Chii chinonzi Evans Syndrome? Ngatitaurei nezvazvo!

Dzimwe nguva unonzwa kuneta here? Kana kuti unoomerwa nekumira kubuda ropa kunyangwe kubva pazvinhu zvidiki diki? Pamwe imhaka yekuti masoja emuviri wako ari kushanda achikurwisa. Nhasi tichataura nezvechirwere chisingawanzoitiki asi chakakosha chekuziva nezvacho. Ndiyo Evans Syndrome . Usazvidya moyo, tichataura nezvese zviri nyore.

Saka, chii chinonzi Evans Syndrome?

Zvichitaurwa zviri nyore, Evans Syndrome chirwere chinokonzerwa ne autoimmune system . Chinoitika ndechekuti masoja anofanirwa kuchengetedza miviri yedu, masoja ekudzivirira muviri, anotanga kuparadza mamwe masero edu eropa netsaona. Zvakafanana neuto redu richirwisa vanhu vedu. Nekuda kweizvozvo, miviri yedu inorasikirwa nehuwandu hunodiwa hwemasero eropa. Kudzikira uku kusingawanzoitiki kwemasero eropa ndiko kwatinodaidza kuti cytopenia mukurapa.

Vanhu vazhinji vane Evans Syndrome vanotanga vabatwa nemasero matsvuku eropa asina kusimba (chirwere chinonzi anemia ) uye maplatelet (chirwere chinonzi thrombocytopenia ). Pamusoro pezvose, vamwe vanhu vanogonawo kuva nenhamba shoma yemasero machena eropa anonzi neutrophils (chirwere chinonzi neutropenia ).

Kana marudzi aya emasero eropa akaderera, zvinhu zvakawanda zvakakosha mumuviri wedu, zvakaita sekuwana okisijeni, kugomara kweropa, uye kurwisa zvirwere, zvinokanganiswa. Ndosaka tichinzwa tisina simba, kuneta, kutanga kubuda ropa zviri nyore, uye kurwara kakawanda .

Chirwere ichi chinogona kubata vamwe vanhu zvishoma, nepo vamwe vachigona kuva vakakomba. Uye migumisiro yacho haigari yakafanana muhupenyu hwavo hwese. Chinhu chakanakisa ndechekuti kunyangwe pasina mushonga wechirwere ichi, kurapwa kunogona kubatsira kudzora zviratidzo uye kuderedza mhedzisiro yacho .

Ndezvipi zviratidzo zveEvans Syndrome?

Zviratidzo zveEvans Syndrome zvinogona kusiyana zvakanyanya. Zvinoenderana nekuti une rudzii rwe cytopenia uye kuti yakanyanya sei. Kazhinji, anemia kana thrombocytopenia inotanga kuitika, uye zvimwe zvinozoonekwa gare gare.

Zviratidzo zvekutanga zvekushaikwa kwemasero matsvuku eropa ( anemia ):

Waneta here kunyangwe mushure mekufamba chinhambwe chipfupi? Uri kunzwa kuneta uye usingachakwanisi kuita zvawaimboita? Pamwe chiso chako chiri kutaridzika sechakachenuruka. Izvi ndizvo zvimwe zvezviratidzo zvekutanga zveanemia :

• Kungonzwa kuneta zvakanyanya.
• Ganda rakachenuruka (rakachenuruka) .
• Kusanzwisisa kana kuti dzungu .
• Kutadza kufema zvakanaka (dyspnea) .
• Kurova kwemoyo nekukurumidza (tachycardia) .
• Kunzwa kana kunzwa sekuti moyo wako uri kurova zvisina kujairika (kurova kwemoyo) .

