Tose takambonzwa nezvekushaikwa kwesimbi, zvinoreva anemia, handiti? Tinowanzo nzwa mazano ekudya sipinachi, kudya sipinachi, uye kunwa mapiritsi esimbi. Asi wakambofunga here nezvezvinoitika kana paine simbi yakawandisa mumuviri? Ehe, izvozvo zvinogonawo kuva dambudziko guru. Ndizvo zvatinodaidza kuti Hemochromatosis mukurapa, kana kuti Iron Overload. Nhasi, tichataura nezveizvi zvakadzama, zviri nyore.
Zvichitaurwa zviri nyore, chii chinonzi Hemochromatosis?
Funga nezvemuviri wako senzvimbo yekuchengetera zvinhu. Tinotora zvinovaka muviri zvatinoda kubva muchikafu chatinodya nekunwa. Iron ndeimwe yezvinovaka muviri zvakakosha. Iron inokosha zvikuru pakugadzira masero matsvuku eropa muropa redu uye kupa muviri wedu simba. Asi sezvimwe zvinhu zvese, iron yakawandisa inogona kuva dambudziko kana ikatorwa yakawandisa.
Dambudziko reHemochromatosis ndiro dambudziko. Mumamiriro ezvinhu aya, muviri wako unotora iron yakawanda kupfuura yaunoda kubva muchikafu. Dambudziko nderekuti, muviri wedu hauna nzira yekubvisa iron yakawanda iyi. Saka muviri unoita sei? Iron yakawanda iyi inotanga kuungana munhengo dzinokosha dzakadai sechiropa, moyo, nepancreas. Zvakafanana nekuchengeta zvinhu zvatisingashandisi muwadhiropu. Nekufamba kwenguva, iyi iron yakaunganidzwa inotanga kukuvadza nhengo idzodzo uye kukanganisa mashandiro adzo. Kana ikasarapwa, inogona kutyisidzira hupenyu. Asi mashoko akanaka ndeekuti kana ikaonekwa nekukurumidza, chirwere chinogona kudzorwa zvachose.
Zviratidzo zvacho ndezvipi? Zvinoonekwa riini?
Chimwe chezvinhu zvinoshamisa zvechirwere ichi ndechekuti zvinotora nguva yakareba kuti zviratidzo zvioneke. Kunyangwe chirwere ichi chichiwanzoitika kuzvarwa nacho, zviratidzo zvinongoonekwa chete kana iron yaungana mumuviri yotanga kukuvadza nhengo dzemuviri. Izvi zvinogona kutora makore. Vanhu vazhinji havaratidzi zviratidzo kusvika vava nemakore 40-50. Vamwe vanhu vane chirwere chisina kusimba uye vanogona kusaratidza zviratidzo kwehupenyu hwavo hwese.
Ngationei kuti zviratidzo zvikuru ndezvipi.
| Chiratidzo | Tsananguro iri nyore |
|---|---|
| Kuneta nguva dzose | Kunzwa kuneta nguva dzese pasina chikonzero. Kunyangwe mushure mekurara zvakanaka, uchiri kunzwa kuneta. |
| Kurwadziwa kwemajoini | Kurwadziwa, kunyanya muzvigunwe zveminwe, munwe wekunongedza, nepakati. Izvi zvinonziwo "chibhakera chesimbi." |
| Kusviba kweganda | Ganda rinova neruvara rwegrey kana bronze. |
| Mwoyo unovhunduka | Kunzwa sekuti moyo wako uri kurova nekukurumidza, sekunge uri kubhururuka muchipfuva chako (arrhythmias). |
| Kuderera kwechido chepabonde | Varume nevakadzi vanogona kunzwa kuda kuita zvepabonde kushoma. Varume vanogonawo kunzwa kusashanda zvakanaka kwepabonde. |
| Marwadzo emudumbu repamusoro | Panogona kuva nekurwadziwa pasi pembabvu kurudyi, uko chiropa chiri. |
| Kuderedza uremu pasina chikonzero | Kana uri kudzikira uremu usingade kudya zvakanyanya kana kurovedza muviri, unofanira kunetseka. |
Sei izvi zvichiitika? Ndezvipi zvikonzero?
Kune zvikonzero zviviri zvikuru zveizvi.
1. Chikonzero chikuru: Hereditary Hemochromatosis
Vanhu vazhinji vanorwara nechirwere ichi nekuda kwekusakwana kwemajini, kureva kuti, shanduko diki mumajini anogara nhaka kubva kuvabereki vese.
