Zvakaoma kutaura kutya, kuzvidya mwoyo, uye kusava nechokwadi kunouya nekuonekwa uine kenza yemazamu. Asi chinhu chakakosha chaunofanira kuziva ndechekuti kurapwa kwekenza kwafambira mberi zvakanyanya nhasi. Nhasi, tichataura nezveimwe nzira itsva uye yepamusoro yekurapa. Inonzi Datroway. Ngationei kuti Datroway chii uye kana ichigona kukubatsira.
Mushonga werudzii Datroway? Unoshanda sei?
Zvichitaurwa zviri nyore, Datroway mushonga wakagadzirirwa uchishandisa tekinoroji yemazuva ano. Mukurapa, tinoudaidza kuti Antibody Drug Conjugate (ADC) . Funga nezvawo sevhisi yakakosha yekutumira mishonga. Molekyuri iyi yemushonga inoumbwa nezvikamu zvitatu zvikuru.
1. Antibody: Uyu ndiwo "muchina wekuwana kero" wemutumwa wedu. Unowana puroteni chaiyo (puroteni inonzi Trop-2) pamusoro pemasero ekenza uye unonamatira pairi. Basa rayo nderekuuraya nekubata masero ekenza chete, pasina kukuvadza masero ane hutano.
2. Mushonga wekurwisa kenza ( chemotherapy ): Uyu ndiwo "mushonga" uri mutsamba. Uyu ndiwo mushonga unoparadza masero ekenza.
3. Chinobatanidza: Chikamu ichi chinobatanidza antibody nemushonga wekurwisa kenza. Zviviri izvi zvinobatanidzwa pamwe chete pazvinenge zvichifamba muropa, uye zvobva zvaparadzaniswa mushure mekupinda musero rekenza.
Saka, kana mushonga weDatroway ukapinda mumuviri, antibody iri mauri inowana zvakananga masero ekenza uye inozvibatanidza. Zvadaro, chinongedzo ichocho chinotyoka, chichiburitsa mushonga wekurwisa kenza zvakananga mumasero ekenza. Nenzira iyi, sero rekenza rinoparadzwa mukati. Chinhu chikuru chekushandisa nzira iyi ndechekuti kukuvara kwemasero ane hutano kunoderedzwa zvakanyanya.
Kurapwa kweDatroway kunopiwa sei?
Datroway mushonga unopihwa muchipatara, kiriniki, kana nzvimbo yekurapwa uchitarisirwa nachiremba wako. Unopihwa semushonga wesaline kuburikidza netsinga (intravenous - IV infusion ) .
- Chipimo: Chipimo chemushonga chaunopihwa chinoenderana nehuremu hwemuviri wako.
- Purogiramu: Kurapwa uku kunowanzoitwa mavhiki matatu ega ega . Chiremba wako ndiye achasarudza kuti unoda kurapwa kangani.
- Kugadzirira: Usati wapihwa mushonga wemunyu, uchapihwa mimwe mishonga yekudzivirira kuda kurutsa, kurutsa, uye chero allergy inogona kuitika nekuda kwemunyu.
- Nguva yekurapwa:Kurapwa kwekutanga kunotora maminetsi angangoita makumi mapfumbamwe. Kana usina matambudziko makuru kekutanga, kurapwa kunotevera kunogona kuitwa mumaminitsi makumi matatu chete.
- Kuongororwa: Mushure mekurapwa kwekutanga kaviri, muchaongororwa nevashandi vezvehutano kweinenge awa imwe chete. Kana pasina matambudziko, muchaongororwa kwemaminitsi angangoita makumi matatu mumisangano inotevera mozobvumirwa kuenda kumba.
Ndingaziva sei kana kurapwa uku kwakandinakira?
Datroway haisi mushonga wemhando dzese dzekenza yemazamu . Chiremba wako anongokurudzira kurapwa uku chete kana kenza yako ichizadzisa zvinotevera:
- Kenza inofanira kunge iri hormone receptor-positive uye HER2-negative .
- Kana kenza isingabviswi zvachose nekuvhiyiwa (`isingabviswi`) kana kuti yapararira kune dzimwe nhengo dzemuviri (`metastatic`).
Chinhu chinonyanya kukosha ndechekuti kuti ukwanise kurapwa uku, unofanira kunge wakambogamuchira kurapwa kwakavakirwa pa endocrine uye kumwe kurapwa kwe chemotherapy.
