Kana waonekwa kuti une kenza yemazamu, chiremba wako achaita bvunzo dzinoverengeka kuti adzidze zvakawanda nezvemasero ekenza. Izvi zvinowanzoitwa nekutora chidimbu chenyama yekenza kuburikidza nekuvhiyiwa kana biopsy. Imwe yedzo idzi ndeyekuona kana masero ekenza aine ' hormone receptors '. Funga nezvemareceptor aya se'locks' diki pamusoro pemasero. Kana 'makiyi' anonzi mahormone akapinda mumakiyi aya, masero anogamuchira meseji yekukura.
Progesterone ihormone inogadzirwa mumuviri wedu. Inokosha zvikuru pazvinhu zvakaita sekuyaruka, kuenda kumwedzi, uye pamuviri muvakadzi. Mamwe masero ekenza yemazamu ane mareceptor pamusoro pawo anogona kusungirirwa kuhormone iyi. Rudzi urwu rwekenza runonzi progesterone-receptor positive, kana kuti PR-positive (PR+) kenza yemazamu. Chinoitika munyaya iyi ndechekuti hormone progesterone inouya yosunga kumasero ekenza uye inoabatsira kukura zvakanyanya. Saka, kurapwa kweizvi kunoedza kumisa maitiro aya ehormone.
Imwe homoni inoshanda nenzira yakafanana iestrogen. Kana masero egomarara aine ma estrogen receptors, inonzi estrogen-receptor positive, kana kuti ER-positive (ER+) cancer.
Ndiani ari panjodzi huru yechirwere ichi?
Kana masero ako egomarara ari PR-positive, ER-positive, kana ese ari maviri, inowanzonzi hormone-receptor positive (HR+) kenza yemazamu. Nerombo rakanaka, kenza yemazamu inosvika 7 chete pa10 inoonekwa ndeyerudzi urwu. Kunyangwe rudzi urwu rwegomarara ruchigona kukura chero pazera ripi zvaro, runonyanya kuitika kuvakadzi vakambosvika panguva yekuguma kwemwedzi.
Kazhinji, zvinhu zvakafanana zvinokanganisa chero kenza yemazamu zvinokanganisawo kenza ine HR-positive. Ngationei kuti chii.
| Chinhu chine njodzi | Zvichitaurwa zviri nyore... |
|---|---|
| Kuva mukadzi | Vakadzi vari panjodzi huru kana tichienzanisa nevarume. |
| Kukwegura | Njodzi yacho inowedzera nekukura. |
| Zvisina kujairika mumasero emazamu | Kana wakambova nekukura kusina kujairika kwemasero muzamu (semuenzaniso LCIS ). |
| Nhoroondo yemhuri | Kana hama yepedyo yakamborwara nekenza yemazamu. |
| Kuyaruka kwepakutanga | Kuenda kumwedzi kunotanga usati wasvitsa makore gumi nemaviri. |
| Kuva nevana kunonoka | Kuva nemwana wekutanga mushure memakore makumi matatu nemashanu kana kusambobata pamuviri. |
| Kunonoka kuenda kumwedzi | Kusvika panguva yekuenda kumwedzi mushure memakore makumi mashanu nemashanu. |
| Kutora hormone therapy | Kutora mushonga wekutsiva mahormone mushure mekuguma kuenda kumwedzi. |
Zviratidzo zvacho ndezvipi?
Kazhinji, vakadzi vazhinji havaratidzi zviratidzo kana vaonekwa kuti vane kenza yemazamu. Asi, inowanikwa netsaona panguva yekuongororwa kwemazamu.
Zviratidzo zvegomarara rezamu rine HR-positive zvakafanana nezvemamwe marudzi egomarara rezamu . Heano mamwe ezviratidzo zvakajairika.
| Chiratidzo | Chengeta izvi. |
|---|---|
| Bundu idzva muzamu | Chero bundu idzva raunogona kunzwa, kunyangwe risingarwadzi. |
| Kuzvimba muzamu | Kuzvimba kwezamu rose kana chikamu charo. |
| Kurwadziwa kwemazamu kana mazamu | Kurwadziwa kusingawanzoitiki, kunoramba kuripo. |
| Kuchinja kweganda | Ganda rakanyura, ganda rakaita sereorenji, ganda rakakora, kutsvuka, kana kuti ganda rakaoma, rine makwapa. |
| Kuchinja kwemunyatso | Zamu rinopinda mukati kana kubuda kwemvura. |
| Manodhi elymph akazvimba | Mapundu ari muhapwa kana kutenderedza mutsipa anogona kubatwa muruoko. |
Kurapa kwehomoni kunoshandiswa sei?
