Zvese zvaunoda kuziva nezve kukosha kweALP muropa rako (Alkaline Phosphatase - ALP)

Wakamboongororwa ropa here, watora report, wakatarisa mavara nenhamba dziri pairi, wobva wafunga kuti, "Chii ichi?" Pakati pemavara akawanda akaita seALT, AST, neGGT, ungangove wakaonawo kukosha kunonzi "ALP." Vanhu vazhinji vanonetseka zvishoma pavanoona izvi. Saka, nhasi tichataura nezve Alkaline Phosphatase iyi, kana kuti ALP muchidimbu, chii chainotsvaga mubvunzo uyu, uye zvatinofanira kuziva kana kukosha kwayo kuchichinja.

Chii chaizvo chinonzi ALP?

Zvichitaurwa zviri nyore, Alkaline Phosphatase (ALP) ienzyme inowanikwa mumiviri yedu yese. Enzyme imhando yakakosha yeprotein inowanikwa mumasero edu. Kufanana nemuchina unomhanyisa mufekitori, maenzyme aya anobatsira nekukurumidzisa maitiro akasiyana-siyana emakemikari mumiviri yedu. Kune zviuru zvemaenzyme aya mumiviri yedu.

Kunyangwe vanachiremba vanga vachiongorora ALP kwemakore, havasati vaziva zvizere kuti basa rayo chairo nderei. Zvisinei, yakawanikwa iine chekuita nezvinhu zvakawanda zvakakosha mumuviri.

Kana tichitaura nezveALP, inowanzonzi "enzyme yechiropa." Chikonzero cheizvi ndechekuti ALP inowanikwa zvakanyanya muchiropa chedu. Asi haingogumiri pachiropa chete. Inowanikwawo mune dzimwe nzvimbo.

• Mapaipi enyongori yako: Machubhu anotakura nyongori inogadzirwa nechiropa kuenda nayo kunyongori, uko inochengetwa.
• Mumapfupa ako: Izvi zvinoreva kuti mumapfupa ako.
• Itsvo.
• Matumbu.
• Placenta yemadzimai ane pamuviri.

Saka, kana huwandu hweALP muropa rako hwakakwira zvakanyanya kana kuti hwakaderera, chiratidzo chekuti panogona kunge paine kukuvara kana shanduko mune imwe yenhengo idzi.

Chii chinonzi kuongororwa kweropa reALP?

Kuongororwa kweropa reALP kunoyera huwandu hweALP muropa rako. Sezvatakambotaura, kunyange zvazvo ALP ichiwanikwa mumuviri wese, manyuko maviri makuru eALP anoungana muropa chiropa nemapfupa. Saka, kana huwandu hweALP muropa hwakwira, zvinogona kuva chiratidzo chechirwere chechiropa kana chimwe chirwere chemapfupa. Asi yeuka, bvunzo yeALP yoga haigone kuona chirwere.

Kune mhando mbiri huru dzebvunzo dzeALP.

1. Bvunzo yeALP yenguva dzose: Iyi ndiyo bvunzo inowanzoitwa. Kazhinji, kana chiremba akakukumbira kuti uite `Comprehensive Metabolic Panel (CMP)` kana `Liver Panel (LFT)`, iyo inotarisa chiropa, zvechokwadi inosanganisira kukosha kweALP.

2. Kuedzwa kweALP isoenzyme:Iyi bvunzo yakakosha zvishoma. Kuongororwa kweALP nguva dzose kunokuudza chete kuti ALP yakawanda sei muropa rako. Asi bvunzo iyi ye isoenzyme inogona kukuudza chaizvo kana ALP yakawandisa muropa rako iri kubva muchiropa chako, mumapfupa, kana kune imwe nzvimbo. Kana huwandu hweALP yako hwakakwira zvakanyanya, chiremba wako anogona kuraira bvunzo iyi kuti awane chikonzero chaicho. Asi yakaoma zvishoma uye inodhura, saka havasi vese vanoongorora.

Sei tichida bvunzo iyi yeALP?

Panogona kunge paine zvikonzero zvakasiyana-siyana nei chiremba wako angaraira bvunzo yeALP.

