Kodi mukudziwa za matenda a Whipple? Tiyeni tikambirane za matendawa osowa kwambiri mwachidule!

Kodi nthawi zina mumamva ngati thupi lanu ndi lofooka kwambiri, muli ndi mavuto am'mimba, muli ndi ululu wa mafupa, koma simungapeze chifukwa chake? Mwina uwu ndi matenda omwe anthu ambiri sanamvepo, koma ndikofunikira kudziwa. Lero tikambirana za matenda osowa kwambiri, koma ngati atachiritsidwa bwino, omwe amachiritsidwa. Umenewo ndi matenda a Whipple.

Kodi matenda a Whipple ndi chiyani?

Mwachidule, matenda a Whipple ndi matenda osowa kwambiri a bakiteriya omwe amapezeka m'matumbo anu ang'onoang'ono . Izi zimachitika chifukwa chakudya chomwe mumadya sichikugayidwa bwino ndipo michere yomwe imafunikira siyikulowetsedwa m'thupi lanu (izi zimatchedwa "malabsorption"). Taganizirani izi, timadya chakudya kuti tipeze mphamvu ndi zakudya m'thupi lathu. Chifukwa chake ngati sichikulowetsedwa bwino, mavuto ambiri amatha kuchitika. Matendawa amapezeka pamene bakiteriya wotchedwa "Tropheryma whipplei" alowa m'thupi. Bakiteriya nthawi zambiri amapezeka m'nthaka, kutanthauza, m'nthaka. Koma nkhani yabwino ndi yakuti ndi "maantibayotiki" oyenera, mabakiteriyawa amatha kuchotsedwa m'thupi, kuchepetsa zizindikiro, ndikuchira kwathunthu .

Kodi matenda a Whipple ndi ofala bwanji?

Nayi mfundo yofunika. Ngakhale kuti mabakiteriya omwe amayambitsa matendawa ((Tropheryma whipplei)) ndi ambiri m'chilengedwe, makamaka m'nthaka, matenda a Whipple ndi osowa kwambiri . Malinga ndi ofufuza azachipatala, ngakhale m'dziko ngati America, akuti anthu pafupifupi asanu ndi anayi mwa miliyoni amadwala matendawa. Izi zikutanthauza kuti si aliyense amene ali ndi kachilomboka. Chifukwa chenicheni sichikudziwikabe.

Kodi zizindikiro za matenda a Whipple ndi ziti?

Zizindikiro za matenda a Whipple sizimaonekera mwadzidzidzi. Zimakula pang'onopang'ono m'magawo angapo .

Zizindikiro za gawo loyamba (Gawo la Prodromal)

Zimayamba ndi ululu waukulu wa mafupa . Ululuwu ukhoza kubwera ndi kutha. Umakhudza makamaka mafupa anu akuluakulu - akakolo, zigongono, chiuno, mawondo, ndi mapewa . Madokotala nthawi zina amatcha gawo loyambirira ili kuti "gawo la prodromal." Izi zimatha kukhala zaka zisanu ndi ziwiri kapena zisanu ndi zitatu , kenako zizindikiro zina zimayamba kuwonekera. Tangoganizirani momwe zimakhalira zovuta kukhala ndi ululu wa mafupa kwa zaka zambiri popanda kupeza chifukwa.

Zizindikiro zamtsogolo

Patapita nthawi, zizindikiro zotsatirazi zingawonekerenso:

• Kupweteka m'mimba: Sikuti ndi kupweteka m'mimba kokha, koma kungakhale kupweteka komwe kumakulirakulira mukadya kapena kosalekeza.
• Kutsegula m'mimba (ndowe zamadzi): Ndowe zamadzi zomwe zimachitika kangapo patsiku. Izi zingayambitse kusowa madzi m'thupi komanso kutayika kwa michere m'thupi.
• Kutupa (Edema): Mungaone kutupa, makamaka m'miyendo ndi m'mapazi. Ngati kumamveka ngati dimple mukakankhira ndi chala chanu, kungakhale kutupa.
• Kutopa pafupipafupi:Kaya mugone tulo totani, thupi lanu limakhala lopanda moyo ndipo simukufuna kuchita chilichonse.
• Malungo: Kumva kutentha popanda chifukwa.
• Kusintha kwa mtundu wa khungu: Malo ena, makamaka omwe amawotchedwa ndi dzuwa, amatha kukhala akuda kuposa masiku onse.
• Ma lymph nodes otupa: Matumbo ang'onoang'ono m'malo monga khosi, m'khwapa, ndi m'mimba.
• Kuchepetsa thupi mosadziwika: Kuchepetsa thupi popanda kudya zakudya zopatsa thanzi kapena kuchita masewera olimbitsa thupi.

