Chii chinonzi DHT? Chinokanganisa sei muviri wako? (Dihydrotestosterone)

Wakambonzwa nezveDHT kana Dihydrotestosterone here? Pamwe hongu, pamwe kwete. Asi ichi chinhu chakakosha zvikuru kumuviri wedu, kunyanya kuhutano hwevarume. Saka, nhasi tichataura nezveDHT iyi nenzira iri nyore yaunogona kunzwisisa.

Chii chinonzi DHT (dihydrotestosterone)? Zvichitaurwa zviri nyore...

Zvichitaurwa zviri nyore, DHT ihormone yakakosha inobatsira kukudziridza hunhu hwepabonde hwevarume . Unoziva, mahormone akafanana nenhume diki dzinodzora mashandiro ese mumuviri wedu. DHT inhengo yeboka remahormone anonzi Androgen. Androgen izita rinopiwa mahormone anokonzera hunhu hwevarume.

Funga nezvazvo, DHT inotanga kushanda mumuviri wemurume kubva panguva yaanenge ari mudumbu. Zvadaro, basa reDHT rinochinja panguva dzakasiyana muhupenyu hwake. Kunyange zvazvo masayendisiti asina chokwadi chekuti DHT inokanganisa sei vakadzi, vanofunga kuti inogona kukanganisa kukura kwebvudzi pamuviri uye munzvimbo dzakavanzika.

Iyo androgen huru mumurume mukuru itestosterone . Inenge 10% ye testosterone iyi inoshandurwa kuita DHT zuva rega rega . Maitiro aya anoitika muganda rakatenderedza nhengo dzesikarudzi uye muprostate gland muvarume. Muvakadzi, izvi zvinoitika muganda. Zvinoitikawo munzvimbo dzakaita sechiropa chedu. Nekuti varume vane testosterone yakawanda mumiviri yavo, mazinga avo eDHT akakwirawo zvakanyanya.

Chii chaizvo chinoitwa neDHT kumiviri yedu?

DHT inoita zvinhu zvakasiyana pamatanho akasiyana ehupenyu hwemurume. Inonyanya kukosha panguva yekukura kwemwana ari mudumbu uye panguva yekuyaruka .

Zvisinei, kusiyana ne testosterone, DHT haina basa guru mukuchengetedza mashandiro emuviri kumurume mukuru. Pakukura, DHT inonyanya kuonekwa muzvirwere zvakaita sekukura kweprostate uye kurasikirwa nebvudzi revarume.

Basa reDHT panguva yekukura kwemwana

Paanenge ari mudumbu, nhengo dzepabonde dzemwana dzinokura sedzechirume kana dzechikadzi zvichienderana nemamiriro ezvinhu emahormone. Kana ari mukomana, DHT inoshanda nemamwe mahormone (kusanganisira testosterone ) kudzvinyirira kukura kwehunhu hwechikadzi uye kukurudzira kukura kwehunhu hwechirume .

DHT inokosha pakukura kwenhengo dzekunze dzemurume, nhengo yemurume nemachende, mumwana ari mudumbu. DHT inobatsirawo pakukura kweprostate gland.

DHT panguva yekuyaruka

Mukomana paanosvika pazera rekuyaruka, DHT inobatsira kuti nhengo yemurume nemachende zvikure zvakanyanya. Kwete izvozvo chete, asi DHT ndiyo inonyanya kukonzera zvinotevera:

• PachisoKukura ndebvu.
• Kukura kwebvudzi remuviri.
• Kukura kwebvudzi munzvimbo dzakavanzika.
• Kukura kweprostate.

Chii chinoitika kana huwandu hweDHT hukawedzera?

Mamwe matambudziko ehutano ane chekuita nekuwedzera kwehuwandu hweDHT. Ngatitarisei kuti ndeapi:

• Kusashanda zvakanaka kweProstatic Hyperplasia (BPH)
• Kenza yeprostate
• Androgenetic alopecia (kurasikirwa nebvudzi revarume )
• Polycystic Ovarian Syndrome (PCOS) (muvakadzi)

Benign Prostatic Hyperplasia (BPH) uye DHT

Benign Prostatic Hyperplasia (BPH) chirwere chinowanzoonekwa muvarume vane makore anopfuura makumi mashanu .