• Kuongororwa: Dzimwe nguva, kunyangwe pasina zviratidzo, ALP inoongororwa sechikamu cheongororo yako yegore negore yeCMP kana LFT kuti uwane ruzivo nezvedambudziko riri muchiropa kana kune imwe nzvimbo zviratidzo zvisati zvaonekwa.
• Kuongororwa: Kana uchitova nechirwere chechiropa kana chemapfupa, bvunzo iyi inoshandiswawo kutarisa kana mamiriro acho ari kuvandudzika, ari kuramba akafanana, kana kuti ari kutowedzera kuipa nekurapwa.
• Sekubatsira pakuongorora chirwere: Kana uine zviratidzo zvine chekuita nechirwere chechiropa kana mapfupa, bvunzo yeALP chikamu chakakosha chekuongorora chirwere.

Zviratidzo zvinogona kuita kuti chiremba afunge nezvekuongororwa kweALP

Kana uine zviratidzo zviri pazasi, chiremba wako anogona kukutumira kuti uitwe bvunzo iyi.

Chii chinoitika ropa risati raongororwa uye panguva yekuongororwa?

Kana chiremba wako akakuudza kuti uite bvunzo iyi yeALP sechikamu cheCMP, uchafanirwa kutsanya kwemaawa angangoita 10-12. Asi unogona kunwa mvura. Zvisinei, kana ukakumbirwa kuti uongorore ropa, chiremba wako achakupa mirairo chaiyo yezvaunofanira kuita usati waongororwa. Zvakakosha kutevedzera mirairo iyoyo.

Izvi ndizvo zvinowanzoitika kana ropa ratorwa.

1. Uchagara pachigaro, uye mukoti kana chiremba achawana tsinga iri nyore muruoko rwako yekuburitsa ropa. Iyi inowanzova mukati megokora rako.

2. Mushure mekuwana tsinga, chenesa nzvimbo yacho zvakanaka nechinhu chakaita serubbing alcohol.

3. Zvadaro, tsono diki inopinzwa mutsinga uye ropa rinotorwa. Panguva iyi, unogona kunzwa kuruma kudiki, sekunge warumwa nesvosve diki.

4. Mushure mekuunganidza huwandu hweropa hunodiwa kuti uedze muchubhu, bvisa tsono wodzvanya nzvimbo yakatorwa ropa uchishandisa donje.

5. Kana ropa ramira kubuda, purasita diki inoiswa panzvimbo yacho uye basa rinopera.

Maitiro ese anotora maminetsi asingasviki mashanu. Panogona kunge paine kurwadziwa kudiki uye maronda painotorwa ropa. Asi izvozvo zvinopera mushure mezuva rimwe kana maviri.

Unonzwisisa sei zviri mumushumo?

Kazhinji unogona kuwana mushumo muzuva rimwe kana maviri. Mushumo wacho une ruzivo rwakadai seizvi:

• Zita rebvunzo (semuenzaniso Alkaline Phosphatase).
• Mhedzisiro yako (kukosha kweALP muropa rako).
• Nzvimbo yakajairika.
• Kunyangwe kukosha kwako kuri kwakajairika, kwakakwirira, kana kwakaderera.

Nhamba inogamuchirwa kazhinji i44 kusvika 147 mayuniti epasi rose pa litre (44 kusvika 147 IU/L). Zvisinei, mune dzimwe nzvimbo izvi zvinoonekwawo se30 kusvika 120 IU/L.

Uyewo, tsika dzeALP dzakajairika dzinosiyana zvichienderana nezera uye murume kana mukadzi.

• Vana nevechidiki: Vana nevechidiki vane huwandu hweALP hwakakwira nekuda kwekuti mapfupa avo ari kukura.
• Pakati pemakore gumi nemashanu kusvika makumi mashanu: Varume vane ALP yakakwira zvishoma pane vakadzi.
• Nekukwegura: mazinga eALP anokwira zvishoma zvakare sezvatinokura.
• Munguva yekuzvitakura: Zvakajairika kuti vanaamai vane pamuviri vave nemazinga akakwira eALP nekuti ALP inogadzirwa muplacenta.
• Kana pfupa rakatyoka ropora: Kana pfupa rakatyoka robva rakura zvakare, mazinga eALP anogona kuwedzera sezvo masero emapfupa anotanga kushanda.

Kuwanda kweALP kunorevei?

Kana huwandu hweALP yako hwakakwira, zvakajairika kuti unzwe kunetseka zvishoma. Zvisinei, chinhu chekutanga chekuyeuka ndechekuti huwandu hweALP hwakakwira zvishoma hachisi chiratidzo chechirwere chakakomba nguva dzose. Chiremba wako anogona kusarudza kusaita imwe bvunzo uye kungotarisa huwandu hweALP yako zvakare munguva pfupi.

