Iwe kana mumwe munhu waunoziva akambozvimba kamwe kamwe muzvikamu zvemuviri wako, kunyanya kumeso kwako, miromo, rurimi, kana makumbo, pasina kurwadziwa here? Dzimwe nguva kuzvimba uku kunogona kutokonzera kuoma kwekufema. Tinowanzoti chirwere ichi Angioedema. Nhasi tiri kutaura nezve mushonga wekudzivirira kuzvimba unopiwa kudzivirira kuzvimba kunoitika muchirwere ichi. Unonzi C1 Inhibitor, mushonga wekudzivirira wevanhu.
Zvichitaurwa zviri nyore, chii chinonzi mushonga uyu wekudzivirira chirwere cheC1 Inhibitor?
C1 Inhibitor ipuroteni inogadzirwa mumuviri wedu wese. Inodzora mamwe maitiro emuviri wedu wekudzivirira chirwere. Zvisinei, kune vamwe vanhu, nekuda kwezvikonzero zvemajini (izvi zvinonzi Hereditary Angioedema) kana zvimwe zvikonzero, iyi C1 Inhibitor protein haigadzirwe mumuviri zvakakwana. Ndipo panoitika kuzvimba kamwe kamwe sezvambotaurwa.
Saka, mushonga uyu unoshanda kupa muviri puroteni yeC1 Inhibitor iyo iri kushaikwa. Mushonga uyu unonzi 'Munhu' nekuti unocheneswa kubva muropa remunhu uye unogadzirwa mushure mekuita kwakakosha. Mushonga uyu unowanikwa pamusika pasi pemazita emhando dzakadai seCinryze kana HAEGARDA.
Chinonyanya kukosha ndechekuti mushonga uyu unoshandiswa kudzivirira kurwiswa kwe angioedema.
Zvinhu zvaunofanira kuudza chiremba wako usati watora mushonga uyu
Chiremba wako asati akupe mushonga uyu, anofanira kuziva nhoroondo yako yese yehutano. Iva nechokwadi chekuvaudza kana uine chimwe chezvirwere zvinotevera:
- Matambudziko ekugwamba kweropa: Kana wakambova nedambudziko rekugwamba kweropa, senge kugwamba kweropa mutsinga iri mugumbo (DVT - Deep Vein Thrombosis) kana sitiroko.
- Kurwara: Kana uine allergy yekudzivirira C1 Inhibitor kana chero imwe mishonga, chikafu, kana mishonga yekuchengetedza.
- Kubata pamuviri: Kana uine pamuviri, uchiedza kubata pamuviri, kana kuti uchiyamwisa.
Zvichibva paruzivo urwu, chiremba wako achasarudza kana mushonga uyu wakakunakira uye kuti ungaupa sei.
Mushonga uyu ungashandiswa sei?
Mushonga uyu unopiwa nenzira mbiri.
1. Kuisira mushonga mutsinga: Nzira yekupa mushonga, wakaita sesaline, mutsinga.
2. Jekiseni pasi peganda: Jekiseni diki rinopihwa pasi peganda.
Mushonga uyu unowanzopihwa nenyanzvi yehutano kuchipatara kana kukiriniki. Zvisinei, mune dzimwe nguva, ungangoda kutora mushonga uyu kumba. Muchiitiko ichi, uchadzidziswa zvakakwana kuti ungagadzira sei mushonga uye kuti ungaubaya sei nemazvo . Zvakakosha zvikuru kutora mushonga panguva yakakodzera uye nechiyero chakakodzera, sezvakaudzwa nachiremba wako.
Kana uri kuishandisa kumba, fungawo nezveizvi.
Kana uchishandisa tsono nemasirinji kumba, usazvirasire mumarara mushure mekushandisa. Shandisa mudziyo wekuisa zvinhu zvinopinza. Kana usina, bvunza chiremba wako kuti ungawana sei. Izvi zvakakosha pakuchengetedza kwako, kwemhuri yako, uye nharaunda.
Migumisiro inogona kuitika yemushonga uyu
Kufanana nemushonga upi zvawo, uyu unogona kuva nemigumisiro yakaipa. Asi havasi vese vanoiwana. Ngatikamurai migumisiro iyi muzvikamu zviviri.
| Migumisiro yemushonga weC1 Inhibitor | |
|---|---|
| Migumisiro yakakomba inofanira kutaurwa kuna chiremba wako kana ETU nekukasika | |
| Kurwara kwakanyanya | Mapundu paganda, kuvaviwa, kuzvimba kwechiso, miromo kana rurimi, kuoma kufema. |
| Zviratidzo zvekugwamba kweropa | Marwadzo, kuzvimba uye kudziya kwegumbo (DVT), kuoma kufema, kurwadziwa muchipfuva. |
| Zviratidzo zveSitiroko | Kushaya simba kana kushaya simba kwechiso, ruoko, kana gumbo, kuvhiringidzika, kuoma kutaura kana kunzwisisa, kuoma kufamba, dzungu, kurasikirwa nepfungwa dzakanaka. |
| Zvimwe zviratidzo zvakakomba | Musoro wakakomba, kuchinja kwemaonero. |
| Migumisiro isingawanzova yakakomba, asi inofanira kutaurwa kuna chiremba kana ikaramba iripo | |
| Musoro | Izvi zvinowanzo konzera migumisiro yakaipa. |
Kana ukaona zvimwe zviratidzo zvisingawanzoitiki zvisina kutaurwa pane urongwa uhwu, ndapota zivisa chiremba wako nezvazvo zvakare.