Ingozvifunga seizvi. Kune jini rakakosha rinodzora kupinza kwesimbi mumuviri wedu. Tinoridaidza kuti `(HFE gene)`. Mwana wese anowana kopi imwe chete yejini iri kubva kuna amai vake uye kopi imwe kubva kuna baba vake. Kuti pave ne hemochromatosis, panofanira kunge paine chikanganiso mukopi yejini kubva kuna amai vake uye kopi yejini kubva kuna baba vake.
Fungidzira uchiwana bhuku rimwe chete kubva kuna amai vako nerimwe kubva kuna baba vako. Kuti chirwere ichi chiitike, mabhuku ese ari maviri anofanira kunge aine kachikanganiso kadiki papeji kanodzora simbi. Kana bhuku rimwe chete riine kachikanganiso, unenge uri mutakuri wechirwere. Hauzoiti chirwere chacho.
Saka, kunyangwe vabereki vese vari ivo vane jini iri risina kunaka, vanogona kunge vasina zviratidzo. Zvisinei, kana mwana wavo akagamuchira makopi ese ari maviri ejini iri risina kunaka, mwana anogona kutanga chirwere ichi. Mhando mbiri huru dzezvikanganiso zvinoonekwa mu `(HFE gene)` ndi `(C282Y)` uye `(H63D)`.
Pamusoro pezvo, kune rudzi rusingawanzoonekwi runonzi ``Juvenile Hemochromatosis`` runoonekwa pazera diki, kureva kuti, pakati pemakore 15-30. Runokonzerwa nekuchinja kwemajini mamwe ``(HJV, HAMP)``.
2. Zvinokonzereswa nezvimwe zvirwere (Secondary Hemochromatosis)
Dzimwe nguva, kuwanda kwesimbi kunogona kukonzerwa nechimwe chirwere kana kurapwa. Izvi hazvisi zvenhaka.
- Kuwedzerwa ropa kakawanda: Vanhu vane mamwe matambudziko eropa (akadai seanemia akadai sethalassemia) vanowanzoda kuwedzerwa ropa. Kana ropa rikapihwa nenzira iyi kwenguva yakareba, simbi iri muropa iroro inogona kuungana mumuviri, zvichikonzera chirwere ichi.
- Chirwere chechiropa chakakomba: Chiropa ndicho chikamu chikuru chinodzora kushandurwa kwesimbi mumuviri wedu. Kana chiropa chikakuvara zvakanyanya (semuenzaniso cirrhosis), chingasakwanise kubata simbi zvakanaka uye chinogona kuungana mumuviri.
- Kunwa doro zvakanyanya: Doro haringokanganisi chiropa chete, asi rinowedzerawo kunwa kwesimbi mumuviri.
Iron yakawandisa inogona kukuvadza muviri sei?
Sezvatakambotaura, simbi yakawandisa inouraya muviri. Iyi simbi inoungana zvishoma nezvishoma munhengo dzemuviri yotanga kudzikuvadza. Izvi zvinogona kukonzera matambudziko akakomba.
| Nhengo huru dzemuviri dzakabatwa | Matambudziko akakomba anogona kuitika |
|---|---|
| Chiropa | Chiropa chakakura, chiropa chine mafuta akawanda, kuoma kwechiropa (cirrhosis) uye mukana wekuwedzera wekenza yechiropa. |
| Mwoyo | Kukundikana kwemoyo kwakakombama, arrhythmias. |
| Pancreas | Kukuvadzwa kwepancreas kunogona kukonzera kusagadzikana kwekugadzirwa kwe insulin uye chirwere cheshuga. Izvi zvinonziwo "Diabetes Type 3c". |
| Majoini | Matambudziko eArthritis, kurwadziwa uye kuzvimba kwemajoini. |
| Mamwe magland | Kukuvadzwa kwemahomoni anogadzira mahormone, akadai sepituitary gland nethyroid gland, kunogona kukonzera kusawirirana kwemahomoni. |
Unoona sei izvi, Chiremba?
Kana uine chimwe chezviratidzo zvataurwa pamusoro apa kana kuti kana mumwe munhu mumhuri mako aine chirwere ichi, iva nechokwadi chekuona chiremba. Chiremba achatanga nekukubvunza mibvunzo mishoma uye achakuongorora.
- Bvunza kana vabereki vako kana mumwe munhu mumhuri mako ane iron yakawandisa kana chirwere chechiropa.
