Kodi mwatopa ndi moyo chifukwa cha kuvutika maganizo? Tiyeni tikambirane za Ketamine (Ketamine yothandiza kuvutika maganizo)

Tangoganizirani munthu amene wakhala akuvutika ndi kuvutika maganizo kwambiri kwa zaka 25. Ayesa mankhwala ndi chithandizo chilichonse chomwe chilipo, koma palibe mpumulo. Atopa ndi moyo ndipo alibe chochita moti sangathenso kudzuka pa sofa. Kodi mungandikhulupirire nditakuuzani kuti mankhwala otchedwa 'Ketamine' awapatsa moyo watsopano? Izi ndi zomwe zachitikira anthu ena. Koma kumbuyo kwa nkhani iliyonse yopambana, timamvanso za anthu omwe ataya miyoyo yawo chifukwa chogwiritsa ntchito molakwika mankhwalawa. Ndiye, kodi Ketamine ndi chiyani kwenikweni? Kodi imathandiza ndi matenda amisala monga kuvutika maganizo? Kodi ndiyofunika kuiika pachiwopsezo? Tiyeni tikambirane za izi mosavuta komanso momveka bwino.

Kodi Ketamine ndi chiyani?

Mwachidule, Ketamine kwenikweni ndi mankhwala oletsa ululu. Ndiko kuti, mankhwala omwe amayambitsa kugona. Mankhwalawa, omwe adayamba kugwiritsidwa ntchito poletsa ululu ku nyama m'zaka za m'ma 1960, adavomerezedwa ndi US FDA kuti agwiritsidwe ntchito kwa anthu mu 1970. Anagwiritsidwanso ntchito pochiza asilikali omwe anavulala pa Nkhondo ya Vietnam.

Mwachitsanzo, pakagwa ngozi, akapulumutsa munthu amene akufuna kudzipha, nthawi zina mankhwala amenewa amaperekedwa mu ambulansi kuti achepetse kusokonezeka kwawo. Chifukwa cha zochitika ngati izi, madokotala anayamba kumvetsa mphamvu zake polimbana ndi kuvutika maganizo. Tangoganizirani, atapereka Ketamine kwa munthu amene anali pafupi kudumpha kuchokera pa mlatho ndikumupatsa mpumulo, patatha miyezi pafupifupi 9 akuti, "Sindinaganizepo zodzipha ndekha m'miyezi 9." Pamene nkhani zambiri ngati izi zikuchulukirachulukira, madokotala anaganiza kuti, "Mwina pali china chake pa izi."

Koma pali mbali yoipa pa izi. Ketamine ndi mankhwala omwe anthu ena amagwiritsa ntchito kuti aledzere. Ena amawatcha 'Special K', 'Super K'. Amabayidwa, amawonjezeredwa ku zakumwa, ndipo amagwiritsidwa ntchito mu ndudu.

Izi zimatenga pafupifupi maola awiri. Ziyenera kumwedwa pokhapokha ngati dokotala akuyang'anira. Izi zili choncho chifukwa zimakhala ndi zoopsa zazikulu monga kutaya chikumbumtima, kuthamanga kwa magazi, komanso kupuma pang'onopang'ono . Ngati zitagwiritsidwa ntchito molakwika, zingayambitse mavuto a nthawi yayitali monga mavuto a chikhodzodzo ndi kugwiritsa ntchito mankhwala osokoneza bongo.

Kodi ndingapeze bwanji chithandizo cha Ketamine?

Pakadali pano, mankhwala okhawo ochiritsira kuvutika maganizo omwe amavomerezedwa ndi FDA ndi mankhwala opopera m'mphuno opangidwa kuchokera ku ketamine otchedwa Esketamine. Amaperekedwa kokha kuchipatala chovomerezeka kwa anthu omwe ali ndi vuto lalikulu la kuvutika maganizo lomwe silingathe kulandira chithandizo ndipo sanalandire mankhwala ena osachepera awiri opopera maganizo. Wodwalayo akapatsidwa mankhwala opopera, amawunikidwa ndi ogwira ntchito zachipatala kwa maola awiri.

Njira zina, monga intravenous (IV) Ketamine, sizinavomerezedwe ndi FDA kuti zigwiritsidwe ntchito pochiza matenda amisala. Komabe, madokotala akugwiritsa ntchito njira imeneyi motsogozedwa ndi dokotala, kutengera zomwe zafufuzidwa, kwa anthu omwe sanalandire mankhwala ena.

