Muviri wako unoburitsa mvura yakaita seiyi here? Ngatitaurei nezve Capillary Leak Syndrome!

Wakambonzwa nezveCapillary Leak Syndrome here? Zita racho ringanzwika serakaoma. Asi muchidimbu, idambudziko apo chikamu cheropa chinonzi plasma, chinobuda mutsinga diki dzeropa dziri mumiviri yedu, chinonzi capillaries. Mvura iyi inobuda mutsandanyama dzedu, nyama, nhengo, uye maburi emuviri. Ichi chinogona kuva chirwere chakakomba, saka zvakakosha kuziva nezvazvo.

Chii chinonzi chirwere ichi chinonzi capillary leak syndrome?

Zvakanaka, ngatitsanangurei zvishoma. Fungidzira kuti muviri wako une system yemapombi emvura. Mapombi aya ndiwo tsinga dzedu dzeropa. Mapombi madiki akanaka kwazvo ari mune izvi anonzi ma capillaries. Aya ndiwo machubhu anoenda neokisijeni nezvinovaka muviri kunhengo dzese dzemuviri wedu. Saka, mu `(Capillary Leak Syndrome)`, chikamu cheropa chinoyerera, kureva plasma , chinobuda kuburikidza nema capillaries aya madiki. Zvakafanana nemvura inobuda kubva mupombi yemvura.

Kubuda kwemvura uku kunoita kuti mvura iungane munzvimbo dzakasiyana dzemuviri. Semuenzaniso, mvura iyi inogona kupinda mutsandanyama, munyama, munhengo dzakasiyana-siyana, kana munzvimbo (mumiviri) umo nhengo dziri.

Zviitiko zve `(Capillary Leak Syndrome)` izvi zvinogona kuitika kakawanda pagore, kana kamwe chete muhupenyu. Zvisinei, kana zvikarapwa nekukurumidza, BP yako inogona kudzikira kamwe kamwe, zvichikonzera kutadza kushanda kwenhengo dzemuviri uye dzimwe nguva kutofa. Saka ichi hachisi chinhu chekurerutsa.

Hapana mushonga wekusingaperi weizvi parizvino. Zvisinei, zvakakosha kutsvaga rubatsiro rwechiremba nekukurumidza kuti udzore zviratidzo. Dzimwe nguva, zvinokwanisika kudzivirira kurwiswa mune ramangwana nekuramba uchishandisa mishonga kana kugamuchira munyu.

Pane mhando dzeizvi here? Dzakasiyana sei?

Ehe, kune mhando mbiri huru dze `(Capillary Leak Syndrome)`. Ngationei kuti ndedzipi.

• Systemic Capillary Leak Syndrome: Inonziwo ``Primary Capillary Leak Syndrome'' kana ``Clarkson's disease'', iyi inyaya yekuti kurwiswa kunoitika kakawanda , kunyangwe mumunhu ane hutano hwakanaka.
• Chirwere Chekubuda Kweropa Mukati Meropa: Apa ndipo panoitika kurwiswa kamwe chete nekuda kwechimwe chirwere, mamiriro ezvinhu, kana mishonga.

Zvichitaurwa zviri nyore, chimwe chinhu chinogona kuitika nguva dzose, uye chimwe chinhu chinoitika kwenguva pfupi nekuda kwechimwe chikonzero.

Ndiani ane mukana mukuru wekuwana chirwere ichi?

"Systemic Capillary Leak Syndrome" chirwere chisingawanzoitiki.Vanhu vari pasi pe500 pasi rose vanonzi vane chirwere ichi. Chinonyanya kuitika kuvanhu vane makore epakati nepakati. Hazviwanzoitiki kuvana vadiki. Zvisinei, nekuti vanhu vane chirwere ichi dzimwe nguva vanoonekwa zvisirizvo sevari mune chimwe chirwere, huwandu chaihwo hwevanhu vane chirwere ichi hunogona kunge hwakakwira zvakanyanya.

Zvisinei, "Secondary Capillary Leak Syndrome" inogona kuitika kuvanhu vezera ripi zvaro. Zvimwe zvirwere, zvirwere, uye mishonga zvinogona kukonzera chirwere ichi.

