Wakamboona here kuti mumwe munhu mumhuri mako, pamwe ambuya vako vaunoda, sekuru, kana mumwe wevabereki vako, ari kukanganwa zvese zvishoma nezvishoma? Unoona zvichikuomera here kuita zvinhu zvawaimboita zvakanaka, zvakaita sekurima bindu, kuita mabasa epamba, kana kutsvaga nzira yako? Uyu ndiwo mufananidzo unofunga vazhinji vedu patinonzwa izwi rekuti Alzheimer's Disease. Asi waizviziva here kuti kune marudzi akasiyana echirwere ichi? Hachibate munhu wese nenzira imwechete. Nhasi, tichataura nezvazvo.
Chii chaizvo chinonzi chirwere cheAlzheimer?
Tisati tataura nezvemhando idzi, ngatinzwisisei zviri nyore zvinoitika kuuropi muchirwere cheAlzheimer. Fungidzira kuti uropi hwedu inetwork inoshamisa yemabhiriyoni ema neuron, kana masero etsinga, anoshanda pamwe chete. Zvese zvatinofunga, zvatinoyeuka, uye zvatinodzidza zvinoitwa kuburikidza nekutaurirana pakati pemasero aya.
Muchirwere cheAlzheimer's, rudzi rweprotein inonzi amyloid beta peptides inotanga kuungana muuropi nenzira isingadiwe. Izvi zvinoungana kuti zvigadzire ma plaque uye tangles . Zvichitaurwa zviri nyore, zvakafanana nekuvharika kwehurongwa hwekutaurirana kweuropi. Izvi zvinokanganisa kutaurirana pakati pemasero etsinga, uye nekufamba kwenguva, masero iwayo anofa. Izvi zvinoguma nezviratidzo zvakaita sekurasikirwa nendangariro, kuvhiringidzika, uye kuoma kuita sarudzo.
Chinhu chakakosha ndechekuti kunyange zvazvo zviratidzo izvi zvichikura nekufamba kwenguva mumurwere wese ane Alzheimer, kutanga uye kumhanya kwechirwere kunogona kusiyana kubva pamunhu kusvika pamunhu. Izvi zvinokonzerwa nemarudzi akasiyana echirwere chatiri kutaura nezvacho.
Mhando mbiri huru dzechirwere cheAlzheimer's
Masayendisiti anopatsanura chirwere cheAlzheimer muzvikamu zviviri zvikuru, zvichienderana nezera iro chirwere chacho chinoonekwa. Ngatitarisei musiyano uripo pakati pezviviri izvi.
| Hunhu | Alzheimer's yekutanga | Alzheimer's inokurumidza kutanga |
|---|---|---|
| Zera rekutanga | Vari pasi pemakore makumi matanhatu nemashanu (kazhinji vari pakati pemakore makumi mana kusvika makumi mashanu) | Makore makumi matanhatu nemashanu zvichikwira |
| Kuwanda | Kashoma (anenge 5% yevarwere vese) | Mhando yakajairika |
| Ukama hwemajini | Kazhinji pane hukama hwakasimba hwemajini (zvikanganiso zviri mumachromosome 1, 14, uye 21) | Kubatana kwemajini hakuna kujeka. Kunogona kuitika kana kusaitika mumhuri. |
| Kuchinja kwehuropi | Mapundu akawanda muuropi uye kurasikirwa kwehuwandu hwehuropi kunoonekwa. | Kunyangwe kuchinja kweuropi kuchiitika, kunogona kunge kuri padanho rakaderera kana tichienzanisa nedzimwe mhando. |
| Zvimwe zviratidzo | Kukwenya kwetsandanyama nekugwinha (myoclonus) kwakajairika. | Hunhu uhwu hunowanzo kuve hushoma. |
| Njodzi dzakakosha | Vanhu vane Down syndrome vari panjodzi huru. | Kukwegura ndicho chinhu chikuru chinokonzera njodzi. |
Zvimwe zvishoma nezvechirwere cheAlzheimer's chisati chatanga
Fungidzira, ko kana munhu ari pamusoro pabasa rake, achirera vana vake, uye achipedza nguva yakawanda muhupenyu hwake, akatanga kuva nematambudziko ekurangarira pazera remakore angangoita makumi mana nemashanu? Ichi ndicho chikamu chinosuwisa zvikuru chechirwere cheAlzheimer chinotanga. Kunyangwe chisingawanzoitiki, chinotyisa zvikuru munhu nemhuri yake vanoonekwa vaine chirwere ichi.