• Chithandizo: Odwala nthawi zambiri amapatsidwa jekeseni zisanu ndi chimodzi m'mitsempha kwa milungu itatu.
• Mlingo: Mlingo uyenera kudziwika bwino, chifukwa pali mitundu yochepa kwambiri ya mlingo yomwe imagwira ntchito pochiza kuvutika maganizo koma osati pochiza ululu.
• Kuyang'aniridwa: Dokotala adzakhalapo kwa mphindi 40 zonse zoperekedwa ndi IV ndi kupitirira apo. Adzakhala okonzeka kuthandiza nthawi yomweyo ngati wodwalayo akumva kusasangalala kapena kusokonezeka.

Kodi zimamveka bwanji panthawi ya chithandizo?

Anthu omwe adalandira chithandizochi amafotokoza zomwe adakumana nazo m'njira zosiyanasiyana. Mayi wina dzina lake Krista, yemwe wakhala akuvutika ndi kuvutika maganizo ndi nkhawa kuyambira ali mwana, pambuyo pake adayamba kudwala PTSD komanso kupweteka kosatha. Iye akuti asanalandire chithandizo cha Ketamine, matenda amenewa ankalamulira moyo wake.

Jeff, munthu amene tinalankhula naye kale, anafotokoza zomwe zinamuchitikira motere: "Zinali ngati kuyandama m'dziwe la madzi. Umenewo unali nthawi yoyamba yomwe ndinamvetsa tanthauzo la mawu oti 'malo osangalatsa'. Chilichonse chokhudzana ndi moyo wanga weniweni chinatha, ndipo sindinamve kulemera komwe ndinali kunyamula kulikonse."

Pambuyo pa chithandizo, pamene zotsatira za Ketamine zikutha, zipatala zina zimaperekanso zokambirana ndi wodwalayo kuti zimuthandize kuphatikiza zomwe adaphunzira kuchokera ku zomwe adakumana nazo m'miyoyo yawo. Izi zimapatsa wodwalayo mwayi wokambirana za mavuto akale ndi ululu.

Kodi Ketamine imakhudza bwanji ubongo?

Chodabwitsa n'chakuti si 'zokumana nazo zodzipatula' zomwe mumakumana nazo panthawi ya chithandizo zomwe zimabweretsa mpumulo ku kuvutika maganizo. Mpumulo umenewo umabwera pambuyo pake. Izi zikutanthauza kuti, momwe ubongo wanu umayankhira mutamwa Ketamine ndiye chithandizo.

Tangoganizirani motere:

Kwa anthu omwe ali ndi vuto la kuvutika maganizo kwa nthawi yayitali, maulumikizidwe ena ofunikira (synapses) omwe amatumiza mauthenga pakati pa maselo amitsempha muubongo amatayika. Kafukufuku wapeza kuti mkati mwa maola 24 kuchokera pamene ketamine yatengedwa mlingo woyamba, maulumikizidwe amenewa amayamba kukulanso. Maulumikizidwe amenewa akamakula, mpumulo wa kuvutika maganizo umakula.

Mwanjira ina, maselo amitsempha muubongo mwathu omwe amakhudzidwa ndi malingaliro athu amagwiritsa ntchito mankhwala otchedwa ``glutamate`` kuti alankhulane. Anthu ena omwe ali ndi vuto la kuvutika maganizo ali ndi ma receptors ofooka muubongo mwawo omwe amayankha ``glutamate``. Ketamine imagwira ntchito pomanganso ma receptors awa ndikuthandiza maselo amitsempha kulankhulana bwino kachiwiri.

Pamene kulumikizana kwa ubongo kukukonzedwa motere, ngakhale mankhwala oletsa kuvutika maganizo kapena amisala omwe kale sankagwira ntchito angayambe kugwira ntchito.

Kodi zotsatirapo zake ndi zoopsa zake ndi ziti?

Ngakhale ikagwiritsidwa ntchito moyang'aniridwa ndi dokotala, Ketamine ikhoza kukhala ndi zotsatirapo zoyipa.

Chiwopsezo cha chizolowezi

Inde, Ketamine ndi mankhwala osokoneza bongo omwe angayambitse chizolowezi. Koma madokotala amati akalandira chithandizo motsogozedwa ndi dokotala komanso motsatira njira yoyenera, chiopsezo cha chizolowezi chimakhala chochepa kwambiri. Chiwopsezo chimabwera munthu akayamba kugwiritsa ntchito mankhwalawo pazifukwa zake popanda upangiri wa dokotala.

Kodi izi sizili zoyenera kwa ndani?

Chithandizo cha ketamine sichingakhale choyenera kwa anthu omwe akhala akugwiritsa ntchito mankhwala osokoneza bongo komanso matenda amisala monga schizophrenia. Anthu omwe ali ndi vuto la bipolar ayeneranso kusamala kwambiri, chifukwa Ketamine nthawi zambiri imayambitsa matenda amisala. Izi ziyenera kusankhidwa ndi dokotala wanu.