Mavuto a Mitsempha Yapakati

Pakati pa 20% ndi 40% ya anthu omwe ali ndi matenda a Whipple amakhala ndi mavuto a mitsempha yapakati . Uwu ndi matenda owopsa kwambiri. Zizindikiro zake zingakhale monga:

• Mavuto a kusasinthasintha: Mumamva kusakhazikika mukamayenda ndipo simungathe kuyima molunjika.
• Kusokonezeka: Kutaya chidziwitso cha komwe muli, nthawi, komanso anthu omwe mumawadziwa.
• Kuvuta kumeza: Kumva ngati ukutsamwidwa mukamameza chakudya kapena chakumwa.
• Kutaya kukumbukira: Kuiwala ngakhale zochitika zaposachedwa.
• Kusintha kwa umunthu: Kumva ngati kuti sulinso munthu amene unali kale, kukwiya msanga, komanso kukwiya.
• Kukomoka: Kutaya mwadzidzidzi chidziwitso ndi kukomoka.
• Zovuta kulankhula: Kusalankhula bwino, kulephera kulankhula momveka bwino.

Kodi n’chiyani chimayambitsa matenda a Whipple?

Malinga ndi momwe madokotala amadziwira, matendawa amayamba chifukwa cha mtundu winawake wa mabakiteriya (Tropheryma whipplei) omwe amapezeka m'nthaka . Aliyense amene ali ndi mabakiteriya amenewa ali pachiwopsezo chotenga matenda. Komabe, monga tanenera kale, matenda a Whipple ndi osowa kwambiri. Chifukwa chake, sizikudziwikabe chifukwa chake anthu ena okha ndi omwe amadwala matendawa .

Komabe, kafukufuku wapeza kuti zinthu zotsatirazi zitha kuwonjezera chiopsezo chotenga matendawa :

• Zaka: Matenda a Whipple awonetsedwa kuti amakhudza kwambiri anthu azaka zapakati pa 65-84 , koma amathanso kuchitika kwa anthu azaka zocheperapo.
• Kukumana ndi nthaka kapena ziweto: Kafukufuku akusonyeza kuti anthu ogwira ntchito ndi nthaka kapena ziweto ali pachiwopsezo chachikulu chotenga matendawa. Makamaka, anthu omwe amalima, amalima, kapena amagwira ntchito ndi ziweto angakhale pachiwopsezo chachikulu. Muthanso kukhudzidwa ndi mabakiteriyawa mukabzala kanthu kakang'ono m'munda mwanu.
• Kusintha kwa majini:Pali mgwirizano pakati pa matenda a Whipple ndi jini yomwe imapanga puloteni `(IFR4)`. Puloteni iyi imathandiza maselo a chitetezo cha mthupi lathu, monga `(maselo a B)` ndi `(maselo a T)`, kukula. Yapezekanso kuti ikugwirizana ndi kusintha kwa majini `(HLA-B27)`. Izi ndi zakuya pang'ono, koma mwachidule, kusintha kwina m'majini athu kungatipangitse kukhala ndi vutoli.
• Chitetezo chamthupi chofooka: Ngati muli ndi matenda omwe amakhudza chitetezo chamthupi chanu (monga HIV), kapena ngati mumwa mankhwala oletsa chitetezo chamthupi (amenewa amaperekedwa pa matenda ena, nthawi zina pa zinthu monga nyamakazi, kapena mutaika chiwalo), muli pachiwopsezo chachikulu chotenga matendawa.

Kodi ndi mavuto otani omwe angayambitse matenda a Whipple?

Monga tanenera kale, matenda a Whipple amayamba chifukwa chakuti thupi silingathe kuyamwa bwino mafuta, chakudya, mavitamini, ndi michere ina kuchokera ku chakudya chomwe chimadutsa m'matumbo ang'onoang'ono. Ndi matenda omwe amakula pang'onopang'ono pakapita nthawi . Izi zikutanthauza kuti ngati sachiritsidwa, mavuto atsopano komanso aakulu azaumoyo angabuke.