Gland rako reprostate rinogona kuburitsa DHT yakawanda. DHT iyi inosimudzira mashandiro akanaka egland reprostate, uye inowanzoita kuti gland reprostate rikure. BPH iyi inogona kukonzera matambudziko akadai sekuoma kwekuita weti uye kusagadzikana pabonde .

Kenza yeprostate neDHT

Vanhu vane kenza yeprostate vanowanzova nehuwandu hwakawanda hweDHT. Kenza yeprostate inogona kukonzerwa nekuwedzera kwekushanda kweDHT muprostate yako, pamwe chete nemamwe majini anochinja-chinja anoita kuti masero eprostate akure zvisingadzoreki.

Androgenetic alopecia (kurasikirwa nebvudzi) uye DHT

Kusanyatsooneka kwebvudzi ndiko kwatinowanzodaidza kuti mhanza yemurume . Mumamiriro ezvinhu aya, bvudzi rinodonha kubva pamusoro nepamberi pemusoro. Nekufamba kwenguva, ganda rebvudzi rinodzikira.

Chimwe chikonzero chekurasikirwa nebvudzi uku kuwedzera kwekushanda kweDHT muzvigadziko zvebvudzi rako. Kune zvimwe zvikonzero, zvakaita sekukanganiswa kwemajini. Kana huwandu hweDHT hukawedzera, zvigadziko zvebvudzi zvinoderera, kutenderera kwekukura kwebvudzi kunopfupika, uye pakupedzisira bvudzi rinodonha.

PCOS neDHT

Polycystic Ovarian Syndrome (PCOS) chirwere chinokanganisa vakadzi. Chinoitika kana mazai avo achigadzira mahormone akawanda e androgen, kusanganisira testosterone. Izvi zvinotungamira kuhuwandu hwakakwira hweDHT. Izvi zvinogona kukonzera zviratidzo zvakasiyana-siyana, zvinosanganisira kuenda kumwedzi kusina kurongeka, kukura kwebvudzi remuviri zvakanyanya (hirsutism), uye mapundu .

Chii chinoitika kana huwandu hweDHT hukadzikira?

Mamwe mamiriro ezvinhu ane chekuita nemazinga akaderera eDHT. Ngationei kuti chii:

• Kushaikwa kwe5-alpha reductase `(kushomeka kwe5-alpha reductase)`
• Testosterone yakaderera / hypogonadism yevarume

Kuderera kwehuwandu hweDHT pane hwakajairika kunonyanya kukanganisa varume. Vamwe vesainzi vanotenda kuti huwandu hwakaderera hweDHT muvasikana hunogona kunonoka kuyaruka.

Kushaikwa kwe5-alpha reductase uye DHT

5-alpha reductase ienzyme inobatsira kushandura testosterone kuita DHT. Kuchinja kwemajini kunokanganisa kugadzirwa kweenzyme iyi kunogona kukonzera kuti mazinga eDHT ave akaderera kana kuti asavepo. Izvi zvinonzi 5-alpha reductase deficiency. Ichi chirwere chinogarwa nhaka kubva kuvabereki kuenda kuvana (autosomal recessive pattern) .

Kushaikwa kwe5-alpha reductase kunokanganisa kukura pabonde kwevana vari mudumbu remurume (avo vane machromosomes eXY). Vana vechirume vanoberekwa nekushomeka uku vanowanzo ratidza hunhu hunotevera:

• Nhengo dzekunze dzenhengo dzesikarudzi hadzisati dzakura zvakakwana.
• Kuvapo kwemachende anoshanda mumuviri (asina kubuda).
• Dumbu reprostate diki kana kuti risiripo.