Zvisinei, huwandu hweALP hwakanyanya kukwira chiratidzo chakasimba chekukuvadzwa kwechiropa kana chirwere chemapfupa. Kana gwaro rako rikati ALP yakakwira, chiremba wako anogona kuraira mimwe miedzo (semuenzaniso, bvunzo dze isoenzyme, kuskena kwechiropa) kuti awane chikonzero.

Zvikonzero zvikuru nei ALP ichigona kuwedzera zvinogona kukamurwa kuita mapoka maviri.

Zvikonzero zvine chekuita nechiropa ne biliary ducts

• Kuora kwechiropa panguva yekuzvitakura: Kurwara kwechiropa kunogona kuitika panguva yekupedzisira yekuzvitakura.
• Kurwara kwechiropa: Kukuvara kwechiropa zvachose kunoitika kana masero echiropa akafa uye anotsiviwa nemavanga.
• Chiropa: Kuzvimba kwechiropa. Izvi zvinogona kukonzerwa nemavhairasi, doro, kana zvimwe zvikonzero.
• Kuvharika kwenzira yekubvisa bile: Kuvharika kwenzira yekubvisa bile kubva muchiropa nekuda kwematombo emudumbu, bundu rekenza, kana zvimwe zvikonzero.
• Mononucleosis: Inozivikanwawo se "chirwere chekutsvoda," hutachiona uhu hunogona dzimwe nguva kukonzera kuzvimba kwechiropa.

Zvikonzero zvine chekuita nemapfupa (skeletal)

• Chirwere chePaget chepfupa: Chirwere chisingawanzoitiki apo mapfupa anoputsika uye anokurazve zvisina kujairika.
• Osteogenic sarcoma: Rudzi rwegomarara rinotanga mumapfupa.
• Kupararira kwemapfupa: Kenza inobva kune imwe nzvimbo, senge zamu kana mapapu, inopararira ichienda kumapfupa.
• Hyperparathyroidism: Kuwedzera kwecalcium muropa nekuda kwekubudiswa kwakanyanya kwemahormone neparathyroid gland.
• Hyperthyroidism: Kugadzirwa kwakanyanya kwemahormone negland regland.
• Osteomalacia: Chirwere chekuti mapfupa anoshaya simba uye anotyoka nyore nyore nekuda kwekushaikwa kwevhitamini D. Kana izvi zvikaitika kuvana, tinozvidaidza kuti Rickets.
• Kutyoka kunoporesa.

Ndezvipi zvikonzero zvingangoita kuti ALP ive yakaderera?

Kashoma kuti mazinga eALP ave akaderera zvakanyanya, asi pane zvikonzero zvakawanda zvinogona kukonzera izvi.

• Kushaya chikafu chakakwana: Kusawana zvinovaka muviri zvakakwana zvinodiwa nemuviri.
• Kushaikwa kwezinc.
• Kushaikwa kwemagnesium.
• Hypothyroidism: Kudzikira kwebasa regland regland.
• Zvirwere zvemajini zvisingawanzoitiki: Zvirwere zvisingawanzoitiki zvakaita se'Hypophosphatesia' uye 'chirwere cheWilson'.

Ndinofanira kunetseka here kana huwandu hwangu hweALP hwakakwira kana kuti hwakaderera?

Munhu mumwe chete pavanhu makumi maviri vane hutano hwakanaka anogona kunge aine mhedzisiro yekuongororwa inopfuura mwero wenguva dzose. Zvimwe zvinhu zvinogona kukanganisawo kukosha kweALP.

• Mimwe mishonga: Mimwe mishonga, yakaita semapiritsi ekudzivirira pamuviri.
• Kudya kwako.
• Kubata pamuviri.
• Zera: Sezvatakambokurukura, kukosha kwevana vari kukura kwakanyanya.
• Kukanganisa kunoitika panguva yekutorwa, kutakurwa, kana kuongororwa kweropa.

Saka, chiremba wako haazomboiti sarudzo zvichibva pahuwandu hweALP chete. Achafunga nezvezvinhu zvinotevera:

• Nhoroondo yako yese yezvekurapa.
• Mishonga ipi yauri kutora parizvino?
• Kuti kukosha kweALP yako kwakakwira kana kuderera zvakadii.
• Mhedzisiro yemimwe miedzo yakaongororwa pamwe chete neALP (semuenzaniso ALT, GGT, Bilirubin).
• Une zviratidzo here?

Kuisa zvese izvi pamwe chete kucharatidza kana uchida kuongororwazve kana kurapwa.