Mavuto ngati awa akhoza kuchitika:

• Kuchepa kwa magazi m'thupi (kuchepa kwa maselo ofiira m'magazi): Izi zingayambitse kutopa kosalekeza, kufooka, komanso kufiira.
• Matenda amisala (kulephera kukumbukira ndi kugwira ntchito bwino kwa maganizo): Izi zitha kuchitika ngati dongosolo la mitsempha lakhudzidwa.
• Kung'ung'udza kwa mtima: Izi zitha kumveka dokotala akamakuyang'anani ndi stethoscope.
• Oculomasticatory myorhythmia: Ichi ndi chizindikiro chenicheni, pomwe maso ndi nsagwada zikuoneka kuti zikuyenda limodzi .
• Kutuluka kwa madzi m'thupi (Pleural effusion): Izi zingayambitse kupuma movutikira.
• Uveitis: Zizindikiro zake zingakhale kufiira, kupweteka, komanso kusawona bwino.

Chofunika kwambiri n'chakuti, ngati matenda a Whipple akhudza mitsempha yanu yapakati, akhoza kukupha. Choncho ndikofunikira kuonana ndi dokotala nthawi yomweyo ngati muli ndi zizindikiro.

Kodi madokotala amazindikira bwanji matenda a Whipple?

Mukapita kukaonana ndi dokotala, iye adzakupimitsani kaye. Kenako, adzakufunsani za mbiri yanu yachipatala , kuphatikizapo mavuto aliwonse azaumoyo omwe alipo kapena omwe adachitika kale. Angafunsenso za mankhwala aliwonse omwe mumamwa komanso ngati pali aliyense m'banja mwanu amene adakumanapo ndi vuto lililonse mwa izi. Kuphatikiza apo, angachite mayeso otsatirawa:

• Kuchuluka kwa Magazi Okwanira (CBC) : Izi zimayang'ana momwe maselo a m'magazi alili, ngati pali kuchepa kwa magazi m'thupi, komanso ngati pali zizindikiro za matenda.
• Endoscopy yapamwamba ya m'mimba yaying'ono: Mu izi, chubu chokhala ndi kamera kakang'ono chimayikidwa kudzera pakamwa ndikuyang'ana mkati mwa matumbo ang'onoang'ono. Mwanjira imeneyi, kusintha kulikonse komwe kulipo, zizindikiro za matenda, zitha kuwonedwa. Mudzagonedwa musanayambe izi, kuti musamve kupweteka kulikonse.
• Mayeso a Polymerase Chain Reaction (PCR) : Iyi ndi mayeso apadera omwe angathandize kudziwa ngati mabakiteriya (T. whipplei) alipo. Angachitike pa chidutswa cha minofu yotengedwa kuchokera ku biopsy kapena mwina pa madzi ena a m'thupi.
• Kufufuza m'matumbo ang'onoang'ono : Pa nthawi ya endoscopy, chidutswa chaching'ono cha minofu chimatengedwa kuchokera m'matumbo ang'onoang'ono ndikuwunikidwa pogwiritsa ntchito maikulosikopu. Izi nthawi zambiri zimagwiritsidwa ntchito kutsimikizira matenda a Whipple. Zingathe kuwona kusintha kwina m'matumbo komwe kumachitika chifukwa cha mabakiteriya.

Kodi matenda a Whipple amachiritsidwa bwanji?

Zimatenga nthawi kuti mabakiteriya omwe amayambitsa matenda a Whipple achotsedwe m'thupi. Chifukwa chake, chithandizo chimatenga nthawi yayitali. Koma ngati muli oleza mtima, mutha kupeza zotsatira zabwino.

