Chiremba wako akakunyorera here kana mumwe munhu waunoziva piritsi rinonzi Guanidine? Ungangoda kuziva, kana kutotya, paunonzwa zita iri. Nekuti uyu hausi mushonga watinowanzo nzwa nezvawo. Guanidine mushonga unoshandiswa kurapa chirwere chakasiyana uye chisingawanzoitiki. Saka, zvakakosha kuziva izvi. Saka, nhasi tichataura nezvemapiritsi aya eGuanidine, mamiriro ekurapa aanorapa, mashandisirwo awo, uye zvinhu zvekungwarira.
Chii chinonzi Guanidine uye chirwere chipi chainorapa?
Zvichitaurwa zviri nyore, Guanidine mushonga unokurudzira tsinga uye unovandudza mashandiro emhasuru. Panyaya dzezvekurapa, uri muboka remishonga inonzi `cholinergic muscle stimulants`.
Mushonga uyu unonyanya kushandiswa kurapa chirwere chisingawanzoitiki che autoimmune chinonzi Lambert-Eaton Myasthenic Syndrome (LEMS) .
Ngatinzwisisei zvishoma nezve LEMS.
Fungidzira, kufamba kwemuviri wedu kunodzorwa nemashoko anobva kuuropi. Kana mashoko aya achifamba nemutsinga osvika mutsandanyama, tinokwanisa kufambisa maoko nemakumbo edu nekufamba. Panosangana tsinga netsandanyama, kemikari inonzi `Acetylcholine` inoburitswa kubva kumagumo etsinga. Kana kemikari iyi yasvika mutsandanyama, tsandanyama inogumira, kureva kuti, inoshanda.
Asi mumunhu ane LEMS, masoja emuviri anorwisa tsinga idzodzo zvisirizvo. Nekuda kweizvozvo, huwandu hwe'Acetylcholine' hunodiwa hahuburitswe. Mugumisiro wacho kushaya simba kwakanyanya uye kuneta kunokonzerwa netsandanyama dzisingagamuchire shoko nemazvo. Kushaya simba kwetsandanyama kunonyanya kuitika mumakumbo nemuhudyu.
Guanidine inoshanda nekukurudzira kuburitswa kwemutumwa wemakemikari (Acetylcholine) kubva mutsinga. Izvi zvinoreva kuti inosimudzira kufamba kwemashoko kwakavharika uye inobatsira tsandanyama kushanda zvakanaka zvakare.
Zvinhu zvaunofanira kuudza chiremba wako usati watanga mushonga
Guanidine mushonga unofanirwa kushandiswa nekungwarira. Saka, zvakakosha kuzivisa chiremba wako nezvenhoroondo yako yese yezvekurapa usati wanyora mushonga uyu. Iva nechokwadi chekuvaudza kana uine chimwe chezvirwere zvinotevera:
- Chirwere cheitsvo: Unofanira kuudza chiremba wako kana uine chero chirwere chine chekuita neitsvo, sezvo itsvo dzichiita basa guru mukubvisa mushonga uyu mumuviri.
- Chirwere chechiropa: Kana paine kusasimba kwechiropa, taurawo nezvazvo.
- Matambudziko emasero eropa: Kana wakambonzi une masero machena eropa, masero matsvuku eropa, kana maplatelet mashoma muropa rako, irworwo ruzivo rwakakosha zvikuru.
- Kurwara Nepfungwa: Kana uri kurapwa kana kuti une nhoroondo yechirwere chepfungwa, ndapota tizivise.
- Kurwara: Kana uine allergies kune guanidine kana chero imwe mishonga, chikafu, kana dhayi.
- Kubata pamuviri kana kutarisira mwana: Kana uine pamuviri kana kuti uchironga kubata pamuviri, izvi zvinofanira kutaurwa nezvazvo.
- Kuyamwisa: Udzawo chiremba kana uri amai vanoyamwisa.
Ndinofanira kushandisa mushonga uyu sei?
Chinhu chinonyanya kukosha ndechekutevera mirairo yachiremba wako panguva chaiyo yekushandisa mushonga uyu.
- Medza piritsi iri negirazi remvura.
- Shandisa mushonga wacho sezvakarairwa papepa remushonga. Usatore mushonga wakawanda kana kuti mudiki pane waunoudzwa nachiremba wako kuti utore.
- Izvi zvinogona kutorwa usati wadya kana kuti wapedza kudya. Zvisinei, kana ukasangana nedambudziko remudumbu, kuritora pamwe chete nechikafu kunogona kubatsira kuderedza dambudziko racho.
- Iva netsika yekutora mushonga wako panguva imwe chete zuva nezuva, nenguva.
- Chinonyanya kukosha: Usarega kutora mushonga wako chero chikonzero chipi zvacho usina kurairwa nachiremba wako. Kurega kamwe kamwe kunogona kukonzera kuti zviratidzo zvako zvidzokere uye zviwedzere kuipa.