Zviratidzo zvekutanga zvekushaikwa kwemaplatelet (thrombocytopenia):

Wakamboona here kuti dzimwe nguva madonhwe matsvuku anoonekwa paganda rako? Kana kuti unongoerekana wava nemavanga mumuviri wako wese? Unonzwa sekunge mazino ako ari kubuda ropa kupfuura zvawagara uchiita paunokwesha mazino ako? Izvi ndizvo zviratidzo zvinogona kunge zvakaita semaplatelet asina kusimba:

• Mavara madiki matsvuku ekubuda ropa (petechiae) pasi peganda.
• Mavara epepuru paganda (purpura) .
• Kukuvara (ecchymosis) kunoitika pasina chikonzero.
• Kubuda ropa rakawanda kubva mumazino kana mumhino.
• Kubuda ropa rakawanda panguva yekuenda kumwedzi kuvakadzi.
• Kubuda ropa netsvina kana weti.

Zviratidzo zve neutropenia (izvi zvinogona kuitika kana kusazoitika gare gare):

Zvakajairika kuti munhu anzwe dzihwa kamwe chete kana kaviri pamwedzi. Asi unowanzorwara nefivha here? Unogara uine maronda mumuromo here? Zvinoita sekunge zvinotora nguva yakareba kuti zvipore here? Heano zvimwe zvinhu zvinogona kuitika kana ma neutrophils ako akaderera:

• Kupindwa nechando.
• Maronda emuromo.
• Dzihwa, fivha, uye kurwadziwa mudumbu nguva nenguva.
• Kurwara nenzeve kunowanzoitika.
• Utachiona hwefungus kwenguva refu.
• Utachiona hwemunzira yeweti (UTIs) .

Zvimwe zviratidzo zveEvans Syndrome (izvi zvinogona kuitika dzimwe nguva):

• Ma lymph nodes akazvimba mumutsipa.
• Chidende chakakura .
• Chiropa chakakura .
• Jaundice .

Sei Evans Syndrome ichiitika?

Sezvatakambotaura, Evans Syndrome chirwere chinokonzerwa ne autoimmune . Izvi zvinoreva kuti masoja emuviri wedu anoona mamwe masero edu eropa zvisirizvo se "muvengi" uye otanga kuarwisa.

Basa iri rinoitwa nemasero eB, rudzi rwakakosha rwesero muimmune system yedu. Masero aya eB anogadzira chimwe chinhu chinonzi ma antibodies . Ma antibodies aya anoenda kunobata masero eropa asina mhosva oaparadza. Kazhinji, anotanga kurwisa rudzi rumwe rwesero reropa, uye ozotanga kurwisa mamwe marudzi emasero eropa.

Maitiro aya ndiwo anopedzisira akonzera kuti uve nekushomeka kwemasero eropa maviri (cytopenia), uye dzimwe nguva ese ari matatu. Kushomeka kwemasero ese ari matatu kunonzi pancytopenia . Matambudziko matatu makuru ayo masero eropa aya anenge akaderera ndeaya:

• Kushaya simba kwemuviri (Autoimmune hemolytic anemia) (AIHA): Apa ndipo panodzikira masero matsvuku eropa. Kureva kuti, anoparadzwa nekukurumidza kupfuura zvingagadzirwa nemuviri.
• Immune thrombocytopenia (ITP) : Ichi chirwere chinoratidza kudzikira kwemaplatelet. Masoja emuviri anorwisa nekubvisa maplatelet muropa.
• Autoimmune neutropenia (AIN) : Ichi chirwere chinowanzoita kuti huwandu hwema neutrophils, rudzi rwemasero machena eropa, huderere. Masoja emuviri anorwisa nekuparadza ma neutrophils.

Funga nezvazvo, panogona kunge paine zvikonzero zvakawanda zvinoita kuti ropa rive shoma (cytopenia). Dzimwe nguva zvinogona kunge zvichikonzerwa nekuti mupfupa hausi kugadzira masero eropa akakwana. Zvisinei, mu autoimmune cytopenia, masoja emuviri anoparadza masero awo eropa.

Ndezvipi zvinokonzera Evans Syndrome?

Masayendisiti haasati aziva kuti sei zvirwere izvi zve autoimmune zvichiitika. Asi vakaona kuti zvirwere izvi zvinowanzotanga mushure mekurwara zvakanyanya kana chiitiko chinoisa kushushikana kwakanyanya pamasimba emuviri. Izvi zvinonzi zvinokonzera .