Paunenge uchigadzira hurongwa hwekurapa kwako, chiremba wako achanyatso funga nezvemamiriro emahormone ekenza yako. Kurapa nemahormone ndiyo nzira huru uye inonyanya kukosha yekurapa kenza ine PR-positive. Chinangwa ndechekudzivirira masero ekenza kuti asashandise mahormone kukura.
Zvichitaurwa zviri nyore, kurapwa nemahormone kunobvisa kuwanikwa kwe'chikafu' (mahormone) chinodiwa nekenza.
Izvi zvinogona kuitwa nenzira mbiri huru:
- Kubviswa kwemazai ekubereka nepamuviri : Izvi zvinoderedza kugadzirwa kwemahormone mumuviri.
- Mapiritsi kana majekiseni ekurapa nehomoni: Mishonga iyi inodzivirira muviri kugadzira mahormone, kana kudzivirira ma receptors (kukiya) pamasero ekenza, zvichiadzivirira kuti asasungane nemahormone (makiyi).
Rudzi rwekurapwa kwemahormone rwaunowana runoenderanawo nekuti wakambosvika panguva yekuguma kuenda kumwedzi here. Kurapwa uku kunogona kushandiswa chero padanho regomarara. Zvichienderana nedanho regomarara, kurapwa kwemahormone kunopihwa pamwe chete nedzimwe nzira dzekurapa, dzakadai sekuvhiyiwa kana chemotherapy.
Ndezvipi zvimwe zvekurapa?
Pamusoro pekurapwa nemahormone, unogona kupihwa chimwe kana zvimwe zvezvinotevera zvekenza yemazamu ine PR-positive.
- Kuvhiya: Kuvhiya kubvisa masero egomarara. Semuenzaniso, kubvisa bundu chete (`Lumpectomy`) kana kubvisa zamu rose (`Mastectomy`).
- Chemotherapy: Mishonga ine simba inopihwa kuparadza masero ekenza.
- Kurapa nemwaranzi : Kunoshandisa mwaranzi ine simba guru kuparadza masero ekenza asara.
- Kurapa Kwakanangwa: Mishonga inonanga mapuroteni chaiwo anobatsira masero egomarara kukura. Izvi zvinogonawo kuwedzera kushanda kwemishonga yemahormone.
Chii chinonzi fungidziro?
Heano mamwe mashoko akanaka kwauri. Kenza dzine hormone-receptor-positive (HR+) dzinowanzo kukura zvishoma nezvishoma kupfuura hormone-receptor-negative (HR-Negative). Zvakare, une mukana wekurapwa nekuti dzinogona kuvharira kushanda kwemahormone uye kumisa kukura kwekenza. Zvisinei, sezvinoita chero kenza, mushonga weramangwana unoenderana nekuti unokurumidza kuonekwa sei.
Asi pane chimwe chinhu chekurangarira. Kunyange hazvo kurapwa nemahormone kuchigona kudzora kukura nekupararira kwegomarara, dzimwe nguva kunogona kuitika makore mushure mekurapwa. Ndosaka vanachiremba dzimwe nguva vachipa kurapwa nemahormone kwenguva yakareba, dzimwe nguva kwemakore mashanu kana gumi.
Saka, zvakakosha zvikuru kutaura pachena uye zvakajeka nachiremba wako nezvemamiriro e hormone receptor yegomarara rako uye kuti zvichakanganisa sei hurongwa hwako hwekurapwa uye mafambiro ekufamba kwenguva.
Mharidzo Yekuenda Nayo Kumba
- Kenza yemazamu inonzi PR-Positive (PR+) zvinoreva kuti masero ekenza anoshandisa hormone inonzi progesterone kukura.
- Rudzi urwu rwegomarara rwakajairika, kunyanya mushure mekuguma kwemwedzi.
- Kurapa nemahormone inzira inoshanda zvikuru uye huru yekurapa inoshandiswa pakuita izvi.
- Kufungidzira kuti chirwere ichi chingave chegomarara kwakanaka nekuti chinokura zvishoma nezvishoma, asi kurapwa kwenguva refu uye kuongororwa nguva nenguva zvinodiwa kuti chirwere chisadzokorore.
- Usambozeza kutaura nachiremba wako nezvechirwere chako, kurapwa kwako, uye chero zvinokunetsa.
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