Pane dambudziko here mutsinga dzeropa? Ngatidzidzei nezveEndothelial Dysfunction.

Wakambofunga here nezvekukosha kwetsinga dzeropa dziri mumiviri yedu? Dzakafanana nemigwagwa midiki inotakura mashoko nezvinovaka muviri mumiviri yedu yese. Saka chii chinoitika kana paine kusasimba mumutsara wakapfava mukati memigwagwa iyi, inonzi endothelium? Ndizvo zvatinodaidza kuti ``Endothelial Dysfunction''. Ngatitaurei nezvazvo zvishoma, zvakanaka?

Chii chinonzi Endothelial Dysfunction?

Zvichitaurwa zviri nyore, Endothelial Dysfunction inoitika kana masero matete ari mukati metsinga dzeropa anonzi endothelium asingashande nemazvo. Masero aya endothelial anowanzo batsira kuchengetedza mitsinga dzeropa dzakavhurika (dzakavhurika) kana zvichidikanwa. Asi kana kutadza kushanda zvakanaka uku kukaitika, zvinopesana zvinoitika. Kureva kuti, mitsinga dzeropa dzinotanga kukotama uye kutetepa.

Funga nezvazvo sepombi yemvura. Kana jira riri mukati mayo risina kunaka, zvichave zvakaoma kuti mvura ipfuure nepakati, handiti? Ndizvo zvazviri. Chikonzero chikuru chechirwere ichi chirwere chinonzi ``Vasospasm`` chine chekuita netsinga dzemwoyo. Muizvi, kunyangwe pasina chakavharwa mukati metsinga dzako dzemoyo,tsinga dzinongove dzakatetepa. Zvakare, ``Endothelial Dysfunction`` inowedzera njodzi ye``Atherosclerosis``, inova kuunganidzwa kwemafuta pamadziro etsinga uye kutetepa kwetsinga.

Saka basa re endothelium iyi nderei?

Tsinga dzese dzeropa dziri mumuviri wedu (idzo dzinoti tsinga dzeropa, tsinga dzeropa, capillaries) dzakazadzwa nemukati nechikamu chimwe chete chemasero chinonzi masero endothelial. Waizviziva here kuti endothelium iyi ndeimwe yenhengo huru mumuviri wedu!

Masero eEndothelial anoburitsa zvinhu zvakasiyana-siyana. Zvinhu izvi zvinodzora kuvhurwa nekuvharwa kwetsinga dzeropa (izvi zvinonzi ``Vascular Tone``). Iyi ``Vascular Tone`` inosarudza BP yedu, uye kuti mwoyo unoomerwa sei nekupomba ropa.

Kwete izvozvo chete, asi endothelium yako pachayo inoita mamwe mabasa akawanda akakosha:

• Inodzora mvura uye ma electrolytes muropa rako.
• Inobatsira kuumba ropa kana zvichidikanwa.
• Inodzivirira chepfu kuti isapinde munyama.
• Inodzora kuzvimba mumatishu.

Fungidzira kuti masero madiki aya anoshanda zvakadini mumuviri wedu!

Dambudziko iri rinonzi endothelial dysfunction rakajairika zvakadii?

Kwenguva yakareba, nyanzvi dzezvekurapa dzaifunga kuti endothelium yaingova chipingamupinyi chiri mukati metsinga dzeropa. Asi zvakazoonekwa kuti iyi inhengo inokoshawo. Ndipo panogona kuonekwa chirwere ichi chinonzi ``Endothelial Dysfunction`` sechirwere chakasiyana.

Zvakawanikwa izvi zvakaitwa kuma1990 ekupedzisira, zvichireva kuti chirwere ichi hachina kuzivikanwa kwenguva yakareba. Saka nyanzvi hadzisati dzakwanisa kutaura kuti chakapararira zvakadii pakati pevanhu.

Sei kusashanda zvakanaka kwe endothelial uku kuchiitika?

Chikonzero chikuru chechirwere ichi ndechekuti hapana gasi rakakwana rinonzi Nitric Oxide (NO) mukati memadziro etsinga dzeropa rako. Chinhu chinoshamisa ndechekuti, iyi nitric oxide inogadzirwa ne endothelium yako pachayo! Iyi nitric oxide i "(Vasodilator)", zvinoreva kuti inovhura tsinga dzeropa uye inobvumira ropa kuyerera zvakasununguka.