- Vanokubvunza kana uri kutora mapiritsi esimbi kana mavhitamini C ekuwedzera (vhitamini C inowedzera kupinza simbi mumuviri).
- Vanobvunza nezvehuwandu hwedoro raunonwa.
Mushure meizvozvo, bvunzo dzinoverengeka dzinoitwa kusimbisa chirwere.
- Kuongororwa kweropa: Uku ndiko kuongorora kuri nyore. Ropa rako richaongororwa kuti rione huwandu hwesimbi (Serum Iron), puroteni inochengeta simbi (Serum Ferritin), uye kuti puroteni inotakura simbi yakazara sei (Transferrin Saturation). Kana huwandu uhwu hwakakwira, hemochromatosis inogona kufungidzirwa.
- Kuongororwa kwemajini: Sampuro yeropa inogona kutorwa kuti ionekwe kana paine zvikanganiso mujini reHFE. Izvi zvinogona kubatsira kuona kana uine chimiro chawakatora nhaka.
- MRI scan: Izvi zvinogona kuyera kuti iron yakawanda sei iri muchiropa nemoyo pasina kurwadziwa.
- Kuongororwa kwechiropa: Mune zvimwe zviitiko, kuti zvionekwe kuti chiropa chakakuvara zvakadini, kanyama kadiki kanotorwa kubva pachiropa kachishandisa tsono diki koongororwa nemaikorosikopu.
Kurapa kwacho chii? Izvi zvinogona kurapwa here?
Ehe, kune mishonga inoshanda pakurapa izvi. Chinangwa chikuru chekurapa ndechekuderedza huwandu hwesimbi yakawandisa mumuviri, kuichengetedza iri padanho rakajairika, uye kudzivirira kukuvara kwenhengo dzemuviri.
Chinhu chakakosha ndechekuti chirwere ichi chikaongororwa nekukurumidza, kurapwa kwacho kunobudirira zvikuru. Kana kurapwa kukatanga nekukurumidza, kumwe kukuvara kwenhengo dzemuviri kunogona kutodzoserwa kumashure.
Kune nzira dzakawanda dzekurapa.
| Nzira yekurapa | Chii chinoitika kwairi? |
|---|---|
| Kurapa kwePhlebotomy | Uku ndiko kurapa kukuru uye kunoshanda zvikuru. Zvichitaurwa zviri nyore, zvakafanana nekupa ropa. Ropa diki (rinowanzoita 450-500 ml) rinobviswa mumuviri wako uchishandisa tsono. Ruzhinji rwesimbi mumuviri wedu ruri mumasero edu matsvuku eropa. Saka kana ropa rabviswa, simbi inobviswawo nayo. Pakutanga, ingangoda kuitwa kanenge kamwe chete pasvondo. Kana huwandu hwesimbi yako hwava pasi pesimba, ingangoda kuitwa kamwe chete pamwedzi mishoma. |
| Kurapa neIron Chelation | Vamwe vanhu (semuenzaniso, vane chirwere chemwoyo kana anemia) havagone kuwedzerwa ropa. Kurapa uku kunopiwa kuvanhu vakadaro. Izvi zvinosanganisira kupa mushonga unosunga iron wobvisa iron mumuviri uri muweti netsvina. Mushonga uyu unogona kutorwa sepiritsi kana kubaiwa jekiseni. |
| Kuchinja maitiro ekudya | Pamwe chete nekurapwa, unofanirawo kutarisira kudya kwako.
|
Mharidzo Yekuenda Nayo Kumba
- Hemochromatosis chirwere chinokonzerwa nesimbi yakawandisa mumuviri. Izvi zvinowanzo gara nhaka.
- Usafuratira zviratidzo zvakaita sekuneta nguva dzose, kurwadziwa kwemajoini, uye kutsvuka kweruvara rweganda, kunyanya kana wapfuura makore makumi mana.
- Chirwere ichi chinogona kukonzera kukuvara kukuru kunhengo dzinokosha dzakadai sechiropa, moyo, uye pancreas.
- Asi kana zvikaonekwa nekukurumidza uye zvikarapwa nemazvo, zvinogona kudzorwa zvakanaka uye unogona kurarama hupenyu hwakanaka uye hwakanaka.
- Kana muine kusava nechokwadi nezveizvi, kana kana mumwe munhu mumhuri yenyu aine chirwere ichi, iva nechokwadi chekutaura nachiremba wenyu.
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