Kukuvadzwa kweuropi muvarwere ava kunogona kukurumidza uye kwakakura. Uyewo, chirwere ichi chinowanzo kanganiswa nezvinhu zvine chekuita nemajini - kureva kuti, zvimwe zvinhu zvisina kunaka mumajini anogara nhaka kubva kuvabereki kuenda kuvana.
Chirwere cheAlzheimer chinotanga kunonoka - rudzi rwatinoziva tese
Uyu ndiwo rudzi rwatinowanzoona uye rwatinotaura nezvarwo patinotaura nezveAlzheimer's. Takaona vanasekuru vedu vachirasikirwa nendangariro dzavo zvishoma nezvishoma pavanenge vachikura. Ndizvozvo. Chikonzero chaicho chemajini cherudzi urwu hachisati chawanikwa. Kureva kuti, hazvigone kutaurwa kuti uchachiwana zvechokwadi kana amai vako kana baba vako vaine chirwere ichi. Zvisinei, kana mumwe munhu mumhuri yako aine chirwere ichi, vamwe vari panjodziwo. Asi zvinotendwa kuti zvinhu zvakawanda, zvakaita semajini, mararamiro, uye zvinhu zvakatikomberedza, zvinokanganisa izvi.
Chii chinonzi Familyal Alzheimer's Disease (FAD)?
Ichi chimwe chirwere cheAlzheimer's chakakosha, asi chisingawanzoitiki. FAD (Familial Alzheimer's Disease) imhando yechirwere cheAlzheimer's chakasimbiswa kuti chinokonzerwa nemajini chaiwo .
Zvichitaurwa zviri nyore, zvinoda zvizvarwa zviviri (semuenzaniso, sekuru nababa) kuti vave nechirwere ichi. Izvi zvinokanganisa vanhu vasingasviki 1% yevarwere vese vane Alzheimer's. Chinonyanya kukosha ndechekuti, vanhu vazhinji vane Alzheimer's vanotanga chirwere ichi vane rudzi urwu rweFAD. Kureva kuti, inopfuudzwa kuburikidza nemajini avo.
Ndingaitei kana ndisina chokwadi nezvemumwe munhu mumhuri mangu?
Kana uine kusava nechokwadi kana kutya nezvekurangarira mumwe munhu mumhuri yako, kunyanya mudiki, usazviregeredza.
- Chinhu chakanakisa chekuita nekukasika ndechekuona chiremba ane ruzivo. Zviri nani kana uchikwanisa kuona chiremba wetsinga.
- Chiremba anobvunza nezvezviratidzo uye nhoroondo yezveutano hwemhuri.
- Kuongororwa kwakati wandei kuchaitwa kuti kuonekwe kana paine zvimwe zvinokonzera kurasikirwa nendangariro (zvakadai sekushomeka kwemavhitamini, matambudziko ethyroid, kana kushushikana).
- Kana zvichidikanwa, vachakutumira zvinhu zvakaita se brain scans (CT/MRI).
Yeukai kuti kuongororwa kwechirwere nekukurumidza kunobatsira murwere nemhuri kuronga pachine nguva uye kuwana rutsigiro nekurapwa kwakakodzera. Saka musatya kutsvaga mazano echiremba.
Mharidzo Yekuenda Nayo Kumba
- Chirwere cheAlzheimer hachisi chirwere chimwe chete. Kune mhando mbiri huru: chirwere chinokurumidza, chinobata vanhu vari pasi pemakore makumi matanhatu nemashanu, uye chirwere chinononoka, chinobata vanhu vanopfuura makore makumi matanhatu nemashanu.
- Rudzi rwechirwere ichi runotanga kamwe chete, asi zviratidzo zvaro nekukuvara kweuropi zvakanyanya. Runowanzobatanidzwa nechirwere chemajini chinopfuudzwa nezvizvarwa.
- Rudzi rwechirwere runotanga kunonoka rwatinowanzoona rune chekuita nekukwegura. Hapana chikonzero chaicho chemajini chakawanikwa.
- Kana paine munhu mumhuri yako, kunyanya achiri mudiki, ari kuratidza zviratidzo zvekusagona kurangarira zvinhu, usazviregeredza wobva wataura nachiremba nekukasika.
- Kuziva nezvechirwere ichi uye kuzivikanwa kwacho nekukurumidza ndiyo nzira dzakanakisisa dzekubatsira murwere kurarama hupenyu hwakanaka.
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