Saka, chii chinoitika kana huwandu hwe nitric oxide hukadzikira?

• Mitsipa yeropa inotetepa: Izvi zvinogona kukonzera kukwira kweropa.
• Kuzvimba kunoitika mumadziro etsinga: Izvi zvinogona kukonzera atherosclerosis, kana kuoma kwetsinga.
• Kugadzirwa kwemaplatelet kunowedzera: Izvi zvinogona kukonzera kuumbwa kweropa.
• Madziro etsinga dzeropa anova neburi: Izvi zvinoisa munyama mumasero eropa kune lipoproteins inokuvadza nedzimwe chepfu.

Ndezvipi zviratidzo zveEndothelial Dysfunction?

Chiratidzo chikuru chechirwere chemwoyo (endothelial dysfunction) iangina , inova kurwadziwa kwechipfuva. Kurwadziwa kwechipfuva uku kunoitika nekuti tsinga dzako dzinovhara panguva yadzinofanira kuvhurika. Kurwadziwa kwechipfuva uku kunowanzowedzera panguva yekurovedza muviri.

Vamwe vanhu vanogona kurwadziwa chipfuva nguva dzose (`Angina`) kunyangwe vasiri kuita chero chinhu. Izvi zvinogona kuva chiratidzo chekurwara nemoyo. Kana izvi zvikaitika, zviratidzo zvinosanganisira kurwadziwa chipfuva nguva dzose, kuneta zvakanyanya, uye kushaya mweya. Iyi idambudziko rehutano rinoda kurapwa nekukasika.

Ndiani ari panjodzi huru yeizvi? (Zvinhu Zvinokonzera Njodzi)

Zvimwe zvinhu zvinogona kuwedzera njodzi yako yekubatwa neEndothelial Dysfunction. Uri panjodzi huru kana uine zvinotevera:

• Chirwere cheshuga (`Diabetes Mellitus`)
• Kukwira kweropa (BP)
• Shuga yakakwira muropa (`Hyperglycemia`)
• Cholesterol Yakawanda
• Chirwere cheMetabolic
• Kusvuta
• Kufuta
• Zvimwe zvirwere zve autoimmune

Ndezvipi zvimwe zvirwere zvinogona kukonzerwa neEndothelial Dysfunction?

Dambudziko iri (Endothelial Dysfunction) rinowedzera njodzi yezvirwere zvemwoyo (Cardiovascular Diseases) nezvimwe zvirwere zvakawanda. Semuenzaniso:

• Atherosclerosis uye Coronary Artery Disease
• Kuvhara Maropa uye Kurohwa
• Mwoyo wakakura (Hypertrophic Cardiomyopathy)
• Kurwiswa neMwoyo uye Kukundikana kweMwoyo
• Kukwira kweropa (BP)
• Kukundikana kweitsvo
• Chirwere cheThyororo reMhino (PAD)
• Kukwira Kweropa Mumapapu (PH)
• Chirwere cheMidziyo Midiki (Chirwere cheMitsipa Midiki yeCoronary)

Ndezvipi zvinetso zvechirwere ichi?

Kusashanda zvakanaka kweEndothelial kunogona kukonzera chirwere chinonzi Acute Coronary Syndrome . Uku kusanganiswa kwemarudzi matatu echirwere chemwoyo. Izvi zvinowedzera njodzi yekuti mafuta arambe ari mutsinga yeropa abude. Kubuda kwakadaro kunogona kuvharira kufamba kweropa kuenda mutsandanyama yemwoyo uye kukonzera chirwere chemwoyo.

Chirwere ichi chinoonekwa sei ? (Kuongororwa)

Vanachiremba vanoshandisa bvunzo dzakasiyana-siyana dzemifananidzo kuti vaone zvakananga kuti ropa rinoyerera sei mutsinga dzeropa. Miedzo iyi inogona kubatsira chiremba kuona kana paine zviratidzo zvekushanda zvisina kunaka kwe endothelial. Miedzo iyi inosanganisira:

• Electrocardiogram (`Electrocardiogram - EKG`)
• Angiogram, kusanganisira Coronary Computed Tomography Angiogram (CCTA).