Chii chinoitika kumuviri kana izvi zvikaitika? (Zvikamu zvitatu)

Zvinoitika mumuviri wedu panguva yekurwiswa uku kwe `(Capillary Leak Syndrome)` zvinogona kukamurwa kuita zvikamu zvitatu. Ngationei kuti chii.

Danho rekutanga: Zviratidzo zvisati zvaonekwa (Prodromal phase)

Iyi inguva yezuva rimwe chete kana maviri chirwere chisati chatanga. Munguva iyi, unogona kutanga kuona zvimwe zviratidzo.

• Kunzwa kuneta
• Nyota yemvura yakawanda
• Zvinhu zvakaita sekufuta kamwe kamwe zvinogona kuitika.

Chikamu chechipiri: Chikamu chekubuda kwemvura kana chekumutsiridza muviri

Apa ndipo panoitika kurwiswa chaiko. Chinoitika ndechekuti mvura nealbumin (rudzi rweprotein muropa) zvinobuda muropa rako zvichienda munzvimbo dziri pakati penyama dzako. Izvi zvinoderedza huwandu hweropa rinotakura okisijeni. Kumanikidzwa kweropa rako kunoderera, uye masero matsvuku eropa anoungana pamwe chete, zvichiita kuti ropa rako rive rakakora. Kubuda kwemvura uku kunokonzera kudzikira kwehuwandu hweropa, kunonzi hypovolemia .

Chikamu chechitatu: Mushure mekurwiswa `(Chikamu chemashure mekubuda kwemvura kana chikamu chekutora vanhu)`

Iyi ndiyo nguva mushure mekunge kurwiswa kwapera. Chinoitika ndechekuti capillaries dzako dzinotanga kunwa mvura nealbumin kubva munyama zvakare. Zvisinei, panguva iyi, muviri wako unogona kuunganidza mvura yakawandisa (fluid overload) . Nekuda kweizvozvo, muviri wako unogona kugadzira weti yakawandisa (polyuria) uye mapapu ako anogona kuzadza nemvura (pulmonary edema).

Funga nezvazvo, zvakaita sechipanji chinonwisa mvura. Kutanga, mvura yacho inobuda mumuviri, uye kana ikainwisa zvakare nekukurumidza, inonwisa zvakawanda kupfuura zvayaifanira kuita.

Chii chinokonzera izvi?

Ngationei zvino kuti chii chinogona kukonzera chirwere ichi chinonzi `(Capillary Leak Syndrome)`.

Zvinokonzera `(Systemic Capillary Leak Syndrome)`

Kutaura chokwadi, chikonzero chaicho cheSystemic Capillary Leak Syndrome hachisati chazivikanwa. Vaongorori vanotenda kuti zvinogona kunge zvichikonzerwa nemaitiro emasoja edu ekudzivirira chirwere kana hutachiona.

Zvinokonzera `(Secondary Capillary Leak Syndrome)`

Pane zvikonzero zvakawanda zveizvi. Chikonzero chinonyanya kukosha chirwere chinonzi sepsis . Kureva kuti, dambudziko rinouraya rinokonzerwa nehutachiona. Pamusoro pezvo, kune zvimwe zvikonzero:

• Zvirwere zve autoimmune:Chinoitika apa ndechekuti masoja edu ekudzivirira muviri anorwisa masero edu ane hutano.
• Differentiation syndrome: Dambudziko rinogona kuitika panguva yekurapwa kwemamwe marudzi e leukemia (acute promyelocytic leukemia kana acute myeloid leukemia).
• Engraftment syndrome: Dambudziko rinogona kuitika mushure mekuisirwa bota remapfupa.
• Hemophagocytic lymphohistiocytosis: Chirwere chinogona kuisa upenyu panjodzi chinokonzerwa nekushanda zvakanyanya kwemuviri wemuviri.
• Ovarian hyperstimulation syndrome: Dambudziko rinogona kuitika panguva yekurapwa kwekubereka.
• Kuchetura neRicin.
• Kurumwa nenyoka.
• Mafivha anobuda ropa nemavhairasi: Boka rezvirwere zvinotapukira zvinokonzerwa nemavhairasi.