Izi ndi zinthu zazikulu zomwe zimachitika ngati chithandizo:

• Mankhwala Opha Majeremusi : Chithandizo nthawi zambiri chimayamba ndi mankhwala opha majeremusi m'mitsempha (IV) kwa milungu iwiri kapena inayi . Izi nthawi zambiri zimachitika kuchipatala. Pambuyo pake, muyenera kumwa mankhwala opha majeremusi pakamwa kwa miyezi 12 yotsatira . Nthawi zina, mungafunike kumwa kwa nthawi yayitali, mpaka zaka ziwiri. Ndikofunikira kwambiri kumwa mankhwalawo monga momwe dokotala wanu wanenera.
• Kubwezeretsa madzi m'thupi : Ngati mwataya madzi m'thupi chifukwa cha kutsegula m'mimba, mungapatsidwe madzi m'mitsempha kuti muchepetse vutoli. Kapena, mungauzidwe kuti mumwe zakumwa zoledzeretsa (monga Jeevani) kuti mulowe m'malo mwa madzi ndi mchere zomwe zatayika.
• Mavitamini ndi zakudya zowonjezera : Dokotala wanu angakulangizeni kuti mutenge zakudya zowonjezera kuti mubwezeretse mavitamini ndi zakudya zomwe matumbo anu sangathe kuyamwa bwino (monga vitamini D, B12, ndi chitsulo). Nthawi zambiri matendawa amakula chifukwa cha kusowa zakudya m'thupi.

Kodi pali zotsatirapo zilizonse za mankhwalawa?

Inde, zotsatirapo zina zingachitike, makamaka ndi maantibayotiki. Koma izi sizichitika kwa aliyense, ndipo ngakhale zitachitika, nthawi zambiri sizimakhala zoopsa.

• Kutsegula m'mimba (kupweteka m'mimba)
• Chizungulire
• Kusanza ndi kusanza
• Kutupa pakhungu
• Matenda a yisiti (makamaka m'mimba mwa akazi)

Ngati chinthu chonga ichi chichitika, ndikofunikira kuuza dokotala wanu . Akhoza kusintha mankhwala kapena kukupatsani china kuti achepetse zotsatirapo zake.

Kodi munthu amene ali ndi matenda a Whipple amakumana ndi chiyani?

Monga anthu ambiri, inunsoMukangoyamba kulandira chithandizo, mudzayamba kumva mpumulo mwachangu. Kupweteka m'mimba ndi mafupa kudzachepa pang'onopang'ono. Komabe, zingatenge zaka ziwiri kuti matumbo anu ang'onoang'ono achire mokwanira. Chifukwa chake, ndikofunikira kukhala oleza mtima ndi chithandizo.

Nthawi zambiri , matenda a Whipple amachira kwathunthu ndi chithandizo . Komabe, nthawi zina matendawa amatha kubwereranso chithandizo chitatha. Ndicho chifukwa chake madokotala apitilizabe kukufufuzani.

Dokotala wanu adzakupemphani kuti mubwere kudzayezetsa magazi nthawi zonse kwa nthawi yayitali. Mwachitsanzo, mungapemphedwe kuti muyezedwe ndi upper endoscopy:

• Miyezi isanu ndi umodzi iliyonse pachaka choyamba cha chithandizo.
• Kamodzi pachaka kwa zaka zitatu zotsatira .
• Kenako kamodzi pa zaka zitatu zilizonse kwa moyo wanu wonse .

Izi zimachitika kuti muwone ngati matendawa abwereranso. Chifukwa chake, musaphonye maulendo obwerezabwereza monga momwe dokotala walangizira.

Kodi matenda a Whipple angapewedwe?

N'zovuta kunena zimenezo. Chifukwa mabakiteriya omwe amayambitsa matenda a Whipple ali paliponse m'chilengedwe chathu, makamaka m'nthaka . Komabe, si aliyense amene ali ndi matendawa amene amadwala matenda a Whipple.

Komabe, anthu omwe ali ndi chitetezo chamthupi chofooka kapena omwe akumwa mankhwala oletsa chitetezo chamthupi ali pachiwopsezo chachikulu chotenga matendawa. Ngati ndinu m'modzi mwa anthuwa, ndi bwino kuvala magolovesi nthawi iliyonse mukagwira ntchito ndi dothi kapena matope, komanso kusamba m'manja bwino mukamaliza ntchito . Samalani kwambiri ngati mukulima dimba kapena kugwira ntchito ndi ziweto.

Kodi ndimadzisamalira bwanji?