Zvakakosha: Muzviitiko zvakakomba zvekushaikwa kwe5-alpha reductase, vana vechirume vane majini ane machromosome eXY vanogona kunge vaine nhengo dzekunze dzevakadzi. Zvisinei, kuderedzwa kweDHT hakukanganisi kukura kwematende (vanogona kugadzira urume) uye nhengo dzemukati dzevakadzi. Izvi zvakasiyana nechirwere chinonzi Androgen Insensitivity Syndrome. Vanhu vane chirwere ichi vane nhengo dzevakadzi dzakajairwa uye testosterone yakajairika kana yakakwira, asi havana androgen receptors, saka havakure hunhu hwechipiri hwepabonde, uye havakwanisiwo kubereka.

Vakomana vane chirwere che5-alpha reductase deficiency havaiti bvudzi rechiso kana vasvika pazera rekuyaruka. Zvisinei, miviri yavo ichiri kugadzira testosterone, izvo zvinotungamira kune zvinhu zvakaita senzwi rakadzama, kukura kwetsandanyama, uye kukura kwenhengo yemurume.

Mazinga e testosterone akaderera uye DHT

Testosterone mumuviri wako ndiyo inoshanduka kuita DHT. Saka, kana testosterone yako yakaderera, DHT yako ichave yakadererawo pane yakajairwa. Rimwe zita re testosterone yakaderera nderekuti varume vane hypogonadism.

Kune mhando mbiri huru dze hypogonadism yevarume: yekare (inowanikwa pakuzvarwa kana kuti gare gare muhupenyu) uye inotanga kunonoka. Zvichienderana nezera rako, hypogonadism yevarume inogona kukonzera matambudziko akasiyana-siyana.

Ndinofanira kuona chiremba here nezvehuwandu hwangu hweDHT?

Kana muchifunga kuti imi kana mwana wenyu mungave nechirwere chinokonzerwa neDHT yakaderera kana yakakwira, iva nechokwadi chekutaura nachiremba.Zvadaro anogona kuita bvunzo dzinodiwa kana kukutumira kune mumwe munhu ane ruzivo nezvehurongwa hwe endocrine, akadai sa endocrinologist.

Dihydrotestosterone, kana kuti DHT, inokosha pakukura kwepabonde kwevarume. Asi kana huwandu hwayo hwakanyanya kukwira kana kuderera, inogona kukonzera matambudziko akadai sekusakura zvakanaka kwenhengo dzekunze dzemuviri, kukura kweprostate, uye kurasikirwa nebvudzi. Kana uine zvinokunetsa nezvehuwandu hweDHT yako, usazeza kutaura nachiremba wako. Vanogona kuita bvunzo uye kukurudzira kurapwa kunogona kukubatsira.

Zvinhu zvakakosha zvekurangarira kubva muchinyorwa chino (Mharidzo Yekuenda Kumba)

• DHT ihormone inonzi androgen inobatsira zvikuru pakugadzira hunhu hwepabonde hwevarume .
• DHT yakakosha pakukura kwenhengo dzepabonde dzevarume panguva yemwana ari mudumbu uye pakukura kwebvudzi rechiso nebvudzi remuviri panguva yekuyaruka.
• Kuwanda kweDHT kunogona kukonzera zvirwere zvakaita se benign prostatic hyperplasia (BPH), kenza yeprostate, kurasikirwa nebvudzi kuvarume, uye PCOS kuvakadzi.
• Kana huwandu hweDHT hwakaderera, zvirwere zvakaita sekushomeka kwe5-alpha reductase zvinogona kukanganisa kukura kwepabonde kwevarume.
• Kana muine kusava nechokwadi kana kunetseka nezvemazinga enyu eDHT, zvakanaka kutsvaga rubatsiro rwechiremba .

Ndinovimba wava kunzwisisa zviri nani nezve DHT. Kuziva zvinhu zvakaita seizvi kwakakosha zvikuru pahutano hwako!

DHT , dihydrotestosterone, mahormone, hutano hwevarume, testosterone, prostate, kurasikirwa nebvudzi, PCOS