Zvimwe zvinhu zvishoma zvekufunga nezvazvo
- Kudhakwa: Kana uchifunga kuti wadhakwa mushonga upi zvawo, fonera National Poisons Information Centre kuColombo National Hospital nekukasika, kana kuenda kuEmergency Treatment Unit (ETU) yechipatara chiri pedyo.
- Kana ukarasikirwa nedosi: Kana ukarasikirwa nedosi, inwa nekukurumidza sezvaunoyeuka. Zvisinei, kana yava nguva yekutora dosi yako inotevera, siya dosi yawakarasikirwa wotora dosi yako inotevera panguva yakatarwa. Usambofa watora dosi mbiri panguva imwe chete.
- Yakagadzirwa neropa revanhu: Sezvambotaurwa, mushonga uyu unogadzirwa neropa revanhu. Saka, pane mukana mudiki kwazvo, asi kwete zero, wekutapurirana hutachiona. Zvisinei, mushonga uyu unogadzirwa mushure mekucheneswa zvakanyanya uye kuongororwa. Kusvika parizvino, hapana hutachiona hwakataurwa. Taura nachiremba wako nezve chero mibvunzo yaungave nayo nezveizvi.
- Usagovane mushonga nevamwe: Mushonga uyu wakanyorerwa iwe chete. Usambogovane nevamwe.
Zvakakoshawo kuzivisa chiremba wako kana zviratidzo zvako zvikasavandudzika, kana kuti zvikawedzera kuipa.
Mharidzo Yekuenda Nayo Kumba
- C1 Inhibitor ijekiseni rakakosha rinopihwa kudzivirira kuzvimba kamwe kamwe kunokonzerwa neAngioedema.
- Usati watora mushonga uyu, udza chiremba wako nezveruzivo rwese rwehutano hwako, kunyanya matambudziko ekugwamba kweropa uye allergies.
- Paunenge uchishandisa mushonga uyu, ziva nezvemigumisiro yakaipa (kunyanya zviratidzo zvekugwamba kweropa kana sitiroko). Kana ukasangana nechimwe cheizvi, tsvaga rubatsiro rwechiremba nekukasika.
- Taura pachena nachiremba wako nezvemibvunzo kana zvinokunetsa nezvemushonga uyu. Usatya.
- Kana uchishandisa sirinji kumba, iva nechokwadi chekuti wairasa zvakanaka uye zvakachengeteka.
👩🏽⚕️ Mibvunzo yekuwedzera (Mibvunzo Inowanzo bvunzwa)
💬 Mapiritsi eDifenoxin neAtropine / Motofen anoshandiswa pai?
Uyu hausi mushonga waunogona kungotenga kubva ku pharmacy! Uyu musanganiswa wemishonga ine simba zvikuru iri muboka remishonga (Opioid antidiarrheal) iyo vanachiremba vanopa kuti vamise manyoka akanyanya kana kurutsa asingatsungiririki uye anogara achienderera mberi uye akaita semvura!
💬 Kana manyoka akanyanya, piritsi iri (Motofen) ringamisa sei manyoka nekukasika?
Kana uchibuda tsvina, ura hunofamba nekukurumidza uye hunosundira tsvina kunze. Mushonga weOpioid (Difenoxin) uri mumushonga uyu unoremadza tsandanyama dziri muura ne100% uye unononoka (Unoderedza kufamba kweGI). Zvadaro, kana tsvina iri muura, inonwisa mvura zvakanaka uye manyoka anomira ipapo ipapo. Atropine (Anticholinergic) inobatsirawo kuomesa kuyerera kwemate/mvura kubva muura.
💬 Sei paine ka atropine mupiritsi iri rekudzivirira manyoka? Ndeipi njodzi dziripo?
'Difenoxin' iri mune iyi mushonga wakaita seOpioid! Saka, kana ukanwa yakawanda yeiyi, unogona 'kudhakwa/kudhakwa' zvakanyanya. Kuti zvisadaro, 'Atropine' inowedzerwa sechirango kune avo vanonwa iyi pachivande! Kana ukanwa mapiritsi akawanda, iyi Atropine inokonzera muromo wakaoma zvakanyanya, kurova kwemoyo nekukurumidza, uye kuchengetedza weti (Anticholinergic toxicity). Zvakare, kana ikapihwa vana, vanogona kumira kufema (Respiratory depression) uye kutofa!
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