- Kana ikapihwa vana: Pakupa mushonga uyu kuvana, zvakakosha kubvunza chiremba wevana.
Ko kana ndikatora mushonga wakawandisa? (Kunyanya kunwa mushonga)
Kana uchifunga kuti ungangove wakatora mushonga wakawanda kupfuura zvaunofunga netsaona, usanonoka. Fonera National Poisons Information Centre paColombo National Hospital nekukasika, kana kuenda kuEmergency Treatment Unit (ETU) yechipatara chiri pedyo.
Ngatidzidzeiwo nezvemigumisiro uye kupindirana kwayo.
Kufanana nemushonga upi zvawo, Guanidine inogona kukonzera migumisiro yakaipa. Inogonawo kupindirana nemimwe mishonga.
Migumisiro inogona kuitika
Zvimwe zvacho zvinogona kunge zvakakomba, zvimwe zvinowanzoitika. Zvakakosha kuziva nezvazvo.
| Rudzi rwemhedzisiro yakaipa | Hunhu |
|---|---|
| Migumisiro yakakomba inoda kurapwa nekukurumidza | |
| Kusawirirana kwemuviri | Kutsamwiswa kweganda, kuvaviwa, kuzvimba |
| Matambudziko ekufema | Kuoma kufema |
| Kuchinja kwekurova kwemoyo | Kurova kwemoyo nekukurumidza kana kusina kurongeka |
| Zviratidzo zvehutachiona | Fivha, pahuro panorwadza |
| Kuchinja kwepfungwa | Kuona kana kunzwa zvinhu zvisiri zvechokwadi (Hallucinations) |
| Matambudziko eWeti | Kuomerwa nekuita weti kana kuchinja huwandu hweweti yaunoburitsa |
| Kusasimba kusingawanzoitiki | Kunzwa kuneta kwakanyanya uye kushaya simba mumuviri |
| Mhedzisiro pachiropa | Kutsvuka kwemaziso kana ganda (senge jaundice) |
| Migumisiro inowanzo fanira kutaurwa kuna chiremba kana ikaramba iripo | |
| Hunhu hwakawanda | Muromo wakaoma, dzungu, musoro, dumbu rinogumbuka, kuda kurutsa/kurutsa, manyoka, kushaya chishuwo chekudya |
| Mhedzisiro pahurongwa hwetsinga | Kunzwa kusanzwa, kukwenya, kana kurwadziwa mumakumbo, kuchinja kwemanzwiro |
Mimwe mishonga inobatanidzwa neGuanidine (Kudyidzana Kwemishonga)
Mimwe mishonga yauri kutora inogona kukanganisa mashandiro anoita Guanidine. Saka udza chiremba wako nezvemishonga yese yauri kutora (kusanganisira mavhitamini nezvimwe zvinogadzirwa nemiti), kunyanya kana uri kutora chero ipi zvayo yeiyi inotevera:
- Mimwe mishonga inotorwa yegomarara
- Mishonga inopiwa kudzora dziviriro yemuviri mushure mekuisirwa nhengo
- Mimwe mishonga yekurapa pfari (semuenzaniso, `Carbamazepine`)
- Mishonga yekurapa zvirwere zvepfungwa yakaita se "Clozapine"
- Mishonga yePhenothiazines (semuenzaniso Chlorpromazine)
- Mishonga yemhando yesteroid (semuenzaniso `Prednisone`, `Cortisone`)
- 'Sulfinpyrazone'
Rangarirai kuti runyorwa urwu haruna kukwana, saka kuti muve vakachengeteka, zvakanaka kuudza chiremba wenyu nezvese zvamuri kutora.
Mharidzo Yekuenda Nayo Kumba
- Guanidine mushonga unoshandiswa kurapa chirwere chisingawanzoitiki, chetsinga dzetsinga chinonzi Lambert-Eaton Myasthenic Syndrome (LEMS).
- Iva nechokwadi chekuudza chiremba wako nezvemishonga yese yauri kutora, kunyanya kana uine matambudziko eitsvo, chiropa, kana ropa.
- Haufanire kutanga, kurega, kana kuchinja mushonga usina kurairwa nachiremba wako.
- Kana ukasangana nematambudziko akakomba akadai sekuoma kwekufema, kuchinja kwekurova kwemoyo, kutsvuka kwemaziso, kana fivha, tsvaga rubatsiro rwechiremba nekukasika.
- Kana uchifungidzira kuti washandisa zvinodhaka zvakadarika mwero, enda kuNational Poisons Information Centre kana kuEmergency Department (ETU) yechipatara nekukasika.
- Chengeta mushonga uyu panzvimbo yakachengeteka patembiricha yemumba, kure nevana.
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