Uyewo, kana uine chirwere chimwe chete chinokonzerwa ne autoimmune, une mukana wekuti utange chimwe. Zvinoita sekunge chirwere ichi che immune system chinopararira kubva kune imwe nhengo yemuviri kuenda kune imwe.

Evans syndrome inogona kuitika yoga (iyi inonzi primary Evans syndrome ), kana kuti inogona kuitika sechirwere chechipiri chine chekuita nechimwe chirwere (iyi inonzi secondary Evans syndrome) . Mamwe ematambudziko anogona kusanganiswa nenzira iyi ndeaya:

• Systemic lupus erythematosus (lupus)
• Kusagadzikana kwemuviri kunowanzochinja-chinja
• Kushaikwa kweIgA yekusarudza
• Chirwere cheSjögren
• Non-Hodgkin lymphoma
• Leukemia isingaperi yelymphocytic
• Chiropa chisingaperi chehepatitis C
• Utachiona hweHIV husingaperi

Kana uine chirwere cheprimary Evans syndrome, chinogona kunge chakaitika mushure mekurwara kwenguva pfupi, kana kuti ungasava nechikonzero chakajeka chinochikonzera. Masayendisiti anoisa chirwere cheEvans muchikamu chechirwere chisingawanzoitiki . Izvi zvinoreva kuti hapana chikonzero chakawanikwa.

Ndezvipi zvinetso zvinogona kukonzera Evans Syndrome?

Havasi vese vane Evans Syndrome vanozosangana nematambudziko. Vamwe vanhu vane zviratidzo zvishoma chete. Zvisinei, muzviitiko zvakakomba, kushomeka kwemasero eropa (cytopenias) kunogona kuisa hupenyu panjodzi. Semuenzaniso:

• Kana pasina masero matsvuku eropa akakwana ekutakura okisijeni kuenda mumuviri, hapana okisijeni yakakwana muropa (hypoxemia) . Izvi zvinoomera mwoyo zvikuru uye zvinogona kukonzera chirwere chemwoyo uye kutadza kushanda kwemoyo.
• Kana usina maplatelet akakwana , anobatsira kuti ropa rako rigwambe, ropa rako harigwambe zvakanaka. Izvi zvinogona kukonzera kuti ubude ropa zviri nyore uye nekukurumidza. Izvi zvinogona kukonzera anemia yakanyanya.
• Kana muviri wako ukarasikirwa nema neutrophils , ayo anobatsira kurwisa hutachiona, une mukana wekuwana hutachiona kakawanda, uye hunogona kukura zvakanyanya uye kupararira mumuviri wako wese. Izvi zvinogona kutungamira kuchirwere chine njodzi chinonzi sepsis .

Vanachiremba vanoongorora sei Evans Syndrome?

Evans Syndrome inoratidzwa kuburikidza nekuongororwa kweropa . Inogona kuonekwa kana ukava nezviratidzo zve cytopenia, kana panguva yekuverengwa kwemasero eropa kunoitwa panguva yekuongororwa kwehutano nguva dzose.

Kana huwandu hweropa rako (CBC) huchiratidza kuti une masero matsvuku eropa, maplatelet, kana ma neutrophils mashoma, timu yako yezvekurapa ichaita bvunzo dzakawanda. Semuenzaniso, vachaongorora ropa rako kuti vaone kana paine ma antibodies akakwira ane chekuita neEvans Syndrome. Vachaongororawo zvimwe zvirwere zvinogona kukonzera cytopenia, zvakaita sehutachiona kana kenza.

Vanachiremba vanosimbisa Evans Syndrome nekuramba zvimwe zvikonzero zvese. Dzimwe nguva, vangangodawo kuita CT scan (computed tomography scan) kana bone marrow biopsy kuti vaone kana paine zvimwe zvirwere.

Pane mushonga wakakwana weEvans Syndrome here? Inorapwa sei?