Chofunika kwambiri ndikumwa mankhwala opha tizilombo monga momwe dokotala wanenera, kwa nthawi yonse . Musaphonye tsiku limodzi, ndipo imwani mankhwalawo kwa nthawi yonse yomwe dokotala wakupatsani. Anthu ambiri amafunika kumwa mankhwala opha tizilombo kwa chaka chimodzi kuchokera pamene apezeka ndi matendawa. Anthu ena angafunike kumwa mankhwala opha tizilombo kwa moyo wawo wonse. Zimenezo zili m'manja mwa dokotala.

Mukakhala ndi matenda a Whipple, thupi lanu lingakhale likusowa zakudya zambiri zofunika . Ngakhale mutapeza mpumulo kuchokera ku chithandizo, ndi bwino kufunsa katswiri wazakudya kuti akuuzeni zomwe muyenera kudya ndi kumwa . Izi zidzakuthandizani kupeza zakudya zoyenera komanso kukhala ndi thupi labwino.

Ndiyenera kukaonananso ndi dokotala liti?

Ngati mukupitiriza kukhala ndi zizindikiro za matenda a Whipple mutayamba kulandira chithandizo, kapena ngati zizindikirozo zabwerera mwamsanga chithandizo chitatha (monga, ngati muli ndi ululu m'mimba kapena kupweteka kwa mafupa), onetsetsani kuti mwaonana ndi dokotala wanu. Musazengereze. Izi zitha kutanthauza kuti matendawa abwerera, kapena kuti pakhoza kukhala vuto lina.

N’chifukwa chiyani matenda amenewa amatchedwa “matenda a Whipples”?

Ndi bwino kudziwa izi. Matendawa ndi mabakiteriya omwe amachititsa matendawa adatchulidwa dzina la George H. Whipple, katswiri wa matenda omwe adafotokoza koyamba zizindikiro zake mu 1907. Ofufuza adapeza mabakiteriya omwe adayambitsa matendawa patatha zaka 80. Adatcha mabakiteriya kuti Tropheryma whipplei. Dzinali ndi kuphatikiza kwa mawu awiri achi Greek, "trophe" kutanthauza zakudya ndi "eryma" kutanthauza kutsekeka . Zimatanthauza kuti zimayambitsa kusamwa bwino kwa chakudya . Kodi si dzina loyenera?

Mabakiteriya ali paliponse pozungulira ife (ndi mkati mwa matupi athu). Kawirikawiri, mabakiteriya omwe timakumana nawo tsiku lililonse sativutitsa. Koma kachilombo ka bakiteriya kameneka, matenda a Whipple, ndi kosiyana pang'ono. Kamayamba chifukwa cha bakiteriya wamba yemwe amapezeka m'nthaka yotchedwa Tropheryma whipplei.

Mutha kudwala matenda a bakiteriya (T. whipplei) kuntchito kapena mukulima. Komabe, si aliyense amene ali ndi matendawa amene angadwale matenda a Whipple. Mwamwayi, matendawa nthawi zambiri amatha kuchiritsidwa ngati atapezeka msanga ndikuchiritsidwa bwino.

Zinthu zofunika kwambiri zomwe muyenera kukumbukira

Matenda a Whipple ndi matenda osowa kwambiri a bakiteriya , koma amatha kuchiritsidwa ngati atachiritsidwa bwino .

• Ngati zizindikiro monga kupweteka kwa mafupa, kuvutika m'mimba, kutsegula m'mimba, ndi kuchepa thupi zikupitirira, onetsetsani kuti mwaonana ndi dokotala. Musanyalanyaze izi.
• Chithandizo chimaphatikizapo kumwa maantibayotiki kwa nthawi yayitali . Ndikofunikira kwambiri kuwatsatira bwino.
• Ngati mukugwira ntchito ndi dothi, makamaka ngati chitetezo chanu cha mthupi chili chofooka, sambani m'manja mwanu bwino ndikugwiritsa ntchito magolovesi .
• Ngakhale matendawa atachira, ndikofunikira kupita kukayezetsa nthawi zonse ('kutsatira') monga momwe dokotala wanenera.

Musaope matendawa. Ndikofunikira kudziwa zambiri ndikupempha upangiri kwa dokotala. Simuli nokha, ndipo pali madokotala omwe angakuthandizeni ndi vuto lililonse. Ngati muli ndi kukayikira kulikonse, musazengereze kulankhula ndi dokotala.

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