Mimwe mishonga, yakaita semishonga inorwisa kenza inonzi gemcitabine (gemcitabine - Gemzar®) uye tagraxofusp (tagraxofusp - Elzonris®) , inogonawo kukonzera izvi (Secondary Capillary Leak Syndrome).

Ndezvipi zviratidzo zvinotangira chirwere ichi?

Kazhinji, zuva rimwe kana maviri usati wabatwa ne "Capillary Leak Syndrome", kureva kuti, panguva ye "prodromal phase", unogona kuona zviratidzo zvakaita se:

• Kurwadziwa kwemudumbu kana tsandanyama (myalgia).
• Kuneta zvakanyanya kana kushaya simba.
• Musoro .
• Nyota yemvura yakawedzera.
• Kutsamwa, hasha dzinokurumidza.
• Kusvotwa.
• Kuwedzera uremu kamwe kamwe.
• Zviratidzo zvehutachiona kana chirwere chemudumbu.

Kana ukaona zviratidzo zvakaita seizvi, usazvitore sezvisina basa, uchiti, "Aa, pamwe dzihwa chete," kunyanya kana wakambosangana nedambudziko rakafanana.

Ndezvipi zviratidzo zvinoonekwa kana uine chirwere?

Munguva yekurwiswa kwe `(Capillary Leak Syndrome)`, kureva kuti, panguva yekubuda kwechirwere ichi, zviratidzo zvinogona kusiyana kubva pamunhu kuenda kune mumwe. Zvisinei, zvinotevera ndizvo zviratidzo zvinowanzoonekwa:

• Kuzvimba, kunyanya mumakumbo (peripheral edema).
• Manyoka.
• Kuderera kweropa (hypotension).
• Kugwamba kweropa (hypercoagulability) - Izvi zvinogona kukonzerwa nekuwedzera kwehuwandu hwemasero matsvuku eropa (hematocrit) kana kuwedzera kwehuwandu hwemasero machena eropa (leukocytosis).

Vanachiremba vanoziva sei izvi?

Chiremba achaongorora chirwere cheCapillary Leak Syndrome nekubvunza nezvenhoroondo yako yehutano uye nekukuongorora muviri. Vachaongorora kana BP yako yakaderera.

Uyewo, vasati vasimbisa kuti iyi iCapillary Leak Syndrome, pane zvimwe zvirwere zvinofanira kubviswa. Vanogona kuita bvunzo dzeropa dzinoverengeka kuti vaite izvi:

• Tarisa kana ropa rako rakawanda (hematocrit ) (huwandu hwemasero matsvuku eropa muropa).
• Tarisa kana hemoglobin yakakwira (puroteni inowanikwa mumasero matsvuku eropa).
• Tarisa kana mapuroteni asina kusimba muropa (hypoalbuminemia).

Pamusoro pezvo, kuongororwa kweropa kunogona kuitwa kuti vaone kana paine protein yekudzivirira muviri isina kujairika inonzi ``monoclonal gammopathy, kana kuti M protein'' muropa. Vanhu vane ``Capillary Leak Syndrome'' vanogona kunge vaine iyi ``M protein'' isina kujairika muropa ravo.

Inorapwa sei? Inogona kurapwa here?

Zvinosuwisa kuti hapana mushonga usingaperi weCapillary Leak Syndrome. Vanachiremba vanoedza kudzora zviratidzo uye kudzivirira matambudziko.

Panguva yekurwiswa kwe "Capillary Leak Syndrome", vanachiremba vanoedza kudzora BP uye kuchengetedza kufamba kweropa kwakakodzera munhengo dzemuviri. Vanoedzawo kudzivirira kuzvimba kwakanyanya uye kuungana kwemvura. Vanogona kushandisa:

• Glucocorticoids: Aya ndiwo mhando ye steroid inobatsira kuderedza kubuda kwemvura kubva mutsinga dzeropa.
• Mvura inopinzwa mutsinga: Zvinhu zvakaita semunyu zvinopihwa kuti ropa riwedzere kufamba zvakanaka munhengo dzakadai seitsvo.

Kazhinji uchafanira kuendeswa kuchipatara mushure mekurwara. Munguva yekurapwa, chiremba wako acharamba achitarisa BP yako neBP yako kuti ave nechokwadi chekuti hauna mvura yakawandisa mumuviri wako, izvo zvinogona kukonzera mamwe matambudziko, akadai sekuputika kwemapapu uye kumira kwemwoyo kamwe kamwe.