Kutaura zvazviri, hapana mushonga wakakwana weEvans Syndrome, kana chimwe chirwere che autoimmune. Vanachiremba vanorapa zvirwere izvi zve autoimmune nekukupa mishonga inoderedza kushanda kwe immune system yako.

Uyezve, zviratidzo zvako zvinogona kurapwa zvakasiyana. Semuenzaniso, kana huwandu hwemasero eropa rako hwakaderera zvikuru, chiremba wako anogona kugadzirisa izvi nekuwedzerwa ropa dzimwe nguva.

Kufanana nezvirwere zvakawanda zve autoimmune zvinogara kwenguva refu, Evans Syndrome inogona kuramba ichiipa nekufamba kwenguva. Dzimwe nguva zviratidzo zvinogona kuita sezviri kupera (zvinonzi relievement) , asi zvino zvinogona kudzoka kana kutowedzera kuipa (zvinonzi relapse ).

Ungangoda kuedza mishonga yakasiyana-siyana muhupenyu hwako hwese, sezvo kubudirira kwayo kunogona kusiyana nekufamba kwenguva. Chiremba wako achaedza kukudzivirira kubva kumatambudziko akakomba eEvans Syndrome.

Ndezvipi zviri kurapwa?

Mishonga inowanzo shandiswa yekurapa Evans Syndrome ndeyekudzora immune system uye, kana zvichidikanwa, kuwedzerwa ropa. Mishonga iyi inoshanda nekuderedza kurwiswa kusingatarisirwi nemasoja emuviri wako.

Mhando huru dzemishonga dzinopihwa:

• Corticosteroids , yakadai seprednisone . Iyi ndiyo nzira yekutanga yekurapa.
• Kurapa ne intravenous immunoglobulin (IVIg) kunosanganisira kupa mushonga une ma antibodies evanhu kuburikidza netsinga. Ma antibodies matsva aya anogona kusunga ma antibodies e autoimmune asina kunaka uye oadzima.

Kana ukasagamuchira zvakanaka mishonga yakajairika, chiremba wako anogona kuedza mimwe mishonga. Idzi dzinosanganisira:

• Ma antibodies eMonoclonal , akadai serituximab . Aya ma antibodies akagadzirwa murabhoritari. Dzimwe nguva aya anogona kumisa mhinduro ye autoimmune. Chiremba wako anogona kukukurudzira kana mimwe mishonga isingashande.
• Kubviswa kwetsvina . Kana paine zviitiko zvakakomba, chiremba wako anogona kukurudzira kuvhiyiwa kubvisa tsandanyama yako. Tsandanyama yako ndipo panobviswa masero eropa ekare. Saka kana tsandanyama yabviswa, maitiro acho anononoka zvishoma.

Pane matambudziko kana migumisiro yekurapwa here?

Kana ukatora mishonga inodzvinyirira muviri, mhinduro yemuviri wako kuchirwere chako che autoimmune inodzikira. Zvisinei, kudzivirirwa kwako kuzvirwere kunodzikirawo . Saka uchafanira kutora matanho akakosha ekudzivirira kurwara.

Chiremba wako anogona kukurudzira mamwe majekiseni pamusoro peaya awakatogamuchira. Kana masoja emuviri wako asina simba (asina simba rekudzivirira muviri), unogona kunge uri panjodzi yekubatwa nezvirwere zvausingawanzo kuwana.

Kurarama neEvans Syndrome kunokanganisa hupenyu hwemunhu here?

Evans Syndrome haikanganisi hupenyu hwako. Vamwe vanhu vane zviratidzo zvishoma, dzimwe nguva. Zvisinei, mamwe matambudziko, akadai sekubuda ropa, chirwere chemwoyo, uye hutachiona, anogona kuisa hupenyu panjodzi.

Kana uine chirwere chechipiri cheEvans syndrome, zvichireva kuti une chimwe chirwere chisingaperi, izvozvo zvinogonawo kukanganisa hupenyu hwako. Ungave uine matambudziko anotyisidzira hupenyu anouya nechimwe chirwere chako.