Uyewo, mimwe miedzo ye "Stress Imaging" inogona kushandiswa kuona kana kufamba kweropa mutsinga dzeropa kwaderera, izvo zvingave zvichikonzera kuti mwoyo wako ushande nesimba. Mienzaniso:

• Echocardiogram (`Echocardiogram - echo`)
• MRI (`MRI`)
• Positron Emission Tomography (PET scan)

Izvi zvinorapwa sei? (Kurapwa)

Kana uine chirwere chemwoyo kana cheperipheral artery (COPD) nekuda kwekusashanda zvakanaka kwe endothelial, chiremba wako anogona kukupa mimwe mishonga. Semuenzaniso:

• Aspirin kana mishonga inobvisa ropa.
• Mishonga inodzora BP, yakaita se calcium channel blockers.
• Mishonga inoderedza cholesterol yakaita se statins.
• Mishonga inovhura mitsipa yeropa, yakaita senitrates.

Uyewo, kana uine Endothelial Dysfunction, unogona kuderedza zviratidzo zvako nekuchinja zvekudya uye mararamiro . Izvi zvinosanganisira:

• Kudya chikafu chine hutano pamoyo uye kurovedza muviri nguva dzose.
• Kuderedza kunwa doro.
• Deredza huremu (kana zvichidikanwa) uye ramba uine huremu hwakanaka.
• Kutsvaga nzira dzakanaka dzekugadzirisa kushushikana .
• Tsvaga rubatsiro rwekurega kusvuta uye kudzivirira kusvuta fodya kubva kune vamwe vanhu.
• Kudzora zvakanaka zvirwere zvakaita seBP, chirwere cheshuga, uye cholesterol yakakwira.

Ndeipi tarisiro yevanhu vane Endothelial Dysfunction?

Dambudziko reEndothelial rinogona kurapwa nekuchinja mararamiro uye mishonga.Chirwere ichi chinorapika zvikuru. Zvisinei, vamwe vanhu vane chirwere chetsinga dzemwoyo chisingadziviriri (NOCAD) vanogona kuramba vachirwadziwa pachipfuva kunyangwe vachirapwa.

Rudzi urwu rwekurwadziwa kwechipfuva kwenguva refu runogona kukanganisa mabasa ezuva nezuva. Runogonawo kukonzera matambudziko akadai sekuzvidya mwoyo uye kuora mwoyo. Kurapa kwepfungwa, mishonga, uye nzira dzekugadzirisa kushushikana zvinogona kubatsira.

Ndinofanira kuona chiremba rini?

Kana ukaona zviratidzo zvinotevera, enda kuna chiremba nekukasika:

• Kurwadziwa kwechipfuva
• Kuoma kufema
• Zviratidzo zvechirwere chemwoyo (semuenzaniso, kurwadziwa kwakanyanya muchipfuva, kurwadziwa kunobva muruoko rweruboshwe, kurwadziwa mushaya, kudikitira, kuda kurutsa)
• Kuneta zvakanyanya pasina chikonzero

Chii chandinofanira kubvunza chiremba wangu?

Unogona kubvunza chiremba wako mibvunzo yakaita seiyi:

• Sei ndakava nechirwere ichi (Endothelial Dysfunction)?
• Ndinoda mushonga here?
• Ndedzipi shanduko dzemararamiro uye zvekudya zvandinofanira kuita?
• Ndiri panjodzi yekubatwa nechirwere chemwoyo here? Ndingaderedza sei njodzi iyoyo?
• Ndinofanira kuziva zviratidzo zvematambudziko here?

Mharidzo Yekuenda Nayo Kumba

Kusashanda zvakanaka kweEndothelial chirwere chemwoyo. Kana pasina nitric oxide yakakwana mumadziro etsinga dzeropa, tsinga dzinotetepa. Kutetepa uku kunoderedza kuyerera kweropa kuenda kumoyo. Chirwere ichi chinokonzera angina, kana kurwadziwa pachipfuva, uye kunowedzera njodzi yechirwere chemwoyo.

Chinhu chakanakisa ndechekuti, kana ukaona nekukurumidza uye ukawana kurapwa kwakakodzera, pamwe nekuchinja mararamiro ako, une mukana mukuru wekuzvidzivirira kubva kuzvirwere zvakakomba zvemwoyo. Saka, usaregeredza zviratidzo chero zvipi zvazvo. Kana usina chokwadi, kuchenjera kutsvaga mazano echiremba.

Kusashanda zvakanaka kweEndothelial , Chirwere cheMwoyo, Mitsipa yeRopa, Angina, Nitric Oxide, Kumanikidzwa kweRopa, Cholesterol