Saka, sarudzo yakanakisisa yekuti kurapwa uku kwakakunakira here inotorwa nachiremba wekenza anokurapa . Iye achaongorora zvinyorwa zvako zvese zvehutano uye oita sarudzo iyi.
Migumisiro uye nzira yekuidzora nayo?
Kufanana nechero nzira yekurapa kenza, Datroway inogona kukonzera mimwe migumisiro yakaipa. Asi mashoko akanaka ndeekuti kune nzira dzekugadzirisa dzakawanda dzacho. Ngatitarisei migumisiro mikuru inogona kuitika uye zvaunogona kuita nezvazvo.
| Mhedzisiro yedivi | Maitiro ekutarisira |
|---|---|
| Matambudziko emaziso (Maziso akaoma, kutsvuka, kurwadziwa, kuona zvisipo) | Shandisa madonhwe emaziso anozora anokurudzirwa nachiremba wako kanenge kana kana pazuva. Dzivisa kupfeka magirazi ekuona panguva yekurapwa. Udza chiremba wako nekukasika kana ukaona shanduko kana kusagadzikana mumaziso ako. Ungangotumirwa kuna chiremba wemaziso. |
| Maronda emuromo | Chengeta chidimbu chechando kana mvura shoma yechando mumuromo mako uchipa mushonga wesaline. Shandisa mushonga wekuchenesa muromo wakanyorerwa nachiremba wako sezvakarairwa. Kana paine maronda emuromo akawedzera kana kuipa, zivisa chiremba wako nekukasika. |
| Kusvotwa nekurutsa | Inwa mushonga wekudzivirira kuda kurutsa wawakanyorerwa nachiremba wako panguva chaiyo, usati warapwa uye wapedza kurapwa. |
Aya ndiwo matambudziko anowanzo itika. Kana ukasangana nezvimwe zvinetso pamusoro peizvi, usatya kutaura nachiremba wako nezvazvo.
Ndezvipi zvinhu zvekunyatsoteerera?
Paunenge uchitora mushonga weDatroway, pane zvinhu zvishoma zvaunofanira kunyatsoteerera.
Matambudziko ane chekuita nemapapu
Kashoma, vamwe vanhu vanogona kuzvimba mapapu (`Interstitial Lung Disease` kana `Pneumonitis`) nekuda kwekurapwa uku. Saka, kana ukava nezviratidzo zvakaita sekukosora , kunetseka kufema, kufemereka, fivha, kana kusimba kwechipfuva , usazviregeredza uye zivisa chiremba wako nekukasika . Kana zvichidikanwa, chiremba achatanga kurapwa.
Kubata pamuviri uye kudzora pamuviri
Iyi inyaya yakakosha zvikuru.
- Kurapwa kweDatroway kunogona kukuvadza mwana asati aberekwa. Saka, uchaongororwa kuti uone kana une pamuviri usati watanga kurapwa.
- Kana uri mukadzi ane mukana wekubereka, unofanira kushandisa nzira yekudzivirira pamuviri inoshanda zvikuru panguva yekurapwa uye kwemwedzi minomwe mushure mekutora mushonga wekupedzisira .
- Kana uri murume uye mumwe wako achikwanisa kubata pamuviri, unofanira kushandisa nzira dzekudzivirira pamuviri dzinoshanda panguva yekurapwa uye kwemwedzi mina mushure mekutora mushonga wekupedzisira .
Kana muine mibvunzo nezvenyaya iyi, musazeza kutaura nachiremba wenyu.
Mharidzo Yekuenda Nayo Kumba
- Datroway mushonga wepamusoro-soro wekurapa mamwe marudzi ekenza yemazamu. Wakafanana ne "chikombora chinotungamirwa" chinotsvaga nekuparadza masero ekenza.
- Kurapa uku hakukodzeri munhu wese. Chiremba wekenza achasarudza kana kwakakunakira.
- Kurapa uku kunopihwa semvura ine munyu kuburikidza netsinga, kamwe chete pamavhiki matatu ega ega.
- Migumisiro yakadai sematambudziko emaziso, maronda emuromo, uye kuda kurutsa inogona kuitika. Asi izvi zvinogona kudzorwa. Udza chiremba wako nekukasika kana paine kusanzwa zvakanaka.
- Kana ukaona zviratidzo zvakaita sekuoma kwekufema, usazviregeredza. Tsvaga rubatsiro rwechiremba nekukasika.
- Zvakakosha kudzivirira kubata pamuviri panguva yekurapwa uye kwenguva yakati mushure mekurapwa.
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