo.
- Samalani thanzi lanu la maganizo. Lankhulani ndi dokotala wanu ngati muli ndi nkhawa iliyonse.
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