Mushure mekurwiswa kweCapillary Leak Syndrome, inozivikanwa sechikamu chepost-leak kana kuti chikamu che recruitment, chiremba anogona kunyora mushonga we diuretic (mushonga unoita kuti ugadzire weti yakawanda) kuderedza huwandu hwemvura yakawandisa mumuviri wako.

Systemic Capillary Leak Syndrome (SCLS) inogona kudzivirirwa kuti isadzokorore here?

Haugone kudzivirira Systemic Capillary Leak Syndrome kuti isaitike pakutanga. Asi, kana wangobatwa nechirwere, unoziva kuti une chirwere chacho.

Zvisinei, kutora mishonga nguva dzose kana kugamuchira munyu kunogona kubatsira kudzivirira kurwiswa mune ramangwana uye kuderedza kuoma kwazvo. Mishonga iyi inogona kusanganisira:

• Kupihwa immunoglobulin (IVIG) pamwedzi.
• Mishonga inonwiwa yekurapa asima, yakaita se theophylline (theophylline - Elixophyllin®), terbutaline (terbutaline - Brethine®), uye montelukast (montelukast - Singulair®) .
• Deredza kuzvimbaMaSteroid.

Remangwana reavo vanorarama nechirwere ichi nderei? `(Outlook)`

Systemic Capillary Leak Syndrome inogona kurapwa nemishonga yekudzivirira. Kurapa kunobudirira kana chirwere ichi chikaonekwa nekukurumidza uye matambudziko acho ari mashoma. Mamwe ematambudziko akakomba anogona kuitika neCapillary Leak Syndrome anosanganisira:

• Chirwere chemukamuri: Kuwedzera kwekumanikidzwa mukati memhasuru uye kudzikira kweropa.
• Kuungana kwemvura yakakomberedza mwoyo nemapapu (cardiac tamponade, pericardial effusion, uye pleural effusion).
• Kukundikana kwemoyo.
• Kukundikana kweitsvo.
• Kurwara netsinga.
• Kuzvimba kwemapapu.
• Rhabdomyolysis: Kukundikana kweitsvo nekuda kwekukuvara kwetsandanyama.
• Kurohwa nechirwere.

Izvi zvinganzwika sekutyisa, asi sezvambotaurwa, kurapwa nekukurumidza uye kutarisirwa kwakakodzera kwakakosha zvikuru.

Ndinofanira kuona chiremba rini?

Kana uchifunga kuti uri kurwara neCapillary Leak Syndrome, enda kuna chiremba nekukasika. Vanogona kukubatsira kudzora zviratidzo zvako uye kukupa zororo.

Yeuka, kunyange zvazvo ichi chiri chirwere chisingawanzoitiki, zvakakosha kuziva zviratidzo uye kutsvaga rubatsiro rwechiremba nekukurumidza kana usina chokwadi.

Mharidzo Yekuenda Nayo Kumba

Zvakanaka, ngatidzokororei pfungwa dzakakosha dzatataura nezvadzo:

• Apa ndipo apo chikamu cheropa (plasma) chinobuda mutsinga diki dzeropa (capillaries) mumuviri wedu.
• Izvi zvinogona kuitika kamwe chete kana kakawanda.
• Kana zvikasarapwa, matambudziko akakomba anogona kuitika, saka rubatsiro rwechiremba nekukurumidza runokosha.
• Kunyange zvazvo pasina mushonga wechigarire, kune mishonga yekudzora zviratidzo uye kudzivirira kurwiswa mune ramangwana.
• Kana uchifungidzira chimwe chezviratidzo izvi, enda kuna chiremba nekukasika. Kana ukangoziva chirwere chacho nekukurumidza wotanga kurapwa, mikana yako yekupora inowedzera.

Saka, ndinovimba ruzivo urwu ruchakubatsira. Ramba uine hutano hwakanaka!

` Capillary Leak Syndrome, Kubuda Kweropa muPlasma, Kuderera Kweropa, Chirwere chaClarkson, Kubuda Kweropa, Kubuda Kwemvura Mumuviri