Chii chiri kutarisirwa nemunhu ane Evans Syndrome?

Zvinoitika kuvanhu vane Evans Syndrome zvinosiyana zvikuru. Zviratidzo zvinogona kuva zvishoma kana zvakanyanya. Vamwe vanhu vanonzwa sekunge zviratidzo zvavo zvinopera zvachose (relief). Vamwe vanozozviona zvakare gare gare (relapse).

Vanhu vazhinji vanoda imwe nzira yekurapwa uye kuongororwa nguva nenguva nachiremba. Kurapwa kunowanzo shanda zvakanaka, asi kwete nguva dzose. Dzimwe nguva, kushanda kwekurapa kunogona kuita sekunoderera nekufamba kwenguva. Ungangoda kuedza dzimwe nzira dzekurapa.

Ndingazvitarisira sei ini ndichirarama neEvans Syndrome?

Kana uine Evans Syndrome, zvakakosha kuti ugare uchiongororwa nachiremba nguva dzose . Kunyangwe uchinzwa zvakanaka, chiremba wako achada kutarisa mamiriro ako uye achaaona nekukurumidza kana akanyanya kuipa.

Uyewo, unofanira kugara uchizvichenjerera uye uchitarisa zviratidzo zvitsva. Kana uine dzihwa risingachaperi, kana kuti uine kubuda ropa kusingadzoreki, fonera chiremba wako nekukasika .

Mibvunzo ipi yandinofanira kubvunza chiremba wangu?

Ungada kubvunza chiremba wako mibvunzo yakaita seiyi:

• Ndeapi marudzi emasero eropa andisina?
• Zvakaderera zvakadii?
• Ndezvipi zviratidzo kana zviratidzo zvinonyevera zvandinofanira kutarisa?
• Ndingaziva sei kana kurapwa kuri kushanda kana kuti kwete?
• Chii chinoitika kana kurapwa kusingashande?
• Ndinofanira kubhuka riini nguva yangu inotevera yekuonana nachiremba?

Evans Syndrome chirwere chisingawanzoitiki chaungave usina kumbonzwa nezvacho. Zviratidzo zvacho zvinogona kunge zvisinganzwisisike uye zvichinetsa. Kunzwisisa zviri kuitika uye zvazvinoreva kunogona kuva chinhu chinonetsa.

Kunyange zvazvo Evans Syndrome iri chirwere chehupenyu hwese, haisi nguva dzose yakafanana. Ramba uine tariro yekuti uchanzwa zviri nani, dzimwe nguva. Pasinei nekuti unonzwa sei, timu yako yezvekurapa ichavepo kuti ikupe rubatsiro rwaunoda.

Mharidzo Yekupedzisira Yekuenda Kumba

Zvakanaka, saka ngatikuyeuchidzei zvimwe zvezvinhu zvakakosha zvatataura nezvazvo.

• Chii chinonzi Evans Syndrome?Chirwere chisingawanzoitiki apo masoja emuviri wako anorwisa masero ako eropa.
• Izvi zvinogona kukonzera kudzikira kwemasero matsvuku eropa ( anemia ), maplatelet (thrombocytopenia), uye pamwe ma neutrophils (neutropenia) .
• Zviratidzo zvakaita sekuneta zvakanyanya, kucheneruka, mavanga ari nyore, kubuda ropa nguva nenguva, uye hutachiona hunowanzoitika zvinogona kuitika.
• Kunyange zvazvo pasina mushonga wakakwana weizvi, zviratidzo zvinogona kudzorwa nekurapwa .
• Zvakakosha kutevedzera mazano echiremba nguva dzose uye kuteerera zviratidzo.
• Hausi wega. Vanachiremba vako nevadikanwi vako vachakubatsira. Zvakakoshawo kuti ugare uine tariro.

Ndinovimba ruzivo urwu ruchakubatsira. Kana uine mibvunzo, usazeza kutaura nachiremba wako.

Evans syndrome, chirwere che autoimmune, cytopenia, anemia, thrombocytopenia, neutropenia, matambudziko eropa